AU2718088A - Process for extracting pure fractions of lactoperoxidase and lactoferrin from milk serum - Google Patents
Process for extracting pure fractions of lactoperoxidase and lactoferrin from milk serumInfo
- Publication number
- AU2718088A AU2718088A AU27180/88A AU2718088A AU2718088A AU 2718088 A AU2718088 A AU 2718088A AU 27180/88 A AU27180/88 A AU 27180/88A AU 2718088 A AU2718088 A AU 2718088A AU 2718088 A AU2718088 A AU 2718088A
- Authority
- AU
- Australia
- Prior art keywords
- lactoperoxidase
- lactoferrin
- pct
- milk serum
- pure fractions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000010445 Lactoferrin Human genes 0.000 title abstract 4
- 108010063045 Lactoferrin Proteins 0.000 title abstract 4
- 108010023244 Lactoperoxidase Proteins 0.000 title abstract 4
- 102000045576 Lactoperoxidases Human genes 0.000 title abstract 4
- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 title abstract 4
- 229940078795 lactoferrin Drugs 0.000 title abstract 4
- 235000021242 lactoferrin Nutrition 0.000 title abstract 4
- 229940057428 lactoperoxidase Drugs 0.000 title abstract 4
- 235000013336 milk Nutrition 0.000 title abstract 3
- 239000008267 milk Substances 0.000 title abstract 3
- 210000004080 milk Anatomy 0.000 title abstract 3
- 210000002966 serum Anatomy 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
- A23C9/146—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by ion-exchange
- A23C9/1465—Chromatographic separation of protein or lactose fraction; Adsorption of protein or lactose fraction followed by elution
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
- A23C9/142—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
- A23C9/1425—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration by ultrafiltration, microfiltration or diafiltration of whey, e.g. treatment of the UF permeate
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
- A23J1/205—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey from whey, e.g. lactalbumine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/814—Enzyme separation or purification
- Y10S435/815—Enzyme separation or purification by sorption
Abstract
PCT No. PCT/SE88/00643 Sec. 371 Date May 24, 1990 Sec. 102(e) Date May 24, 1990 PCT Filed Nov. 25, 1988 PCT Pub. No. WO89/04608 PCT Pub. Date Jun. 1, 1989.A process for extracting pure fractions of lactoperoxidase and lactoferrin from milk serum is described. The milk serum is microfiltered and passed through a strong cation exchanger at a high rate of flow for selective adsorption of lactoperoxidase and lactoferrin, and then the lactoperoxidase and lactoferrin are eluted successively and selectively with saline solutions having different concentrations.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8704719A SE458818B (en) | 1987-11-27 | 1987-11-27 | PROCEDURE FOR EXTRACTION OF PURE FRACTIONS OF LACTOPEROXIDAS AND LACTOFERRIN FROM MILK SERUM |
SE8704719 | 1987-11-27 | ||
PCT/SE1988/000643 WO1989004608A1 (en) | 1987-11-27 | 1988-11-25 | Process for extracting pure fractions of lactoperoxidase and lactoferrin from milk serum |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2718088A true AU2718088A (en) | 1989-06-14 |
AU613688B2 AU613688B2 (en) | 1991-08-08 |
Family
ID=20370415
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU27180/88A Ceased AU613688B2 (en) | 1987-11-27 | 1988-11-25 | Process for extracting pure fractions of lactoperoxidase and lactoferrin from milk serum |
Country Status (12)
Country | Link |
---|---|
US (1) | US5149647A (en) |
EP (1) | EP0390821B1 (en) |
JP (1) | JP2553180B2 (en) |
AT (1) | ATE89454T1 (en) |
AU (1) | AU613688B2 (en) |
DE (1) | DE3881217T2 (en) |
DK (1) | DK173642B1 (en) |
FI (1) | FI91032C (en) |
NO (1) | NO177268C (en) |
NZ (1) | NZ227097A (en) |
SE (1) | SE458818B (en) |
WO (1) | WO1989004608A1 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993002098A1 (en) * | 1991-07-25 | 1993-02-04 | Commonwealth Scientific And Industrial Research Organisation | Isolation of charged particles from fluids |
