AU2020315134A1 - Non-invasive method for the diagnosis or screening of colorectal cancer and/or pre-cancerous stage thereof - Google Patents

Non-invasive method for the diagnosis or screening of colorectal cancer and/or pre-cancerous stage thereof Download PDF

Info

Publication number
AU2020315134A1
AU2020315134A1 AU2020315134A AU2020315134A AU2020315134A1 AU 2020315134 A1 AU2020315134 A1 AU 2020315134A1 AU 2020315134 A AU2020315134 A AU 2020315134A AU 2020315134 A AU2020315134 A AU 2020315134A AU 2020315134 A1 AU2020315134 A1 AU 2020315134A1
Authority
AU
Australia
Prior art keywords
mir
colorectal cancer
expression level
determination
haemoglobin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2020315134A
Other languages
English (en)
Inventor
Antoni CASTELLS GARANGOU
Saray DURAN SANCHON
Meritxell GIRONELLA COS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitat de Barcelona UB
Hospital Clinic de Barcelona
Centro de Investigacion Biomedica en Red CIBER
Institut d'Investigacions Biomèdiques August Pi i Sunyer
Original Assignee
Universitat de Barcelona UB
Hospital Clinic de Barcelona
Centro de Investigacion Biomedica en Red CIBER
Institut d'Investigacions Biomèdiques August Pi i Sunyer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitat de Barcelona UB, Hospital Clinic de Barcelona, Centro de Investigacion Biomedica en Red CIBER, Institut d'Investigacions Biomèdiques August Pi i Sunyer filed Critical Universitat de Barcelona UB
Publication of AU2020315134A1 publication Critical patent/AU2020315134A1/en
Assigned to UNIVERSITAT DE BARCELONA, HOSPITAL CLÍNIC DE BARCELONA, INSTITUT D'INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER (IDIBAPS), CONSORCIO CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED reassignment UNIVERSITAT DE BARCELONA Request for Assignment Assignors: Consorcio Centro de Investigación Biomédica en Red, M.P., HOSPITAL CLÍNIC DE BARCELONA, INSTITUT D'INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER (IDIBAPS), UNIVERSITAT DE BARCELONA
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AU2020315134A 2019-07-15 2020-07-14 Non-invasive method for the diagnosis or screening of colorectal cancer and/or pre-cancerous stage thereof Pending AU2020315134A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19382597 2019-07-15
EP19382597.3 2019-07-15
PCT/EP2020/069918 WO2021009184A1 (en) 2019-07-15 2020-07-14 Non-invasive method for the diagnosis or screening of colorectal cancer and/or pre-cancerous stage thereof

Publications (1)

Publication Number Publication Date
AU2020315134A1 true AU2020315134A1 (en) 2022-02-03

Family

ID=67480120

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2020315134A Pending AU2020315134A1 (en) 2019-07-15 2020-07-14 Non-invasive method for the diagnosis or screening of colorectal cancer and/or pre-cancerous stage thereof

Country Status (5)

Country Link
US (1) US20220333205A1 (https=)
EP (1) EP3999663A1 (https=)
JP (1) JP7727970B2 (https=)
AU (1) AU2020315134A1 (https=)
WO (1) WO2021009184A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4130296A1 (en) * 2021-08-03 2023-02-08 Deutsches Krebsforschungszentrum - Stiftung des öffentlichen Rechts / Universität Heidelberg Cancer prediction
CN114107514A (zh) * 2022-01-27 2022-03-01 天津欧德莱生物医药科技有限公司 一种用于结直肠癌诊断的miRNA分子标志物及其试剂盒
CN116219019B (zh) * 2023-03-02 2026-01-27 圣湘生物科技股份有限公司 一种用于结直肠癌诊断的microRNA标志物组合物及检测试剂、检测试剂盒

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2919064B1 (fr) * 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage de l'apolipoproteine all pour le diagnostic in vitro du cancer colorectal
WO2009111643A2 (en) * 2008-03-06 2009-09-11 Asuragen, Inc. Microrna markers for recurrence of colorectal cancer
US9074206B2 (en) * 2008-11-13 2015-07-07 Fudan University Compositions and methods for micro-RNA expression profiling of colorectal cancer
US20120088687A1 (en) * 2010-10-08 2012-04-12 Baylor Research Institute MicroRNAs (miRNA) as Biomarkers for the Identification of Familial and Non-Familial Colorectal Cancer
NO3051026T3 (https=) * 2011-10-21 2018-07-28
PL418144A1 (pl) * 2016-07-29 2018-02-12 Gdański Uniwersytet Medyczny Nowy marker obecności mikroprzerzutów i podwyższonego ryzyka nawrotu raka jelita grubego, sposób wykrywania obecności mikroprzerzutów i podwyższonego ryzyka nawrotu raka jelita grubego oraz geny normalizacyjne do normalizacji wyników ekspresji miRNA w tkance raka jelita grubego

