AU2360992A - Novel 2-amino naphthyridine derivative, its preparation and use - Google Patents

Novel 2-amino naphthyridine derivative, its preparation and use

Info

Publication number
AU2360992A
AU2360992A AU23609/92A AU2360992A AU2360992A AU 2360992 A AU2360992 A AU 2360992A AU 23609/92 A AU23609/92 A AU 23609/92A AU 2360992 A AU2360992 A AU 2360992A AU 2360992 A AU2360992 A AU 2360992A
Authority
AU
Australia
Prior art keywords
preparation
novel
naphthyridine derivative
formula
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU23609/92A
Other versions
AU669482B2 (en
Inventor
Marie-Therese David-Comte
Gerard Roussel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of AU2360992A publication Critical patent/AU2360992A/en
Application granted granted Critical
Publication of AU669482B2 publication Critical patent/AU669482B2/en
Assigned to AVENTIS PHARMA S.A. reassignment AVENTIS PHARMA S.A. Request to Amend Deed and Register Assignors: RHONE-POULENC RORER S.A.
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

New 2-aminonaphthyridine derivative of formula: <IMAGE> its optical isomers, its salts and its preparation. The product of formula (I) is particularly useful for preparing the automer of the product of formula: <IMAGE> which exhibits notable therapeutic properties.
AU23609/92A 1991-07-12 1992-07-10 Novel 2-amino naphthyridine derivative, its preparation and use Expired AU669482B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9108827 1991-07-12
FR9108827A FR2678931B1 (en) 1991-07-12 1991-07-12 NEW DERIVATIVE OF AMINO-2 NAPHTYRIDINE, ITS PREPARATION AND ITS USE.
PCT/FR1992/000669 WO1993001190A1 (en) 1991-07-12 1992-07-10 Novel 2-amino naphthyridine derivative, its preparation and use

Publications (2)

Publication Number Publication Date
AU2360992A true AU2360992A (en) 1993-02-11
AU669482B2 AU669482B2 (en) 1996-06-13

Family

ID=9415045

Family Applications (1)

Application Number Title Priority Date Filing Date
AU23609/92A Expired AU669482B2 (en) 1991-07-12 1992-07-10 Novel 2-amino naphthyridine derivative, its preparation and use

Country Status (18)

Country Link
EP (2) EP0598765B1 (en)
JP (1) JP2712114B2 (en)
KR (1) KR100235376B1 (en)
AT (1) ATE129499T1 (en)
AU (1) AU669482B2 (en)
CA (1) CA2112979C (en)
DE (1) DE69205685T2 (en)
DK (1) DK0598765T3 (en)
ES (1) ES2079200T3 (en)
FR (1) FR2678931B1 (en)
GR (1) GR3017889T3 (en)
IE (1) IE69386B1 (en)
IL (1) IL102443A0 (en)
MA (1) MA22586A1 (en)
MX (1) MX9204056A (en)
NZ (1) NZ243495A (en)
WO (1) WO1993001190A1 (en)
ZA (1) ZA925100B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU657568B2 (en) * 1991-07-12 1995-03-16 Aventis Pharma S.A. Method for preparing optical isomers of a 2-amino naphthyridine derivative
AU657569B2 (en) * 1991-07-12 1995-03-16 Aventis Pharma S.A. Method for the preparation of optical isomers of a 2-amino naphthyridine derivative
AU658662B2 (en) * 1991-07-12 1995-04-27 Aventis Pharma S.A. Process for the preparation of a dextrogyral isomer of an isoindolinone derivative

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2313060A1 (en) * 1974-11-07 1976-12-31 Rhone Poulenc Ind Pyrrolidinone deriirrivs as tranquillizers - 1-Heterocyclyl-5(1-piperazinyl-carbonyloxy)-2(5H)-pyrrolidinone derivs prepd. from 5-aryloxycarbonyloxy cpds. and piperazine (OE060576)
FR2321290A1 (en) * 1975-04-07 1977-03-18 Rhone Poulenc Ind 1,8-naphthyridine tranquillisers, e hypnotics, anti-epileptics etc. - 2-substd. by isoindoline, pyrrolo-(3,4-b)-pyrazines, pyrrolo-(3,4-b)-pyridine or oxathino-(1,4)(2,3-c)-pyrrole
FR2607503B1 (en) * 1986-12-02 1989-02-24 Rhone Poulenc Sante NOVEL ISOINDOLINONE DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU657568B2 (en) * 1991-07-12 1995-03-16 Aventis Pharma S.A. Method for preparing optical isomers of a 2-amino naphthyridine derivative
AU657569B2 (en) * 1991-07-12 1995-03-16 Aventis Pharma S.A. Method for the preparation of optical isomers of a 2-amino naphthyridine derivative
AU658662B2 (en) * 1991-07-12 1995-04-27 Aventis Pharma S.A. Process for the preparation of a dextrogyral isomer of an isoindolinone derivative

Also Published As

Publication number Publication date
MA22586A1 (en) 1993-04-01
EP0598765B1 (en) 1995-10-25
JPH06509086A (en) 1994-10-13
GR3017889T3 (en) 1996-01-31
EP0598765A1 (en) 1994-06-01
ZA925100B (en) 1993-04-28
ATE129499T1 (en) 1995-11-15
AU669482B2 (en) 1996-06-13
JP2712114B2 (en) 1998-02-10
FR2678931B1 (en) 1993-09-24
ES2079200T3 (en) 1996-01-01
EP0522969A1 (en) 1993-01-13
IL102443A0 (en) 1993-01-14
KR100235376B1 (en) 1999-12-15
CA2112979C (en) 2003-09-30
CA2112979A1 (en) 1993-01-21
FR2678931A1 (en) 1993-01-15
IE922235A1 (en) 1993-01-13
WO1993001190A1 (en) 1993-01-21
DK0598765T3 (en) 1995-12-04
IE69386B1 (en) 1996-09-18
DE69205685D1 (en) 1995-11-30
NZ243495A (en) 1994-11-25
DE69205685T2 (en) 1996-03-21
MX9204056A (en) 1993-01-01

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Legal Events

Date Code Title Description
HB Alteration of name in register

Owner name: AVENTIS PHARMA S.A.

Free format text: FORMER NAME WAS: RHONE-POULENC RORER S.A.