WO1996008155A1 (en) * | 1994-09-16 | 1996-03-21 | New Zealand Dairy Board | Physical separation of casein and whey proteins |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4879110A (en) * | 1983-10-27 | 1989-11-07 | Stolle Research And Development Corporation | Antihypertensive hyperimmune milk, production, composition, and use |
DE69033553T2 (en) * | 1989-11-03 | 2001-01-18 | Incyte Pharma Inc | RECOMBINANT PRODUCTION OF LACTOPEROXIDASE |
US5756333A (en) * | 1989-11-03 | 1998-05-26 | Incyte Pharmaceuticals, Inc. | Recombinant production of lactoperoxidase |
JP3035833B2 (en) * | 1991-01-21 | 2000-04-24 | 雪印乳業株式会社 | Method for producing sialic acids-containing composition |
JP3110078B2 (en) * | 1991-06-21 | 2000-11-20 | 森永乳業株式会社 | Mass production of high-purity antimicrobial peptides |
US5596082A (en) * | 1992-01-15 | 1997-01-21 | Campina Melkunie Bv | Process for isolating lactoferrin and lactoperoxidase from milk and milk products, and products obtained by such process |
JPH05202098A (en) * | 1992-01-29 | 1993-08-10 | Snow Brand Milk Prod Co Ltd | Production of physiologically active substance from lactic material |
SE470375B (en) * | 1992-05-07 | 1994-02-07 | Alfa Laval Food Eng Ab | Ways to obtain high quality protein products from whey |
US5756680A (en) * | 1994-01-05 | 1998-05-26 | Sepragen Corporation | Sequential separation of whey proteins and formulations thereof |
US5468844A (en) * | 1994-01-07 | 1995-11-21 | Protose Technologies Inc. | Process for the membrane-filtering of protein solutions |
US5861491A (en) * | 1994-02-16 | 1999-01-19 | Pharming B.V. | Isolation of lactoferrin from milk |
JP3112637B2 (en) * | 1994-09-30 | 2000-11-27 | 雪印乳業株式会社 | Bone strengthener |
JP2974604B2 (en) * | 1996-01-23 | 1999-11-10 | 雪印乳業株式会社 | Basic protein composition, basic peptide composition and use thereof |
JP3073439B2 (en) * | 1996-02-08 | 2000-08-07 | 雪印乳業株式会社 | Bone formation promotion and bone resorption inhibitor |
CA2197515A1 (en) * | 1996-07-15 | 1998-01-16 | Reyad Mahmoud | Methods of treating milk products |
CA2261695A1 (en) * | 1996-07-30 | 1998-02-05 | Shionogi & Co., Ltd. | Method for preventing adsorption of lactoferrin |
CA2264630C (en) | 1996-09-06 | 2006-12-12 | Pall Corporation | Shear separation method and system |
JP4082782B2 (en) * | 1998-04-30 | 2008-04-30 | 雪印乳業株式会社 | Periodontal disease prevention and improvement agent |
US20030040475A1 (en) † | 2001-01-16 | 2003-02-27 | Yasuhiro Toba | Agents for improving lipid metabolism and reducing high blood pressure |
US6875459B2 (en) * | 2001-09-10 | 2005-04-05 | Henry B. Kopf | Method and apparatus for separation of milk, colostrum, and whey |
FR2841747B1 (en) * | 2002-07-02 | 2004-08-20 | Cie Laitiere Europeenne | MILK PROTEIN ISOLATE AND PROCESS FOR ITS PREPARATION |
WO2004020977A2 (en) * | 2002-08-29 | 2004-03-11 | University Of Massachusetts | Utilization of emulsion interface engineering to produce oxidatively stable lipid delivery systems |
ZA200502320B (en) * | 2002-09-20 | 2006-10-25 | Pharmacia Corp | Process for decreasing aggregate levels of pegylated protein |
JP4263932B2 (en) * | 2003-04-01 | 2009-05-13 | 雪印乳業株式会社 | Method for producing lactoferrin |
US20040259770A1 (en) * | 2003-06-19 | 2004-12-23 | Rush University Medical Center | Method for determining leukocyte activation |
US7547770B2 (en) * | 2003-11-03 | 2009-06-16 | Advanced Protein Systems | Colostral fractionation process |
US7932069B2 (en) * | 2004-02-17 | 2011-04-26 | Morinaga Milk Industry Co., Ltd. | Process for producing lactoperoxidase |
US7125963B2 (en) * | 2004-03-03 | 2006-10-24 | En N Tech Inc | Treatments for contaminant reduction in lactoferrin preparations and lactoferrin containing compositions |
US20070142629A1 (en) * | 2004-06-16 | 2007-06-21 | Ciphergen Biosystems, Inc. | Multichemistry fractionation |
DK1879908T3 (en) | 2005-05-10 | 2014-03-31 | Murray Goulburn Coop Co Ltd | IMMUNOGLOBULIN INFRINGEMENT AND PROCEDURE |
FR2889068B1 (en) * | 2005-07-29 | 2012-03-02 | Cie Laitiere Europeenne | NOVEL DAIRY PROTEIN FRACTIONS AND THEIR USE FOR THE PREVENTION OR TREATMENT OF CHRONIC INFLAMMATORY DISEASES |
