AU4227685A - 2 - amino - pyrimidines - Google Patents

2 - amino - pyrimidines

Info

Publication number
AU4227685A
AU4227685A AU42276/85A AU4227685A AU4227685A AU 4227685 A AU4227685 A AU 4227685A AU 42276/85 A AU42276/85 A AU 42276/85A AU 4227685 A AU4227685 A AU 4227685A AU 4227685 A AU4227685 A AU 4227685A
Authority
AU
Australia
Prior art keywords
pyrimidines
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU42276/85A
Other languages
English (en)
Inventor
Masashi Hashimoto
David Hulme Robinson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fisons Ltd
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848412184A external-priority patent/GB8412184D0/en
Priority claimed from GB858500417A external-priority patent/GB8500417D0/en
Application filed by Fisons Ltd filed Critical Fisons Ltd
Publication of AU4227685A publication Critical patent/AU4227685A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU42276/85A 1984-05-12 1985-05-10 2 - amino - pyrimidines Abandoned AU4227685A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB848412184A GB8412184D0 (en) 1984-05-12 1984-05-12 Biologically active nitrogen heterocycles
GB8412184 1984-05-12
GB8500417 1985-01-08
GB858500417A GB8500417D0 (en) 1985-01-08 1985-01-08 Biologically active nitrogen heterocycles

Publications (1)

Publication Number Publication Date
AU4227685A true AU4227685A (en) 1985-11-14

Family

ID=26287736

Family Applications (1)

Application Number Title Priority Date Filing Date
AU42276/85A Abandoned AU4227685A (en) 1984-05-12 1985-05-10 2 - amino - pyrimidines

Country Status (9)

Country Link
EP (1) EP0164204A1 (OSRAM)
AU (1) AU4227685A (OSRAM)
DK (1) DK203985A (OSRAM)
ES (1) ES8609275A1 (OSRAM)
FI (1) FI851837A7 (OSRAM)
GR (1) GR851131B (OSRAM)
IL (1) IL75147A0 (OSRAM)
NO (1) NO851877L (OSRAM)
PT (1) PT80432B (OSRAM)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU569194B2 (en) * 1985-07-24 1988-01-21 Pfizer Inc. 5-hydroxy-2-amino-pyrimidines
AU591223B2 (en) * 1986-01-13 1989-11-30 American Cyanamid Company 4,5,6-substituted-2-pyrimidinamines

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8903592D0 (en) * 1989-02-16 1989-04-05 Boots Co Plc Therapeutic agents
US5064963A (en) * 1990-04-25 1991-11-12 American Cyanamid Company Process for the synthesis of n-(3-(1h-imidazol-1-yl)phenyl-4-(substituted)-2-pyrimidinamines
US5248682A (en) * 1991-01-31 1993-09-28 Warner-Lambert Company 2-substituted-4,6-di-tertiary-butyl-5-hydroxy-1,3-pyrimidines useful as antiinflammatory agents
CA2099868C (en) * 1991-01-31 2002-04-02 Thomas Richard Belliotti Substituted 4,6-di-tertiary-butyl-5-hydroxy-pyrimidines
US5177079A (en) * 1991-01-31 1993-01-05 Warner-Lambert Company 2-substituted-4,6-di-tertiarybutyl-5-hydroxy-1,3-pyrimidines useful as antiinflammatory agents
US5270319A (en) * 1991-09-09 1993-12-14 Warner-Lambert Company 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinflammatory agents
US5196431A (en) * 1992-02-24 1993-03-23 Warner-Lambert Company 2-substituted amino-4, 6-di-tertiary-buthyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents
US5220025A (en) * 1992-02-24 1993-06-15 Warner-Lambert Company 2-substituted amino-4, 6-di-tertiary-butyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents
US5276186A (en) * 1992-03-11 1994-01-04 Ciba-Geigy Corporation Process for the production of guanidine derivatives
US5521184A (en) * 1992-04-03 1996-05-28 Ciba-Geigy Corporation Pyrimidine derivatives and processes for the preparation thereof
US5516775A (en) * 1992-08-31 1996-05-14 Ciba-Geigy Corporation Further use of pyrimidine derivatives
US5543520A (en) * 1993-10-01 1996-08-06 Ciba-Geigy Corporation Pyrimidine derivatives
US5612340A (en) * 1993-10-01 1997-03-18 Ciba-Geigy Corporation Pyrimidineamine derivatives and processes for the preparation thereof
AU691834B2 (en) * 1993-10-01 1998-05-28 Novartis Ag Pharmacologically active pyridine derivatives and processes for the preparation thereof
JP2000506532A (ja) * 1996-03-13 2000-05-30 スミスクライン・ビーチャム・コーポレイション サイトカイン介在疾患の治療にて有用な新規ピリミジン化合物
US6184226B1 (en) 1998-08-28 2001-02-06 Scios Inc. Quinazoline derivatives as inhibitors of P-38 α
GB2361236B (en) 2000-03-29 2002-04-24 Cyclacel Ltd Pyrimidines useful against proliferative disorders
EP1442024B1 (en) * 2001-11-01 2008-03-19 Janssen Pharmaceutica N.V. AMINOBENZAMIDE DERIVATIVES AS GLYCOGEN SYNTHASE KINASE 3$g(b) INHIBITORS
HUP0402106A3 (en) 2001-11-01 2009-07-28 Janssen Pharmaceutica Nv Heteroaryl amines as glycogen synthase kinase 3 beta inhibitors, process for their preparation and pharmaceutical compositions containing them
TW200302728A (en) 2002-02-01 2003-08-16 Novartis Ag Substituted amines as IgE inhibitors
BRPI0412347A (pt) 2003-07-30 2006-09-05 Cyclacel Ltd 2-aminofenil-4-fenilpiridinas como inibidores de quinase
EP1732541A4 (en) * 2004-04-07 2008-03-05 Takeda Pharmaceutical CYCLIC COMPOUNDS
JP5117189B2 (ja) 2004-08-27 2013-01-09 サイクラセル リミテッド プリン及びピリミジンｃｄｋ阻害剤、並びに自己免疫疾患の治療のためのそれらの使用
CN101272685A (zh) 2005-09-27 2008-09-24 Irm责任有限公司 包含二芳基胺的化合物和组合物以及它们作为c-kit受体调节剂的用途
GB0606774D0 (en) * 2006-04-03 2006-05-10 Novartis Ag Organic compounds
WO2008137605A1 (en) 2007-05-04 2008-11-13 Irm Llc Pyrimidine derivatives and compositions as c-kit and pdgfr kinase inhibitors
CA2697077C (en) 2007-08-22 2012-10-16 Irm Llc 2-heteroarylamino-pyrimidine derivatives as kinase inhibitors
CN101784530A (zh) * 2007-08-22 2010-07-21 Irm责任有限公司 作为激酶抑制剂的5-(4-(卤代烷氧基)苯基)嘧啶-2-胺化合物和组合物
EP2299823A1 (en) * 2008-05-19 2011-03-30 The University of Tennessee Research Foundation Pyrimidine non-classical cannabinoid compounds and related methods of use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3496179A (en) * 1967-10-11 1970-02-17 Pfizer & Co C 2-amino-3,4-dihydroquinazolines
US3635979A (en) * 1969-09-29 1972-01-18 Pfizer Certain 6- and/or 7-alkoxy-substituted-2 4-bis(disubstituted amino) quinazolines
ZA706704B (en) * 1969-10-16 1972-05-31 Lilly Co Eli Immunosuppresants and anti-viral agents
US3900476A (en) * 1973-05-17 1975-08-19 Upjohn Co 2(2'-pyrimidylamino)quinazolines and their preparation
US4010269A (en) * 1975-06-16 1977-03-01 The Upjohn Company Antiviral quinazoline compositions and methods of use
DE3220118A1 (de) * 1982-05-28 1983-12-01 Bayer Ag, 5090 Leverkusen Alkylenverbrueckte guanidinothiazolderivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU569194B2 (en) * 1985-07-24 1988-01-21 Pfizer Inc. 5-hydroxy-2-amino-pyrimidines
AU591223B2 (en) * 1986-01-13 1989-11-30 American Cyanamid Company 4,5,6-substituted-2-pyrimidinamines

Also Published As

Publication number Publication date
PT80432B (en) 1987-04-16
PT80432A (en) 1985-06-01
ES8609275A1 (es) 1986-07-16
ES543047A0 (es) 1986-07-16
EP0164204A1 (en) 1985-12-11
NO851877L (no) 1985-11-13
DK203985A (da) 1985-11-13
GR851131B (OSRAM) 1985-11-25
FI851837A0 (fi) 1985-05-09
FI851837L (fi) 1985-11-13
FI851837A7 (fi) 1985-11-13
DK203985D0 (da) 1985-05-08
IL75147A0 (en) 1985-09-29

Similar Documents

Publication Publication Date Title
AU4227685A (en) 2 - amino - pyrimidines
AU4568985A (en) Tryptamine-5-methanesulfonamide
AU4401185A (en) Belastungsabhangig frequenzvariabler herzschrittmacher
AU4222285A (en) Pyrrolobenzimidazoles
AU3839785A (en) Sammelpackung
AU4254685A (en) Arylhydroxamates
AU4256585A (en) 1-heteroaryl-4-aryl-pyrazolin-5-ones
AU3749685A (en) Induktionsmotor
AU4105285A (en) Tetrahydrofuran-2-ylmethylamines
AU4061285A (en) Schaltersicherungseinheit
AU4118385A (en) Verbindungselement
AU4299085A (en) Medizinisches schwingbett
AU4541685A (en) Bandspanne
AU4422985A (en) Leucotriene-antagonistic thioethehers
AU4459585A (en) Morpholinols
AU4542985A (en) Linear-antriebsvorrichtung
AU4544085A (en) Fiberdoseringsanordning
AU4357485A (en) Injektionsspritze
AU4061585A (en) Automatisk fadolsaftapningsanlaeg
AU4274285A (en) Cycloalkane-indene-carboximidamides
AU4271085A (en) Metallophosphoaluminates
AU4216685A (en) Aminocarnitines
AU4356785A (en) Reinigungsburste
AU4489185A (en) Pyridazinylimidazolinones
AU3067684A (en) Helicoplane