AU3080792A - Slow-release flurbiprofen-containing medicament and its use - Google Patents
Slow-release flurbiprofen-containing medicament and its useInfo
- Publication number
- AU3080792A AU3080792A AU30807/92A AU3080792A AU3080792A AU 3080792 A AU3080792 A AU 3080792A AU 30807/92 A AU30807/92 A AU 30807/92A AU 3080792 A AU3080792 A AU 3080792A AU 3080792 A AU3080792 A AU 3080792A
- Authority
- AU
- Australia
- Prior art keywords
- flurbiprofen
- slow
- medicament
- containing medicament
- racemate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2063—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
Abstract
A medicament contains as active substance a slow-release composition of flurbiprofen as a racemate, a mixture of a racemate with its enantiomers, a pseudoracemate (mixtures of equal parts of S- and R-flurbiprofen) or as a mixture of different parts of S- and R-flurbiprofen in the range extending between pure S- and pure R-flurbiprofen, in the form of a gelatine-based pharmaceutically applicable nanosol. This medicament satisfies the requirements of an efficient anti-rheumatic and/or analgesic therapy.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4140183A DE4140183C2 (en) | 1991-12-05 | 1991-12-05 | Retard form for a medicine containing flurbiprofen |
DE4140183 | 1991-12-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
AU3080792A true AU3080792A (en) | 1993-06-28 |
Family
ID=6446388
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU30807/92A Abandoned AU3080792A (en) | 1991-12-05 | 1992-12-04 | Slow-release flurbiprofen-containing medicament and its use |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0615447B1 (en) |
AT (1) | ATE134876T1 (en) |
AU (1) | AU3080792A (en) |
DE (2) | DE4140183C2 (en) |
DK (1) | DK0615447T3 (en) |
ES (1) | ES2085657T3 (en) |
GR (1) | GR3020144T3 (en) |
WO (1) | WO1993010771A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10047319A1 (en) | 2000-09-25 | 2002-04-18 | Paz Arzneimittelentwicklung | Use of R-arylpropionic acids for the production of medicaments for the treatment of diseases which can be therapeutically influenced by inhibiting the activation of the nuclear transcription factor AP-1 |
DE102004041340A1 (en) * | 2004-08-20 | 2006-02-23 | Deutsche Gelatine-Fabriken Stoess Ag | Nanoparticles and process for their preparation |
US20110269704A1 (en) | 2009-07-24 | 2011-11-03 | Seigfried Bernd G | Method for developing a liquid composition to be applied to the skin as a foam and a composition that can be applied topically |
TR201721036A2 (en) * | 2017-12-21 | 2019-07-22 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | MODULATED EMISSION FORMULATIONS OF FLURBIPROPHEN |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4107288A (en) * | 1974-09-18 | 1978-08-15 | Pharmaceutical Society Of Victoria | Injectable compositions, nanoparticles useful therein, and process of manufacturing same |
DE3205504C2 (en) * | 1982-02-16 | 1983-12-01 | Dolorgiet Gmbh & Co Kg, 5300 Bonn | Topical drug containing ibuprofen |
US4571333A (en) * | 1983-06-14 | 1986-02-18 | Syntex (U.S.A.) Inc. | Controlled release naproxen and naproxen sodium tablets |
US4826689A (en) * | 1984-05-21 | 1989-05-02 | University Of Rochester | Method for making uniformly sized particles from water-insoluble organic compounds |
DE3532562A1 (en) * | 1985-09-12 | 1987-03-12 | Dolorgiet Gmbh & Co Kg | TRANSDERMALLY RESORBABLE, WATER-BASED PREPARATIONS OF ARYLPROPIONIC ACID DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF |
GB8524421D0 (en) * | 1985-10-03 | 1985-11-06 | Boots Co Plc | Therapeutic agents |
JPS62126122A (en) * | 1985-11-27 | 1987-06-08 | Showa Shinyaku Kk | Production of ibuprofen granule having coated surface |
GB8601204D0 (en) * | 1986-01-18 | 1986-02-19 | Boots Co Plc | Therapeutic agents |
US4780320A (en) * | 1986-04-29 | 1988-10-25 | Pharmetrix Corp. | Controlled release drug delivery system for the periodontal pocket |
