AU2247599A - Process of making 3-aryloxy, 4-aryl furan-2-ones useful as inhibitors of cox-2 - Google Patents

Process of making 3-aryloxy, 4-aryl furan-2-ones useful as inhibitors of cox-2

Info

Publication number
AU2247599A
AU2247599A AU22475/99A AU2247599A AU2247599A AU 2247599 A AU2247599 A AU 2247599A AU 22475/99 A AU22475/99 A AU 22475/99A AU 2247599 A AU2247599 A AU 2247599A AU 2247599 A AU2247599 A AU 2247599A
Authority
AU
Australia
Prior art keywords
cox
aryloxy
inhibitors
making
ones useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU22475/99A
Inventor
Cheng Y. Chen
Robert D Larsen
Lushi Tan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9815805.8A external-priority patent/GB9815805D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU2247599A publication Critical patent/AU2247599A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60—Two oxygen atoms, e.g. succinic anhydride
AU22475/99A 1997-09-24 1998-09-21 Process of making 3-aryloxy, 4-aryl furan-2-ones useful as inhibitors of cox-2 Abandoned AU2247599A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US6069497P 1997-09-24 1997-09-24
US60/060694 1997-09-24
GB9815805 1998-07-21
GBGB9815805.8A GB9815805D0 (en) 1998-07-21 1998-07-21 Chemical process
PCT/US1998/019642 WO1999015513A1 (en) 1997-09-24 1998-09-21 Process of making 3-aryloxy, 4-aryl furan-2-ones useful as inhibitors of cox-2

Publications (1)

Publication Number Publication Date
AU2247599A true AU2247599A (en) 1999-04-12

Family

ID=26314074

Family Applications (1)

Application Number Title Priority Date Filing Date
AU22475/99A Abandoned AU2247599A (en) 1997-09-24 1998-09-21 Process of making 3-aryloxy, 4-aryl furan-2-ones useful as inhibitors of cox-2

Country Status (7)

Country Link
EP (1) EP1017687A4 (en)
JP (1) JP3516658B2 (en)
CN (1) CN1271352A (en)
AU (1) AU2247599A (en)
EA (1) EA002690B1 (en)
SK (1) SK4202000A3 (en)
WO (1) WO1999015513A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001232175B2 (en) 2000-03-03 2005-07-07 Pfizer Products Inc. Pyrazole ether derivatives as anti-inflammatory/analgesic agents
HUP0302068A3 (en) 2000-07-20 2005-05-30 Lauras As Use of cox-2 inhibitors for treating or preventing immunodeficiency and pharmaceutical compositions containing them

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352832A (en) * 1992-12-18 1994-10-04 Schering Corporation Asymmetric process for preparing florfenicol, thiamphenicol chloramphenicol and oxazoline intermediates
US5393790A (en) * 1994-02-10 1995-02-28 G.D. Searle & Co. Substituted spiro compounds for the treatment of inflammation
UA57002C2 (en) * 1995-10-13 2003-06-16 Мерк Фросст Кенада Енд Ко./Мерк Фросст Кенада Енд Сі. (methylsulfonyl)phenyl-2-(5n)-furanon derivative, a pharmaceutical composition and a method for treatment
US5789413A (en) * 1996-02-01 1998-08-04 Merck Frosst Canada, Inc. Alkylated styrenes as prodrugs to COX-2 inhibitors

Also Published As

Publication number Publication date
EP1017687A1 (en) 2000-07-12
JP2001517661A (en) 2001-10-09
WO1999015513A1 (en) 1999-04-01
SK4202000A3 (en) 2000-10-09
EP1017687A4 (en) 2001-10-31
JP3516658B2 (en) 2004-04-05
EA002690B1 (en) 2002-08-29
CN1271352A (en) 2000-10-25
EA200000350A1 (en) 2000-10-30

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase