AU2016265981B2 - Urea based skin treatment - Google Patents
Urea based skin treatment Download PDFInfo
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- AU2016265981B2 AU2016265981B2 AU2016265981A AU2016265981A AU2016265981B2 AU 2016265981 B2 AU2016265981 B2 AU 2016265981B2 AU 2016265981 A AU2016265981 A AU 2016265981A AU 2016265981 A AU2016265981 A AU 2016265981A AU 2016265981 B2 AU2016265981 B2 AU 2016265981B2
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- formulation
- urea
- cracking
- human skin
- film forming
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Abstract
A topical formulation for treating human skin is provided. The formulation having about 25% to about 35% urea by weight, film forming polymer, humectant, preservative, and 5 water. The above ingredients being combined such that the preservative protects the formulation against bacterial invasion, the humectant assists the formulation to retain water, and the water and film forming polymer enable the urea to be applied to human skin such that the urea sits on the skin as a stable film and is gradually absorbed into the skin to alleviate dryness or cracking, the film being substantially waterproof.
Description
COMPLETE SPECIFICATION
TITLE
Urea based skin treatment.
FIELD OF INVENTION
A preferred form of this invention relates to a urea based treatment for human skin, particularly for one’s feet, and especially, but not necessarily, the heels.
BACKGROUND
Many people suffer from dry skin at their feet. In some cases, the skin may flake off or crack. It is known to apply urea based heel balms to the feet as it is thought this helps the skin to retain a healthy amount of water. Some known products rely on heavy oily emulsions to get the urea into the skin, but a downside is that they can be messy and may cause staining of bed linen, etc. They can also make the feet undesirably slippery, which may present a safety risk. It is an object of a preferred embodiment of the invention to go at least some way towards addressing at least some of these shortcomings. While this object applies to the preferred embodiment, it should be understood that the object of the invention per se is simply to provide the public with a useful choice. Therefore, any objects applicable to the preferred embodiment should not be taken as a limitation on the scope of the claims to protection set out later in this document.
The term “comprises” or derivatives of this should not be interpreted as limiting. For example, if used in relation to a combination of features it should be taken to indicate that optionally, but not necessarily, there may be additional features that have not been mentioned.
SUMMARY OF INVENTION
According to one aspect of the invention there is provided a topical formulation for treating human skin, having:
• about 25% to about 35% urea by weight;
• film forming polymer;
• humectant;
• preservative; and
2016265981 29 Nov 2016 • water the above ingredients being combined such that the preservative protects the formulation against bacterial invasion, the humectant assists the formulation to retain water, and the water and film forming polymer enable the urea to be applied to human skin such that the urea sits on the skin as a stable film and is gradually absorbed into the skin to alleviate dryness or cracking, the film being substantially waterproof.
Optionally the formulation has about 30% urea, by weight.
Optionally the formulation having 25% to 35% urea, by weight.
Optionally the formulation having 30% urea, by weight.
Optionally the film forming polymer comprises a urethane polymer.
Optionally the film forming polymer comprises PPG-17/IDPI/DMPA copolymer.
Optionally the humectant comprises glycerine.
Optionally the preservative comprises one or more of phenoxyethanol, methyl paraben, ethyl paraben, propyl paraben and butyl paraben, and preferably a combination of all of these.
Optionally the preservative comprises Salichem (phenoxyethanol and methylparaben and ethylparaben and propylparaben and butylparaben) preservative or Phenonip (phenoxyethanol and methylparaben and ethylparaben and propylparaben and butylparaben and isobutylparaben) preservative.
According to a broader aspect of the invention, there is provided topical formulation for treating human skin, having:
• about 25% to about 35% urea, by weight;
• film forming polymer; and • water the above ingredients being combined such that the water and film forming polymer enable the urea to be applied to human skin such that the urea sits on the skin as a
2016265981 29 Nov 2016 stable film and is gradually absorbed into the skin to alleviate dryness or cracking, the file being substantially waterproof.