Also Published As

Publication number Publication date
JP7727970B2 (ja) 2025-08-22
US20220333205A1 (en) 2022-10-20
WO2021009184A1 (en) 2021-01-21
EP3999663A1 (en) 2022-05-25
JP2022541169A (ja) 2022-09-22

Similar Documents

Publication Publication Date Title
Duran-Sanchon et al. Identification and validation of microRNA profiles in fecal samples for detection of colorectal cancer
Duffy et al. Circulating tumor DNA (ctDNA) as a pan-cancer screening test: is it finally on the horizon?
ES2443230T3 (es) Nuevos marcadores para el cáncer
WO2019068082A1 (en) Dna methylation biomarkers for cancer diagnosing
CN103937888B (zh) 鉴别胃癌的血浆microRNA标志物的筛选与应用
ES3040741T3 (en) Methods of analyzing cell free nucleic acids and applications thereof
AU2020265027A1 (en) Microrna marker combination for diagnosing gastric cancer and diagnostic kit
JP7727970B2 (ja) 結腸直腸癌および／またはその前癌段階の診断またはスクリーニングのための非侵襲的方法
Mohamed et al. A panel of three microRNA signatures as a potential biomarker for CRC screening based on stages and functional prediction using bioinformatic analysis
CN116144782A (zh) 一种用于肺癌检测的组合标志物及其应用
CN114107498B (zh) 结直肠癌血液检测标记物及其应用
CN104630357A (zh) 一种与结直肠癌相关的血浆miRNA生物标志物及其应用
CN111321222A (zh) 用于结直肠癌无创诊断的血清piRNA标志物及检测试剂盒
WO2022023233A9 (en) Biomarkers for diagnosing and monitoring lung cancer
CN116083579B (zh) 用于非小细胞肺癌诊断的circRNA-miRNA-mRNA调控网络及其应用
US20220220562A1 (en) In vitro method for identifying colorectal adenomas or colorectal cancer
CN114402082B (zh) 用于结直肠癌或其癌前阶段的诊断或预后的体外方法
Chen et al. 146P A new biomarker of microbe: Akkermansia muciniphila in lung adenocarcinoma tissues may predict lymph node metastasis in lung adenocarcinoma
Gallardo-Gómez et al. Serum DNA methylome of the colorectal cancer serrated pathway
Yazdanpour et al. Non-invasive discrimination of adenocarcinoma and squamous cell carcinoma based on differential expression of miR-944 and miR-326 in sputum samples of lung cancer patients
Tran et al. Multimodal analysis of ctDNA methylation and fragmentomic profiles enhances detection of nonmetastatic colorectal cancer
Gallardo Gómez Desarrollo de biomarcadores de metilación no invasivos para el cribado de cáncer colorrectal
CN114875151A (zh) 血浆外泌体生物标志物在胃癌新辅助化疗敏感人群筛查或疗效预测中的应用
WO2026090778A1 (zh) 用于检测胃癌的标志物、试剂盒及其应用
CN116219007A (zh) 检测结直肠癌的生物标志物组及其应用

Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: UNIVERSITAT DE BARCELONA

Free format text: FORMER APPLICANT(S): HOSPITAL CLINIC DE BARCELONA; INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER (IDIBAPS); UNIVERSITAT DE BARCELONA; CONSORCIO CENTRO DE INVESTIGACION BIOMEDICA EN RED, M.P.

Owner name: HOSPITAL CLINIC DE BARCELONA

Free format text: FORMER APPLICANT(S): HOSPITAL CLINIC DE BARCELONA; INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER (IDIBAPS); UNIVERSITAT DE BARCELONA; CONSORCIO CENTRO DE INVESTIGACION BIOMEDICA EN RED, M.P.

Owner name: INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER (IDIBAPS)

Free format text: FORMER APPLICANT(S): HOSPITAL CLINIC DE BARCELONA; INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER (IDIBAPS); UNIVERSITAT DE BARCELONA; CONSORCIO CENTRO DE INVESTIGACION BIOMEDICA EN RED, M.P.

Owner name: CONSORCIO CENTRO DE INVESTIGACION BIOMEDICA EN RED

Free format text: FORMER APPLICANT(S): HOSPITAL CLINIC DE BARCELONA; INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER (IDIBAPS); UNIVERSITAT DE BARCELONA; CONSORCIO CENTRO DE INVESTIGACION BIOMEDICA EN RED, M.P.