AU2020367945A1 - Anti-TIRC7 antigen binding proteins - Google Patents

Anti-TIRC7 antigen binding proteins Download PDF

Info

Publication number
AU2020367945A1
AU2020367945A1 AU2020367945A AU2020367945A AU2020367945A1 AU 2020367945 A1 AU2020367945 A1 AU 2020367945A1 AU 2020367945 A AU2020367945 A AU 2020367945A AU 2020367945 A AU2020367945 A AU 2020367945A AU 2020367945 A1 AU2020367945 A1 AU 2020367945A1
Authority
AU
Australia
Prior art keywords
abp
cell
antibody
tirc7
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2020367945A
Other languages
English (en)
Inventor
Nalan Utku
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nekonal SARL
Original Assignee
Nekonal SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nekonal SARL filed Critical Nekonal SARL
Publication of AU2020367945A1 publication Critical patent/AU2020367945A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74—Inducing cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2020367945A 2019-09-30 2020-09-30 Anti-TIRC7 antigen binding proteins Pending AU2020367945A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19200324 2019-09-30
EP19200324.2 2019-09-30
PCT/EP2020/077422 WO2021073877A2 (en) 2019-09-30 2020-09-30 Anti-tirc7 antigen binding proteins

Publications (1)

Publication Number Publication Date
AU2020367945A1 true AU2020367945A1 (en) 2022-05-12

Family

ID=68084722

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2020367945A Pending AU2020367945A1 (en) 2019-09-30 2020-09-30 Anti-TIRC7 antigen binding proteins

Country Status (6)

Country Link
US (2) US12497451B2 (https=)
EP (1) EP4041766A2 (https=)
JP (1) JP7691977B2 (https=)
AU (1) AU2020367945A1 (https=)
CA (1) CA3156134A1 (https=)
WO (1) WO2021073877A2 (https=)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
EP1400536A1 (en) 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
WO2003054018A2 (en) * 2001-12-21 2003-07-03 Genpat77 Pharmacogenetics Ag Anti-tirc7 antibodies in therapy of inflammatory diseases
US20060165684A1 (en) * 2001-12-21 2006-07-27 Nalan Utku Therapeutic anti-tirc7 antibodies for use in immune related and other diseases

Also Published As

Publication number Publication date
WO2021073877A3 (en) 2021-07-29
JP2023504974A (ja) 2023-02-08
CA3156134A1 (en) 2021-04-22
US20220363753A1 (en) 2022-11-17
WO2021073877A2 (en) 2021-04-22
EP4041766A2 (en) 2022-08-17
US12497451B2 (en) 2025-12-16
US20260062479A1 (en) 2026-03-05
JP7691977B2 (ja) 2025-06-12

Similar Documents

Publication Publication Date Title
JP7410143B2 (ja) 二重特異性抗体及びその用途
AU2020210635B2 (en) Antibodies against IL-7R alpha subunit and uses thereof
DK2536764T3 (en) ANTI-CD28 HUMANIZED ANTIBODIES
AU2018247270A1 (en) Anti-CTLA4 monoclonal antibody or antigen binding fragment thereof, medicinal composition and use
EP3192810A1 (en) Psma binding antibody and uses thereof
RU2770209C2 (ru) Терапевтические антитела против лиганда cd40
EA039594B1 (ru) Биспецифические конструкции антител к bcma и cd3, вовлекающие т-клетки
US20250197510A1 (en) Anti-FLT3 Antigen Binding Proteins
JP2017534267A (ja) イヌｐｄ−ｌ１と結合するｐｄ−ｌ１抗体
EP3288974B1 (en) Type iii secretion system targeting molecules
JP2026508244A (ja) 抗Ｎｅｃｔｉｎ－４抗体及びそれを含む多重特異性抗体
US12460010B2 (en) Antibodies that bind TNFRSF25
US20240141036A1 (en) Epitope of Regulatory T Cell Surface Antigen, and Antibody Specifically Binding Thereto
US20260062479A1 (en) Anti-tirc7 antigen binding proteins
EP3623383A1 (en) Improved bispecific flt3xcd3 antigen binding proteins
US20240158525A1 (en) Gitr antagonists and methods of using the same
CA3111462C (en) Improved anti-flt3 antigen binding proteins
RU2830982C2 (ru) Улучшенные анти-flt3 антигенсвязывающие белки
RU2811912C2 (ru) Антитела против альфа-субъединицы ил-7r и их применение
WO2026072951A2 (en) Bispecific antibodies that bind tnfrsf25 and αlpha4βeta7
WO2026072963A1 (en) Bispecific antibodies that bind tnfrsf25 and il-23/il-23r
HK1250991B (en) Type iii secretion system targeting molecules