According to another aspect of the invention, there is provided use of:
• about 25% to about 35% urea, by weight;
• film forming polymer;
• humectant;
• preservative; and • water in the preparation of a topical formulation for treating human skin such that the urea site on the skin as a stable film and is gradually absorbed into the skin to alleviate dryness or cracking and wherein the film is substantially waterproof, the preservative protects the formulation against bacterial invasion, the humectant assists the formulation to retain water, and the water and film forming polymer enable the urea to be applied to the skin.
In broad terms in another aspect the invention comprises a method of treating dryness or cracking in human skin comprising applying a formulation to the skin, the formulation having:
• about 25% to about 35% urea, by weight;
• film forming polymer;
• humectant;
• preservative; and • water the above ingredients being combined such that the preservative protects the formulation against bacterial invasion, the humectant assists the formulation to retain water, and the water and film forming polymer enable the urea to be applied to human skin such that the urea sits on the skin as a stable film and is gradually absorbed into the skin to alleviate dryness or cracking, the film being substantially waterproof.
Optionally the formulation has about 30% urea, by weight.
Optionally the formulation has 30% urea, by weight.
Optionally the formulation has 25% to 35% urea by weight.
2016265981 29 Nov 2016
Optionally the film forming polymer of the formulation comprises a urethane polymer.
Optionally the film forming polymer of the formulation comprises PPG-17/IPDI/DMPA 5 copolymer.
Optionally the humectant of the formulation comprises glycerine.
Optionally the preservative of the formulation comprises one or more of 10 phenoxyethanol, methyl paraben, ethyl paraben, propyl paraben and butyl paraben, and preferably a combination of all of these.
DETAILED DESCRIPTION
According to a preferred embodiment of the invention a topical formulation for heel skin 15 is prepared from a mixture of the following ingredients:
Ingredient | Amount (grams) | Function |
Urea | 300 | therapeutic agent |
water | 603 | Solvent |
Avalure 450 polymer (PPG- 17/IPDI/DMPA copolymer) | 45 | Film forming polymer |
Glycerine | 50 | humectant |
Salichem (phenoxyethanol and methylparaben and ethylparaben and propylparaben and butylparaben) preservative or Phe no nip (phenoxyethanol and methylparaben and ethylparaben and propylparaben and butylparaben and | 2 | preservative |
isobutylparaben) preservative |
2016265981 29 Nov 2016
It had not previously been known to formulate urea with a film forming polymer and, when done, the inventor found that it gave surprisingly good results.
The formulation is preferably prepared according to the following procedure a) obtain 603 gm of water at room temperature;
b) slowly add 300 gm of urea to the water, with constant stirring, until completely dissolved;
c) slowly add 45 gm of Avalure 450 (PPG-17/IPDI/DMPA copolymer)_film forming polymer to the mix, with constant stirring, until a milky white homogeneous solution is achieved;
d) add 50 gm of glycerine to the mix, with constant stirring, until dissolved;
e) add 2 gm of a preservative to the mix (e.g. phenoxyethanol, methyl paraben, ethyl paraben, propyl paraben and butyl paraben), with constant stirring, until dissolved; and
f) continue mixing until a milky-white solution free of particles is achieved.
When created, the formulation is substantially waterproof (i.e. will not readily wash off the skin), is non-staining and does not have the sort of greasy or oily consistency of many prior art formulations.
As indicated in the table, the urea is preferably at an amount of 30% by weight. However, in other embodiments of the invention there may be more, or less. For example, the urea may be at 25-35% by weight.
As well as providing humectant functionality, the glycerine assists in making the formulation smooth. It imparts lubricant type characteristics.
It will be appreciated that alternative film forming polymers, humectants and preservatives may be used in place of those specifically mentioned above. However, in each case the film forming polymer will be sufficient to give a stable urea containing film when applied to a human topically, and at least much of the urea able to be readily
2016265981 29 Nov 2016 absorbed into the skin. Preferably the formulation is a spray-on one and is delivered by way of a spray dispenser.
While some preferred forms of the invention have been described by way of example, 5 it should be understood that modifications and improvements can occur without departing from the scope of the following claims.
2016265981 05 Jul 2018
Claims (8)
1. A method of treating dryness or cracking in human skin comprising applying a formulation to the skin, the formulation having:
5 · about 25% to about 35% urea, by weight;
• film forming polymer;
• humectant;
• preservative; and • water
10 the above ingredients being combined such that the preservative protects the formulation against bacterial invasion, the humectant assists the formulation to retain water, and the water and film forming polymer enable the urea to be applied to human skin such that the urea sits on the skin as a stable film and is gradually absorbed into the skin to alleviate dryness or cracking, the film being substantially
15 waterproof.
2. A method of treating dryness or cracking in human skin according to claim 1, wherein the formulation has about 30% urea, by weight.
3. A method of treating dryness or cracking in human skin according to claim 1, or 2,
20 wherein the formulation has 30% urea, by weight.
4. A method of treating dryness or cracking in human skin according to claim 1, wherein the formulation has 25% to 35% urea by weight.
25
5. A method of treating dryness or cracking in human skin according to any one of claims 1 to 4, wherein the film forming polymer of the formulation comprises a urethane polymer.
6. A method of treating dryness or cracking in human skin according to claim 5,
30 wherein the film forming polymer of the formulation comprises PPG-17/IPDI/DMPA copolymer.
7. A method of treating dryness or cracking in human skin according to any one of claims 1 to 6, wherein the humectant of the formulation comprises glycerine.
8. A method of treating dryness or cracking in human skin according to any one of claims 1 to 7, wherein the preservative of the formulation comprises one or more of phenoxyethanol, methyl paraben, ethyl paraben, propyl paraben and butyl paraben, and preferably a combination of all of these.
2016265981 05 Jul 2018
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2016265981A AU2016265981B2 (en) | 2015-04-01 | 2016-11-29 | Urea based skin treatment |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2015201680 | 2015-04-01 | ||
AU2015201680A AU2015201680B2 (en) | 2015-04-01 | 2015-04-01 | Urea based skin treatment |
AU2016265981A AU2016265981B2 (en) | 2015-04-01 | 2016-11-29 | Urea based skin treatment |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
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AU2015201680A Division AU2015201680B2 (en) | 2015-04-01 | 2015-04-01 | Urea based skin treatment |
Publications (2)
Publication Number | Publication Date |
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AU2016265981A1 AU2016265981A1 (en) | 2016-12-15 |
AU2016265981B2 true AU2016265981B2 (en) | 2018-07-26 |
Family
ID=57127780
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2015201680A Active AU2015201680B2 (en) | 2015-04-01 | 2015-04-01 | Urea based skin treatment |
AU2016265981A Active AU2016265981B2 (en) | 2015-04-01 | 2016-11-29 | Urea based skin treatment |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2015201680A Active AU2015201680B2 (en) | 2015-04-01 | 2015-04-01 | Urea based skin treatment |
Country Status (1)
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AU (2) | AU2015201680B2 (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4690815A (en) * | 1985-08-15 | 1987-09-01 | Charles Of The Ritz Group Ltd. | Method for testing skin for presence of moisturizer |
US20040146555A1 (en) * | 2001-05-30 | 2004-07-29 | Aventis Pharma Deutschland Gmbh | Composition for removing abnormal keratinous material |
US20070258935A1 (en) * | 2006-05-08 | 2007-11-08 | Mcentire Edward Enns | Water dispersible films for delivery of active agents to the epidermis |
-
2015
- 2015-04-01 AU AU2015201680A patent/AU2015201680B2/en active Active
-
2016
- 2016-11-29 AU AU2016265981A patent/AU2016265981B2/en active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4690815A (en) * | 1985-08-15 | 1987-09-01 | Charles Of The Ritz Group Ltd. | Method for testing skin for presence of moisturizer |
US20040146555A1 (en) * | 2001-05-30 | 2004-07-29 | Aventis Pharma Deutschland Gmbh | Composition for removing abnormal keratinous material |
US20070258935A1 (en) * | 2006-05-08 | 2007-11-08 | Mcentire Edward Enns | Water dispersible films for delivery of active agents to the epidermis |
Also Published As
Publication number | Publication date |
---|---|
AU2015201680B2 (en) | 2016-12-22 |
AU2016265981A1 (en) | 2016-12-15 |
AU2015201680A1 (en) | 2016-10-20 |
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