AU4295800A - Tissue culture system for the epithelialization or entothelialization and for functionally testing and supplying natural or artificial hollow organs or vessels under controlled sterile conditions for the purpose of surgical implantations - Google Patents
Tissue culture system for the epithelialization or entothelialization and for functionally testing and supplying natural or artificial hollow organs or vessels under controlled sterile conditions for the purpose of surgical implantationsInfo
- Publication number
- AU4295800A AU4295800A AU42958/00A AU4295800A AU4295800A AU 4295800 A AU4295800 A AU 4295800A AU 42958/00 A AU42958/00 A AU 42958/00A AU 4295800 A AU4295800 A AU 4295800A AU 4295800 A AU4295800 A AU 4295800A
- Authority
- AU
- Australia
- Prior art keywords
- tube
- tissue culture
- culture system
- entothelialization
- epithelialization
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 210000000056 organ Anatomy 0.000 title abstract 4
- 238000002513 implantation Methods 0.000 title 1
- 210000004204 blood vessel Anatomy 0.000 abstract 2
- 239000001963 growth medium Substances 0.000 abstract 2
- 230000002706 hydrostatic effect Effects 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/062—Apparatus for the production of blood vessels made from natural tissue or with layers of living cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/08—Flask, bottle or test tube
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/24—Gas permeable parts
Abstract
The invention relates to a tissue culture system for functionally testing natural or artificial hollow organs. A hollow organ (51) is located in a first tube (3), with a respective end of the hollow organ (51) being connectable to a cannula (1, 2) that is branched off from one end of the tube (3) in a tight manner. Said first tube (3) is located within a second tube (4). Said first tube (3) has holes (5) that link the space (28) that is enclosed by the first tube (3) with the chamber (77) between the first and the second tube. A gas-permeable duct (7) runs alongside the outer periphery of the first tube (3). The end sections (7', 7'') of said duct emerge from the chamber (77) in a gas-tight manner. A serum can be filled into the blood vessel (51) by means of a cannula (1) and the suspended cells of the patient can be injected in a predetermined concentration. A culture medium is filled into the chamber (77) and via the holes (5) into the space (28). The injected, suspended cells are removed and a culture medium is introduced into the blood vessel (51) that remains during the growth of the cells that are sedimented on the wall of the vessel while a hydrostatic excess pressure is maintained.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19918558 | 1999-04-23 | ||
DE19918558 | 1999-04-23 | ||
DE19938518 | 1999-08-13 | ||
DE19938518A DE19938518A1 (en) | 1999-04-23 | 1999-08-13 | Tissue culture system for epitheliating or endotheliating and functional examination and delivering of synthetic or natural hollow organs |
PCT/EP2000/003420 WO2000064569A1 (en) | 1999-04-23 | 2000-04-14 | Tissue culture system for the epithelialization or entothelialization and for functionally testing and supplying natural or artificial hollow organs or vessels under controlled sterile conditions for the purpose of surgical implantations |
Publications (1)
Publication Number | Publication Date |
---|---|
AU4295800A true AU4295800A (en) | 2000-11-10 |
Family
ID=26053058
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU42958/00A Abandoned AU4295800A (en) | 1999-04-23 | 2000-04-14 | Tissue culture system for the epithelialization or entothelialization and for functionally testing and supplying natural or artificial hollow organs or vessels under controlled sterile conditions for the purpose of surgical implantations |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1173272B1 (en) |
AT (1) | ATE232137T1 (en) |
AU (1) | AU4295800A (en) |
WO (1) | WO2000064569A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2407439C (en) * | 2000-04-27 | 2008-07-08 | Axel Haverich | Individual venous valve prosthesis |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5035708A (en) * | 1985-06-06 | 1991-07-30 | Thomas Jefferson University | Endothelial cell procurement and deposition kit |
CH675679A5 (en) * | 1987-12-07 | 1990-10-31 | Sulzer Ag | |
US4988623A (en) * | 1988-06-30 | 1991-01-29 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Rotating bio-reactor cell culture apparatus |
GB9116036D0 (en) * | 1991-07-25 | 1991-09-11 | Univ Leicester | Preparing grafts for implantation |
US5492826A (en) * | 1993-12-10 | 1996-02-20 | William Beaumont Hospital | Apparatus and method for seeding endothelial cells |
US5792603A (en) * | 1995-04-27 | 1998-08-11 | Advanced Tissue Sciences, Inc. | Apparatus and method for sterilizing, seeding, culturing, storing, shipping and testing tissue, synthetic or native, vascular grafts |
US6152139A (en) * | 1997-01-24 | 2000-11-28 | Heartenmedical, Inc. | Device and method for preparing veins |
-
2000
- 2000-04-14 WO PCT/EP2000/003420 patent/WO2000064569A1/en active IP Right Grant
- 2000-04-14 AU AU42958/00A patent/AU4295800A/en not_active Abandoned
- 2000-04-14 AT AT00922639T patent/ATE232137T1/en not_active IP Right Cessation
- 2000-04-14 EP EP00922639A patent/EP1173272B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO2000064569A1 (en) | 2000-11-02 |
EP1173272B1 (en) | 2003-02-05 |
ATE232137T1 (en) | 2003-02-15 |
EP1173272A1 (en) | 2002-01-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |