AU2022382406A1 - Engineered effector cells for trafficking of allogeneic cell therapies in solid tumors - Google Patents

Engineered effector cells for trafficking of allogeneic cell therapies in solid tumors Download PDF

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Publication number
AU2022382406A1
AU2022382406A1 AU2022382406A AU2022382406A AU2022382406A1 AU 2022382406 A1 AU2022382406 A1 AU 2022382406A1 AU 2022382406 A AU2022382406 A AU 2022382406A AU 2022382406 A AU2022382406 A AU 2022382406A AU 2022382406 A1 AU2022382406 A1 AU 2022382406A1
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cell
cells
car
receptor
derivative
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Martin HOSKING
Soheila SHIRINBAK
Bahram Valamehr
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Fate Therapeutics Inc
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Fate Therapeutics Inc
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    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61K40/00—Cellular immunotherapy
    • A61K40/50—Cellular immunotherapy characterised by the use of allogeneic cells
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    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
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AU2022382406A 2021-11-08 2022-11-07 Engineered effector cells for trafficking of allogeneic cell therapies in solid tumors Pending AU2022382406A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163277034P 2021-11-08 2021-11-08
US63/277,034 2021-11-08
US202263329203P 2022-04-08 2022-04-08
US63/329,203 2022-04-08
PCT/US2022/079412 WO2023081896A1 (en) 2021-11-08 2022-11-07 Engineered effector cells for trafficking of allogeneic cell therapies in solid tumors

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AU2022382406A1 true AU2022382406A1 (en) 2024-05-23

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AU2022382406A Pending AU2022382406A1 (en) 2021-11-08 2022-11-07 Engineered effector cells for trafficking of allogeneic cell therapies in solid tumors

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US (1) US20250009882A1 (https=)
EP (1) EP4430165A4 (https=)
JP (1) JP2024540237A (https=)
KR (1) KR20240099409A (https=)
AU (1) AU2022382406A1 (https=)
CA (1) CA3236260A1 (https=)
IL (1) IL312565A (https=)
WO (1) WO2023081896A1 (https=)

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Publication number Priority date Publication date Assignee Title
CN117343908B (zh) * 2023-12-05 2024-02-09 南京大学 一种通过真菌精准激活的car-t细胞、制备方法、应用及药物组合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021505131A (ja) * 2017-12-08 2021-02-18 フェイト セラピューティクス，インコーポレイテッド 増強されたｉＰＳＣ由来のエフェクター細胞を用いた免疫療法
US11987816B2 (en) * 2018-04-02 2024-05-21 Korea University Research And Business Foundation Composition for inducing dedifferentiation from somatic cells to induced pluripotent stem cells and method of inducing dedifferentiation using same
CN114258429A (zh) * 2019-07-17 2022-03-29 菲特治疗公司 免疫效应细胞工程化和其用途
US20250228943A1 (en) * 2022-04-08 2025-07-17 Fate Therapeutics, Inc. Cells having solid tumor targeting backbone and use thereof

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JP2024540237A (ja) 2024-10-31
EP4430165A1 (en) 2024-09-18
KR20240099409A (ko) 2024-06-28
IL312565A (en) 2024-07-01
WO2023081896A1 (en) 2023-05-11
US20250009882A1 (en) 2025-01-09
EP4430165A4 (en) 2025-12-03
CA3236260A1 (en) 2023-05-11

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