AU2019255603B2 - Nerve block by electrical pulses at sub-threshold intensity - Google Patents

Nerve block by electrical pulses at sub-threshold intensity Download PDF

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Publication number
AU2019255603B2
AU2019255603B2 AU2019255603A AU2019255603A AU2019255603B2 AU 2019255603 B2 AU2019255603 B2 AU 2019255603B2 AU 2019255603 A AU2019255603 A AU 2019255603A AU 2019255603 A AU2019255603 A AU 2019255603A AU 2019255603 B2 AU2019255603 B2 AU 2019255603B2
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Australia
Prior art keywords
nerve
neuron
intensity
electrical stimulation
increased
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AU2019255603A
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AU2019255603A1 (en
Inventor
Changfeng Tai
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University of Pittsburgh
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University of Pittsburgh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36062—Spinal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36071—Pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/3615—Intensity
    • A61N1/36153—Voltage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/3615—Intensity
    • A61N1/36157—Current
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/3615—Intensity
    • A61N1/36164—Sub-threshold or non-excitatory signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36171—Frequency

Landscapes

  • Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Electrotherapy Devices (AREA)
  • Magnetic Treatment Devices (AREA)
AU2019255603A 2018-04-16 2019-04-15 Nerve block by electrical pulses at sub-threshold intensity Active AU2019255603B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862658147P 2018-04-16 2018-04-16
US62/658,147 2018-04-16
PCT/US2019/027471 WO2019204198A1 (en) 2018-04-16 2019-04-15 Nerve block by electrical pulses at sub-threshold intensity

Publications (2)

Publication Number Publication Date
AU2019255603A1 AU2019255603A1 (en) 2020-11-12
AU2019255603B2 true AU2019255603B2 (en) 2024-09-05

Family

ID=68239950

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AU2019255603A Active AU2019255603B2 (en) 2018-04-16 2019-04-15 Nerve block by electrical pulses at sub-threshold intensity

Country Status (8)

Country Link
US (3) US11865346B2 (enExample)
EP (1) EP3781252B1 (enExample)
JP (2) JP2021520942A (enExample)
KR (1) KR102873485B1 (enExample)
CN (1) CN112368047A (enExample)
AU (1) AU2019255603B2 (enExample)
CA (1) CA3097142A1 (enExample)
WO (1) WO2019204198A1 (enExample)

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US11413458B2 (en) 2011-05-19 2022-08-16 Neuros Medical, Inc. Nerve cuff electrode for neuromodulation in large human nerve trunks
AU2018385603B2 (en) 2017-12-13 2024-05-02 Neuros Medical, Inc. Nerve cuff deployment devices
WO2019199558A1 (en) 2018-04-09 2019-10-17 Neuros Medical, Inc. Apparatuses and methods for setting an electrical dose
CA3097142A1 (en) * 2018-04-16 2019-10-24 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Nerve block by electrical pulses at sub-threshold intensity
US12370079B2 (en) 2018-06-19 2025-07-29 Thermaquil, Inc. Apparatus and method for thermal blockade of nerves
US11878172B2 (en) 2020-02-11 2024-01-23 Neuros Medical, Inc. System and method for quantifying qualitative patient-reported data sets
CN115040230B (zh) * 2022-07-12 2024-04-23 上海宏桐实业有限公司 一种脉冲电场消融系统及电子设备
KR102682382B1 (ko) * 2023-11-28 2024-07-08 (주)리솔 통증 완화 장치 및 그 제어방법
CN118105624B (zh) * 2024-01-30 2024-09-13 上海诺诚电气股份有限公司 神经电刺激监测方法和系统

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US20040127953A1 (en) * 2001-02-20 2004-07-01 Kilgore Kevin L. Systems and methods for reversibly blocking nerve activity
US20100036454A1 (en) * 1998-06-03 2010-02-11 Ndi Medical, Llc. Systems and methods to place one or more leads in muscle for providing electrical stimulation to treat pain
US20130238049A1 (en) * 2009-03-20 2013-09-12 ElectroCore, LLC Non-invasive vagal nerve stimulation to treat disorders
US20150032181A1 (en) * 2013-07-26 2015-01-29 Boston Scientific Neuromodulation Corporation Systems and methods of providing modulation therapy without patient-perception of stimulation
US20170348540A1 (en) * 2016-06-02 2017-12-07 Boston Scientific Neuromodulation Corporation Priming-assisted neuromodulation therapy

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US7904176B2 (en) * 2006-09-07 2011-03-08 Bio Control Medical (B.C.M.) Ltd. Techniques for reducing pain associated with nerve stimulation
US7689277B2 (en) * 2002-03-22 2010-03-30 Leptos Biomedical, Inc. Neural stimulation for treatment of metabolic syndrome and type 2 diabetes
US20070025608A1 (en) * 2005-07-29 2007-02-01 Cyberonics, Inc. Enhancing intrinsic neural activity using a medical device to treat a patient
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US20040127953A1 (en) * 2001-02-20 2004-07-01 Kilgore Kevin L. Systems and methods for reversibly blocking nerve activity
US20130238049A1 (en) * 2009-03-20 2013-09-12 ElectroCore, LLC Non-invasive vagal nerve stimulation to treat disorders
US20150032181A1 (en) * 2013-07-26 2015-01-29 Boston Scientific Neuromodulation Corporation Systems and methods of providing modulation therapy without patient-perception of stimulation
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Also Published As

Publication number Publication date
EP3781252B1 (en) 2024-11-20
CA3097142A1 (en) 2019-10-24
WO2019204198A1 (en) 2019-10-24
AU2019255603A1 (en) 2020-11-12
JP2025013960A (ja) 2025-01-28
EP3781252A4 (en) 2021-12-15
US20240042211A1 (en) 2024-02-08
US11826572B2 (en) 2023-11-28
KR20210002535A (ko) 2021-01-08
CN112368047A (zh) 2021-02-12
EP3781252A1 (en) 2021-02-24
US20210283401A1 (en) 2021-09-16
KR102873485B1 (ko) 2025-10-20
JP2021520942A (ja) 2021-08-26
US20210106831A1 (en) 2021-04-15
US11865346B2 (en) 2024-01-09

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