AU4162096A - Method for identifying protective antigens for eliciting neutralizing antibodies - Google Patents

Method for identifying protective antigens for eliciting neutralizing antibodies

Info

Publication number
AU4162096A
AU4162096A AU41620/96A AU4162096A AU4162096A AU 4162096 A AU4162096 A AU 4162096A AU 41620/96 A AU41620/96 A AU 41620/96A AU 4162096 A AU4162096 A AU 4162096A AU 4162096 A AU4162096 A AU 4162096A
Authority
AU
Australia
Prior art keywords
antibody
antigen
virus
antibody molecule
hsv
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU41620/96A
Other languages
English (en)
Inventor
Carlos F. Barbas Iii
Dennis R Burton
Paul W. H. I Parren
Anthony R Williamson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Institute filed Critical Scripps Research Institute
Publication of AU4162096A publication Critical patent/AU4162096A/en
Abandoned legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036Retroviridae, e.g. leukemia viruses
    • C07K16/1045Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • AIDS & HIV (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU41620/96A 1994-11-10 1995-11-13 Method for identifying protective antigens for eliciting neutralizing antibodies Abandoned AU4162096A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33795594A 1994-11-10 1994-11-10
US337955 1994-11-10
PCT/US1995/014907 WO1996015273A1 (en) 1994-11-10 1995-11-13 Method for identifying protective antigens for eliciting neutralizing antibodies

Publications (1)

Publication Number Publication Date
AU4162096A true AU4162096A (en) 1996-06-06

Family

ID=23322759

Family Applications (1)

Application Number Title Priority Date Filing Date
AU41620/96A Abandoned AU4162096A (en) 1994-11-10 1995-11-13 Method for identifying protective antigens for eliciting neutralizing antibodies

Country Status (5)

Country Link
EP (1) EP0787211A1 (ja)
JP (1) JPH10509237A (ja)
AU (1) AU4162096A (ja)
CA (1) CA2204863A1 (ja)
WO (1) WO1996015273A1 (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1429143A4 (en) * 2001-08-22 2006-04-12 Inst Antibodies Co Ltd SELECTION PROCEDURE FOR BINDING MOLECULES
CA2463931A1 (en) 2001-10-16 2003-04-24 The Government Of The United States Of America, Represented By The Secre Tary, Department Of Health And Human Services Broadly cross-reactive neutralizing antibodies against human immunodeficiency virus selected by env-cd4-co-receptor complexes
CA2484930A1 (en) 2002-05-06 2003-11-13 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Identification of novel broadly cross-reactive neutralizing human monoclonal antibodies using sequential antigen panning of phage display libraries
WO2003095492A1 (en) 2002-05-06 2003-11-20 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Identification of novel broadly cross-reactive hiv-1 neutralizing human monoclonal antibodies
CA2585574A1 (en) * 2004-10-29 2006-05-11 Government Of The United States Of America, Represented By The Secretary , Department Of Health And Human Services Broadly cross-reactive hiv-1 neutralizing human monoclonal antibodies

Also Published As

Publication number Publication date
WO1996015273A1 (en) 1996-05-23
CA2204863A1 (en) 1996-05-23
EP0787211A1 (en) 1997-08-06
JPH10509237A (ja) 1998-09-08

Similar Documents

Publication Publication Date Title
Burton et al. Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody
US5652138A (en) Human neutralizing monoclonal antibodies to human immunodeficiency virus
EP0675904B1 (en) Human neutralizing monoclonal antibodies to human immunodeficiency virus
Tudor et al. HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4+ cell infection: an IgA gene and functional analysis
US6156313A (en) Human monoclonal antibodies to herpes simplex virus and methods therefor
US6461612B2 (en) Anti-idiotypic antibody and its use in diagnosis and therapy in HIV-related disease
Ditzel et al. Neutralizing recombinant human antibodies to a conformational V2-and CD4-binding site-sensitive epitope of HIV-1 gp120 isolated by using an epitope-masking procedure.
US6395275B1 (en) Synthetic human neutralizing monoclonal antibodies to human immunodeficiency virus
EP0671927B1 (en) Human neutralizing monoclonal antibodies to respiratory syncytial virus
US7060799B2 (en) Antibody for ligand capture assay
WO2011046623A2 (en) Hiv-1 antibodies
EP0851924A1 (en) Neutralizing monoclonal antibodies to respiratory syncytial virus
WO1994007922A9 (en) Human neutralizing monoclonal antibodies to human immunodeficiency virus
US20020081576A1 (en) Antibodies directed against binding-associated epitopes
ES2320051T3 (es) Anticuerpos monoclonales humanos especificos del antigeno e2 del virus de la hepatitis c (hcv).
Glamann et al. Simian immunodeficiency virus (SIV) envelope-specific Fabs with high-level homologous neutralizing activity: recovery from a long-term-nonprogressor SIV-infected macaque
AU4162096A (en) Method for identifying protective antigens for eliciting neutralizing antibodies
US20030187247A1 (en) Human neutralizing monoclonal antibodies to human immunodeficiency virus
WO1994025490A1 (en) Human monoclonal antibodies to human cytomegalovirus, and methods therefor
AU745489B2 (en) Human neutralizing monoclonal antibodies to human immunodeficiency virus
AU737135B2 (en) Human neutralizing monoclonal antibodies to human immunodeficiency virus
Hirsch et al. Simian Immunodeficiency Virus (SIV)