US20070212367A1 (en) * | 2006-03-13 | 2007-09-13 | Keech Andrew M | Novel immunologically active peptide fragments of a proline-rich polypeptide isolated from colostral mammalian fluids for treatment of viral and non-viral diseases or diseased conditions |
NZ583234A (en) | 2007-07-10 | 2012-06-29 | Glanbia Nutritionals | Method for removing endotoxin from proteins |
CN101861332B (en) * | 2007-11-01 | 2014-04-02 | 雪印惠乳业株式会社 | Food material for promoting the differentiation of osteoblast and inhibiting the differentiation of osteoclast |
US9055752B2 (en) * | 2008-11-06 | 2015-06-16 | Intercontinental Great Brands Llc | Shelf-stable concentrated dairy liquids and methods of forming thereof |
UA112972C2 (en) | 2010-09-08 | 2016-11-25 | Інтерконтінентал Грейт Брендс ЛЛС | LIQUID DAIRY CONCENTRATE WITH A HIGH CONTENT OF DRY SUBSTANCES |
ES2561460T3 (en) | 2012-11-15 | 2016-02-26 | Arla Foods Amba | Method for producing a composition that contains the casein macropeptide |
CZ2013885A3 (en) * | 2013-11-15 | 2015-08-19 | Univerzita Palackého | Process of whey protein separation from milk medium and apparatus for its implementation |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3896241A (en) * | 1971-09-01 | 1975-07-22 | Coca Cola Co | Preparation of a whey protein concentrate |
FR2505615A1 (en) * | 1981-05-15 | 1982-11-19 | Elf Aquitaine | PROCESS FOR THE EXTRACTION OF LACTOFERRIN AND IMMUNOGLOBULINS FROM MILK |
JPS61145200A (en) * | 1984-12-19 | 1986-07-02 | Snow Brand Milk Prod Co Ltd | Separation and purification of bovine lactoferrin |
FR2584727B1 (en) * | 1985-07-11 | 1988-06-17 | Roussel Uclaf | PROCESS FOR EXTRACTING MILK PROTEINS, PRODUCTS, APPLICATION OF THE PROCESS, AND PHARMACEUTICAL COMPOSITIONS |
IE61701B1 (en) * | 1986-07-17 | 1994-11-30 | Morinaga Milk Industry Co Ltd | Process for producing bovine lactoferrin in high purity |
FR2616628B1 (en) * | 1987-06-19 | 1989-09-29 | Entremont Sa | PROCESS FOR EXTRACTING WHEY PROTEINS BY ADSORPTION AND ELUTION |
-
1987
- 1987-11-27 SE SE8704719A patent/SE458818B/en not_active IP Right Cessation
-
1988
- 1988-11-25 JP JP63509492A patent/JP2553180B2/en not_active Expired - Fee Related
- 1988-11-25 DE DE88910417T patent/DE3881217T2/en not_active Expired - Fee Related
- 1988-11-25 US US07/488,040 patent/US5149647A/en not_active Expired - Lifetime
- 1988-11-25 AT AT88910417T patent/ATE89454T1/en not_active IP Right Cessation
- 1988-11-25 AU AU27180/88A patent/AU613688B2/en not_active Ceased
- 1988-11-25 WO PCT/SE1988/000643 patent/WO1989004608A1/en active IP Right Grant
- 1988-11-25 EP EP88910417A patent/EP0390821B1/en not_active Expired - Lifetime
- 1988-11-28 NZ NZ227097A patent/NZ227097A/en unknown
-
1990
- 1990-05-18 DK DK199001245A patent/DK173642B1/en not_active IP Right Cessation
- 1990-05-23 FI FI902562A patent/FI91032C/en not_active IP Right Cessation
- 1990-05-25 NO NO902328A patent/NO177268C/en not_active IP Right Cessation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993002098A1 (en) * | 1991-07-25 | 1993-02-04 | Commonwealth Scientific And Industrial Research Organisation | Isolation of charged particles from fluids |
WO1996008155A1 (en) * | 1994-09-16 | 1996-03-21 | New Zealand Dairy Board | Physical separation of casein and whey proteins |
Also Published As
Publication number | Publication date |
---|---|
FI91032B (en) | 1994-01-31 |
DK124590A (en) | 1990-05-25 |
DK173642B1 (en) | 2001-05-14 |
NO177268C (en) | 1995-08-16 |
FI91032C (en) | 1994-05-10 |
SE458818B (en) | 1989-05-16 |
JPH03502921A (en) | 1991-07-04 |
US5149647A (en) | 1992-09-22 |
FI902562A0 (en) | 1990-05-23 |
DE3881217D1 (en) | 1993-06-24 |
DE3881217T2 (en) | 1994-01-05 |
ATE89454T1 (en) | 1993-06-15 |
NO902328D0 (en) | 1990-05-25 |
AU613688B2 (en) | 1991-08-08 |
NZ227097A (en) | 1991-01-29 |
NO902328L (en) | 1990-05-25 |
DK124590D0 (en) | 1990-05-18 |
EP0390821B1 (en) | 1993-05-19 |
JP2553180B2 (en) | 1996-11-13 |
NO177268B (en) | 1995-05-08 |
EP0390821A1 (en) | 1990-10-10 |
SE8704719D0 (en) | 1987-11-27 |
WO1989004608A1 (en) | 1989-06-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Assignment registered |
Owner name: CAMPINA MELKUNIE B.V. Free format text: FORMER OWNER WAS: SVENSKA MEJERIERNAS RIKSFORENINGS EKONOMI-AKTIEBOLAG |