AU2021344091A1 - Methods of treating ribonucleotide reductase-related diseases with a ribonucleotide reductase inhibitor - Google Patents

Methods of treating ribonucleotide reductase-related diseases with a ribonucleotide reductase inhibitor Download PDF

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Publication number
AU2021344091A1
AU2021344091A1 AU2021344091A AU2021344091A AU2021344091A1 AU 2021344091 A1 AU2021344091 A1 AU 2021344091A1 AU 2021344091 A AU2021344091 A AU 2021344091A AU 2021344091 A AU2021344091 A AU 2021344091A AU 2021344091 A1 AU2021344091 A1 AU 2021344091A1
Authority
AU
Australia
Prior art keywords
week
salt
oxo
dimetylphenyl
oxadiazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2021344091A
Other languages
English (en)
Other versions
AU2021344091A9 (en
Inventor
Takuya Hoshino
Harold Keer
Aram Oganesian
Hiroyuki Ueno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiho Pharmaceutical Co Ltd
Astex Pharmaceuticals Inc
Original Assignee
Taiho Pharmaceutical Co Ltd
Astex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd, Astex Pharmaceuticals Inc filed Critical Taiho Pharmaceutical Co Ltd
Publication of AU2021344091A1 publication Critical patent/AU2021344091A1/en
Publication of AU2021344091A9 publication Critical patent/AU2021344091A9/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245Oxadiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2021344091A 2020-09-15 2021-09-15 Methods of treating ribonucleotide reductase-related diseases with a ribonucleotide reductase inhibitor Pending AU2021344091A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063078833P 2020-09-15 2020-09-15
US63/078,833 2020-09-15
PCT/JP2021/033854 WO2022059691A1 (en) 2020-09-15 2021-09-15 Methods of treating ribonucleotide reductase-related diseases with a ribonucleotide reductase inhibitor

Publications (2)

Publication Number Publication Date
AU2021344091A1 true AU2021344091A1 (en) 2023-05-25
AU2021344091A9 AU2021344091A9 (en) 2024-08-08

Family

ID=80776688

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2021344091A Pending AU2021344091A1 (en) 2020-09-15 2021-09-15 Methods of treating ribonucleotide reductase-related diseases with a ribonucleotide reductase inhibitor

Country Status (6)

Country Link
US (1) US20230338342A1 (https=)
EP (1) EP4213841A4 (https=)
JP (1) JP2023541430A (https=)
KR (1) KR20230067646A (https=)
AU (1) AU2021344091A1 (https=)
WO (1) WO2022059691A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025240847A1 (en) 2024-05-17 2025-11-20 Revolution Medicines, Inc. Ras inhibitors
US20250375445A1 (en) 2024-06-07 2025-12-11 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
WO2025265060A1 (en) 2024-06-21 2025-12-26 Revolution Medicines, Inc. Therapeutic compositions and methods for managing treatment-related effects
WO2026006747A1 (en) 2024-06-28 2026-01-02 Revolution Medicines, Inc. Ras inhibitors
WO2026015801A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015796A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015825A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Use of ras inhibitor for treating pancreatic cancer
WO2026015790A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026050446A1 (en) 2024-08-29 2026-03-05 Revolution Medicines, Inc. Ras inhibitors
WO2026072904A2 (en) 2024-09-26 2026-04-02 Revolution Medicines, Inc. Compositions and methods for treating lung cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130005678A1 (en) * 2010-03-30 2013-01-03 Clavis Pharma Asa Methods and Compositions for Treating or Ameliorating Cancer Using Gemcitabine-5'-Elaidate
US10889555B2 (en) * 2016-05-31 2021-01-12 Taiho Pharmaceutical Co., Ltd. Sulfonamide compound or salt thereof
US20200405697A1 (en) * 2017-11-29 2020-12-31 Taiho Pharmaceutical Co., Ltd. Antitumor Agent

Also Published As

Publication number Publication date
EP4213841A1 (en) 2023-07-26
WO2022059691A1 (en) 2022-03-24
JP2023541430A (ja) 2023-10-02
US20230338342A1 (en) 2023-10-26
AU2021344091A9 (en) 2024-08-08
TW202227059A (zh) 2022-07-16
KR20230067646A (ko) 2023-05-16
EP4213841A4 (en) 2024-07-24

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Legal Events

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SREP Specification republished