AU2504192A - Protein kinase c inhibition and novel compound balanol - Google Patents
Protein kinase c inhibition and novel compound balanolInfo
- Publication number
- AU2504192A AU2504192A AU25041/92A AU2504192A AU2504192A AU 2504192 A AU2504192 A AU 2504192A AU 25041/92 A AU25041/92 A AU 25041/92A AU 2504192 A AU2504192 A AU 2504192A AU 2504192 A AU2504192 A AU 2504192A
- Authority
- AU
- Australia
- Prior art keywords
- balanol
- inhibition
- protein kinase
- novel compound
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/12—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US748632 | 1985-06-24 | ||
US74863291A | 1991-08-22 | 1991-08-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2504192A true AU2504192A (en) | 1993-03-16 |
Family
ID=25010269
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU25041/92A Abandoned AU2504192A (en) | 1991-08-22 | 1992-08-21 | Protein kinase c inhibition and novel compound balanol |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0664706A1 (en) |
JP (1) | JPH06510280A (en) |
AU (1) | AU2504192A (en) |
CA (1) | CA2115994A1 (en) |
WO (1) | WO1993003730A1 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09503994A (en) * | 1993-03-03 | 1997-04-22 | イーライ・リリー・アンド・カンパニー | Balanoid |
AU686691B2 (en) * | 1994-01-12 | 1998-02-12 | F. Hoffmann-La Roche Ag | Novel azepanes and homologs thereof |
US5583221A (en) * | 1994-05-04 | 1996-12-10 | Eli Lilly And Company | Substituted fused and bridged bicyclic compounds as therapeutic agents |
TW339325B (en) * | 1995-07-05 | 1998-09-01 | Hoffmann La Roche | Novel azepane derivatives, process for the preparation thereof and pharmaceutical composition containing the same |
AU1540997A (en) * | 1996-02-09 | 1997-08-28 | Phytera Symbion Aps | Balanol analogues |
US5902882A (en) * | 1996-04-17 | 1999-05-11 | Hoffmann-La Roche Inc. | Assymetric synthesis of azepines |
US6914140B1 (en) | 1996-04-17 | 2005-07-05 | Hoffmann-La Roche Inc. | Asymmetric synthesis process |
US6232299B1 (en) * | 1996-05-01 | 2001-05-15 | Eli Lilly And Company | Use of protein kinase C inhibitors to enhance the clinical efficacy of oncolytic agents and radiation therapy |
US8252754B2 (en) | 2005-03-21 | 2012-08-28 | The Trustees Of Columbia University In The City Of New York | Neuronal pain pathway |
US8846742B2 (en) | 2006-02-14 | 2014-09-30 | The Trustees Of Columbia University In The City Of New York | Neuronal pain pathway modulators |
-
1992
- 1992-08-21 JP JP5502446A patent/JPH06510280A/en active Pending
- 1992-08-21 WO PCT/US1992/007124 patent/WO1993003730A1/en not_active Application Discontinuation
- 1992-08-21 CA CA002115994A patent/CA2115994A1/en not_active Abandoned
- 1992-08-21 EP EP92919060A patent/EP0664706A1/en not_active Withdrawn
- 1992-08-21 AU AU25041/92A patent/AU2504192A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2115994A1 (en) | 1993-03-04 |
EP0664706A4 (en) | 1995-06-14 |
WO1993003730A1 (en) | 1993-03-04 |
EP0664706A1 (en) | 1995-08-02 |
JPH06510280A (en) | 1994-11-17 |
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