AU2015346350C1 - Anti-thyroglobulin t cell receptors - Google Patents

Anti-thyroglobulin t cell receptors Download PDF

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Publication number
AU2015346350C1
AU2015346350C1 AU2015346350A AU2015346350A AU2015346350C1 AU 2015346350 C1 AU2015346350 C1 AU 2015346350C1 AU 2015346350 A AU2015346350 A AU 2015346350A AU 2015346350 A AU2015346350 A AU 2015346350A AU 2015346350 C1 AU2015346350 C1 AU 2015346350C1
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AU
Australia
Prior art keywords
ser
leu
seq
gly
ala
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AU2015346350A
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English (en)
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AU2015346350A2 (en
AU2015346350A1 (en
AU2015346350B2 (en
Inventor
Kenichi Hanada
Qiong J. Wang
James C. Yang
Zhiya Yu
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United States Department of Health and Human Services
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Government of the United States of America
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Publication of AU2015346350A1 publication Critical patent/AU2015346350A1/en
Publication of AU2015346350A2 publication Critical patent/AU2015346350A2/en
Application granted granted Critical
Publication of AU2015346350B2 publication Critical patent/AU2015346350B2/en
Publication of AU2015346350C1 publication Critical patent/AU2015346350C1/en
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001144—Hormones, e.g. calcitonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5156—Animal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2318/00—Antibody mimetics or scaffolds
    • C07K2318/20—Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2015346350A 2014-11-14 2015-11-12 Anti-thyroglobulin t cell receptors Active AU2015346350C1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462079713P 2014-11-14 2014-11-14
US62/079,713 2014-11-14
PCT/US2015/060282 WO2016077525A2 (en) 2014-11-14 2015-11-12 Anti-human thyroglobulin t cell receptors

Publications (4)

Publication Number Publication Date
AU2015346350A1 AU2015346350A1 (en) 2017-05-25
AU2015346350A2 AU2015346350A2 (en) 2017-06-22
AU2015346350B2 AU2015346350B2 (en) 2021-06-24
AU2015346350C1 true AU2015346350C1 (en) 2022-01-06

Family

ID=54704113

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2015346350A Active AU2015346350C1 (en) 2014-11-14 2015-11-12 Anti-thyroglobulin t cell receptors

Country Status (6)

Country Link
US (3) US10450372B2 (cg-RX-API-DMAC10.html)
EP (2) EP3218404B1 (cg-RX-API-DMAC10.html)
JP (1) JP6666342B2 (cg-RX-API-DMAC10.html)
AU (1) AU2015346350C1 (cg-RX-API-DMAC10.html)
CA (1) CA2967778C (cg-RX-API-DMAC10.html)
WO (1) WO2016077525A2 (cg-RX-API-DMAC10.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3218404B1 (en) * 2014-11-14 2021-01-06 The United States of America, as represented by The Secretary, Department of Health and Human Services Human anti-thyroglobulin t cell receptors
CA3070468A1 (en) 2017-09-01 2019-03-07 Dana-Farber Cancer Institute, Inc. Immunogenic peptides specific to bcma and taci antigens for treatment of cancer
EP3941938A1 (en) 2019-03-06 2022-01-26 Dana-Farber Cancer Institute, Inc. T cell receptors specific to b-cell maturation antigen for treatment of cancer
EP4519303A1 (en) * 2022-05-04 2025-03-12 Deutsches Krebsforschungszentrum T cell receptor derived binding polypeptides
WO2024097652A2 (en) * 2022-10-31 2024-05-10 Legend Biotech Ireland Limited Anti-kras t cell receptors and engineered cells

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874845A (en) * 1984-06-13 1989-10-17 Massachusetts Institute Of Technology T lymphocyte receptor subunit

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8034334B2 (en) 2002-09-06 2011-10-11 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Immunotherapy with in vitro-selected antigen-specific lymphocytes after non-myeloablative lymphodepleting chemotherapy
US8383099B2 (en) 2009-08-28 2013-02-26 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Adoptive cell therapy with young T cells
US20120244133A1 (en) 2011-03-22 2012-09-27 The United States of America, as represented by the Secretary, Department of Health and Methods of growing tumor infiltrating lymphocytes in gas-permeable containers
AU2012262520A1 (en) 2011-05-27 2014-01-23 Cytocure Llc Methods, compositions, and kits for the treatment of cancer
CN106459165B (zh) * 2014-04-01 2021-04-20 拜恩科技细胞&基因治疗有限公司 密封蛋白-6特异性免疫受体和t细胞表位
EP3218404B1 (en) * 2014-11-14 2021-01-06 The United States of America, as represented by The Secretary, Department of Health and Human Services Human anti-thyroglobulin t cell receptors

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874845A (en) * 1984-06-13 1989-10-17 Massachusetts Institute Of Technology T lymphocyte receptor subunit

Also Published As

Publication number Publication date
JP2017536821A (ja) 2017-12-14
CA2967778C (en) 2024-04-16
US20220389093A1 (en) 2022-12-08
EP3808770B1 (en) 2025-10-29
US12275786B2 (en) 2025-04-15
EP3218404A2 (en) 2017-09-20
WO2016077525A3 (en) 2016-12-29
US10450372B2 (en) 2019-10-22
WO2016077525A2 (en) 2016-05-19
AU2015346350A2 (en) 2017-06-22
EP3808770A1 (en) 2021-04-21
AU2015346350A1 (en) 2017-05-25
US20180244768A1 (en) 2018-08-30
EP3218404B1 (en) 2021-01-06
US20200102383A1 (en) 2020-04-02
JP6666342B2 (ja) 2020-03-13
AU2015346350B2 (en) 2021-06-24
CA2967778A1 (en) 2016-05-19
US11440956B2 (en) 2022-09-13

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Legal Events

Date Code Title Description
DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE INVENTION TITLE TO READ ANTI-THYROGLOBULIN T CELL RECEPTORS

DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 15 MAY 2017

DA2 Applications for amendment section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 14 SEP 2021

DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT FILED 14 SEP 2021

FGA Letters patent sealed or granted (standard patent)