AU2023317864A1 - Intranasal administration of ngf for the treatment of sensorineural hearing loss - Google Patents
Intranasal administration of ngf for the treatment of sensorineural hearing loss Download PDFInfo
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- AU2023317864A1 AU2023317864A1 AU2023317864A AU2023317864A AU2023317864A1 AU 2023317864 A1 AU2023317864 A1 AU 2023317864A1 AU 2023317864 A AU2023317864 A AU 2023317864A AU 2023317864 A AU2023317864 A AU 2023317864A AU 2023317864 A1 AU2023317864 A1 AU 2023317864A1
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- ngf
- seq
- mutein
- treatment
- concentration
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Zoology (AREA)
- Psychology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP22188990.0A EP4316505A1 (en) | 2022-08-05 | 2022-08-05 | Intranasal administration of ngf for the treatment of sensorineural hearing loss |
| EP22188990.0 | 2022-08-05 | ||
| PCT/EP2023/071698 WO2024028487A1 (en) | 2022-08-05 | 2023-08-04 | Intranasal administration of ngf for the treatment of sensorineural hearing loss |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2023317864A1 true AU2023317864A1 (en) | 2025-02-13 |
Family
ID=82846594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2023317864A Pending AU2023317864A1 (en) | 2022-08-05 | 2023-08-04 | Intranasal administration of ngf for the treatment of sensorineural hearing loss |
Country Status (7)
| Country | Link |
|---|---|
| EP (2) | EP4316505A1 (cg-RX-API-DMAC10.html) |
| JP (1) | JP2025525989A (cg-RX-API-DMAC10.html) |
| CN (1) | CN119836297A (cg-RX-API-DMAC10.html) |
| AU (1) | AU2023317864A1 (cg-RX-API-DMAC10.html) |
| CA (1) | CA3263975A1 (cg-RX-API-DMAC10.html) |
| IL (1) | IL318657A (cg-RX-API-DMAC10.html) |
| WO (1) | WO2024028487A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4623927A1 (en) | 2024-03-27 | 2025-10-01 | Dompe' Farmaceutici SpA | Ngf for use in the prevention or treatment of motor impairment caused by neonatal hypoxic-ischemic encephalopathy |
| EP4659759A1 (en) * | 2024-06-04 | 2025-12-10 | Dompé farmaceutici SpA | Administration of ngf for the treatment of niemann-pick type c disease |
| WO2026022244A1 (en) | 2024-07-23 | 2026-01-29 | Chiesi Farmaceutici S.P.A. | A polypeptide for use in the therapeutic management of acute ischaemic stroke |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE257514T1 (de) | 1998-10-09 | 2004-01-15 | Scil Proteins Gmbh | Verfahren zur gewinnung von aktivem beta-ngf |
| ITRM20110390A1 (it) * | 2011-07-21 | 2013-01-22 | Eramo Alessandra D | Prodotto per stimolare la produzione endogena di mediatori dell'infiammazione. |
| ES2545701T3 (es) | 2011-12-19 | 2015-09-15 | Wacker Chemie Ag | Nuevos mutantes de proNGF y usos de los mismos en la producción de beta-NGF |
| US20190022101A1 (en) * | 2016-01-06 | 2019-01-24 | Massachusetts Eye And Ear Infirmary | Treating Cochlear Synaptopathy |
| WO2018140792A2 (en) * | 2017-01-27 | 2018-08-02 | Otonomy, Inc. | Neurotrophin mutants for treating hearing loss and other otic disorders |
| EP3406259A1 (en) * | 2017-05-24 | 2018-11-28 | Dompé farmaceutici S.p.A. | Neurotrophins for use in the treatment of hearing loss |
| WO2019207106A1 (en) | 2018-04-27 | 2019-10-31 | Chiesi Farmaceutici Spa | Production of nerve growth factor (ngf) and of muteins thereof |
| WO2022105847A1 (en) * | 2020-11-19 | 2022-05-27 | Staidson (Beijing) Biopharmaceuticals Co. , Ltd. | Long-acting nerve growth factor polypeptides and uses thereof |
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| EP4565255A1 (en) | 2025-06-11 |
| CA3263975A1 (en) | 2024-02-08 |
| EP4316505A1 (en) | 2024-02-07 |
| CN119836297A (zh) | 2025-04-15 |
| JP2025525989A (ja) | 2025-08-07 |
| WO2024028487A1 (en) | 2024-02-08 |
| IL318657A (en) | 2025-03-01 |
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