US4704436A (en) * | 1986-05-02 | 1987-11-03 | Barabas Eugene S | Water soluble complex of a poly(vinylpyrrolidone) copolymer and α-methyl-(2-methylpropyl)benzene acetic acid |
IT1200178B (en) * | 1986-07-23 | 1989-01-05 | Alfa Farmaceutici Spa | GALENIC FORMULATIONS WITH SCHEDULED SALE CONTAINING DRUGS WITH ANTI-FLOGISTIC ACTIVITY |
DE3669103D1 (en) * | 1986-11-14 | 1990-04-05 | Puetter Medice Chem Pharm | MEDICINAL PRODUCT CONTAINING IBUPROFEN. |
HU205861B (en) * | 1986-12-19 | 1992-07-28 | Sandoz Ag | Process for producing hydrosole of pharmaceutically effective material |
FR2608988B1 (en) * | 1986-12-31 | 1991-01-11 | Centre Nat Rech Scient | PROCESS FOR THE PREPARATION OF COLLOIDAL DISPERSIBLE SYSTEMS OF A SUBSTANCE, IN THE FORM OF NANOPARTICLES |
CH673395A5 (en) * | 1987-01-30 | 1990-03-15 | Ciba Geigy Ag | |
CA1324083C (en) * | 1987-03-09 | 1993-11-09 | Tetsu Miyoshi | Pharmaceutical preparations containing non-steroidal anti-inflammatory agents |
US4806359A (en) * | 1987-04-22 | 1989-02-21 | Mcneilab, Inc. | Iburprofen sustained release matrix and process |
US4980375A (en) * | 1987-07-10 | 1990-12-25 | Sterling Drug Inc. | Onset-hastened/enhanced antipyretic response |
US4851444A (en) * | 1987-07-10 | 1989-07-25 | Analgesic Associates | Onset-hastened/enhanced analgesia |
US4861797A (en) * | 1987-10-15 | 1989-08-29 | Oratech Pharmaceutical Development Corporation | Liquid ibuprofen compositions and methods of making them |
US4859704A (en) * | 1987-10-15 | 1989-08-22 | Oratech Pharmaceutical Development Corporation | Water soluble ibuprofen compositions and methods of making them |
US4868214A (en) * | 1987-11-17 | 1989-09-19 | Analgesic Associates | Onset-hastened/enhanced analgesia |
US4835188A (en) * | 1987-12-08 | 1989-05-30 | American Home Products Corporation | Spray dried ibuprofen |
US4996209A (en) * | 1988-06-20 | 1991-02-26 | Alcon Laboratories, Inc. | Ophthalmic antiinflammatory compositions comprising S(+)-flurbiprofen |
DE3824353A1 (en) * | 1988-07-19 | 1990-01-25 | Paz Arzneimittelentwicklung | METHOD FOR SEPARATING MIXED ENANTIOMER ARYLPROPIONIC ACIDS |
AU6758990A (en) * | 1989-11-06 | 1991-05-31 | Sepracor, Inc. | Analgesic composition containing optically pure s(+) flurbiprofen |
DE3938227C1 (en) * | 1989-11-17 | 1991-05-02 | Dolorgiet Gmbh & Co Kg, 5205 St Augustin, De | Oral antiinflammatory and analgetic pharmaceutical compsn. - comprises magnesium ibuprofen dissolved in mixt. of water, propane-1,2-diol and glycerol |
DE4028906A1 (en) * | 1990-09-12 | 1992-03-19 | Paz Arzneimittelentwicklung | MEDICINAL PRODUCTS AND THEIR PREPARATION AND THEIR USE IN THE CONTROL OF PAIN AND / OR DEFENSE AND / OR FEVER OF ANIMALS AND PEOPLE |
-
1991
- 1991-12-05 DE DE4140183A patent/DE4140183C2/en not_active Expired - Fee Related
-
1992
- 1992-12-04 ES ES92924552T patent/ES2085657T3/en not_active Expired - Lifetime
- 1992-12-04 EP EP92924552A patent/EP0615447B1/en not_active Expired - Lifetime
- 1992-12-04 DE DE59205626T patent/DE59205626D1/en not_active Expired - Fee Related
- 1992-12-04 AU AU30807/92A patent/AU3080792A/en not_active Abandoned
- 1992-12-04 AT AT92924552T patent/ATE134876T1/en not_active IP Right Cessation
- 1992-12-04 WO PCT/DE1992/001015 patent/WO1993010771A1/en active IP Right Grant
- 1992-12-04 DK DK92924552.0T patent/DK0615447T3/en active
-
1996
- 1996-05-31 GR GR960401526T patent/GR3020144T3/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE4140183C2 (en) | 1995-12-21 |
ES2085657T3 (en) | 1996-06-01 |
DE59205626D1 (en) | 1996-04-11 |
EP0615447A1 (en) | 1994-09-21 |
DE4140183A1 (en) | 1993-06-17 |
GR3020144T3 (en) | 1996-08-31 |
EP0615447B1 (en) | 1996-03-06 |
ATE134876T1 (en) | 1996-03-15 |
DK0615447T3 (en) | 1996-04-01 |
WO1993010771A1 (en) | 1993-06-10 |
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