AU3875400A - Hydrazide inhibitors of hiv-1 integrase - Google Patents

Hydrazide inhibitors of hiv-1 integrase

Info

Publication number
AU3875400A
AU3875400A AU38754/00A AU3875400A AU3875400A AU 3875400 A AU3875400 A AU 3875400A AU 38754/00 A AU38754/00 A AU 38754/00A AU 3875400 A AU3875400 A AU 3875400A AU 3875400 A AU3875400 A AU 3875400A
Authority
AU
Australia
Prior art keywords
integrase
hiv
hydrazide
inhibitors
hydrazide inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU38754/00A
Inventor
Terrence Burke
Zhaiwei Lin
Nouri Neamati
Yves Pommier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Institutes of Health NIH
Original Assignee
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services filed Critical US Department of Health and Human Services
Publication of AU3875400A publication Critical patent/AU3875400A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU38754/00A 1999-03-12 2000-03-10 Hydrazide inhibitors of hiv-1 integrase Abandoned AU3875400A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12430299P 1999-03-12 1999-03-12
US60124302 1999-03-12
PCT/US2000/006361 WO2000053577A1 (en) 1999-03-12 2000-03-10 Hydrazide inhibitors of hiv-1 integrase

Publications (1)

Publication Number Publication Date
AU3875400A true AU3875400A (en) 2000-09-28

Family

ID=22414041

Family Applications (1)

Application Number Title Priority Date Filing Date
AU38754/00A Abandoned AU3875400A (en) 1999-03-12 2000-03-10 Hydrazide inhibitors of hiv-1 integrase

Country Status (2)

Country Link
AU (1) AU3875400A (en)
WO (1) WO2000053577A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101200504B (en) * 2006-12-11 2010-05-12 上海百瑞吉生物医药有限公司 Macromolecule thiolated modified derivatives and cross-linking material thereof
CN108484645A (en) * 2018-03-26 2018-09-04 新疆大学 A kind of pyrazolone-shrinking salicylyl hydrazine closes preparation and the bioactivity of copper complex

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3930674A1 (en) * 1989-09-11 1991-03-21 Diagnostikforschung Inst BIFUNCTIONAL CHELATE FORMERS FOR COMPLEXING TC AND RE-ISOTOPES, METHOD FOR THE PRODUCTION AND DISPLAY OF CONJUGATES THEREOF AND THEIR USE IN DIAGNOSTICS AND THERAPY
DE19536783A1 (en) * 1995-09-21 1997-03-27 Diagnostikforschung Inst Bifunctional nicotinamide chelating agents of the type N¶2¶S¶2¶ for radioactive isotopes

Also Published As

Publication number Publication date
WO2000053577A1 (en) 2000-09-14
WO2000053577A9 (en) 2001-09-20

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase