AU2017285496B2 - Methods and system for epigenetic analysis - Google Patents

Methods and system for epigenetic analysis Download PDF

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Publication number
AU2017285496B2
AU2017285496B2 AU2017285496A AU2017285496A AU2017285496B2 AU 2017285496 B2 AU2017285496 B2 AU 2017285496B2 AU 2017285496 A AU2017285496 A AU 2017285496A AU 2017285496 A AU2017285496 A AU 2017285496A AU 2017285496 B2 AU2017285496 B2 AU 2017285496B2
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methylation
genomic
genome
regions
pel
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AU2017285496A1 (en
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Andrew P. Feinberg
John GOUTSIAS
William G. Jenkinson
Elisabet PUJADAS
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Johns Hopkins University
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Johns Hopkins University
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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/30—Detection of binding sites or motifs
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Data Mining & Analysis (AREA)
  • Bioethics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Artificial Intelligence (AREA)
  • Databases & Information Systems (AREA)
  • Epidemiology (AREA)
  • Evolutionary Computation (AREA)
  • Public Health (AREA)
  • Software Systems (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
AU2017285496A 2016-06-16 2017-06-16 Methods and system for epigenetic analysis Active AU2017285496B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662351056P 2016-06-16 2016-06-16
US62/351,056 2016-06-16
PCT/US2017/037900 WO2017218908A2 (en) 2016-06-16 2017-06-16 Methods and system for epigenetic analysis

Publications (2)

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AU2017285496A1 AU2017285496A1 (en) 2019-01-24
AU2017285496B2 true AU2017285496B2 (en) 2023-02-23

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AU2017285496A Active AU2017285496B2 (en) 2016-06-16 2017-06-16 Methods and system for epigenetic analysis

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US (1) US20220076779A1 (enExample)
EP (1) EP3472358B1 (enExample)
JP (1) JP7066643B2 (enExample)
AU (1) AU2017285496B2 (enExample)
ES (1) ES2897550T3 (enExample)
WO (1) WO2017218908A2 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11821027B2 (en) 2017-01-10 2023-11-21 Juno Therapeutics, Inc. Epigenetic analysis of cell therapy and related methods
CN110853706B (zh) * 2018-08-01 2022-07-22 中国科学院深圳先进技术研究院 一种整合表观遗传组学的肿瘤克隆组成构建方法及系统
CN109213833A (zh) * 2018-09-10 2019-01-15 成都四方伟业软件股份有限公司 二分类模型训练方法、数据分类方法及对应装置
CN110428319B (zh) * 2019-08-05 2021-04-27 深圳乐信软件技术有限公司 一种数据比对平台、方法、设备和存储介质
US11795495B1 (en) * 2019-10-02 2023-10-24 FOXO Labs Inc. Machine learned epigenetic status estimator
US11887698B2 (en) 2020-01-08 2024-01-30 Samsung Electronics Co., Ltd. Method and electronic device for building comprehensive genome scale metabolic model
CN112102878B (zh) * 2020-09-16 2024-01-26 张云鹏 一种LncRNA学习系统
CN114480655B (zh) * 2022-03-03 2024-07-16 北京起源聚禾生物科技有限公司 Dna甲基化标志物组合及应用、卵巢癌早期检测引物探针及试剂盒
EP4265738A4 (en) * 2022-03-03 2025-05-07 Beijing OriginPoly Bio-Tec Co., Ltd. Combination of DNA methylation markers and their use, primers, probes and kit for the early detection of ovarian cancer
CN115831217A (zh) * 2022-11-23 2023-03-21 四川大学 基于多模态融合的染色质拓扑关联结构域边界预测方法
WO2024137407A1 (en) * 2022-12-21 2024-06-27 The Johns Hopkins University Methods and targets of dna methylation entropy
WO2024173655A1 (en) * 2023-02-16 2024-08-22 Foundation Medicine, Inc. Classification of samples based on methylation analysis of dna fragments
CN116642819B (zh) * 2023-07-19 2023-10-10 江苏得康生物科技有限公司 细胞群的识别方法及其装置

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US5695934A (en) 1994-10-13 1997-12-09 Lynx Therapeutics, Inc. Massively parallel sequencing of sorted polynucleotides
US5888737A (en) 1997-04-15 1999-03-30 Lynx Therapeutics, Inc. Adaptor-based sequence analysis
GB0507835D0 (en) 2005-04-18 2005-05-25 Solexa Ltd Method and device for nucleic acid sequencing using a planar wave guide
US7514952B2 (en) 2005-06-29 2009-04-07 Altera Corporation I/O circuitry for reducing ground bounce and VCC sag in integrated circuit devices
SG170802A1 (en) 2006-03-31 2011-05-30 Solexa Inc Systems and devices for sequence by synthesis analysis
US8497066B2 (en) * 2008-12-04 2013-07-30 Rush University Medical Center DNA methylation based test for monitoring efficacy of treatment
AU2012253414B2 (en) * 2011-05-12 2016-03-17 The Johns Hopkins University Method of detecting cancer through generalized loss of stability of epigenetic domains, and compositions thereof
FI4056712T3 (fi) * 2012-09-20 2024-08-29 Univ Hong Kong Chinese Kasvaimen metyloomin nonivasiivinen määrittäminen plasmasta

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Kim KY, et al. PLoS computational biology. 2007 Mar;3(3):e60. *
Lapidus S, et al. 2008 Apr 22;105(16):6039-44. *

Also Published As

Publication number Publication date
EP3472358A2 (en) 2019-04-24
JP7066643B2 (ja) 2022-05-13
WO2017218908A2 (en) 2017-12-21
JP2019522285A (ja) 2019-08-08
EP3472358A4 (en) 2020-02-26
AU2017285496A1 (en) 2019-01-24
EP3472358B1 (en) 2021-08-18
ES2897550T3 (es) 2022-03-01
US20220076779A1 (en) 2022-03-10
WO2017218908A3 (en) 2018-01-18

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