AU3878895A - Use of nitric oxide donors in medicine - Google Patents

Use of nitric oxide donors in medicine

Info

Publication number
AU3878895A
AU3878895A AU38788/95A AU3878895A AU3878895A AU 3878895 A AU3878895 A AU 3878895A AU 38788/95 A AU38788/95 A AU 38788/95A AU 3878895 A AU3878895 A AU 3878895A AU 3878895 A AU3878895 A AU 3878895A
Authority
AU
Australia
Prior art keywords
medicine
nitric oxide
oxide donors
donors
nitric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU38788/95A
Inventor
Adam Julian De Belder
Edward John Langford
Christoph Christopher Lees
John Martin
Marek Radomski
Daryl David Rees
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kings College London
Wellcome Foundation Ltd
Original Assignee
Kings College London
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kings College London, Wellcome Foundation Ltd filed Critical Kings College London
Publication of AU3878895A publication Critical patent/AU3878895A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A61K38/063—Glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU38788/95A 1994-11-25 1995-11-24 Use of nitric oxide donors in medicine Abandoned AU3878895A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9423868 1994-11-25
GB9423868A GB9423868D0 (en) 1994-11-25 1994-11-25 Compounds for use in medicine
PCT/GB1995/002745 WO1996016645A1 (en) 1994-11-25 1995-11-24 Use of nitric oxide donors in medicine

Publications (1)

Publication Number Publication Date
AU3878895A true AU3878895A (en) 1996-06-19

Family

ID=10765012

Family Applications (1)

Application Number Title Priority Date Filing Date
AU38788/95A Abandoned AU3878895A (en) 1994-11-25 1995-11-24 Use of nitric oxide donors in medicine

Country Status (3)

Country Link
AU (1) AU3878895A (en)
GB (1) GB9423868D0 (en)
WO (1) WO1996016645A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6911427B1 (en) 1995-09-15 2005-06-28 Duke University No-modified hemoglobins and uses therefore
US6197745B1 (en) 1995-09-15 2001-03-06 Duke University Methods for producing nitrosated hemoglobins and therapeutic uses therefor
US6855691B1 (en) 1995-09-15 2005-02-15 Duke University Methods for producing and using S-nitrosohemoglobins
US6627738B2 (en) 1995-09-15 2003-09-30 Duke University No-modified hemoglobins and uses therefor
US6916471B2 (en) 1995-09-15 2005-07-12 Duke University Red blood cells loaded with S-nitrosothiol and uses therefor
US6153186A (en) 1995-09-15 2000-11-28 Duke University Medical Center Red blood cells loaded with S-nitrosothiol and uses therefor
US6232434B1 (en) 1996-08-02 2001-05-15 Duke University Medical Center Polymers for delivering nitric oxide in vivo
US5770645A (en) * 1996-08-02 1998-06-23 Duke University Medical Center Polymers for delivering nitric oxide in vivo
US6057367A (en) 1996-08-30 2000-05-02 Duke University Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses
IT1288123B1 (en) * 1996-09-04 1998-09-10 Nicox Sa USE OF NITRO-DERIVATIVES FOR URINARY INCONTINENCE
ES2147162B1 (en) 1999-01-27 2001-03-16 Lacer Sa "S-NITROSOTIOLS AS AGENTS FOR THE TREATMENT OF CIRCULATORY DYSFUNCTIONS".
US6589759B1 (en) 1999-03-30 2003-07-08 Trustees Of Boston University Compositions and methods for producing platelets and/or proplatelets from megakaryocytes
CA2410632A1 (en) 2000-06-22 2001-12-27 David S. Garvey Nitrosated and nitrosylated taxanes, compositions and methods of use
US7049308B2 (en) 2000-10-26 2006-05-23 Duke University C-nitroso compounds and use thereof
US6359182B1 (en) 2000-10-26 2002-03-19 Duke University C-nitroso compounds and use thereof
AU2003270540A1 (en) * 2002-09-11 2004-04-30 Nitromed, Inc. Treatment of cyclooxygenase-3 mediated diseases and disorders
WO2022107160A1 (en) 2020-11-20 2022-05-27 Institute Of Life Sciences Composition for enhancing intra-cellular nitric oxide generation

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5025001A (en) * 1988-06-15 1991-06-18 Brigham And Women's Hospital S-nitroso derivatives of ACE inhibitors and the use thereof
US5385937A (en) * 1991-04-10 1995-01-31 Brigham & Women's Hospital Nitrosation of homocysteine as a method for treating homocysteinemia
US5185376A (en) * 1991-09-24 1993-02-09 The United States Of America As Represented By The Department Of Health And Human Services Therapeutic inhibition of platelet aggregation by nucleophile-nitric oxide complexes and derivatives thereof
EP0676964B1 (en) * 1991-11-14 2001-01-24 Brigham And Women's Hospital Nitrosylation of enzyme sh groups as a therapeutic modality
DE4222933A1 (en) * 1992-07-11 1994-01-13 Cassella Ag Use of new and known thiaza heterocyclic N-nitrosimine cpds. - as nitrogen mon:oxide mediating pharmaceuticals to treat and prevent e.g. hypertension, angina, thrombosis and erectile dysfunction
US5405919A (en) * 1992-08-24 1995-04-11 The United States Of America As Represented By The Secretary Of Health And Human Services Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions and methods of treating biological disorders
US5650447A (en) * 1992-08-24 1997-07-22 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Nitric oxide-releasing polymers to treat restenosis and related disorders
WO1994016729A1 (en) * 1993-01-28 1994-08-04 Neorx Corporation Targeted nitric oxide pathway or nitric oxide synthase modulation
CA2164632A1 (en) * 1993-06-11 1994-12-22 John P. Cooke Treatment of vascular degenerative diseases by modulation of endogenous nitric oxide production or activity
CA2106105C (en) * 1993-09-14 2008-03-18 Larry K. Keefer Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
AU698748B2 (en) * 1993-09-17 1998-11-05 Brigham And Women's Hospital Use of nitric oxide-adducts to prevent thrombosis on artificial and vascular surfaces
AU704173B2 (en) * 1993-11-02 1999-04-15 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College, The Use of nitric oxide releasing compounds as protective agents in ischemia reperfusion injury
US5482925A (en) * 1994-03-17 1996-01-09 Comedicus Incorporated Complexes of nitric oxide with cardiovascular amines as dual acting cardiovascular agents
DE4410997A1 (en) * 1994-03-30 1995-10-26 Isis Pharma Gmbh Pharmaceutical preparations and drugs for the prevention and treatment of endothelial dysfunctions
DE4420523A1 (en) * 1994-06-13 1995-12-14 Cassella Ag Treating and preventing SIRS, e.g. in shock, arthritis or peritonitis

Also Published As

Publication number Publication date
GB9423868D0 (en) 1995-01-11
WO1996016645A1 (en) 1996-06-06

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