AU2016347631B2 - Methods and systems for analyzing tissue quality using mid-infrared spectroscopy - Google Patents

Methods and systems for analyzing tissue quality using mid-infrared spectroscopy Download PDF

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Publication number
AU2016347631B2
AU2016347631B2 AU2016347631A AU2016347631A AU2016347631B2 AU 2016347631 B2 AU2016347631 B2 AU 2016347631B2 AU 2016347631 A AU2016347631 A AU 2016347631A AU 2016347631 A AU2016347631 A AU 2016347631A AU 2016347631 B2 AU2016347631 B2 AU 2016347631B2
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Australia
Prior art keywords
sample
fixation
spectrum
fixed
quality
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AU2016347631A
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AU2016347631A1 (en
Inventor
Daniel Bauer
David Chafin
Niels KROEGER-LUI
Michael Otter
Wolfgang Petrich
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F Hoffmann La Roche AG
Ventana Medical Systems Inc
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F Hoffmann La Roche AG
Ventana Medical Systems Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/39—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using tunable lasers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N2001/305—Fixative compositions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/39—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using tunable lasers
    • G01N2021/396—Type of laser source
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N2021/757—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated using immobilised reagents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/129—Using chemometrical methods

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  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU2016347631A 2015-10-28 2016-10-28 Methods and systems for analyzing tissue quality using mid-infrared spectroscopy Active AU2016347631B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562247609P 2015-10-28 2015-10-28
US62/247,609 2015-10-28
PCT/EP2016/076130 WO2017072320A1 (en) 2015-10-28 2016-10-28 Methods and systems for analyzing tissue quality using mid-infrared spectroscopy

Publications (2)

Publication Number Publication Date
AU2016347631A1 AU2016347631A1 (en) 2018-04-26
AU2016347631B2 true AU2016347631B2 (en) 2019-03-28

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU2016347631A Active AU2016347631B2 (en) 2015-10-28 2016-10-28 Methods and systems for analyzing tissue quality using mid-infrared spectroscopy

Country Status (6)

Country Link
US (1) US20190369017A1 (cg-RX-API-DMAC10.html)
EP (1) EP3368885B1 (cg-RX-API-DMAC10.html)
JP (1) JP6676160B2 (cg-RX-API-DMAC10.html)
AU (1) AU2016347631B2 (cg-RX-API-DMAC10.html)
CA (1) CA3001763C (cg-RX-API-DMAC10.html)
WO (1) WO2017072320A1 (cg-RX-API-DMAC10.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3792618B1 (en) 2018-05-09 2022-08-24 National Institutes for Quantum Science and Technology Tissue identifying device, tissue identifying system, tissue identifying method, inspecting method, endoscope system, tissue identifying program, and recording medium
WO2020022394A1 (en) * 2018-07-24 2020-01-30 Sony Corporation Information processing apparatus and microscope for separating the fluorescence of a fluorescent reageant from the autofluorescence of a specimen
WO2021037875A1 (en) 2019-08-28 2021-03-04 Ventana Medical Systems, Inc. Systems and methods for assessing specimen fixation duration and quality using vibrational spectroscopy
JP7644750B2 (ja) * 2019-08-28 2025-03-12 ベンタナ メディカル システムズ， インコーポレイテッド 振動分光法による抗原回収および標的回収進行量の評価
EP4022286A1 (en) * 2019-08-28 2022-07-06 Ventana Medical Systems, Inc. Label-free assessment of biomarker expression with vibrational spectroscopy
US11460400B2 (en) * 2020-07-07 2022-10-04 Sakura Finetek U.S.A., Inc. Use of IR spectroscopy to evaluate penetration of reagents into biological specimen
CN113030007B (zh) * 2021-02-10 2023-04-18 河南中烟工业有限责任公司 基于相似度学习算法快速检验烟用香精质量稳定性的方法
AU2022396109B2 (en) 2021-11-23 2026-06-04 Agilent Technologies, Inc. Digital analysis of preanalytical factors in tissues used for histological staining
EP4762536A1 (en) * 2023-08-16 2026-06-24 Ventana Medical Systems, Inc. Deep learning model to determine a fixation status of a morphologically stained biological specimen
CN119360129B (zh) * 2024-12-23 2025-03-21 浙江省测绘科学技术研究院 页岩油气井场分类方法和页岩油气开发活动监测方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011163624A1 (en) * 2010-06-25 2011-12-29 Cellmark Theranostics, Llc Method for analyzing biological specimens by spectral imaging
US20120270293A1 (en) * 2009-12-07 2012-10-25 Wei-Sing Chu Standardization of tissue specimen preservation by ultrasound and temperature control

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040253649A1 (en) * 1998-10-21 2004-12-16 Smith Steven J. Protein quantitation with cell imaging densitometry
US20010055799A1 (en) * 1998-12-15 2001-12-27 David Baunoch Method and apparatus for automated reprocessing of tissue samples
US20060249668A1 (en) * 2005-05-05 2006-11-09 Palo Alto Research Center Incorporated Automatic detection of quality spectra
CA2604317C (en) * 2007-08-06 2017-02-28 Historx, Inc. Methods and system for validating sample images for quantitative immunoassays

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120270293A1 (en) * 2009-12-07 2012-10-25 Wei-Sing Chu Standardization of tissue specimen preservation by ultrasound and temperature control
WO2011163624A1 (en) * 2010-06-25 2011-12-29 Cellmark Theranostics, Llc Method for analyzing biological specimens by spectral imaging

Also Published As

Publication number Publication date
US20190369017A1 (en) 2019-12-05
AU2016347631A1 (en) 2018-04-26
JP6676160B2 (ja) 2020-04-08
EP3368885A1 (en) 2018-09-05
EP3368885B1 (en) 2020-06-03
WO2017072320A1 (en) 2017-05-04
CA3001763C (en) 2020-10-27
JP2018532116A (ja) 2018-11-01
CA3001763A1 (en) 2017-05-04

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