AU3249997A - Method of assaying compounds which affect the activity of g protein-coupled receptors based on measurement of receptor oligomerization - Google Patents

Method of assaying compounds which affect the activity of g protein-coupled receptors based on measurement of receptor oligomerization

Info

Publication number
AU3249997A
AU3249997A AU32499/97A AU3249997A AU3249997A AU 3249997 A AU3249997 A AU 3249997A AU 32499/97 A AU32499/97 A AU 32499/97A AU 3249997 A AU3249997 A AU 3249997A AU 3249997 A AU3249997 A AU 3249997A
Authority
AU
Australia
Prior art keywords
protein
affect
activity
measurement
coupled receptors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU32499/97A
Other languages
English (en)
Inventor
Michel Bouvier
Michael Dennis
Terence E. Hebert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite de Montreal
Biosignal Inc
Original Assignee
Universite de Montreal
Biosignal Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite de Montreal, Biosignal Inc filed Critical Universite de Montreal
Publication of AU3249997A publication Critical patent/AU3249997A/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU32499/97A 1996-07-01 1997-06-30 Method of assaying compounds which affect the activity of g protein-coupled receptors based on measurement of receptor oligomerization Abandoned AU3249997A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2071796P 1996-07-01 1996-07-01
US60020717 1996-07-01
PCT/CA1997/000455 WO1998000715A2 (en) 1996-07-01 1997-06-30 Method of assaying compounds which affect the activity of g protein-coupled receptors based on measurement of receptor oligomerization

Publications (1)

Publication Number Publication Date
AU3249997A true AU3249997A (en) 1998-01-21

Family

ID=21800162

Family Applications (1)

Application Number Title Priority Date Filing Date
AU32499/97A Abandoned AU3249997A (en) 1996-07-01 1997-06-30 Method of assaying compounds which affect the activity of g protein-coupled receptors based on measurement of receptor oligomerization

Country Status (4)

Country Link
EP (1) EP0939902A2 (de)
AU (1) AU3249997A (de)
CA (2) CA2209511A1 (de)
WO (1) WO1998000715A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985584A (en) * 1997-02-19 1999-11-16 American Cyanamid Company Method to identify plant proteins that function in G protein coupled systems and compositions therefor
WO2002046763A1 (en) * 2000-12-04 2002-06-13 Novo Nordisk A/S Method of identifying compounds capable of acting as agonists or antagonists of g-protein coupled receptors
TWI264121B (en) 2001-11-30 2006-10-11 Semiconductor Energy Lab A display device, a method of manufacturing a semiconductor device, and a method of manufacturing a display device
ATE419274T1 (de) 2002-10-25 2009-01-15 Mds Analytical Technologies Us Verfahren zur identifizierung von transmembranrezeptoragonisten mit reduzierter internalisierung
CA3086337A1 (en) 2017-12-19 2019-06-27 Gpcr Therapeutics, Inc. Gpcr heteromer inhibitors and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2160038A1 (en) * 1995-07-14 1997-01-15 Biosignal Inc. Methods of screening compounds for their pharmacological relevance based on downregulation of recombinant receptors
WO1998000538A2 (en) * 1996-07-01 1998-01-08 Biosignal Inc. Peptides and peptidomimetic compounds affecting the activity of g-protein-coupled receptors by altering receptor oligomerization

Also Published As

Publication number Publication date
WO1998000715A3 (en) 1998-04-23
EP0939902A2 (de) 1999-09-08
CA2209511A1 (en) 1998-01-01
CA2259131A1 (en) 1998-01-08
WO1998000715A2 (en) 1998-01-08

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