AU2014364800A1 - Extruded extended release abuse deterrent pill - Google Patents

Extruded extended release abuse deterrent pill Download PDF

Info

Publication number
AU2014364800A1
AU2014364800A1 AU2014364800A AU2014364800A AU2014364800A1 AU 2014364800 A1 AU2014364800 A1 AU 2014364800A1 AU 2014364800 A AU2014364800 A AU 2014364800A AU 2014364800 A AU2014364800 A AU 2014364800A AU 2014364800 A1 AU2014364800 A1 AU 2014364800A1
Authority
AU
Australia
Prior art keywords
extended release
formulation
oral
abuse deterrent
abuse
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2014364800A
Other languages
English (en)
Inventor
Steven F. Kemeny
Nicholas R. Myslinski
Edwin R. Thompson
Eric R. Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PHARMACEUTICAL MANUFACTURING RESEARCH SERVICES Inc
Original Assignee
Pharmaceutical Manufacturing Research Services Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/457,714 external-priority patent/US10195153B2/en
Application filed by Pharmaceutical Manufacturing Research Services Inc filed Critical Pharmaceutical Manufacturing Research Services Inc
Publication of AU2014364800A1 publication Critical patent/AU2014364800A1/en
Priority to AU2018253567A priority Critical patent/AU2018253567B2/en
Priority to AU2019216710A priority patent/AU2019216710A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Addiction (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2014364800A 2013-12-17 2014-12-17 Extruded extended release abuse deterrent pill Abandoned AU2014364800A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2018253567A AU2018253567B2 (en) 2013-12-17 2018-10-25 Extruded extended release abuse deterrent pill
AU2019216710A AU2019216710A1 (en) 2013-12-17 2019-08-16 Extruded extended release abuse deterrent pill

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201361917074P 2013-12-17 2013-12-17
US201361917120P 2013-12-17 2013-12-17
US61/917,074 2013-12-17
US61/917,120 2013-12-17
US201461980254P 2014-04-16 2014-04-16
US201461980259P 2014-04-16 2014-04-16
US61/980,254 2014-04-16
US61/980,259 2014-04-16
US14/457,714 2014-08-12
US14/457,714 US10195153B2 (en) 2013-08-12 2014-08-12 Extruded immediate release abuse deterrent pill
PCT/US2014/070942 WO2015095387A1 (en) 2013-12-17 2014-12-17 Extruded extended release abuse deterrent pill

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2018253567A Division AU2018253567B2 (en) 2013-12-17 2018-10-25 Extruded extended release abuse deterrent pill

Publications (1)

Publication Number Publication Date
AU2014364800A1 true AU2014364800A1 (en) 2016-07-07

Family

ID=53403652

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2014364800A Abandoned AU2014364800A1 (en) 2013-12-17 2014-12-17 Extruded extended release abuse deterrent pill
AU2018253567A Ceased AU2018253567B2 (en) 2013-12-17 2018-10-25 Extruded extended release abuse deterrent pill
AU2019216710A Abandoned AU2019216710A1 (en) 2013-12-17 2019-08-16 Extruded extended release abuse deterrent pill

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2018253567A Ceased AU2018253567B2 (en) 2013-12-17 2018-10-25 Extruded extended release abuse deterrent pill
AU2019216710A Abandoned AU2019216710A1 (en) 2013-12-17 2019-08-16 Extruded extended release abuse deterrent pill

Country Status (5)

Country Link
EP (1) EP3082775A4 (de)
JP (2) JP6403780B2 (de)
AU (3) AU2014364800A1 (de)
CA (1) CA2934078C (de)
WO (1) WO2015095387A1 (de)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE427124T1 (de) * 1996-06-26 2009-04-15 Univ Texas Heiss-geschmolzene extrudierbare pharmazeutische formulierung
PL1765303T5 (pl) * 2004-07-01 2023-05-22 Grünenthal GmbH Tabletka doustna zabezpieczona przed nadużywaniem
US20080152595A1 (en) * 2004-11-24 2008-06-26 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse of orally administered pharmaceutical products
DE102007011485A1 (de) * 2007-03-07 2008-09-11 Grünenthal GmbH Darreichungsform mit erschwertem Missbrauch
GB0909680D0 (en) * 2009-06-05 2009-07-22 Euro Celtique Sa Dosage form
AR087360A1 (es) * 2011-07-29 2014-03-19 Gruenenthal Gmbh Tableta a prueba de manipulacion que proporciona liberacion de farmaco inmediato
WO2013158810A1 (en) * 2012-04-18 2013-10-24 Mallinckrodt Llc Immediate release pharmaceutical compositions with abuse deterrent properties
JP2015521988A (ja) * 2012-07-06 2015-08-03 イガレット・リミテッド 制御放出用乱用防止性医薬組成物
US10195153B2 (en) * 2013-08-12 2019-02-05 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill

Also Published As

Publication number Publication date
CA2934078C (en) 2019-08-06
WO2015095387A1 (en) 2015-06-25
EP3082775A1 (de) 2016-10-26
AU2019216710A1 (en) 2019-09-12
AU2018253567B2 (en) 2019-05-23
EP3082775A4 (de) 2017-05-17
CA2934078A1 (en) 2015-06-25
JP6403780B2 (ja) 2018-10-10
JP6678212B2 (ja) 2020-04-08
JP2019001816A (ja) 2019-01-10
JP2017503780A (ja) 2017-02-02
AU2018253567A1 (en) 2018-11-08

Similar Documents

Publication Publication Date Title
US10639281B2 (en) Extruded immediate release abuse deterrent pill
US10792254B2 (en) Extruded extended release abuse deterrent pill
WO2014191397A1 (en) Tamper-resistant dosage form containing one or more particles
EP3285745A1 (de) Manipulationssichere darreichungsform mit sofortiger freisetzung und widerstand gegen lösungsmittelextraktion
US20160199369A1 (en) Extruded Immediate Release Abuse Deterrent Pill
AU2018253567B2 (en) Extruded extended release abuse deterrent pill
EP3032948B1 (de) Extrudierte missbrauchssichere pille mit sofortiger freisetzung
US10172797B2 (en) Extruded extended release abuse deterrent pill
EP3169315B1 (de) Missbrauchssichere flüssigkeitsfülldosierform mit unmittelbarer freisetzung
CA3078272A1 (en) Modified release abuse deterrent dosage forms

Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted