AU2783397A - Isopentenyl pyrophosphate isomerase (ipi) and/or prenyl transferase inhibitors - Google Patents

Isopentenyl pyrophosphate isomerase (ipi) and/or prenyl transferase inhibitors

Info

Publication number
AU2783397A
AU2783397A AU27833/97A AU2783397A AU2783397A AU 2783397 A AU2783397 A AU 2783397A AU 27833/97 A AU27833/97 A AU 27833/97A AU 2783397 A AU2783397 A AU 2783397A AU 2783397 A AU2783397 A AU 2783397A
Authority
AU
Australia
Prior art keywords
ipi
transferase inhibitors
isopentenyl pyrophosphate
prenyl transferase
pyrophosphate isomerase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU27833/97A
Other languages
English (en)
Inventor
Richard John Brown
Michael John Rogers
Robert Graham Goodwin Russel
Donald Jeremy Watts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Sheffield
Original Assignee
University of Sheffield
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9610174.6A external-priority patent/GB9610174D0/en
Priority claimed from GBGB9708329.9A external-priority patent/GB9708329D0/en
Application filed by University of Sheffield filed Critical University of Sheffield
Publication of AU2783397A publication Critical patent/AU2783397A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/533—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving isomerase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU27833/97A 1996-05-15 1997-05-12 Isopentenyl pyrophosphate isomerase (ipi) and/or prenyl transferase inhibitors Abandoned AU2783397A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9610174 1996-05-15
GBGB9610174.6A GB9610174D0 (en) 1996-05-15 1996-05-15 Prenyl transferase inhibitors
GB9708329 1997-04-25
GBGB9708329.9A GB9708329D0 (en) 1997-04-25 1997-04-25 Isopentenyl pyrophosphate iosmerase (IPI) and/or prenyl transferase inhibitors
PCT/GB1997/001302 WO1997043437A2 (en) 1996-05-15 1997-05-12 Isopentenyl pyrophosphate isomerase (ipi) and/or prenyl transferase inhibitors

Publications (1)

Publication Number Publication Date
AU2783397A true AU2783397A (en) 1997-12-05

Family

ID=26309338

Family Applications (1)

Application Number Title Priority Date Filing Date
AU27833/97A Abandoned AU2783397A (en) 1996-05-15 1997-05-12 Isopentenyl pyrophosphate isomerase (ipi) and/or prenyl transferase inhibitors

Country Status (3)

Country Link
EP (1) EP0952834A2 (de)
AU (1) AU2783397A (de)
WO (1) WO1997043437A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2736981A1 (en) 1998-04-14 1999-10-21 Kyowa Hakko Bio Co., Ltd. Process for producing isoprenoid compounds by microorganisms
US7008645B2 (en) * 1998-07-14 2006-03-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem Method of inhibiting restenosis using bisphosphonates
IL125336A0 (en) * 1998-07-14 1999-03-12 Yissum Res Dev Co Compositions for inhibition and treatment of restinosis
US6984400B2 (en) * 1998-07-14 2006-01-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Method of treating restenosis using bisphosphonate nanoparticles
US6423519B1 (en) * 1998-07-15 2002-07-23 Gpc Biotech Inc. Compositions and methods for inhibiting fungal growth
TR200101841T2 (tr) * 1998-12-23 2001-12-21 Jomaa Pharmaka Gmbh Enfeksiyonlardan korunmak ve enfeksiyon tedavisi için bifosfonatların kullanılmaları
JP2002537819A (ja) * 1999-03-05 2002-11-12 メルク エンド カムパニー インコーポレーテッド ファルネシル二リン酸シンターゼの阻害に有用な化合物の同定方法
PT1408984E (pt) * 2001-07-20 2008-12-26 Bioagency Ag Compostos organofosforosos para activar células t gama/delta
DE10242940A1 (de) * 2002-09-16 2004-03-18 Bayer Cropscience Ag Verfahren zum Identifizieren von fungizid wirksamen Verbindungen
US10517883B2 (en) 2003-06-27 2019-12-31 Zuli Holdings Ltd. Method of treating acute myocardial infarction
DE102005025191A1 (de) * 2005-06-01 2006-12-14 Bayer Cropscience Ag Verfahren zum Identifizieren von fungizid wirksamen Verbindungen basierend auf Isopentenylpyrophosphat-Isomerasen
KR101034299B1 (ko) * 2008-12-02 2011-05-16 고려대학교 산학협력단 Ｔｒｐｖ３ 활성 조절 약물 및 이의 활용
KR101034300B1 (ko) 2008-12-02 2011-05-16 고려대학교 산학협력단 Ｔｒｐｖ３ 활성 억제 약물 및 이의 활용
US9290526B2 (en) 2010-05-28 2016-03-22 The Royal Institution For The Advancement Of Learning/Mcgill University Heterocyclyl-pyridinyl-based biphosphonic acid, pharmaceutically acceptable salt thereof, composition thereof and method of use thereof
WO2011147038A1 (en) 2010-05-28 2011-12-01 The Royal Institution For The Advancement Of Learning/Mcgill University Heterocyclyl-pyridinyl-based biphosphonic acid, pharmaceutically acceptable salt thereof, composition thereof and method of use thereof
US9993427B2 (en) 2013-03-14 2018-06-12 Biorest Ltd. Liposome formulation and manufacture
CN112980809B (zh) * 2021-03-17 2023-04-11 云南中烟工业有限责任公司 一种烟草法尼基焦磷酸合酶基因及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH675422A5 (de) * 1988-03-31 1990-09-28 Symphar Sa
US5503973A (en) * 1992-05-29 1996-04-02 The Regents Of The University Of California Method for inhibition of viral morphogenesis

Also Published As

Publication number Publication date
WO1997043437A2 (en) 1997-11-20
WO1997043437A3 (en) 1998-02-26
EP0952834A2 (de) 1999-11-03

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