AU1851697A - Inhibitors of farnesyl-protein transferase - Google Patents
Inhibitors of farnesyl-protein transferaseInfo
- Publication number
- AU1851697A AU1851697A AU18516/97A AU1851697A AU1851697A AU 1851697 A AU1851697 A AU 1851697A AU 18516/97 A AU18516/97 A AU 18516/97A AU 1851697 A AU1851697 A AU 1851697A AU 1851697 A AU1851697 A AU 1851697A
- Authority
- AU
- Australia
- Prior art keywords
- farnesyl
- inhibitors
- protein transferase
- transferase
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1086096P | 1996-01-30 | 1996-01-30 | |
US60/010860 | 1996-01-30 | ||
GB9605699 | 1996-03-19 | ||
GBGB9605699.9A GB9605699D0 (en) | 1996-03-19 | 1996-03-19 | Inhibitors of farnesyl-protein transferase |
PCT/US1997/001599 WO1997027752A1 (en) | 1996-01-30 | 1997-01-27 | Inhibitors of farnesyl-protein transferase |
Publications (2)
Publication Number | Publication Date |
---|---|
AU1851697A true AU1851697A (en) | 1997-08-22 |
AU712504B2 AU712504B2 (en) | 1999-11-11 |
Family
ID=26308951
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU18516/97A Ceased AU712504B2 (en) | 1996-01-30 | 1997-01-27 | Inhibitors of farnesyl-protein transferase |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0880320A4 (en) |
AU (1) | AU712504B2 (en) |
CA (1) | CA2243507A1 (en) |
WO (1) | WO1997027752A1 (en) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5929250A (en) * | 1997-01-23 | 1999-07-27 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
EP1091736A4 (en) | 1998-07-02 | 2001-10-24 | Merck & Co Inc | Inhibitors of prenyl-protein transferase |
US6410534B1 (en) | 1998-07-02 | 2002-06-25 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
FR2780892B1 (en) * | 1998-07-08 | 2001-08-17 | Sod Conseils Rech Applic | USE OF PRENYLTRANSFERASE INHIBITORS FOR THE PREPARATION OF A MEDICINAL PRODUCT FOR TREATING CONDITIONS RESULTING FROM MEMBRANE FIXATION OF HETEROTRIMERIC PROTEIN |
US6525069B1 (en) | 1998-12-18 | 2003-02-25 | Bristol-Myers Squibb Pharma Co. | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity |
US6331541B1 (en) | 1998-12-18 | 2001-12-18 | Soo S. Ko | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity |
WO2000035876A1 (en) | 1998-12-18 | 2000-06-22 | Du Pont Pharmaceuticals Company | 2-substituted-4-nitrogen heterocycles as modulators of chemokine receptor activity |
NZ511394A (en) | 1998-12-18 | 2003-07-25 | Du Pont Pharm Co | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity |
CA2347909A1 (en) | 1998-12-18 | 2000-06-22 | Joseph B. Santella, Iii | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity |
AU3126700A (en) | 1998-12-18 | 2000-07-03 | Du Pont Pharmaceuticals Company | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity |
US6897234B2 (en) | 1999-12-17 | 2005-05-24 | Bristol-Myers Squibb Pharma Company | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity |
AU2001251444A1 (en) | 2000-04-10 | 2001-10-23 | Merck And Co., Inc. | Inhibitors of prenyl-protein transferase |
DE10025782A1 (en) | 2000-05-26 | 2001-12-06 | Basf Ag | Liquid crystalline mixture |
EP1162194A1 (en) * | 2000-06-06 | 2001-12-12 | Aventis Pharma Deutschland GmbH | Factor VIIa inhibitory (thio)urea derivatives, their preparation and their use |
WO2002002525A2 (en) | 2000-06-30 | 2002-01-10 | Bristol-Myers Squibb Pharma Company | N-ureidoheterocycloaklyl-piperidines as modulators of chemokine receptor activity |
AU2002326948A1 (en) | 2001-09-18 | 2003-04-01 | Bristol-Myers Squibb Company | Piperizinones as modulators of chemokine receptor activity |
TW200409630A (en) | 2002-09-12 | 2004-06-16 | Bristol Myers Squibb Co | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity |
AU2003275257A1 (en) | 2002-09-26 | 2004-04-19 | Bristol-Myers Squibb Company | N-substituted heterocyclic amines as modulators of chemokine receptor activity |
AU2003259007A1 (en) * | 2002-10-31 | 2004-05-25 | Amersham Biosciences Ab | Use of urea variants as affinity ligands |
EP2095819A1 (en) | 2008-02-28 | 2009-09-02 | Maastricht University | N-benzyl imidazole derivatives and their use as aldosterone synthase inhibitors |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4576957A (en) * | 1984-07-05 | 1986-03-18 | American Cyanamid Company | N-(Substituted phenyl)-N'-[(1H-imidazol-1-yl) and (1H-1,2,4-triazol-1-yl)alkyl]ureas |
JPH09504277A (en) * | 1993-09-30 | 1997-04-28 | メルク エンド カンパニー インコーポレーテッド | Farnesyl-protein transferase inhibitors |
IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Pharmaceutical compositions for inhibition of g-protein function and for treatment of proliferative diseases containing tricyclic compounds some such compounds and process for preparing part of them |
AU1615895A (en) * | 1994-03-31 | 1995-10-12 | Bristol-Myers Squibb Company | Imidazole-containing inhibitors of farnesyl protein transferase |
WO1996010034A2 (en) * | 1994-09-29 | 1996-04-04 | Merck & Co., Inc. | Thiol-free inhibitors of farnesyl-protein transferase |
US5756528A (en) * | 1995-06-06 | 1998-05-26 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
EP0862435A4 (en) * | 1995-11-22 | 1999-02-03 | Merck & Co Inc | Inhibitors of farnesyl-protein transferase |
JP2000504014A (en) * | 1996-01-30 | 2000-04-04 | メルク エンド カンパニー インコーポレーテッド | Farnesyl-protein transferase inhibitor |
US6090948A (en) * | 1996-01-30 | 2000-07-18 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
AU703988B2 (en) * | 1996-01-30 | 1999-04-01 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
JP2000507581A (en) * | 1996-04-03 | 2000-06-20 | メルク エンド カンパニー インコーポレーテッド | Farnesyl-protein transferase inhibitor |
CA2250143A1 (en) * | 1996-04-03 | 1997-10-09 | Jeffrey Bergman | Inhibitors of farnesyl-protein transferase |
CA2250937A1 (en) * | 1996-04-03 | 1997-10-09 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
AU715658B2 (en) * | 1996-04-03 | 2000-02-10 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
-
1997
- 1997-01-27 EP EP97904147A patent/EP0880320A4/en not_active Withdrawn
- 1997-01-27 WO PCT/US1997/001599 patent/WO1997027752A1/en not_active Application Discontinuation
- 1997-01-27 AU AU18516/97A patent/AU712504B2/en not_active Ceased
- 1997-01-27 CA CA 2243507 patent/CA2243507A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU712504B2 (en) | 1999-11-11 |
CA2243507A1 (en) | 1997-08-07 |
EP0880320A4 (en) | 1999-06-16 |
EP0880320A1 (en) | 1998-12-02 |
WO1997027752A1 (en) | 1997-08-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU703203B2 (en) | Inhibitors of farnesyl-protein transferase | |
AU2734797A (en) | Inhibitors of farnesyl-protein transferase | |
AU2670297A (en) | Inhibitors of farnesyl-protein transferase | |
AU2593097A (en) | Inhibitors of farnesyl-protein transferase | |
AU2253097A (en) | Inhibitors of farnesyl-protein transferase | |
AU2430197A (en) | Inhibitors of farnesyl-protein transferase | |
AU1988495A (en) | Inhibitors of farnesyl-protein transferase | |
AU2555997A (en) | Inhibitors of farnesyl-protein transferase | |
AU3373195A (en) | Inhibitors of farnesyl-protein transferase | |
AU2598897A (en) | Inhibitors of farnesyl-protein transferase | |
AU2605897A (en) | Inhibitors of farnesyl-protein transferase | |
GB9604311D0 (en) | Inhibitors of farnesyl-protein transferase | |
AU2552497A (en) | Inhibitors of farnesyl-protein transferase | |
AU2605797A (en) | Inhibitors of farnesyl-protein transferase | |
AU1851697A (en) | Inhibitors of farnesyl-protein transferase | |
AU2587597A (en) | Inhibitors of farnesyl-protein transferase | |
AU2432697A (en) | Inhibitors of farnesyl-protein transferase | |
AU2432597A (en) | Inhibitors of farnesyl-protein transferase | |
AU2430397A (en) | Inhibitors of farnesyl-protein transferase | |
AU2554897A (en) | Inhibitors of farnesyl-protein transferase | |
EP0891352A4 (en) | Inhibitors of farnesyl-protein transferase | |
AU2600597A (en) | Inhibitors of farnesyl-protein transferase | |
AU2602097A (en) | Inhibitors of farnesyl-protein transferase | |
AU2593297A (en) | Inhibitors of farnesyl-protein transferase | |
AU1952697A (en) | Inhibitors of farnesyl-protein transferase |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |