AU2018294415A1 - Compositions and methods for inhibiting HMGB1 expression - Google Patents
Compositions and methods for inhibiting HMGB1 expression Download PDFInfo
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- AU2018294415A1 AU2018294415A1 AU2018294415A AU2018294415A AU2018294415A1 AU 2018294415 A1 AU2018294415 A1 AU 2018294415A1 AU 2018294415 A AU2018294415 A AU 2018294415A AU 2018294415 A AU2018294415 A AU 2018294415A AU 2018294415 A1 AU2018294415 A1 AU 2018294415A1
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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| PCT/US2018/040410 WO2019006375A1 (en) | 2017-06-29 | 2018-06-29 | COMPOSITIONS AND METHODS FOR INHIBITING HMGB1 EXPRESSION |
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| EP (1) | EP3645013A4 (https=) |
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| IL (2) | IL271680B (https=) |
| MX (1) | MX2020000154A (https=) |
| WO (1) | WO2019006375A1 (https=) |
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| IL271680B (en) | 2017-06-29 | 2022-09-01 | Dicerna Pharmaceuticals Inc | Compositions and methods for inhibiting hmgb1 expression |
| JP2021520355A (ja) * | 2018-04-13 | 2021-08-19 | ディセルナ ファーマシューティカルズ インコーポレイテッド | Ｔｍ上昇ヌクレオチドで修飾された二本鎖核酸阻害剤分子 |
| WO2020123083A1 (en) * | 2018-12-12 | 2020-06-18 | Dicerna Pharmaceuticals, Inc. | Double-stranded nucleic acid inhibitor molecules containing a triloop |
| SG11202106857VA (en) * | 2018-12-28 | 2021-07-29 | Dicerna Pharmaceuticals Inc | Compositions and methods for inhibiting hmgb1 expression |
| CA3209418A1 (en) * | 2021-04-14 | 2022-10-20 | Utsav SAXENA | Compositions and methods for modulating pnpla3 expression |
| WO2022223515A2 (en) * | 2021-04-19 | 2022-10-27 | Novo Nordisk A/S | Compositions and methods for inhibiting nuclear receptor subfamily 1 group h member 3 (nr1h3) expression |
| EP4392556A1 (en) * | 2021-08-25 | 2024-07-03 | Dicerna Pharmaceuticals, Inc. | Compositions and methods for inhibiting ?lpha-1 antitrypsin expression |
| JP2024543195A (ja) * | 2021-12-01 | 2024-11-19 | ディセルナ ファーマシューティカルズ インコーポレイテッド | Ａｐｏｃ３発現を調節するための組成物及び方法 |
| TWI868755B (zh) | 2022-06-24 | 2025-01-01 | 丹麥商諾佛 儂迪克股份有限公司 | 抑制跨膜絲胺酸蛋白酶６（ｔｍｐｒｓｓ６）表現的組成物及方法 |
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| US8178503B2 (en) * | 2006-03-03 | 2012-05-15 | International Business Machines Corporation | Ribonucleic acid interference molecules and binding sites derived by analyzing intergenic and intronic regions of genomes |
| WO2009099991A2 (en) * | 2008-01-31 | 2009-08-13 | The Brigham And Women's Hospital, Inc. | Treatment of cancer |
| DK2341943T3 (en) * | 2008-09-22 | 2019-02-25 | Dicerna Pharmaceuticals Inc | COMPOSITIONS AND METHODS OF SPECIFIC INHIBITION OF DSRNA REPRINT WITH MODIFICATIONS |
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| WO2014028494A1 (en) * | 2012-08-13 | 2014-02-20 | The Regents Of The University Of California | Detecting and treating liver damage |
| AU2015330670B2 (en) * | 2014-10-10 | 2022-01-06 | Novo Nordisk Health Care Ag | Therapeutic inhibition of lactate dehydrogenase and agents therefor |
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| CN106244589A (zh) * | 2016-08-01 | 2016-12-21 | 中国人民解放军第四军医大学 | 靶向hmgb1基因的rna干扰片段及其应用 |
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- 2018-06-29 IL IL295086A patent/IL295086A/en unknown
- 2018-06-29 CN CN201880056295.0A patent/CN111050776A/zh active Pending
- 2018-06-29 US US16/024,355 patent/US10675295B2/en active Active
- 2018-06-29 CA CA3068630A patent/CA3068630A1/en active Pending
- 2018-06-29 EP EP18824412.3A patent/EP3645013A4/en active Pending
- 2018-06-29 JP JP2019572382A patent/JP2020529197A/ja active Pending
-
2020
- 2020-04-30 US US16/863,081 patent/US11478501B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3645013A4 (en) | 2021-07-21 |
| US10675295B2 (en) | 2020-06-09 |
| IL271680A (en) | 2020-02-27 |
| EP3645013A1 (en) | 2020-05-06 |
| IL295086A (en) | 2022-09-01 |
| CA3068630A1 (en) | 2019-01-03 |
| US11478501B2 (en) | 2022-10-25 |
| US20190000870A1 (en) | 2019-01-03 |
| JP2020529197A (ja) | 2020-10-08 |
| KR20200023427A (ko) | 2020-03-04 |
| MX2020000154A (es) | 2020-07-22 |
| CN111050776A (zh) | 2020-04-21 |
| US20200297754A1 (en) | 2020-09-24 |
| WO2019006375A1 (en) | 2019-01-03 |
| IL271680B (en) | 2022-09-01 |
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| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |