AU4238599A - Clear cosmetic gel composition - Google Patents
Clear cosmetic gel composition Download PDFInfo
- Publication number
- AU4238599A AU4238599A AU42385/99A AU4238599A AU4238599A AU 4238599 A AU4238599 A AU 4238599A AU 42385/99 A AU42385/99 A AU 42385/99A AU 4238599 A AU4238599 A AU 4238599A AU 4238599 A AU4238599 A AU 4238599A
- Authority
- AU
- Australia
- Prior art keywords
- composition
- clear
- antiperspirant
- gel composition
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims description 170
- 239000002537 cosmetic Substances 0.000 title claims description 38
- 239000012071 phase Substances 0.000 claims description 40
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 36
- 239000004480 active ingredient Substances 0.000 claims description 33
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 29
- 229920001296 polysiloxane Polymers 0.000 claims description 26
- 239000008346 aqueous phase Substances 0.000 claims description 24
- 239000007822 coupling agent Substances 0.000 claims description 21
- 239000012530 fluid Substances 0.000 claims description 21
- 239000004094 surface-active agent Substances 0.000 claims description 17
- 125000000217 alkyl group Chemical group 0.000 claims description 11
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 claims description 10
- 229920001451 polypropylene glycol Polymers 0.000 claims description 10
- LCZVSXRMYJUNFX-UHFFFAOYSA-N 2-[2-(2-hydroxypropoxy)propoxy]propan-1-ol Chemical compound CC(O)COC(C)COC(C)CO LCZVSXRMYJUNFX-UHFFFAOYSA-N 0.000 claims description 9
- 239000007762 w/o emulsion Substances 0.000 claims description 9
- 230000000694 effects Effects 0.000 claims description 7
- 240000007594 Oryza sativa Species 0.000 claims 1
- 235000007164 Oryza sativa Nutrition 0.000 claims 1
- 235000009566 rice Nutrition 0.000 claims 1
- 239000003213 antiperspirant Substances 0.000 description 71
- 230000001166 anti-perspirative effect Effects 0.000 description 70
- 239000000499 gel Substances 0.000 description 54
- 239000003921 oil Substances 0.000 description 33
- 239000000463 material Substances 0.000 description 31
- 235000019198 oils Nutrition 0.000 description 31
- 239000002781 deodorant agent Substances 0.000 description 24
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 21
- -1 roll-on Substances 0.000 description 21
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 19
- 239000000047 product Substances 0.000 description 19
- 239000011149 active material Substances 0.000 description 18
- 235000019441 ethanol Nutrition 0.000 description 18
- 229940008099 dimethicone Drugs 0.000 description 16
- 239000004205 dimethyl polysiloxane Substances 0.000 description 16
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 16
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 14
- 239000003349 gelling agent Substances 0.000 description 12
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 description 11
- 239000003974 emollient agent Substances 0.000 description 11
- 239000000839 emulsion Substances 0.000 description 11
- 239000004615 ingredient Substances 0.000 description 11
- 229910052782 aluminium Inorganic materials 0.000 description 9
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 9
- 229940086555 cyclomethicone Drugs 0.000 description 9
- 239000007787 solid Substances 0.000 description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 8
- 239000003205 fragrance Substances 0.000 description 8
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 7
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 7
- 239000003995 emulsifying agent Substances 0.000 description 7
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 7
- 229920001223 polyethylene glycol Polymers 0.000 description 7
- 150000003839 salts Chemical class 0.000 description 7
- 239000000600 sorbitol Substances 0.000 description 7
- LINXHFKHZLOLEI-UHFFFAOYSA-N trimethyl-[phenyl-bis(trimethylsilyloxy)silyl]oxysilane Chemical compound C[Si](C)(C)O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)C1=CC=CC=C1 LINXHFKHZLOLEI-UHFFFAOYSA-N 0.000 description 7
- 239000003795 chemical substances by application Substances 0.000 description 6
- UQEAIHBTYFGYIE-UHFFFAOYSA-N hexamethyldisiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)C UQEAIHBTYFGYIE-UHFFFAOYSA-N 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 239000002904 solvent Substances 0.000 description 6
- 206010040880 Skin irritation Diseases 0.000 description 5
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 description 5
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 description 5
- 150000001241 acetals Chemical class 0.000 description 5
- WYANSMZYIOPJFV-UHFFFAOYSA-L aluminum;2-aminoacetic acid;zirconium(4+);chloride;hydroxide;hydrate Chemical compound O.[OH-].[Al+3].[Cl-].[Zr+4].NCC(O)=O WYANSMZYIOPJFV-UHFFFAOYSA-L 0.000 description 5
- 238000001035 drying Methods 0.000 description 5
- 238000009472 formulation Methods 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 230000009467 reduction Effects 0.000 description 5
- 230000036556 skin irritation Effects 0.000 description 5
- 231100000475 skin irritation Toxicity 0.000 description 5
- 239000000344 soap Substances 0.000 description 5
- 239000001993 wax Substances 0.000 description 5
- 230000002087 whitening effect Effects 0.000 description 5
- XPFCZYUVICHKDS-UHFFFAOYSA-N 3-methylbutane-1,3-diol Chemical compound CC(C)(O)CCO XPFCZYUVICHKDS-UHFFFAOYSA-N 0.000 description 4
- QQONPFPTGQHPMA-UHFFFAOYSA-N Propene Chemical compound CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 4
- HAMGNFFXQJOFRZ-UHFFFAOYSA-L aluminum;zirconium(4+);chloride;hydroxide;hydrate Chemical compound O.[OH-].[Al+3].[Cl-].[Zr+4] HAMGNFFXQJOFRZ-UHFFFAOYSA-L 0.000 description 4
- 239000004599 antimicrobial Substances 0.000 description 4
- 125000004432 carbon atom Chemical group C* 0.000 description 4
- 239000002552 dosage form Substances 0.000 description 4
- 235000011187 glycerol Nutrition 0.000 description 4
- 229940057874 phenyl trimethicone Drugs 0.000 description 4
- 239000011148 porous material Substances 0.000 description 4
- 229960003500 triclosan Drugs 0.000 description 4
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 description 3
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- 239000004166 Lanolin Substances 0.000 description 3
- 230000002378 acidificating effect Effects 0.000 description 3
- 150000001298 alcohols Chemical class 0.000 description 3
- 229940009840 aluminum chlorhydrate Drugs 0.000 description 3
- 229940048506 aluminum zirconium tetrachlorohydrex gly Drugs 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 239000008367 deionised water Substances 0.000 description 3
- 229910021641 deionized water Inorganic materials 0.000 description 3
- 229940031578 diisopropyl adipate Drugs 0.000 description 3
- 230000007794 irritation Effects 0.000 description 3
- 229940039717 lanolin Drugs 0.000 description 3
- 235000019388 lanolin Nutrition 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 3
- 230000003287 optical effect Effects 0.000 description 3
- 239000003755 preservative agent Substances 0.000 description 3
- 241000894007 species Species 0.000 description 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 2
- ALSTYHKOOCGGFT-KTKRTIGZSA-N (9Z)-octadecen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 description 2
- FFJCNSLCJOQHKM-CLFAGFIQSA-N (z)-1-[(z)-octadec-9-enoxy]octadec-9-ene Chemical compound CCCCCCCC\C=C/CCCCCCCCOCCCCCCCC\C=C/CCCCCCCC FFJCNSLCJOQHKM-CLFAGFIQSA-N 0.000 description 2
- SFAAOBGYWOUHLU-UHFFFAOYSA-N 2-ethylhexyl hexadecanoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(CC)CCCC SFAAOBGYWOUHLU-UHFFFAOYSA-N 0.000 description 2
- WRMNZCZEMHIOCP-UHFFFAOYSA-N 2-phenylethanol Chemical compound OCCC1=CC=CC=C1 WRMNZCZEMHIOCP-UHFFFAOYSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- ZTHYODDOHIVTJV-UHFFFAOYSA-N Propyl gallate Chemical compound CCCOC(=O)C1=CC(O)=C(O)C(O)=C1 ZTHYODDOHIVTJV-UHFFFAOYSA-N 0.000 description 2
- ZGUQGPFMMTZGBQ-UHFFFAOYSA-N [Al].[Al].[Zr] Chemical compound [Al].[Al].[Zr] ZGUQGPFMMTZGBQ-UHFFFAOYSA-N 0.000 description 2
- 239000006096 absorbing agent Substances 0.000 description 2
- 230000001476 alcoholic effect Effects 0.000 description 2
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical class [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 description 2
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 description 2
- 229940053431 aluminum sesquichlorohydrate Drugs 0.000 description 2
- ALYNCZNDIQEVRV-UHFFFAOYSA-N aniline-p-carboxylic acid Natural products NC1=CC=C(C(O)=O)C=C1 ALYNCZNDIQEVRV-UHFFFAOYSA-N 0.000 description 2
- 239000003963 antioxidant agent Substances 0.000 description 2
- 235000006708 antioxidants Nutrition 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 229960001950 benzethonium chloride Drugs 0.000 description 2
- UREZNYTWGJKWBI-UHFFFAOYSA-M benzethonium chloride Chemical compound [Cl-].C1=CC(C(C)(C)CC(C)(C)C)=CC=C1OCCOCC[N+](C)(C)CC1=CC=CC=C1 UREZNYTWGJKWBI-UHFFFAOYSA-M 0.000 description 2
- SESFRYSPDFLNCH-UHFFFAOYSA-N benzyl benzoate Chemical compound C=1C=CC=CC=1C(=O)OCC1=CC=CC=C1 SESFRYSPDFLNCH-UHFFFAOYSA-N 0.000 description 2
- 239000004359 castor oil Substances 0.000 description 2
- 235000019438 castor oil Nutrition 0.000 description 2
- 239000002738 chelating agent Substances 0.000 description 2
- OSASVXMJTNOKOY-UHFFFAOYSA-N chlorobutanol Chemical compound CC(C)(O)C(Cl)(Cl)Cl OSASVXMJTNOKOY-UHFFFAOYSA-N 0.000 description 2
- 239000003086 colorant Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 239000008406 cosmetic ingredient Substances 0.000 description 2
- DOIRQSBPFJWKBE-UHFFFAOYSA-N dibutyl phthalate Chemical compound CCCCOC(=O)C1=CC=CC=C1C(=O)OCCCC DOIRQSBPFJWKBE-UHFFFAOYSA-N 0.000 description 2
- 229940031569 diisopropyl sebacate Drugs 0.000 description 2
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 2
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 2
- 239000003906 humectant Substances 0.000 description 2
- 230000000873 masking effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 description 2
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 2
- 239000002736 nonionic surfactant Substances 0.000 description 2
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 2
- 229940055577 oleyl alcohol Drugs 0.000 description 2
- XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 description 2
- PXQPEWDEAKTCGB-UHFFFAOYSA-N orotic acid Chemical compound OC(=O)C1=CC(=O)NC(=O)N1 PXQPEWDEAKTCGB-UHFFFAOYSA-N 0.000 description 2
- 235000019271 petrolatum Nutrition 0.000 description 2
- 239000002861 polymer material Substances 0.000 description 2
- RUOJZAUFBMNUDX-UHFFFAOYSA-N propylene carbonate Chemical compound CC1COC(=O)O1 RUOJZAUFBMNUDX-UHFFFAOYSA-N 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 229920002545 silicone oil Polymers 0.000 description 2
- 239000003381 stabilizer Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 150000005846 sugar alcohols Polymers 0.000 description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- JCIIKRHCWVHVFF-UHFFFAOYSA-N 1,2,4-thiadiazol-5-amine;hydrochloride Chemical compound Cl.NC1=NC=NS1 JCIIKRHCWVHVFF-UHFFFAOYSA-N 0.000 description 1
- 229940058015 1,3-butylene glycol Drugs 0.000 description 1
- SIQZJFKTROUNPI-UHFFFAOYSA-N 1-(hydroxymethyl)-5,5-dimethylhydantoin Chemical compound CC1(C)N(CO)C(=O)NC1=O SIQZJFKTROUNPI-UHFFFAOYSA-N 0.000 description 1
- DURPTKYDGMDSBL-UHFFFAOYSA-N 1-butoxybutane Chemical compound CCCCOCCCC DURPTKYDGMDSBL-UHFFFAOYSA-N 0.000 description 1
- FDCJDKXCCYFOCV-UHFFFAOYSA-N 1-hexadecoxyhexadecane Chemical compound CCCCCCCCCCCCCCCCOCCCCCCCCCCCCCCCC FDCJDKXCCYFOCV-UHFFFAOYSA-N 0.000 description 1
- HANWHVWXFQSQGJ-UHFFFAOYSA-N 1-tetradecoxytetradecane Chemical compound CCCCCCCCCCCCCCOCCCCCCCCCCCCCC HANWHVWXFQSQGJ-UHFFFAOYSA-N 0.000 description 1
- WAYINTBTZWQNSN-UHFFFAOYSA-N 11-methyldodecyl 3,5,5-trimethylhexanoate Chemical compound CC(C)CCCCCCCCCCOC(=O)CC(C)CC(C)(C)C WAYINTBTZWQNSN-UHFFFAOYSA-N 0.000 description 1
- LGEZTMRIZWCDLW-UHFFFAOYSA-N 14-methylpentadecyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCC(C)C LGEZTMRIZWCDLW-UHFFFAOYSA-N 0.000 description 1
- BDEHGQOUMOLWCN-UHFFFAOYSA-N 16-methylheptadecyl benzoate Chemical compound CC(C)CCCCCCCCCCCCCCCOC(=O)C1=CC=CC=C1 BDEHGQOUMOLWCN-UHFFFAOYSA-N 0.000 description 1
- PYJQLUORHGLSGS-UHFFFAOYSA-N 16-methylheptadecyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCCCC(C)C PYJQLUORHGLSGS-UHFFFAOYSA-N 0.000 description 1
- MEZZCSHVIGVWFI-UHFFFAOYSA-N 2,2'-Dihydroxy-4-methoxybenzophenone Chemical compound OC1=CC(OC)=CC=C1C(=O)C1=CC=CC=C1O MEZZCSHVIGVWFI-UHFFFAOYSA-N 0.000 description 1
- KMZHZAAOEWVPSE-UHFFFAOYSA-N 2,3-dihydroxypropyl acetate Chemical compound CC(=O)OCC(O)CO KMZHZAAOEWVPSE-UHFFFAOYSA-N 0.000 description 1
- DBHODFSFBXJZNY-UHFFFAOYSA-N 2,4-dichlorobenzyl alcohol Chemical compound OCC1=CC=C(Cl)C=C1Cl DBHODFSFBXJZNY-UHFFFAOYSA-N 0.000 description 1
- PWVUXRBUUYZMKM-UHFFFAOYSA-N 2-(2-hydroxyethoxy)ethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCOCCO PWVUXRBUUYZMKM-UHFFFAOYSA-N 0.000 description 1
- OMYIVFONOMOFEY-UHFFFAOYSA-N 2-(2-hydroxypropoxy)propan-1-ol;2-[2-(2-hydroxypropoxy)propoxy]propan-1-ol Chemical compound CC(O)COC(C)CO.CC(O)COC(C)COC(C)CO OMYIVFONOMOFEY-UHFFFAOYSA-N 0.000 description 1
- PFWIWMLKQFKGJD-KVVVOXFISA-N 2-[2-(2-hydroxyethoxy)ethoxy]ethanol;(z)-octadec-9-enoic acid Chemical compound OCCOCCOCCO.CCCCCCCC\C=C/CCCCCCCC(O)=O PFWIWMLKQFKGJD-KVVVOXFISA-N 0.000 description 1
- PWQNOLAKMCLNJI-KTKRTIGZSA-N 2-[2-[2-[(z)-octadec-9-enoxy]ethoxy]ethoxy]ethyl dihydrogen phosphate Chemical compound CCCCCCCC\C=C/CCCCCCCCOCCOCCOCCOP(O)(O)=O PWQNOLAKMCLNJI-KTKRTIGZSA-N 0.000 description 1
- URDCARMUOSMFFI-UHFFFAOYSA-N 2-[2-[bis(carboxymethyl)amino]ethyl-(2-hydroxyethyl)amino]acetic acid Chemical compound OCCN(CC(O)=O)CCN(CC(O)=O)CC(O)=O URDCARMUOSMFFI-UHFFFAOYSA-N 0.000 description 1
- NTRKEYLXTPNPIY-UHFFFAOYSA-N 2-[4-(diethylamino)phenyl]-3-hydroxychromen-4-one Chemical compound C1=CC(N(CC)CC)=CC=C1C1=C(O)C(=O)C2=CC=CC=C2O1 NTRKEYLXTPNPIY-UHFFFAOYSA-N 0.000 description 1
- NLXHBRUBUBDMPU-UHFFFAOYSA-N 2-ethoxyethanol;2-(2-ethoxyethoxy)ethanol;methanol Chemical compound OC.CCOCCO.CCOCCOCCO NLXHBRUBUBDMPU-UHFFFAOYSA-N 0.000 description 1
- OPJWPPVYCOPDCM-UHFFFAOYSA-N 2-ethylhexyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(CC)CCCC OPJWPPVYCOPDCM-UHFFFAOYSA-N 0.000 description 1
- HMKKFLSUPRUBOO-IUPFWZBJSA-N 3,4-dihydroxy-5-[3,4,5-tris[[(z)-octadec-9-enoyl]oxy]benzoyl]oxybenzoic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC1=C(OC(=O)CCCCCCC\C=C/CCCCCCCC)C(OC(=O)CCCCCCC\C=C/CCCCCCCC)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(O)=O)O)=C1 HMKKFLSUPRUBOO-IUPFWZBJSA-N 0.000 description 1
- UIVPNOBLHXUKDX-UHFFFAOYSA-N 3,5,5-trimethylhexyl 3,5,5-trimethylhexanoate Chemical compound CC(C)(C)CC(C)CCOC(=O)CC(C)CC(C)(C)C UIVPNOBLHXUKDX-UHFFFAOYSA-N 0.000 description 1
- RMTFNDVZYPHUEF-XZBKPIIZSA-N 3-O-methyl-D-glucose Chemical compound O=C[C@H](O)[C@@H](OC)[C@H](O)[C@H](O)CO RMTFNDVZYPHUEF-XZBKPIIZSA-N 0.000 description 1
- HBTAOSGHCXUEKI-UHFFFAOYSA-N 4-chloro-n,n-dimethyl-3-nitrobenzenesulfonamide Chemical compound CN(C)S(=O)(=O)C1=CC=C(Cl)C([N+]([O-])=O)=C1 HBTAOSGHCXUEKI-UHFFFAOYSA-N 0.000 description 1
- IIYCIBAHRPGRRX-UHFFFAOYSA-N 4-methyl-1,3-dioxolan-2-one;propane-1,2,3-triol Chemical compound OCC(O)CO.CC1COC(=O)O1 IIYCIBAHRPGRRX-UHFFFAOYSA-N 0.000 description 1
- 229940100484 5-chloro-2-methyl-4-isothiazolin-3-one Drugs 0.000 description 1
- AMEMLELAMQEAIA-UHFFFAOYSA-N 6-(tert-butyl)thieno[3,2-d]pyrimidin-4(3H)-one Chemical compound N1C=NC(=O)C2=C1C=C(C(C)(C)C)S2 AMEMLELAMQEAIA-UHFFFAOYSA-N 0.000 description 1
- BRORPGSJXSLXKN-UHFFFAOYSA-N 6-methylheptyl 3,5,5-trimethylhexanoate Chemical compound CC(C)CCCCCOC(=O)CC(C)CC(C)(C)C BRORPGSJXSLXKN-UHFFFAOYSA-N 0.000 description 1
- 229910018580 Al—Zr Inorganic materials 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- MOZDKDIOPSPTBH-UHFFFAOYSA-N Benzyl parahydroxybenzoate Chemical compound C1=CC(O)=CC=C1C(=O)OCC1=CC=CC=C1 MOZDKDIOPSPTBH-UHFFFAOYSA-N 0.000 description 1
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- 239000004292 methyl p-hydroxybenzoate Substances 0.000 description 1
- 229960001047 methyl salicylate Drugs 0.000 description 1
- 229960002285 methylbenzethonium chloride Drugs 0.000 description 1
- 229960002216 methylparaben Drugs 0.000 description 1
- 239000004530 micro-emulsion Substances 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 239000001788 mono and diglycerides of fatty acids Substances 0.000 description 1
- 229940094510 myristalkonium chloride Drugs 0.000 description 1
- VGJHYDGTJKYGLB-UHFFFAOYSA-N n-(2-methoxyphenyl)-3,4-dihydro-2h-quinoline-1-carboxamide Chemical compound COC1=CC=CC=C1NC(=O)N1C2=CC=CC=C2CCC1 VGJHYDGTJKYGLB-UHFFFAOYSA-N 0.000 description 1
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- QFOHBWFCKVYLES-UHFFFAOYSA-N n-butyl para-hydroxybenzoate Natural products CCCCOC(=O)C1=CC=C(O)C=C1 QFOHBWFCKVYLES-UHFFFAOYSA-N 0.000 description 1
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 150000002823 nitrates Chemical class 0.000 description 1
- 239000007764 o/w emulsion Substances 0.000 description 1
- NKBWPOSQERPBFI-UHFFFAOYSA-N octadecyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCCOC(=O)CCCCCCCCCCCCCCCCC NKBWPOSQERPBFI-UHFFFAOYSA-N 0.000 description 1
- YPMOZWCBANATQH-UHFFFAOYSA-N octyl 7-methyloctanoate Chemical compound CCCCCCCCOC(=O)CCCCCC(C)C YPMOZWCBANATQH-UHFFFAOYSA-N 0.000 description 1
- 229940049964 oleate Drugs 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 229960005010 orotic acid Drugs 0.000 description 1
- LLEMOWNGBBNAJR-UHFFFAOYSA-N ortho-phenyl-phenol Natural products OC1=CC=CC=C1C1=CC=CC=C1 LLEMOWNGBBNAJR-UHFFFAOYSA-N 0.000 description 1
- 235000010292 orthophenyl phenol Nutrition 0.000 description 1
- LXTZRIBXKVRLOA-UHFFFAOYSA-N padimate a Chemical compound CCCCCOC(=O)C1=CC=C(N(C)C)C=C1 LXTZRIBXKVRLOA-UHFFFAOYSA-N 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 235000019809 paraffin wax Nutrition 0.000 description 1
- 229920002866 paraformaldehyde Polymers 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- PNSWKXISZRTMSD-UHFFFAOYSA-K pentasodium;phosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[Na+].[O-]P([O-])([O-])=O PNSWKXISZRTMSD-UHFFFAOYSA-K 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 229940066842 petrolatum Drugs 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940096826 phenylmercuric acetate Drugs 0.000 description 1
- NFIYTPYOYDDLGO-UHFFFAOYSA-N phosphoric acid;sodium Chemical compound [Na].OP(O)(O)=O NFIYTPYOYDDLGO-UHFFFAOYSA-N 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 1
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 229940050271 potassium alum Drugs 0.000 description 1
- GRLPQNLYRHEGIJ-UHFFFAOYSA-J potassium aluminium sulfate Chemical compound [Al+3].[K+].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O GRLPQNLYRHEGIJ-UHFFFAOYSA-J 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- XEIOPEQGDSYOIH-MURFETPASA-N propan-2-yl (9z,12z)-octadeca-9,12-dienoate Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(=O)OC(C)C XEIOPEQGDSYOIH-MURFETPASA-N 0.000 description 1
- NEOZOXKVMDBOSG-UHFFFAOYSA-N propan-2-yl 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OC(C)C NEOZOXKVMDBOSG-UHFFFAOYSA-N 0.000 description 1
- VYCBIUQCKXHYSM-UHFFFAOYSA-N propane-1,2,3-triol;urea Chemical compound NC(N)=O.OCC(O)CO VYCBIUQCKXHYSM-UHFFFAOYSA-N 0.000 description 1
- 239000000473 propyl gallate Substances 0.000 description 1
- 235000010388 propyl gallate Nutrition 0.000 description 1
- 229940075579 propyl gallate Drugs 0.000 description 1
- 229960005359 propylparaben sodium Drugs 0.000 description 1
- 235000019259 sodium dehydroacetate Nutrition 0.000 description 1
- 235000010268 sodium methyl p-hydroxybenzoate Nutrition 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- PESXGULMKCKJCC-UHFFFAOYSA-M sodium;4-methoxycarbonylphenolate Chemical compound [Na+].COC(=O)C1=CC=C([O-])C=C1 PESXGULMKCKJCC-UHFFFAOYSA-M 0.000 description 1
- IXMINYBUNCWGER-UHFFFAOYSA-M sodium;4-propoxycarbonylphenolate Chemical compound [Na+].CCCOC(=O)C1=CC=C([O-])C=C1 IXMINYBUNCWGER-UHFFFAOYSA-M 0.000 description 1
- CRPCXAMJWCDHFM-UHFFFAOYSA-M sodium;5-oxopyrrolidine-2-carboxylate Chemical compound [Na+].[O-]C(=O)C1CCC(=O)N1 CRPCXAMJWCDHFM-UHFFFAOYSA-M 0.000 description 1
- 239000012265 solid product Substances 0.000 description 1
- 230000007928 solubilization Effects 0.000 description 1
- 238000005063 solubilization Methods 0.000 description 1
- 238000000935 solvent evaporation Methods 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
- 239000004334 sorbic acid Substances 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- 229950011392 sorbitan stearate Drugs 0.000 description 1
- 235000015096 spirit Nutrition 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 229940057981 stearalkonium chloride Drugs 0.000 description 1
- SFVFIFLLYFPGHH-UHFFFAOYSA-M stearalkonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 SFVFIFLLYFPGHH-UHFFFAOYSA-M 0.000 description 1
- CXVGEDCSTKKODG-UHFFFAOYSA-N sulisobenzone Chemical compound C1=C(S(O)(=O)=O)C(OC)=CC(O)=C1C(=O)C1=CC=CC=C1 CXVGEDCSTKKODG-UHFFFAOYSA-N 0.000 description 1
- 229960000368 sulisobenzone Drugs 0.000 description 1
- 230000000475 sunscreen effect Effects 0.000 description 1
- 239000000516 sunscreening agent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000003760 tallow Substances 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- WWSBQOYADFGDQE-UHFFFAOYSA-N tridecanedioic acid dimethyl ester Natural products COC(=O)CCCCCCCCCCCC(=O)OC WWSBQOYADFGDQE-UHFFFAOYSA-N 0.000 description 1
- KMZJRCPGGAQHGC-UHFFFAOYSA-N trisodium boric acid borate Chemical compound [Na+].[Na+].[Na+].OB(O)O.[O-]B([O-])[O-] KMZJRCPGGAQHGC-UHFFFAOYSA-N 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- PICXIOQBANWBIZ-UHFFFAOYSA-N zinc;1-oxidopyridine-2-thione Chemical compound [Zn+2].[O-]N1C=CC=CC1=S.[O-]N1C=CC=CC1=S PICXIOQBANWBIZ-UHFFFAOYSA-N 0.000 description 1
- 229910052726 zirconium Inorganic materials 0.000 description 1
Description
AUSTRALIA
Patents Act 1990 Colgate-Palmolive Company
ORIGINAL
COMPLETE SPECIFICATION STANDARD PATENT Invention Title: Clear cosmetic gel composition The following statement is a full description of this invention including the best method of performing it known to us:o r r
A
Description Clear Cosmetic Gel Composition Technical Field The present invention is directed to a clear cosmetic gel composition (for example, a clear soft gel antiperspirant composition) that is a water-in-oil emulsion. The composition of the present invention can include deodorant and/or antiperspirant active materials, to combat body malodor, for example, in axillary regions of the human body, by applying the composition to the human body (for example, to the skin, in axillary regions of the body).
