AU3494293A - Thiazolyl-pyridine derivatives and their use as gastric acid secretion inhibitors - Google Patents

Thiazolyl-pyridine derivatives and their use as gastric acid secretion inhibitors

Info

Publication number
AU3494293A
AU3494293A AU34942/93A AU3494293A AU3494293A AU 3494293 A AU3494293 A AU 3494293A AU 34942/93 A AU34942/93 A AU 34942/93A AU 3494293 A AU3494293 A AU 3494293A AU 3494293 A AU3494293 A AU 3494293A
Authority
AU
Australia
Prior art keywords
thiazolyl
gastric acid
acid secretion
pyridine derivatives
secretion inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU34942/93A
Inventor
Robert John Ife
Colin Andrew Leach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Intercredit BV
Original Assignee
SmithKline Beecham Intercredit BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Intercredit BV filed Critical SmithKline Beecham Intercredit BV
Publication of AU3494293A publication Critical patent/AU3494293A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU34942/93A 1992-01-27 1993-01-26 Thiazolyl-pyridine derivatives and their use as gastric acid secretion inhibitors Abandoned AU3494293A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929201692A GB9201692D0 (en) 1992-01-27 1992-01-27 Compounds
GB9201692 1992-01-27

Publications (1)

Publication Number Publication Date
AU3494293A true AU3494293A (en) 1993-09-01

Family

ID=10709305

Family Applications (1)

Application Number Title Priority Date Filing Date
AU34942/93A Abandoned AU3494293A (en) 1992-01-27 1993-01-26 Thiazolyl-pyridine derivatives and their use as gastric acid secretion inhibitors

Country Status (5)

Country Link
EP (1) EP0625151A1 (en)
JP (1) JPH07503023A (en)
AU (1) AU3494293A (en)
GB (1) GB9201692D0 (en)
WO (1) WO1993015071A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2302417A1 (en) 1997-10-27 1999-05-06 Takeda Chemical Industries, Ltd. Adenosine a3 receptor antagonists
AU2001244618A1 (en) * 2000-03-30 2001-10-15 Takeda Chemical Industries Ltd. Substituted 1,3-thiazole compounds, their production and use
UA80393C2 (en) 2000-12-07 2007-09-25 Алтана Фарма Аг Pharmaceutical preparation comprising an pde inhibitor dispersed on a matrix
GB0102668D0 (en) * 2001-02-02 2001-03-21 Glaxo Group Ltd Compounds
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
CA2499429C (en) 2002-09-18 2010-09-21 Pfizer Products Inc. Novel oxazole and thiazole compounds as transforming growth factor (tgf) inhibitors
BR0314577A (en) 2002-09-18 2005-08-09 Pfizer Prod Inc Triazole derivatives as transforming growth factor (tgf) inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3486009T2 (en) * 1983-09-09 1993-04-15 Takeda Chemical Industries Ltd 5-PYRIDYL-1,3-THIAZOL DERIVATIVES, THEIR PRODUCTION AND USE.
US4697012A (en) * 1984-07-25 1987-09-29 Merck & Co., Inc. Morpholino pyridyl thiazole compound
US5021435A (en) * 1988-01-22 1991-06-04 Sumitomo Pharmaceuticals Company, Limited Certain pyridyl-thiazolidin-4-one having anti-ulcer activity

Also Published As

Publication number Publication date
JPH07503023A (en) 1995-03-30
WO1993015071A1 (en) 1993-08-05
GB9201692D0 (en) 1992-03-11
EP0625151A1 (en) 1994-11-23

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