AU2022356377A1 - Novel substituted sulfonylurea compounds as inhibitors of interleukin-1 activity - Google Patents
Novel substituted sulfonylurea compounds as inhibitors of interleukin-1 activity Download PDFInfo
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- AU2022356377A1 AU2022356377A1 AU2022356377A AU2022356377A AU2022356377A1 AU 2022356377 A1 AU2022356377 A1 AU 2022356377A1 AU 2022356377 A AU2022356377 A AU 2022356377A AU 2022356377 A AU2022356377 A AU 2022356377A AU 2022356377 A1 AU2022356377 A1 AU 2022356377A1
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- 150000003839 salts Chemical class 0.000 claims description 39
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2021/121548 | 2021-09-29 | ||
| CN2021121548 | 2021-09-29 | ||
| PCT/US2022/077120 WO2023056264A1 (en) | 2021-09-29 | 2022-09-27 | Novel substituted sulfonylurea compounds as inhibitors of interleukin-1 activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2022356377A1 true AU2022356377A1 (en) | 2024-04-11 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| AU2022356377A Pending AU2022356377A1 (en) | 2021-09-29 | 2022-09-27 | Novel substituted sulfonylurea compounds as inhibitors of interleukin-1 activity |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20240400561A1 (https=) |
| EP (1) | EP4408843A1 (https=) |
| JP (1) | JP2024538602A (https=) |
| KR (1) | KR20240089127A (https=) |
| CN (1) | CN118251393A (https=) |
| AU (1) | AU2022356377A1 (https=) |
| CA (1) | CA3233673A1 (https=) |
| IL (1) | IL311784A (https=) |
| MX (1) | MX2024003948A (https=) |
| WO (1) | WO2023056264A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2025153532A1 (en) | 2024-01-16 | 2025-07-24 | NodThera Limited | Nlrp3 inhibitors and glp-1 agonists combination therapies |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US11465992B2 (en) * | 2017-07-07 | 2022-10-11 | Inflazome Limited | Sulfonamide carboxamide compounds |
| US11370776B2 (en) * | 2017-07-07 | 2022-06-28 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors |
| MX2020001776A (es) * | 2017-08-15 | 2020-03-24 | Inflazome Ltd | Sulfonilureas y sulfoniltioureas como inhibidores de nlrp3. |
| US11542255B2 (en) * | 2017-08-15 | 2023-01-03 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors |
| EP3668861A1 (en) * | 2017-08-15 | 2020-06-24 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
| KR20200087759A (ko) * | 2017-11-09 | 2020-07-21 | 인플라좀 리미티드 | 신규한 설폰아마이드 카복스아마이드 화합물 |
| GB201902327D0 (en) * | 2019-02-20 | 2019-04-03 | Inflazome Ltd | Novel compounds |
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2022
- 2022-09-27 JP JP2024519269A patent/JP2024538602A/ja active Pending
- 2022-09-27 KR KR1020247014041A patent/KR20240089127A/ko active Pending
- 2022-09-27 WO PCT/US2022/077120 patent/WO2023056264A1/en not_active Ceased
- 2022-09-27 MX MX2024003948A patent/MX2024003948A/es unknown
- 2022-09-27 CN CN202280075492.3A patent/CN118251393A/zh active Pending
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- 2022-09-27 EP EP22801649.9A patent/EP4408843A1/en active Pending
- 2022-09-27 US US18/696,901 patent/US20240400561A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL311784A (en) | 2024-05-01 |
| WO2023056264A1 (en) | 2023-04-06 |
| CN118251393A (zh) | 2024-06-25 |
| EP4408843A1 (en) | 2024-08-07 |
| JP2024538602A (ja) | 2024-10-23 |
| US20240400561A1 (en) | 2024-12-05 |
| KR20240089127A (ko) | 2024-06-20 |
| MX2024003948A (es) | 2024-06-28 |
| CA3233673A1 (en) | 2023-04-06 |
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