The present invention is particularly directed to cosmetic gel compositions, including antiperspirant and deodorant gel compositions, that have reduced whitening and tack, and reduced skin irritation, and which can include increased amounts of the cosmetically active ingredient (for example, 20 increased amounts of antiperspirant active ingredient), and can include other commercially beneficial materials, yet which can be provided as a clear gel product.
Background Art Antiperspirant products are well known in the art. Antiperspirants have appeared in the marketplace in varied dosage forms, such as sticks, soft solids, soft gels, roll-on, aerosols and creams. Generally, these dosage forms include a solution of the active ingredient in a suitable solvent, a suspension of the active ingredient in a non-solvent, or a multiphasic dispersion or emulsion in which a solution of the active ingredient is dispersed in some continuous phase or in which the solubilized active ingredient constitutes a continuous phase.
Of the above-referred-to dosage forms, the stick form is an example of a solid form, and the soft solid and soft gel are thickened forms which may or may not be solid (for example, under some circumstances, gels can flow). The stick form can be distinguished from a soft solid or soft gel in that, in a stick, the formulated product can retain its shape for extended time periods outside the package, the product not loosing its shape significantly (allowing for some shrinkage due to solvent evaporation). Adjustment of amounts of gelling or thickening agents can be used in order to form a soft gel or stick.
Soft gels or soft solids can be suitably packaged in containers which have the appearance of a stick, but which dispense through apertures (for 20 example, slots or pores) on the top surface of the S"package. The soft solid products have also been n eenfe called soft sticks or "smooth-ons", and hereinafter are generically called "soft solids". Reference is made to U.S. Patent No. 5,102,656 to Kasat, No. 5,069,897 to Orr, and No. 4,937,069 to Shin, each of which discloses such soft solids, including physical characteristics thereof such as viscosity and hardness. The contents of each of these three U.S. Patents are incorporated herein by reference in 30 their entirety.
Recently, there has been significant activity in developing clear and translucent antiperspirant sticks and soft gels, particularly to provide sticks and soft gels having increased efficacy (for example, by providing increased amounts of the antiperspirant active in the sticks and soft gels), improved cosmetic characteristics (including reduced whitening, reduced residue and reduced tack), and reduced skin irritation potential providing a product that is "mild") Clear or translucent antiperspirant sticks consisting essentially of a solution of the active antiperspirant material in a polyhydric alcohol vehicle, gelled by dibenzylidene monosorbitol acetal, have been disclosed. Since the gelling agent is inherently unstable in an acidic environment, and since conventional active antiperspirant materials are acidic, much work has been involved in discovering suitable stabilizing or buffering agents to prevent or slow down acid attack on the acetal gelling agent. Such work has not been completely successful. Moreover, these clear or translucent antiperspirant sticks, containing the acetal gelling agent and including a solubilized active antiperspirant material, have the disadvantage of being inherently tacky. Thus, development work in connection with these clear or translucent antiperspirant sticks containing the acetal gelling 25 agent has focused on discovering suitable anti-tack agents for this dosage form. However, since acid hydrolysis of the gelling agent occurs more rapidly in aqueous solutions, formulators have been forced to avoid using water in the formulations. This severely restricts the ability of the formulator to develop cosmetically elegant formulations which are simultaneously chemically stable, optically clear, low in tack, low in residue and which have acceptable application aesthetics.
Various other gelling agents have been utilized in antiperspirant and deodorant products. For example, clear stick deodorant compositions have been available for some time. The clear deodorant sticks are generally produced by using stearate soaps as gelling agents for an alcoholic or glycolic solution of an antimicrobial agent and a fragrance.
These deodorant products offer no antiperspirant protection (that is, these deodorant products do not reduce flow of perspiration from a human).
Conventional antiperspirant active ingredients, which are acidic, are not ordinarily used with stearate soap gelling agents, because they are incompatible with the stearate soap gelling agents, due to the chemical interaction between the antiperspirant active material and the soap and consequent inactivation of the antiperspirant active material.
Gelling, for cosmetic compositions, may also be 20 achieved through the use of cellulosic or algin-derived polymer materials. Most of these materials are incompatible with conventional antiperspirant active ingredients, at levels of the antiperspirant active ingredients required to obtain antiperspirant efficacy. Moreover, the polymer materials are unstable at the low pH normally encountered in antiperspirant products.
Concerning wax and soap-gelled sticks, see each of U.S. Patent No. 4,382,079 to Marschner, No. 4,414,200 to Murphy, et al., No. 4,280,994 to Turney, No. 4,265,878 to Keil, No. 3,259,545 to Teller, No. 2,970,083 to Bell, No. 2,933,433 to Teller, et al., No. 2,900,306 to Slater, No. 2,857,315 to Teller, and No. 4,383,988 to Teng.
U.S. Patent No. 4,948,578 to Burger, et al discloses a transparent antiperspirant stick which is an oil-in-water emulsion, containing specific amounts of an antiperspirant effective aluminum salt, a nonionic surfactant which is a fatty alcohol alkoxylated with from about 10 to about moles ethylene oxide, a liquid oil immiscible with water, and water, the composition being free of any wax matrix. Illustratively, aluminum chlorhydrate is the antiperspirant salt, the nonionic surfactant is a alcohol ethoxylate, and the liquid oil component may be selected from emollient oils, volatile silicones and mixtures of these materials.
U.S. Patent No. 4,944,938 to Potini discloses clear, non-alcoholic, quick drying, antiperspirant and deodorant gels, which are stable both at room temperatures and at higher temperatures, are non-stinging and leave no white residue on the skin, Sthe gel not including gelling agents, waxes, clays, or monohydric alcohols having 2-8 carbon atoms. The gels use 3-5 carbon atom trihydric alcohols as coupling agents, these alcohols acting as solublizers in the system and keeping the system stable and clear. The gels can include an 2: 5 aluminum active salt; a volatile water-insoluble emollient, such as isostearyl benzoate; a soluble emollient such as cetyl ether; solubilizers such as ropylene glycol and glycerine; volatile siloxanes; and water.
30 Some cellulosic materials, such as hydroxypropylcelluouse, among others, are compatible with polyvalent metal salts and have been used in the manufacture of clear lotions. These cellulosic materials, however, must be prepared with a high percentage of water or alcohol in order to insure solubilization of the active ingredient. The resulting formulations, in addition to a high irritation potential, are tacky and pituitous, and low in efficacy, when alcohol-based; and exhibit tackiness and a long drying time when water-based.
Clear or translucent antiperspirant soft gels (which have been dispensed from containers having the appearance of stick) have recently been marketed, consisting of viscous high-internal-phase emulsions. These soft gels exhibit some advantages over the aforementioned sticks, particularly acetal-based clear sticks, in that the selection of formulation ingredients is less restricted (for example, water can be used), and often tack can be reduced significantly. Concerning these emulsions, note U.S. Patent No. 4,673,570 to Soldati and No. 4,900,542 to Parrotta, et al. These two U.S.
20 patents disclose clear gelled antiperspirant compositions free of waxes and conventional gelling agents, containing a volatile silicone fluid, a silicone emulsifier, a destablizing auxiliary :emulsifier, water, non-volatile emollient, a coupling agent, an active antiperspirant component and ancillary agents such as perfume, coloring agents, etc. The silicone emulsifier is a cyclomethicone-dimethicone copolyol silicone fluid marketed by Dow Corning Corp. under the trademark DOW CORNING 3225C formulation. The contents of these two U.S. patents are incorporated herein by reference in their entirety.
Also to be noted is PCT (International application) Publication No. WO 92/05767. This patent document discloses a clear gel-type cosmetic producz; having a viscositY Of at leas,: 50,000 cps at 2ICand a refract.ve indexc of 1.3975-.05a and having an. optical clarity *ecter than 50 NTTJ (Nephelornecr~c Turbidity Units) at 210C, =he product bein.- an emulsicn with a water phase having an active ingredient incorporated therein and With an. oLIl. phase. The refractive indices (measured at 5393A.) of the water and oil phases riatch to within 0.0004. The oil phase includes an, emulsifier which when properly mixed with t:he water phase ionrenz yields a water-in-oil e-mulsion, and the water phase includes on~e or a combination of various polar species suhas water, propylene glycol, sorbitol and ethanol. The water phase includes che deodozranr and/or antiperspi.rant active ingredient.
Th1,e contents of t'his PCT (International appli4cation;, Publication NTo. 92/05T7" are incco-crated herein. reference in their- entirety.
.European Patent specif-4 a-:-on Pt,%bIicatiorn No.
0 373 499 BI to Pc dn~cescrib'es a clear no-a1coi.c, a quick drying, highly active, anz:Jpersp4-ant and a. .deodorant gel. The compositions ccmp-rise volatile Siloxanes and Sa sco lvh'pdri= a_-cohols as solubilizers.
PCT (:nterna:.o-nal applicatiofl) Publicati.on No.
91/08732 to Kwass describes an optically clear 116qid antinerspiranz roll-on product in the form of a stable *a...water-in-oil1 emulsion. Examples of stabilizing agents &wee -ancl,.de a. polyalkox)ylated alcohol and a lower alcohol aahaving a molecular weight less than the p-olyaikoxyl'ated While variou5 Cosrnet.-c gel cczpositicns, including ancipers-Pirant and deodoranc comPcSi:.cnls, ,:hat are clear, are knc',n. it is still desired tc Provide a clear co:smetic gel conposition clear antiperspirant and/or deodorant gel composition) having an increased amount of cosmetically active material antiperspirant agent) and also having other materials providing advantageous cosmetic effects in the composition, while maintaining a clear composition; having reduced whitening and tack; and which is mild and has reduced skin irritation potential relative to commercially available products.
Disclosure of the Invention: The present invention provides a clear and mild cosmetic gel composition including: an aqueous phase containing water, (ii) at least one cosmetically active ingredient in an amount sufficient to have a cosmetic effect; and (iii) at least one polypropylene glycol; an oil phase; at least one coupling agent such that the aqueous phase is *uniformly distributed in the oil phase; an alkoxylated, alkyl substituted siloxane surface active agent in an amount so as to form a water-in-oil emulsion; wherein the cosmetic gel composition is a water-in-oil emulsion.
In a preferred embodiment, the present invention provides a clear and mild cosmetic gel composition wherein the at least one polypropylene glycol includes tripropylene glycol. Furthermore, in another preferred embodiment the clear and mild cosmetic gel composition includes propylene glycol in the aqueous.
In yet another preferred embodiment, the present invention provides a clear and mild cosmetic gel composition wherein the oil phase includes silicone fluids.
Accordingly, by the present invention, a clear cosmetic gel composition (for example, a clear antiperspirant gel composition, such as a clear antiperspirant soft gel composition) can be provided, having increased amounts of cosmetically active ingredients (such as antiperspirant active material) and having other high refractive index beneficial materials in the composition while maintaining clarity of the composition. The composition is easy to manufacture. The composition has improved tack, a cool sensation, a silky feel and imparts no white residue on dry down compared to commercially available products. Moreover, compositions of the present invention incorporating a polypropylene glycol component (especially tripropylene glycol) have improved mildness (have reduced skin irritation potential) as compared to commercially available products, and have improved cosmetic properties (including reduced tackiness) and reduced white residue upon application.
Throughout this specification, the word "comprise", or variations such as "comprises" or "comprising", will be understood to imply the inclusion of a stated element, integer or step, or group of elements, integers or steps, but not the exclusion of any other element, integer or step, or group of elements, integers or steps.
Best Mode for Carrying Out the Invention 20 While the invention will be described in connection with specific and ~preferred embodiments it will be understood that it is not intended to limit .the invention to those embodiments. To the contrary, it is intended to cover all alterations, modifications and equivalents as may be included within the spirit and scope of the invention as defined by the appended claims.
Throughout the present disclosure, the present invention is described primarily in connection with a clear soft gel antiperspirant composition.
However, the present invention is not limited to soft gel compositions or to antiperspirant compositions. For example, compositions according to the present invention can be clear deodorant compositions. Moreover, depending on additional or other active ingredients included in the composition, the composition can also be an emollient composition, an analgesic (methyl salicylate) composition, a sunscreen composition, etc.
Various active materials incorporated in cosmetic compositions are disclosed in U.S. Patent 5* 9
S
S ft
S
20 CC C
S
5@ 2
S.
S...3 No. 4,322,400 to Yuhas, the contents of which are incorporated herein by reference in their entirety.
Throughout the present specification, "active antiperspirant" and "active deodorant" materials are discussed. Both types of materials contribute to reduction of body axillary) malodor. By reduction of body malodor, we mean that, generally, there is less body malodor after application of a composition to the person's skin as compared to the person's body malodor without application of the composition. Such reduction can be due to a masking of the malodor, absorption and/or chemical reaction of the malodorous material, reduction of levels of the bacteria producing the malodorous material, from perspiration, reduction of perspiration, etc. The antiperspirant active materials, when utilized in an antiperspirant effective amount in the composition, act to reduce body malodor by reducing production of perspiration; however, these antiperspirant active materials can also have a deodorant function, as an antimicrobial agent.
The deodorant active materials do not substantiall.
reduce the production of perspiration, but reduce malodor in other ways, as fragrances masking the malodor or reducing the malodor intensity, as odor absorbents, as antimicrobial agents, as agents chemically reacted with malodorous materials, etc.
Throughout the present specification, where compositions are described as including or comprising specific components or materials, it is contemplated by the inventors that the compositions of the present invention also consist essentially of, or consist of, the recited components or materials. Accordingly, throughout the present disclosure any described composition of the present invention can consist essentially of, or consist o:, the recited components or materials.
A desired feature of the present invention is that a clear, or transparent, cosmetic gel composition clear or transparent deodorant or antiperspirant gel composition) can be provided.
The term clear or transparent (that is clarity), according to the present invention, is intended to connote its usual dictionary definition; thus, a clear, cosmetic gel composition of the present invention allows ready viewing of objects behind it.
By contrast, a translucent composition allows light to pass through, but causes the light to be so scattered that it will be impossible to see clearly objects behind the translucent composition. Optical clarity of compositions of the present invention can be measured using a turbidimeter, and desirably is better than 50 NTU measured at room temperature 0 -25 0
C).
The present invention contemplates a clear cosmetic gel composition which is a water-in-oil emulsion. The aqueous phase of this emulsion contains water and at least one cosmetically active ingredient, with the cosmetically active ingredient being in the composition in an amount so as to have a cosmetic effect. The oil phase of the emulsion includes a high refractive index material (a material having a refractive index in the range of 1.40-1.50), and desirably also includes silicone fluids, and preferably contains both volatile and non-volatile silicone fluids. The compositions according to the present invention also include at least one coupling agent to bring the aqueous phase and the oil phase into a homogeneous composition, and an alkoxylated, alkyl substituted siloxane surface active agent to provide a water-in-oil emulsion. According to this aspect of the present invention, the composition has a refractive index in a range from about 1.4026 to 1.4150. This range for the refractive index is higher than the maximum of the range described in PCT International Application Publication No. WO 92/05767. By utilizing a higher refractive index, in a range as disclosed in the 0 present application, clarity of the composition can be maintained, while increased amounts of cosmetic active ingredient antiperspirant active ingredient such as an antiperspirant aluminum-containing salt) can be incorporated in the composition; and high refractive index materials providing advantageous benefits to the composition can be incorporated in the aqueous and oil phases of the composition.
The material, incorporated in the oil phase, which has the high refractive index, desirably is an emollient, and preferably has a refractive index in the range of 1.43 to 1.47, most preferably 1.45 to 1.47.
Desirably, refractive indices of the mixture of aqueous phase and at least one coupling agent, on the one hand, and the mixture of the oil phase and alkoxylated, alkyl substituted siloxane surface active agent, on the other, match each other to within 0.0005; that is, a difference between (1) 30 the refractive index of the mixture of aqueous phase and coupling agents and the refractive index of the mixture of oil phase and alkoxylated, alkyl substituted siloxane surface active agent, is less than 0.0005.
;I
An optically clear cosmetic antiperspirant or deodorant) gel composition that is visually clear, and, like glass, allows for the viewing of the objects behind it, is achieved. In particular, a composition having an optical clarity better than 50 NTU at room temperature (20 0 -25 0
C),
preferably having a turbidity measurement less than NTU, more preferably less than 20 NTU, can be achieved.
Moreover, the clear cosmetic gel composition of the present invention, which is in the form of a macro-emulsion as contrasted to a micro-emulsion, does not need to contain wax or gelling agents such as soaps, cellulosic materials or algenites.
Furthermore, the composition according to the present invention does not require polydimethylcyclosiloxane, although the present compositions may contain this material.
The gel emulsions according to the present invention are stable and optically clear, are cosmetically elegant, and are capable of being delivered from a suitable applicator package. They are easily applied to the skin and have a smooth, silky feel and a cool sensation, yet are fast-drying 25 and non-tacky. These compositions of the present invention may be prepared by a batch process, or a continuous or semi-continuous process, and the .i processes yield compositions which are stable, highly efficacious and possess excellent aesthetic qualities.
Where the composition is an antiperspirant gel composition, any of the known antiperspirant active materials can be utilized in the composition of the present invention. Suitable materials which may be mentioned by way of example include aluminum chlorhydrate, aluminum chloride, aluminum sesquichlorohydrate, aluminum-zirconium hydroxychlorides, complexes or adducts of the above-mentioned active ingredients with glycol, such as propylene glycol (for example, "Rehydrol" II from Reheis Chemical and combinations thereof.
