AU4389096A - Production of cefotaxime and new sodium salts - Google Patents

Production of cefotaxime and new sodium salts

Info

Publication number
AU4389096A
AU4389096A AU43890/96A AU4389096A AU4389096A AU 4389096 A AU4389096 A AU 4389096A AU 43890/96 A AU43890/96 A AU 43890/96A AU 4389096 A AU4389096 A AU 4389096A AU 4389096 A AU4389096 A AU 4389096A
Authority
AU
Australia
Prior art keywords
cefotaxime
production
sodium salts
new sodium
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU43890/96A
Other versions
AU711228B2 (en
Inventor
Ingolf Macher
Gerhard Widschwenter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz GmbH
Original Assignee
Biochemie GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochemie GmbH filed Critical Biochemie GmbH
Publication of AU4389096A publication Critical patent/AU4389096A/en
Application granted granted Critical
Publication of AU711228B2 publication Critical patent/AU711228B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Paper (AREA)
AU43890/96A 1994-12-23 1995-12-22 Production of cefotaxime and new sodium salts Ceased AU711228B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT0239794A AT402928B (en) 1994-12-23 1994-12-23 NEW METHOD FOR PRODUCING CEFOTAXIM
AT2397/94 1994-12-23
PCT/EP1995/005088 WO1996020198A1 (en) 1994-12-23 1995-12-22 Production of cefotaxime and new sodium salts

Publications (2)

Publication Number Publication Date
AU4389096A true AU4389096A (en) 1996-07-19
AU711228B2 AU711228B2 (en) 1999-10-07

Family

ID=3533604

Family Applications (1)

Application Number Title Priority Date Filing Date
AU43890/96A Ceased AU711228B2 (en) 1994-12-23 1995-12-22 Production of cefotaxime and new sodium salts

Country Status (18)

Country Link
US (1) US5831086A (en)
EP (1) EP0799232A1 (en)
JP (1) JPH10511377A (en)
CN (1) CN1171110A (en)
AT (1) AT402928B (en)
AU (1) AU711228B2 (en)
BR (1) BR9510426A (en)
CA (1) CA2206518A1 (en)
CZ (1) CZ195097A3 (en)
FI (1) FI972265A (en)
HU (1) HUT77700A (en)
NO (1) NO972921L (en)
NZ (1) NZ298410A (en)
PL (1) PL320699A1 (en)
RU (1) RU2169150C2 (en)
SK (1) SK81597A3 (en)
TW (1) TW475932B (en)
WO (1) WO1996020198A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1286494B1 (en) * 1996-11-19 1998-07-15 Hichem Pharma S P A PROCEDURE FOR THE PREPARATION OF CEPHALOSPORANIC DERIVATIVES
KR100361828B1 (en) * 1997-04-16 2005-08-12 주식회사 엘지생명과학 Method for preparing cytotactile from reactive organic acid derivative
IT1295935B1 (en) * 1997-10-30 1999-05-28 Acs Dobfar Spa AMINOTHIAZOLE DERIVATIVES USEFUL IN THE PREPARATION OF B-LACTAMICS ANTIBIOTICS
WO2004063203A1 (en) * 2003-01-10 2004-07-29 Orchid Chemicals & Pharmaceuticals Ltd Process for the preparation of cefotaxime sodium
US7363525B2 (en) * 2004-10-07 2008-04-22 Cisco Technology, Inc. Bidirectional inline power port
WO2011042775A1 (en) * 2009-10-09 2011-04-14 Nectar Lifesciences Ltd. Process for preparation of cefotaxime acid
WO2011042776A1 (en) * 2009-10-09 2011-04-14 Nectar Lifesciences Ltd. Process for preparation of cefotaxime acid and pharmaceutically acceptable salt thereof
CN102702230B (en) * 2012-05-30 2014-09-10 华北制药河北华民药业有限责任公司 Method for preparing cefotaxime acid
CN103319504A (en) * 2013-06-28 2013-09-25 华北制药河北华民药业有限责任公司 Crystallization method for cefotaxime sodium
CN105646535B (en) * 2016-01-24 2018-01-23 哈尔滨合佳制药有限公司 The synthetic method of Cefotaxime Sodium
CN111647006B (en) * 2020-04-25 2021-06-08 广东金城金素制药有限公司 Cefotaxime sodium pharmaceutical preparation and treatment of salmonella infection indications including typhoid fever and paratyphoid fever

