AU2017363204B2 - Polynucleotide libraries having controlled stoichiometry and synthesis thereof - Google Patents

Polynucleotide libraries having controlled stoichiometry and synthesis thereof Download PDF

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Publication number
AU2017363204B2
AU2017363204B2 AU2017363204A AU2017363204A AU2017363204B2 AU 2017363204 B2 AU2017363204 B2 AU 2017363204B2 AU 2017363204 A AU2017363204 A AU 2017363204A AU 2017363204 A AU2017363204 A AU 2017363204A AU 2017363204 B2 AU2017363204 B2 AU 2017363204B2
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AU
Australia
Prior art keywords
polynucleotide
polynucleotides
percent
library
instances
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Ceased
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AU2017363204A
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AU2017363204A1 (en
Inventor
Siyuan CHEN
Ramsey Ibrahim Zeitoun
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Twist Bioscience Corp
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Twist Bioscience Corp
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Publication of AU2017363204A1 publication Critical patent/AU2017363204A1/en
Application granted granted Critical
Publication of AU2017363204B2 publication Critical patent/AU2017363204B2/en
Priority to AU2023200850A priority Critical patent/AU2023200850A1/en
Ceased legal-status Critical Current
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    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2017363204A 2016-11-18 2017-11-17 Polynucleotide libraries having controlled stoichiometry and synthesis thereof Ceased AU2017363204B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2023200850A AU2023200850A1 (en) 2016-11-18 2023-02-15 Polynucleotide libraries having controlled stoichiometry and synthesis thereof

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662424302P 2016-11-18 2016-11-18
US62/424,302 2016-11-18
US201762548307P 2017-08-21 2017-08-21
US62/548,307 2017-08-21
US201762558666P 2017-09-14 2017-09-14
US62/558,666 2017-09-14
PCT/US2017/062391 WO2018094263A1 (en) 2016-11-18 2017-11-17 Polynucleotide libraries having controlled stoichiometry and synthesis thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2023200850A Division AU2023200850A1 (en) 2016-11-18 2023-02-15 Polynucleotide libraries having controlled stoichiometry and synthesis thereof

Publications (2)

Publication Number Publication Date
AU2017363204A1 AU2017363204A1 (en) 2019-07-04
AU2017363204B2 true AU2017363204B2 (en) 2022-12-08

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
AU2017363204A Ceased AU2017363204B2 (en) 2016-11-18 2017-11-17 Polynucleotide libraries having controlled stoichiometry and synthesis thereof
AU2023200850A Abandoned AU2023200850A1 (en) 2016-11-18 2023-02-15 Polynucleotide libraries having controlled stoichiometry and synthesis thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2023200850A Abandoned AU2023200850A1 (en) 2016-11-18 2023-02-15 Polynucleotide libraries having controlled stoichiometry and synthesis thereof

Country Status (10)

Country Link
US (2) US20180142289A1 (OSRAM)
EP (1) EP3541973B1 (OSRAM)
JP (3) JP2020504709A (OSRAM)
KR (1) KR102569164B1 (OSRAM)
CN (1) CN110382752A (OSRAM)
AU (2) AU2017363204B2 (OSRAM)
CA (1) CA3044057A1 (OSRAM)
GB (1) GB2572877A (OSRAM)
IL (2) IL266681B2 (OSRAM)
WO (1) WO2018094263A1 (OSRAM)

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WO2016126882A1 (en) 2015-02-04 2016-08-11 Twist Bioscience Corporation Methods and devices for de novo oligonucleic acid assembly
US9981239B2 (en) 2015-04-21 2018-05-29 Twist Bioscience Corporation Devices and methods for oligonucleic acid library synthesis
HK1258869A1 (zh) 2015-09-18 2019-11-22 Twist Bioscience Corporation 寡核酸变体文库及其合成
CN108698012A (zh) 2015-09-22 2018-10-23 特韦斯特生物科学公司 用于核酸合成的柔性基底
US9895673B2 (en) 2015-12-01 2018-02-20 Twist Bioscience Corporation Functionalized surfaces and preparation thereof
ES2956757T3 (es) 2016-05-02 2023-12-27 Becton Dickinson Co Codificación con códigos de barras moleculares precisa
SG11201901563UA (en) 2016-08-22 2019-03-28 Twist Bioscience Corp De novo synthesized nucleic acid libraries
US10417457B2 (en) 2016-09-21 2019-09-17 Twist Bioscience Corporation Nucleic acid based data storage
WO2018094263A1 (en) * 2016-11-18 2018-05-24 Twist Bioscience Corporation Polynucleotide libraries having controlled stoichiometry and synthesis thereof
AU2017378492B2 (en) 2016-12-16 2022-06-16 Twist Bioscience Corporation Variant libraries of the immunological synapse and synthesis thereof
US11550939B2 (en) 2017-02-22 2023-01-10 Twist Bioscience Corporation Nucleic acid based data storage using enzymatic bioencryption
EP3595674A4 (en) 2017-03-15 2020-12-16 Twist Bioscience Corporation BANKS OF VARIANTS OF IMMUNOLOGICAL SYNAPSE AND THEIR SYNTHESIS
WO2018231864A1 (en) 2017-06-12 2018-12-20 Twist Bioscience Corporation Methods for seamless nucleic acid assembly
IL271205B2 (en) 2017-06-12 2025-02-01 Twist Bioscience Corp Methods for assembling continuous nucleic acids
GB2581620A (en) 2017-09-11 2020-08-26 Twist Bioscience Corp GPCR binding proteins and synthesis thereof
CA3079613A1 (en) 2017-10-20 2019-04-25 Twist Bioscience Corporation Heated nanowells for polynucleotide synthesis
GB2585506A (en) 2018-01-04 2021-01-13 Twist Bioscience Corp DNA-based digital information storage
CA3100739A1 (en) 2018-05-18 2019-11-21 Twist Bioscience Corporation Polynucleotides, reagents, and methods for nucleic acid hybridization
EP3902816A4 (en) 2018-12-26 2022-09-14 Twist Bioscience Corporation HIGHLY ACCURATE POLYNUCLEOTIDE DE NOVO SYNTHESIS
JP2022521551A (ja) 2019-02-26 2022-04-08 ツイスト バイオサイエンス コーポレーション Ｇｌｐ１受容体の変異体核酸ライブラリ
AU2020227802A1 (en) 2019-02-26 2021-10-14 Twist Bioscience Corporation Variant nucleic acid libraries for antibody optimization
AU2020298294A1 (en) 2019-06-21 2022-02-17 Twist Bioscience Corporation Barcode-based nucleic acid sequence assembly
US12091777B2 (en) 2019-09-23 2024-09-17 Twist Bioscience Corporation Variant nucleic acid libraries for CRTH2
EP4034564A4 (en) 2019-09-23 2023-12-13 Twist Bioscience Corporation VARIANT NUCLEIC ACID LIBRARIES FOR SINGLE-DOMAIN ANTIBODIES
WO2021092244A1 (en) * 2019-11-06 2021-05-14 Adaptive Biotechnologies Corporation Synthetic strands for nucleic acid sequencing and related methods and systems
CN110853708B (zh) * 2019-11-13 2022-03-08 上海仁东医学检验所有限公司 用于hla分型的核酸捕获探针的设计方法
EP4142784A4 (en) 2020-04-27 2024-12-18 Twist Bioscience Corporation VARIANT NUCLEIC ACID BANKS FOR CORONAVIRUS
EP4150110A4 (en) * 2020-05-11 2024-06-26 Personal Genome Diagnostics Inc. SELECTIVE CAPTURE OF TARGET DNA SEQUENCES
JP2023528003A (ja) * 2020-05-28 2023-07-03 イルミナ インコーポレイテッド 異なる特徴を有するポリヌクレオチドのコピーの比較
AU2021331088A1 (en) 2020-08-26 2023-05-04 Twist Bioscience Corporation Methods and compositions relating to glp1r variants
WO2022086866A1 (en) 2020-10-19 2022-04-28 Twist Bioscience Corporation Methods of synthesizing oligonucleotides using tethered nucleotides
WO2022159620A1 (en) 2021-01-21 2022-07-28 Twist Bioscience Corporation Methods and compositions relating to adenosine receptors
BE1029144B1 (fr) * 2021-02-25 2022-09-20 Oncodna Méthode de caracterisation d'une tumeur à l'aide d'un séquençage ciblé
US12258406B2 (en) 2021-03-24 2025-03-25 Twist Bioscience Corporation Antibodies that bind CD3 Epsilon
WO2022271884A2 (en) 2021-06-22 2022-12-29 Twist Bioscience Corporation Methods and compositions relating to covid antibody epitopes
WO2023091614A2 (en) 2021-11-18 2023-05-25 Twist Bioscience Corporation Dickkopf-1 variant antibodies and methods of use
US12325739B2 (en) 2022-01-03 2025-06-10 Twist Bioscience Corporation Bispecific SARS-CoV-2 antibodies and methods of use
CN116417071A (zh) * 2023-04-07 2023-07-11 祥符实验室 一种dna数据存储的选择性访问方法

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Also Published As

Publication number Publication date
IL266681B2 (en) 2025-01-01
US20180142289A1 (en) 2018-05-24
GB2572877A (en) 2019-10-16
US20210348220A1 (en) 2021-11-11
EP3541973B1 (en) 2024-03-27
WO2018094263A1 (en) 2018-05-24
AU2023200850A1 (en) 2023-03-16
KR102569164B1 (ko) 2023-08-21
CA3044057A1 (en) 2018-05-24
JP2020504709A (ja) 2020-02-13
JP2023017863A (ja) 2023-02-07
IL314890A (en) 2024-10-01
KR20190093585A (ko) 2019-08-09
CN110382752A (zh) 2019-10-25
JP2025028854A (ja) 2025-03-05
IL266681B1 (en) 2024-09-01
EP3541973A4 (en) 2020-07-29
GB201908719D0 (en) 2019-07-31
EP3541973A1 (en) 2019-09-25
IL266681A (en) 2019-07-31
AU2017363204A1 (en) 2019-07-04

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MK14 Patent ceased section 143(a) (annual fees not paid) or expired