Known aluminum-zirconium salts in combination with neutral amino acids, such as glycine aluminum-zirconium tetrachlorohydrex Gly) can also be used. Generally, any of the Category I active antiperspirant ingredients, listed in the Food and Drug Administration's Monograph on Antiperspirant Drug Products for overall-the-counter human use (October 10, 1973) can be used. In addition, any new ingredient, not listed in the Monograph, such as aluminum nitratohydrate and its combination with zirconyl hydroxychlorides and nitrates, or aluminum-stannous chlorohydrates, can be incorporated as an antiperspirant active ingredient in antiperspirant compositions according to the present invention.
Antiperspirant active materials can be, but are not limited to, the following: Antiperspirant Actives Astringent salt of aluminum Astringent salt of zirconium Aluminum bromohydrate Aluminum chlorohydrate 30 Aluminum dichlorohydrate Aluminum sesquichlorohydrate SAluminum chlorohydrex
PG
Aluminum dichlorohydrex
PG
Aluminum sesquichlorohydrex PG 35 Aluminum chlorohydrex
PEG
3 Aluminum dichlorohydrex
PEG
Aluminum sesquichlorohydrex
PEG
Aluminum chloride Aluminum sulfate Aluminum zirconium chlorohydrate Aluminum zirconium trichlorohydrate Aluminum zirconium tetrachlorohydrate Aluminum zirconium pentachlorohydrate Aluminum zirconium octachlorohydrate Aluminum zirconium trichlorohydrex Gly Aluminum zirconium tetrachlorohydrex Gly Aluminum zirconium pentachlorohydrex Gly Aluminum zirconium octachlorohydrex Gly Buffered aluminum sulfate Potassium alum Sodium aluminum chlorohydroxy lactate The preferred antiperspirant materials include Rezal 36G, aluminum zirconium tetrachlorohydrate or aluminum chlorhydrate.
The amount of active component that can be used will vary with the particular active ingredient incorporated. As a general rule, an antiperspirant product should contain an active antiperspirant material in an amount anywhere from about 10% to about 35% by weight, of the total weight of the composition, more preferably from about 20% to about by weight, of the total weight of the composition. The active antiperspirant material utilized in the compositions of the present invention can be pre-dissolved in water or in another solvent (for example, in propylene glycol), or can be in powdered form, and may be buffered or unbuffered. Preferably, the antiperspirant 30 materials are present in solution in a solvent therefor.
Where a deodorant active material is utilized, any deodorant active material which can be dissolved in the aqueous phase can be utilized.
Illustratively, the deodorant active material can be 2, 4, 4'-trichloro-2'-hydroxy diphenyl ether I ac (triclosan), and/or benzethonium chloride. Where 17 the deodorant ingredient is used in place of the antiperspirant active ingredient, a deodorant gel composition (rather than an antiperspirant gel composition) would be provided.
Amounts of cosmetically active ingredients incorporated are those sufficient to have a cosmetic effect. For example, where a deodorant active ingredient such as triclosan is incorporated, amounts thereof as conventionally used in the art can be incorporated in the composition according to the present invention.
The aqueous phase includes one or a combination of various polar species, and includes at least water (refractive index of 1.3333). Other polar species include polyhydric alcohols and derivatives thereof esters and ethers thereof).
Illustratively, water can be included in the composition in an amount in the range of 20% to by weight, of the total weight of the composition.
At least one coupling agent is included in tne composition of the present invention. Such couDlina agent is illustratively (but not limited to) the following: Ethyl alcohol 25 2 -ethylhexanol Ethylene carbonate N-methylglucamine Linear ethoxylated polymer of methanol Ethylene glycol monoethyl ether Diethylene glycol monoethyl ether Propoxylated oleyl alcohol Butyl stearate Butyl myristate Isopropyl alcohol 5 SD-40 alcohol Mineral Spirits "*PPG myristyl ether PPG 2-8) lauryl ether Dipropylene glycol 40 Sorbitol PPG (2-10) cetyl ether PEG-6 diisopropyl adipate Methoxy PEG-22 dodecyl-glycol copolymer Glyceryl monoacetate sorbitol PEG-3 oleyl ether phosphate oleyl ether lanolate PPG-(2-8) isostearate Propylene glycol methyl ether PPG-(2-3) methyl ether PPG-14 butyl ether Ethoxylated (2-20 moles) glucose Propoxylated (2-20 moles) glucose Stearyl ether PPG-(5-20) methyl glucose ether Isoprene glycol Propylene carbonate Glycerine This coupling agent acts to stabilize the emulsion and also acts as a clarifying agent.
Moreover, various of these coupling agents, such as alcohol, aid in drying and has a cooling effect, providing advantageous aesthetic properties for the composition.
The coupling agent is preferably a low molecular weight alcohol such as, but not limited to, an alcohol having from about 2 to about carbon atoms, preferably from about 2 to about 4 carbon atoms; or a glycol such as, but not limited 30 to, propylene glycol, ethylene glycol, isoprene glycol and dipropylene glycol; glycerine, sorbitol and/or propylene carbonate. The coupling agent can be one compound or a mixture of compounds.
Illustratively, the coupling agent is present in an amount of from about 10% to about 30% by weight, preferably from about 14% to about 25% by weight, of the total weight of the composition.
S. o S S
S
r~er 2 25 o The oil phase according to the present invention is, desirably, a silicone oil phase, so as to provide a water-in-silicone oil emulsion. The total of oil phase and siloxane surface active agent preferably makes up from about 8% to about 30% by weight, of the total weight of the composition.
This surface active agent is an emulsifier which, when properly mixed with the aqueous phase components, oil phase components and coupling agents, yields a water-in-oil emulsion. The oil phase is desirably a blend of liquids.
The oil phase can include, illustratively, a volatile silicone fluid such as cyclomethicone and a non-volatile silicone fluid such as dimethicone; however, the composition of the present invention need not include both the volatile and non-volatile silicone fluids. Where the composition includes the volatile silicone, it is preferred that such volatile silicone be a polydimethylcyclosiloxane, present in an amount up to about 18% by weight, of the total weight of the composition, preferably from about 4% to about 12% by weight, of the total weight of the composition. Preferred polydimethylcyclosiloxanes are those named cyclomethicones, exemplified by the formula ((CH3) 2 SiO), where x is a number from about 4 to about 6. Preferred cyclosiloxanes are cctamethylcyclotetrasiloxane decamethylcyclopentasiloxane and blends of tetramer and pentamer cyclomethicones. Commercial cyclosiloxanes which can be utilized as part of the composition of the present invention include, illustratively, Dow Corning 244 fluid, Dow Corning 245 fluid, Dow Corning 344 fluid and Dow Corning 345 fluid (from Dow Corning Corp.).
5 S S .5.5 5**5
S
S S
S
The oil phase preferably is a mixture of a volatile silicone fluid (such as cyclomethicone), a non-volatile silicone fluid (such as dimethicone), and a high refractive index compatible emollient such as phenyl trimethicone. This high refractive index emollient has a higher refractive index than that of the silicone fluids (volatile silicone fluid and/or non-volatile silicone fluid) of the oil phase.
The alkoxylated, alkyl substituted siloxane surface active agent is preferably, but not limited to, a dimethicone copolyol. An illustrative alkoxylated silicone-containing surfactant utilizable according to the present invention is cetyl dimethicone copolyol, referred to in U.S.
Patent No. 5,162,378 to Guthauser. Illustratively, the alkoxylated, alkyl substituted siloxane surface active agent is included in t.he composition in an amount of 0.2% to 2% by weight, of the total weight of the composition.
A specific cyclomethicone-dimethicone copolyol fluid which can be utilized to provide the alkoxylated silicone containing surface active agent is a mixture of cyclomethicone and dimethicone copolyol designated as DC3225C from Dow Corning Corp. This is a polyether substituted silicone of cyclomethicone and dimethicone copolyol (refractive index (RI) 1.3994). This DC3225C, which is an emulsifying agent, is useful for preparing stable water-in-oil emulsions where a silicone makes up a large portion of the oil phase, and is a dispersion of a silicone surfactant (dimethicone copolyol) by wt.) in cyclomethicone (Dow Corning 344 Fluid) (90% by wt.).
The mixture of cyclomethicone and dimethicone copolyol fluid is present in the composition, illustratively, in an amount of from about 4% to about 20% by weight, of the total weight of the composition.
Various materials incorporated in the water-based phase and in the oil-based phase, and their refractive indices (as measured using the Bausch and Lomb Abbe 3L Refractometer), are set forth in the following: Water-based chase Ingredient RI at 21 0
C
Al-Zr Tetrachlorohydrex GLY 1.4185 (Rexal 36G (cone) 46%) SD40 Alcohol 1.3644 Butanediol 1.3644510 Propylene Glycol 1.4334 1,3-Butylene Glycol 1.4404 Dipropylene Glycol 1.4415 Propylene Carbonate 1.4216 Sorbitol 1.421605 Isoprene Glycol 1.4422 Tween 80 1.4725 Carbowax PEG 200 1.472589 Carbowax PEG 300 1.4589 SCarbowax PEG 400 1.4671 Tween 20 1.46715 1.4705 Water (Deionized) 1.3336 Glycerine 1.4743 .1.4743 Oil-based phase Ingredient RI at 21 0
C
Dimethicone (DC 200 (50cs)) 1.4049 Phenyl Trimethicone (DC 556) 1.4614 Polyisobutylene (Panalane L-14E) 1.4592 Diisopropyl adipate (Dermol DIA) 1.4248 .Polydecene (Silkflo 362NF) 1.4448 Polydecene (Silkflo 364NF) 1.455448 Polydecene (Silkflo 36NF) 1.4554 r Polydecene (Silkflo 366NF) 1.4595 Diisopropyl Sebacate (Pelemol DIPS) 1.4337 Octyl Isononanoate (Dermol 89) 1.4366 Isostearyl Stearate (Estalon ISS) Dermol G-76 DC Q2-5220 DC 3225C 1.4565 1.4988 1.4536 1.3994 The composition according to the present invention can include additional cosmetically active ingredients such as emollients, humectants, antiseptics, antioxidants, chelating agents, ultraviolet absorbers, colorants, fragrances and preservatives, as known in the art, which ingredients include, but are not limited to, the following: Emollients S*o 35 *to o*.
@060 ,000 00 *0 0 go Dt Stearyl alcohol Glyceryl monoricinoleate Glyceryl monostearate Sulphated tallow Propylene glycol Mink oil Cetyl alcohol Stearyl stearate Isopropyl isostearate Dimethyl brassylate Diisopropyl adipate n-dibutyl sebacate Diisopropyl sebacate 2-ethyl hexyl palmitate Isononyl isononanoate Isodecyl isononanoate Isotridecyl isononanoate 2-ethyl hexyl palmitate 2-ethyl hexyl stearate D-(2-ethyl hexyl) adipate) Di-(2-ethyl hexyl) succinate Isopropyl myristate Isopropyl palmitate Isopropyl stearate Stearic acid Isobutyl palmitate Isocetyl stearate Oleyl alcohol Isopropyl laurate Sorbitan Stearate Hydrogenated Castor Oil Hydrogenated soy glycerides Hexyl laurate Decyl oleate 0 500* 23 Emollients cont.
Octacosano 1 Butyl stearate Glyceryl monostearate Polyethylene glycols Oleic acid Triethylene glycol Lanolin Castor oil Acetylated lanolin alcohols Acetylated lanolin Petrolatum Isopropyl ester of lanolin fatty acids Mineral oils Butyl myristate Isostearic acid Palmitic acid PEG-23 oleyl ether Olelyl Oleate Isopropyl linoleate Cetyl lactate Lauryl lactate Myristyl lactate Quaterriised hydroxy alkyl aminogluconate Vegetable Oils Isodecyl oleate Isostearyl neopentanoate Myristyl myristate Oleyl ethoxy Inyristate Diglycol stearate Ethylene glycol monostearate Myristyl stearate Isopropyl lanolate Paraffin waxes Glycyrrhizic acid Hydrocyethyl stearate amide Humectants Urea Glycerin Sorbitol Sodium 2-pyrrolidone-5carboxylate Soluble collagen Dibutyl phthalate Gelatin P0 lyg lycerogen Propylene glycol Butylene glycol Ethyl hexanediol C1.
10 polyethylene glycols Hyaluronic acid Lactic acid sodium pyrrolidone cArboxy late Sodium lactate orotic acid Ant ise~tiCS/Preservatives /Antioxidants/ Chelating Agents Cetyl pyridinium chloride Tribromosalicylalil ide Benzalkonium chloride Dehydroacetic acid Methyl paraben Propyl paraben Sodium dehydroacetate EDTA Benzyl alcohol Chlorobutanol Dichlorobenzyl alcohol Phenethyl alcohol Antise~tics /Preservatives/Antioxidalts /ChelatinT Agents cont.
30 Phenoxyethanol Propylene glycol Chioroacetamide Imidazolidinyl urea Butyl paraben Butylated Hydroxy An iso 1 Ethyl paraben 5-chloro-2 -methyl -4isothiazolin-3 -one 2-methyl-4-isothiazol- 3-one formaldehyde Butylated Hydroxy Toluene DMDM hydantoin 2 -bromo-2 -nitropropafle- 1,3-diol Sorbic acid Citric acid Triclosan Diazolidinyl urea Benzoic acid Propyl gallate Sodium benzoate Potassium sorbate Chloroxylenol Tetrapotass jum pyrophosl Benzoxiquine 5-bromo-5-nitro-l, 3-dioxane Glutaral Tocophero 1 Zinc pyrithone Sodium borate Boric acid Isobutyl paraben 2- (hydroxymethylamile) -ethanol Paraformaldehyde Trimerosol Dodecyl gallate Hydroquinone Phenol Sodium pyritione Stearalkonium chloride Chiorobutanol Quaternium-il U.V. absorber-i Disodium phosphate Trisodium
HEDTA
Benzethonium chloride Sodium methyl paraben
DMHF
MDM hydantoin O-phenylphenol Chiorhexidine digluconate Myristalkonium chloride Ascorbylpalmitate Isopropyl parabei Benzylparaben Phenyethyl alcohol Phosphoric acid Sodium 0-phenyl phenate Chiorhexidine dihydrochioride Phenoxyisopropanol Resorcinol Dichiorophen, sodium salt T-butyl hydroquinone Dichlorophen Methylbenzethonium chloride Chlroacetamide Phenylmercuric acetate Ascorbic acid Benzyl benzoate Hydanto in Sodium sulfite Sodium bisulfite Iodine *.:325 TJ.V. Absorbers 2 -hydroxy-4 ethylhexylsalicylate 99methoxybenzophenone Menthyl anthranilate Octyl dimethyl p-aminobenzoic acid p-dimethyl aminobenz oate Digalloyl trioleate 2, 2-dihydroxy-4-methoxy benzophenone Ethyl 4-Cbis(hydroxypropyl)] aminobenzoate 2-ethyihexyl 2-cyano-3 ,3diphenylacrylate Ethyl hexyl p-methoxy cinnamate2 Ethyl 4(bis(hydroxypropyl)) aminobenzoate sulfonic acid Benzophenone-8 Benzophenone-6 Benzophenone-2 Benzophenone-l Amyl dimethyl PABA Benzophenone-4 Benzophenone-9 According to another aspect of the present invention, the aqueous phase further includes at least one polypropylene glycol, preferably tripropylene glycol. By including, e.g., tripropylene glycol in the composition, illustratively, in an amount in the range of 1% to by weight, of the total weight of the composition, a clear cosmetic antiperspirant) gel composition can be achieved, having desirable cosmetic properties such as reduced tack and reduced whitening.
While not being held to any theory, it is also thought that use of the glycol, especially a relatively high molecular weight glycol, e.g., tripropylene glycol, may reduce irritation potential by preventing other irritating agents from permeating into the skin, by preventing mechanical chafing of the skin through extended lubrication of the aluminum salt active particles on the skin surface, and, where appropriate, by avoiding any irritation by propylene glycol.
According to this aspect of the present invention, the aqueous phase can include a mixture 999* of polypropylene glycol tripropylene glycol) 35 and propylene glycol. Where the composition includes a mixture of both tripropylene glycol and propylene glycol, the mixture illustratively can be included in the aqueous phase in an amount in the range of 1%-25% by weight, of the total weight of the composition.
While not limiting, in preferred embodiments the mixture of oil phase and alkoxylated, alkyl substituted siloxane surface active agent comprises from about 10% to about 30% by weight, of the total weight of the composition, and the combination of aqueous phase and coupling agents make up from about 70% to about 90% by weight, of the total weight of the composition.
In manufacturing the composition, and to provide an optically clear product (for example, an optically clear antiperspirant product), refractive indices of a mixture of oil phase and alkoxylated, alkyl substituted silicone surface active agent, on the one hand, and a mixture of the aqueous phase and the at least one coupling agent, on the other, are measured using a suitable refractometer such as a Bausch and Lomb Abbe 3L Refractometer, and the refractive index of one of these mixtures is adjusted as necessary in order to have a refractive index of one mixture that is within 0.0005 of the other mixture. In particular, in connection with 25 antiperspirant compositions according to the present invention, the oil phase and alkoxylated, alkyl substituted silicone surface active agent are mixed and the refractive index of the mixture is optically measured. The aqueous phase is formulated using, inter alia, the active ingredient and water, and the coupling agent is mixed therewith and the refractive index of this mixture of aqueous phase and coupling agent is optically measured. If the two mixtures do not match within 0.0005, refractive indices of either mixture can be adjusted. Preferably, the mixture including the aqueous phase has its refractive index adjusted by adding a coupling agent or water to change the refractive index so that it matches the refractive index of the mixture of oil phase and surface active agent, to at least 0.0005, at 21 0 C. Adding the coupling agent to the aqueous phase increases the refractive index of the mixture, while adding water to the aqueous phase reduces the refractive index of the mixture. Following adjustment, the mixtures are again optically measured to verify sufficient matching of the refractive indices. The mixture of the aqueous phase and coupling agent is then slowly added to the mixture of the oil phase and alkoxylated, alkyl substituted siloxane surface active agent, with turbulent agitation; optionally, fragrance can then be added, and the mixture sheared by passing the resulting emulsion through a colloid mill or other suitable high shear emulsifier) to form a stable water-in-oil emulsion with desired viscosities, illustratively, in excess of 40,000 cps at room temperature (20 0 -25 0 preferably, between 75,000 and 350,000 cps, more preferably between 2 120,000 and 325,000 cps, most preferably between 200,000 and 325,000 cps.
After formation of the composition having the desired viscosity, the composition can then be packaged into conventional packages, using conventional techniques. For example, the gel can be introduced into a dispensing package (for example, a package having a top surface with slots or pores), as conventionally done in the art.
Desirably, the dispensing package is a clear package, so as to exhibit the clear composition to 35 the purchasing consumer.
*0
S
25
S
oere o° l Thereafter, the product can be dispensed from this dispensing package, by extruding the gel from the dispensing package onto the top surface, through the pores or slots, and then rubbing the exposed gel on the skin, (for example, on skin in the axillary regions), so as to deposit the active material (for example, antiperspirant active material) on the skin. This provides good deposition of the antiperspirant active material, as well as other active materials, on the skin.
In the following, specific examples of compositions within the scope of the various aspects of the present invention are set forth. These specific examples are illustrative of the present invention, and are not limiting. In.the following examples, as well as throughout the present specification, where appropriate the names utilized are the CTFA (Cosmetics, Toiletry and Fragrance Association, Inc.) names, as set forth in the CTFA International Cosmetic Ingredient Dictionary (4th Ed. 1991), the contents of which dictionary are incorporated herein by reference in their entirety.
Amounts of each of the ingredients is in percent by weight, of the total weight of the composition.
Examples 1-6 Example No.: 1 2 3 4 5 6 Inredient ALUMINUM
ZIRCONIUM
TETRACHLOROHYDREX
GLY (REZAL 36G CONC 54.00 54.00 54.00 54.00 54.00 54.00
S.
55 35 SD ALCOHOL 40 DEIONIZED WATER 10.92 ISOPRENE GLYCOL 9.06
PROPYLENE
CARBONATE 11.10 PROPYLENE
GLYCOL
DIPROPYLENE
GLYCOL
8.00 8.00 8.00 8.00 3.00 8.90 9.83 10.92 12.26 7.18 10.17 9.08 Examples 1-6 con't Example No.: Ingredient SORBITOL (70%)
GLYCERINE
CYCLOMETHI CONE AND DIMETHICONE COPOLYOL (DC3225C) 9.00 DIMETHICONE (DC 200 50cs) 7.93
PHENYL
TRIMETHI CONE (DC 556) 1.07 7.74 12.82 9.00 9.00 9.00 9.00 9.00 7.93 7.93 7.93 7.93 7.93 1.07 1.07 1.07 1.07 1.07
S
a. a a *5 a Ca a S Examples 7-9 Examnle No.
Ingredient PHENYLTRIMETHI CONE DIMETHICONE COPOLYOL AND CYCLOMETHICONE (DC 3225C) DIMETHICONE 50 cst ALUMINUM ZIRCONIUM
TETRACHLOROHYDREX
GLY (46% solution) ETHANOL (95%) DEIONIZED WATER DIPROPYLENE GLYCOL TRIPROPYLENE GLYCOL Examples 7-9 Example No.
Ingredient PPG-425 7 1.07 8 1.07 9.00 7.93 9.00 7.93 9 1.07 9.00 7.93 54-.00 8.00 9.31 54.00 8.00 10.92 9.08 54.00 8.00 8.83 11.17 9 10. 69 Examples 7-9 Example No.
Inciredient PPG-425
TOTAL
7 100.00 8 100.00 9 10.69 100.00 Examples 10 13 Example No. 10 Inaredients
ALUMINUM-ZIRCONIUM
TETRACHLOROHYDREX
GLY
(REZAL 36G CONCENTRATE) 54.00 SD 40 ALCOHOL 8.00 DEIONIZED WATER 9.20 PROPYLENE GLYCOL 10.20 TRIPROPYLENE GLYCOL CYCLOMETHICONE DIMETHICONE
COPOLYOL
(DC3225C) 9.00 DIMETHICONE 50 cs (DC 200) 7.25 PHENYL TRIMETHICONE (DC 556) 1.75 FRAGRANCE 0.60 48. 00 12 48.00 13
S
*5 55 20 S. S
S
8 .00 11.90 6. 00 7.50 9.00 7.25 1.75 0.60 8.00 11.50 10.20 23.70 9.00 7.25 1.75 0.60 8.00 8.83 11. 17 9.00 7.30 1.70 *5*S 5e *5 5
S.
S.
*SS*
S S
TOTAL
100.00 100.00 100.00 100.00 In the foregoing Examples 10-12, the refractive index of each composition without the fragrance, was 1.4075.
Thus, according to the present invention, a clear cosmetic gel composition, which can be a soft gel, containing increased amounts of the cosmetically active ingredient increased amounts of the antiperspirant active ingredient, where the composition is an antiperspirant gel composition), and also containing in both the oil phase and the aqueous phase high-refractive index materials providing cosmetic benefits, can be achieved, while maintaining clarity of the composition. This composition can be extruded through pores or slots of a conventional soft solid or soft gel dispensing container. The compositions are stable, even in the presence of conventional antiperspirant active aluminum-containing salts such as aluminum chlorohydrate or aluminum-zirconium tetrachlorohydrex-GLY. Compositions according to the present invention can be easily and simply manufactured. Moreover, the composition according to the present invention has reduced whitening and leaves a decreased residue after application, and has reduced tack. In addition, compositions according to the present invention have reduced skin irritation potential as compared to comparable .66625 commercial products.
Industrial Applicability As is clear from the foregoing, the composition of the present invention has applicability as a cosmetic composition, having various uses depending upon the active cosmetic ingredient incorporated therein. For example, the composition of the present invention has applicability as an antiperspirant composition, for application to axillary regions of the human body to at least reduce perspiration therefrom, where an 33 antiperspirant active ingredient is incorporated in the composition. As a further illustration, the composition has applicability as a deodorant composition for application to axillary regions of the human body to reduce body malodor without reducing flow of perspiration, where the composition includes a deodorant active ingredient which is not an antiperspirant an antimicrobial agent such as Triclosan, a fragrance, etc.). However, the present invention is not limited to these specific uses, and can have other uses, depending on the cosmetically active ingredient incorporated therein, and can be applied, to other parts of a body., The present invention also has applicability in forming these compositions.
While we have shown and described several embodiments in accordance with the present invention, it is understood that the same is not limited thereto, but is susceptible to numerous changes and modifications as known to one having ordinary skill in the art, and we therefore do not wish to be limited to the details shown and described herein, but intend to cover all such modifications as are encompassed by the scope of the 25 appended claims.
oo e
Claims (4)
1. A clear and mild cosmetic gel composition including an aqueous phase containing water, (ii) at least one cosmetically active ingredient in an amount sufficient to have a cosmetic effect; and (iii) at least one polypropylene glycol; an oil phase; at least one coupling agent such that the aqueous phase is uniformly distributed in the oil phase; an alkoxylated, alkyl substituted siloxane surface active agent in an amount so as to form a water-in-oil emulsion; wherein the cosmetic gel composition is a water-in-oil emulsion.
2. A clear and mild cosmetic gel composition according to claim 1 wherein the at least one polypropylene glycol includes tripropylene glycol.
3. A clear and mild cosmetic gel composition according to claim 1 or claim 2 wherein the aqueous phase includes propylene glycol.
4. A clear and mild cosmetic gel composition according to any one of the preceding claims wherein the oil phase includes silicone fluids. Dated this twenty-eighth day of July 1999 COLGATE-PALMOLIVE COMPANY Patent Attorneys for the Applicant: F B RICE CO o a*
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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AU42385/99A AU745662B2 (en) | 1995-08-18 | 1999-07-30 | Clear cosmetic gel composition |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US60/002509 | 1995-08-18 | ||
AU67182/96A AU711443B2 (en) | 1995-08-18 | 1996-08-15 | Clear cosmetic gel composition |
AU42385/99A AU745662B2 (en) | 1995-08-18 | 1999-07-30 | Clear cosmetic gel composition |
Related Parent Applications (1)
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AU67182/96A Division AU711443B2 (en) | 1995-08-18 | 1996-08-15 | Clear cosmetic gel composition |
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AU4238599A true AU4238599A (en) | 1999-09-30 |
AU745662B2 AU745662B2 (en) | 2002-03-28 |
Family
ID=3751518
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
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AU42384/99A Ceased AU745583B2 (en) | 1995-08-18 | 1999-07-30 | Clear cosmetic gel composition |
AU42385/99A Ceased AU745662B2 (en) | 1995-08-18 | 1999-07-30 | Clear cosmetic gel composition |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
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AU42384/99A Ceased AU745583B2 (en) | 1995-08-18 | 1999-07-30 | Clear cosmetic gel composition |
Country Status (1)
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AU (2) | AU745583B2 (en) |
-
1999
- 1999-07-30 AU AU42384/99A patent/AU745583B2/en not_active Ceased
- 1999-07-30 AU AU42385/99A patent/AU745662B2/en not_active Ceased
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AU4238499A (en) | 1999-09-30 |
AU745662B2 (en) | 2002-03-28 |
AU745583B2 (en) | 2002-03-21 |
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