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE311519B (en) * 1962-12-14 1969-06-16 Astra Ab
US4138555A (en) * 1971-05-14 1979-02-06 Glaxo Laboratories, Limited (6R,7R)-7-[2-aryl-2-(etherified oximino)acetamido]-3-carbamoyloxymethylceph-3-em-4-carboxylic acid 1-oxides
US4093803A (en) * 1971-05-14 1978-06-06 Glaxo Laboratories Limited 7β-[2-Etherified oximino-2-(thienyl-, furyl- or pyridylacetamido)] cephalosporins
DK154939C (en) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd METHOD OF ANALOGUE FOR THE PREPARATION OF THIAZOLYLACETAMIDO-CEPHEM COMPOUNDS OR PHARMACEUTICAL ACCEPTABLE SALTS OR ESTERS THEREOF
DE2760123C2 (en) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporanic acids, their preparation and pharmaceutical compositions containing them
US4196205A (en) * 1976-01-23 1980-04-01 Roussel Uclaf 3-Acetoxymethyl-7-(iminoacetamido)-cephalosporanic acid derivatives
US5079369A (en) * 1976-04-12 1992-01-07 Fujisawa Pharmaceutical Company, Ltd. Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation thereof
DE2760484C2 (en) * 1976-04-14 1992-12-03 Takeda Chemical Industries, Ltd., Osaka, Jp
DE2714880A1 (en) * 1977-04-02 1978-10-26 Hoechst Ag CEPHEMDER DERIVATIVES AND PROCESS FOR THEIR PRODUCTION
FR2400519A1 (en) * 1977-08-17 1979-03-16 Roussel Uclaf CRYSTALLINE FORM OF SODIUM SALT OF AN OXIMIN DERIVATIVE OF 7-AMINO-THIAZOLYL ACETAMIDO CEPHALOSPORANIC, ITS PREPARATION PROCESS AND ITS APPLICATION AS A MEDICINAL PRODUCT
EP0037380B1 (en) * 1980-03-28 1984-09-12 BIOCHEMIE Gesellschaft m.b.H. New process for the production of cephalosporin antibiotics, and novel intermediates used in such process and their production
DE3173499D1 (en) * 1980-09-02 1986-02-27 Asahi Chemical Ind Novel thioesters and process for the preparation of the same
EP0075104A3 (en) * 1981-09-23 1984-11-28 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and intermediates
DE3377061D1 (en) * 1982-06-03 1988-07-21 Hoffmann La Roche Process for the preparation of 1-sulfo-2-oxoazetidine derivatives
US4652651A (en) * 1983-05-31 1987-03-24 Hoffmann-La Roche Inc. Process for the manufacture of 1-sulpho-2-oxoazetidine carboxylic acid intermediates via catalytic ester cleavage
IT8448798A0 (en) * 1983-09-12 1984-09-05 Biochemie Gmbh PROCEDURE FOR THE PREPARATION OF CEPHALOSPORIN-TYPE ANTIBIOTICS
EP0185220A3 (en) * 1984-12-19 1987-09-02 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Intermediates for the preparation of cephalosporins
DE3539901A1 (en) * 1985-11-11 1987-05-14 Hoechst Ag CEPHALOSPORINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION
AT383810B (en) * 1985-11-20 1987-08-25 Biochemie Gmbh METHOD FOR PRODUCING CEPHALOSPORINE DERIVATIVES
ATE77378T1 (en) * 1986-02-07 1992-07-15 Hoffmann La Roche PROCESS FOR THE PREPARATION OF CARBONIC ACID AMIDES.
IT1214587B (en) * 1986-12-23 1990-01-18 Giovanni Bonfanti METHOD FOR THE PRODUCTION OF PURE CRYSTALLINE PRODUCTS.
PL154046B1 (en) * 1987-12-07 1991-06-28 Os Bad Rozwojowy Biotechnologi Method of optaining 7-(2-/2-amino thiazol-4-ilo/-2-/z/-methoxyimine-acetamide0- derivatives of 3-substituted 3-cepho-4-carboxylic acid
CH674645A5 (en) * 1987-12-23 1990-06-29 Lonza Ag
ES2006988A6 (en) * 1988-06-20 1989-05-16 Gema Sa Process for preparing cephalosporins and intermediates therefor.
WO1992007840A1 (en) * 1990-11-02 1992-05-14 Taisho Pharmaceutical Co., Ltd. Thiazole thioester derivative
AT399877B (en) * 1992-02-20 1995-08-25 Biochemie Gmbh NEW METHOD FOR PRODUCING CEFTRIAXONE
US5574154A (en) * 1994-09-29 1996-11-12 Alnejma Bulk Pharmaceutical Co. A.B.P.C. Process for the preparation of cephalosporanic compounds

Also Published As

Publication number Publication date
BR9510426A (en) 1998-07-07
FI972265A0 (en) 1997-05-28
EP0799232A1 (en) 1997-10-08
NO972921D0 (en) 1997-06-20
TW475932B (en) 2002-02-11
ATA239794A (en) 1997-02-15
NO972921L (en) 1997-08-25
US5831086A (en) 1998-11-03
CZ195097A3 (en) 1997-10-15
AT402928B (en) 1997-09-25
CA2206518A1 (en) 1996-07-04
RU2169150C2 (en) 2001-06-20
JPH10511377A (en) 1998-11-04
WO1996020198A1 (en) 1996-07-04
MX9704641A (en) 1997-09-30
HUT77700A (en) 1998-07-28
NZ298410A (en) 1998-11-25
SK81597A3 (en) 1997-10-08
PL320699A1 (en) 1997-10-27
FI972265A (en) 1997-08-15
CN1171110A (en) 1998-01-21
AU711228B2 (en) 1999-10-07

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired