AU2015336008B2 - Promoting epithelial regeneration post tonsillectomy using heparin binding epidermal growth factor like growth factor - Google Patents
Promoting epithelial regeneration post tonsillectomy using heparin binding epidermal growth factor like growth factor Download PDFInfo
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- AU2015336008B2 AU2015336008B2 AU2015336008A AU2015336008A AU2015336008B2 AU 2015336008 B2 AU2015336008 B2 AU 2015336008B2 AU 2015336008 A AU2015336008 A AU 2015336008A AU 2015336008 A AU2015336008 A AU 2015336008A AU 2015336008 B2 AU2015336008 B2 AU 2015336008B2
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1808—Epidermal growth factor [EGF] urogastrone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Biophysics (AREA)
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- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
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|---|---|---|---|
| AU2019272030A AU2019272030A1 (en) | 2014-10-21 | 2019-11-29 | Promoting epithelial regeneration post tonsillectomy using heparin binding epidermal growth factor like growth factor |
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| US201462066564P | 2014-10-21 | 2014-10-21 | |
| US62/066,564 | 2014-10-21 | ||
| PCT/US2015/056651 WO2016064998A1 (en) | 2014-10-21 | 2015-10-21 | Promoting epithelial regeneration post tonsillectomy using heparin binding epidermal growth factor like growth factor |
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| AU2019272030A Division AU2019272030A1 (en) | 2014-10-21 | 2019-11-29 | Promoting epithelial regeneration post tonsillectomy using heparin binding epidermal growth factor like growth factor |
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| AU2019272030A Abandoned AU2019272030A1 (en) | 2014-10-21 | 2019-11-29 | Promoting epithelial regeneration post tonsillectomy using heparin binding epidermal growth factor like growth factor |
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| CA (1) | CA2964378A1 (enExample) |
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| US20210138036A1 (en) * | 2014-10-21 | 2021-05-13 | The Board Of Trustees Of The Leland Stanford Junior University | Method for Treating or Preventing Radiotherapy-and Chemotherapy-Associated Oral Mucositis Using Locally Administered Heparin Binding Epidermal Growth Factor Like Growth Factor (HB-EGF) |
| WO2019231860A1 (en) * | 2018-05-27 | 2019-12-05 | The Board Of Trustees Of The Leland Stanford Junior University | Method for treating or preventing radiotherapy- and chemotherapy-associated oral mucositis using locally administered heparin binding epidermal growth factor like growth factor (hb-egf) |
| EP3820460A1 (en) * | 2018-07-12 | 2021-05-19 | The Board of Trustees of the Leland Stanford Junior University | Methods for reversing hiv latency using baf complex modulating compounds |
| JP7475611B2 (ja) * | 2019-05-31 | 2024-04-30 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 粘膜付着性ミクロゲル組成物およびそれを使用するための方法 |
| US20240050593A1 (en) * | 2020-12-18 | 2024-02-15 | Duke University | Compositions For and Methods of Enhancing Spinal Cord Tissue Regeneration |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5811393A (en) * | 1990-10-16 | 1998-09-22 | The Childrens Medical Center Corp. | Heparin binding mitogen with homology to epidermal growth factor (EGF) |
| WO2007061411A2 (en) * | 2005-11-21 | 2007-05-31 | Kevin Todd Kotecki | A method for developing and marketing a post operative home recovery kit for use by a patient after discharge from a hospital and for recuperation at home |
| WO2008008389A2 (en) * | 2006-07-10 | 2008-01-17 | Sinexus, Inc. | Implantable sustained drug delivery device for releasing active agents to the osteomeatal complex |
| US20130165376A1 (en) * | 2007-04-30 | 2013-06-27 | Nationwide Children's Hospital Inc. | Heparin Binding Epidermal Growth Factor (HB-EGF) for Use in Methods of Treating and Preventing Intestinal Injury Related to Hemorrhagic Shock and Resuscitation |
| US20140154236A1 (en) * | 2009-04-27 | 2014-06-05 | Intersect Ent, Inc. | Devices and methods for treating pain associated with tonsillectomies |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5112620A (en) * | 1990-09-20 | 1992-05-12 | Mikkur, Inc. | Polyethylene glycol ointment for apthous ulcers |
| US6682501B1 (en) * | 1996-02-23 | 2004-01-27 | Gyrus Ent, L.L.C. | Submucosal tonsillectomy apparatus and method |
| US8912165B2 (en) * | 1999-03-12 | 2014-12-16 | Biotec Pharmacon Asa | Methods of skin treatment and use of water-soluble β-(1,3) glucans as active agents for producing therapeutic skin treatment agents |
| WO2007014167A2 (en) * | 2005-07-22 | 2007-02-01 | Five Prime Therapeutics, Inc. | Compositions for and methods of treating epithelial diseases with growth factors |
| US10058631B2 (en) * | 2014-07-09 | 2018-08-28 | Cook Medical Technologies Llc | Tonsillectomy sponge |
| EP3573697A4 (en) * | 2017-01-27 | 2020-11-11 | The UAB Research Foundation | PROLONGED INTRA-TONSILLARY DRUG ADMINISTRATION WITH NEEDLE NETWORK |
-
2015
- 2015-10-21 EP EP15853304.2A patent/EP3209322A4/en not_active Withdrawn
- 2015-10-21 JP JP2017521530A patent/JP2017537067A/ja active Pending
- 2015-10-21 AU AU2015336008A patent/AU2015336008B2/en not_active Ceased
- 2015-10-21 CA CA2964378A patent/CA2964378A1/en not_active Abandoned
- 2015-10-21 WO PCT/US2015/056651 patent/WO2016064998A1/en not_active Ceased
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2017
- 2017-04-20 US US15/492,773 patent/US20170232065A1/en not_active Abandoned
-
2019
- 2019-11-29 AU AU2019272030A patent/AU2019272030A1/en not_active Abandoned
-
2020
- 2020-08-19 US US16/997,607 patent/US20210038690A1/en not_active Abandoned
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5811393A (en) * | 1990-10-16 | 1998-09-22 | The Childrens Medical Center Corp. | Heparin binding mitogen with homology to epidermal growth factor (EGF) |
| WO2007061411A2 (en) * | 2005-11-21 | 2007-05-31 | Kevin Todd Kotecki | A method for developing and marketing a post operative home recovery kit for use by a patient after discharge from a hospital and for recuperation at home |
| WO2008008389A2 (en) * | 2006-07-10 | 2008-01-17 | Sinexus, Inc. | Implantable sustained drug delivery device for releasing active agents to the osteomeatal complex |
| US20130165376A1 (en) * | 2007-04-30 | 2013-06-27 | Nationwide Children's Hospital Inc. | Heparin Binding Epidermal Growth Factor (HB-EGF) for Use in Methods of Treating and Preventing Intestinal Injury Related to Hemorrhagic Shock and Resuscitation |
| US20140154236A1 (en) * | 2009-04-27 | 2014-06-05 | Intersect Ent, Inc. | Devices and methods for treating pain associated with tonsillectomies |
Non-Patent Citations (2)
| Title |
|---|
| JM KIM ET AL, "Effects of HB-EGF and epiregulin on wound healing of gingival cells in vitro: Roles of HB-EGF and epiregulin in wound healing", ORAL DISEASES, GB, (2011-07-19), vol. 17, no. 8, pages 785 - 793 * |
| VAIMAN et al., "Oxycodone and Dexamethasone for pain management after tonsillectomy: A placebo-controlled EMG assessed clinical trial.", Med Sci Monit, (2011-10-01) * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2015336008A1 (en) | 2017-05-25 |
| JP2017537067A (ja) | 2017-12-14 |
| CA2964378A1 (en) | 2016-04-28 |
| AU2019272030A1 (en) | 2019-12-19 |
| EP3209322A1 (en) | 2017-08-30 |
| US20210038690A1 (en) | 2021-02-11 |
| EP3209322A4 (en) | 2018-07-18 |
| US20170232065A1 (en) | 2017-08-17 |
| WO2016064998A1 (en) | 2016-04-28 |
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