AU2014278231B2 - Urea derivatives and uses thereof - Google Patents
Urea derivatives and uses thereof Download PDFInfo
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- AU2014278231B2 AU2014278231B2 AU2014278231A AU2014278231A AU2014278231B2 AU 2014278231 B2 AU2014278231 B2 AU 2014278231B2 AU 2014278231 A AU2014278231 A AU 2014278231A AU 2014278231 A AU2014278231 A AU 2014278231A AU 2014278231 B2 AU2014278231 B2 AU 2014278231B2
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- certain embodiments
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- instance
- unsubstituted
- alkyl
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- 150000001875 compounds Chemical class 0.000 claims abstract description 205
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- 125000000217 alkyl group Chemical group 0.000 claims description 318
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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| CA2914815A1 (en) | 2013-06-11 | 2014-12-18 | Kala Pharmaceuticals, Inc. | Urea derivatives and uses thereof |
| EP3230272B1 (en) | 2014-12-10 | 2020-08-19 | Kala Pharmaceuticals, Inc. | 1-amino-triazolo(1,5-a)pyridine-substituted urea derivative and uses thereof |
| SG11201804210XA (en) * | 2015-11-20 | 2018-06-28 | Mingsight Pharmaceuticals Inc | Treatment of autoimmune disease |
| WO2018090974A1 (zh) * | 2016-11-17 | 2018-05-24 | 思路迪（北京）医药科技有限公司 | 一种具有抗癌作用的化合物及其制备方法和应用 |
| CN114269339A (zh) | 2019-12-16 | 2022-04-01 | 苏州锐明新药研发有限公司 | 一种萘脲类化合物的应用 |
| CN115348957B (zh) * | 2019-12-31 | 2025-11-25 | 诺华制药股份有限公司 | 用于治疗与sting活性有关的疾病的化合物和组合物 |
| FI4146348T3 (fi) | 2020-05-08 | 2024-09-25 | Halia Therapeutics Inc | Nek7-kinaasin estäjiä |
| CN115487183B (zh) * | 2021-06-18 | 2024-07-26 | 苏州锐明新药研发有限公司 | 萘脲类化合物在制备治疗翼状胬肉的药物中的应用 |
| EP4635495A1 (en) * | 2022-12-13 | 2025-10-22 | Suzhou Raymon Pharmaceuticals Company, Ltd. | Use of naphthylurea compounds in preparation of drugs for treating pterygium |
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| WO2012003141A1 (en) * | 2010-07-02 | 2012-01-05 | Alcon Research, Ltd. | Compounds for the treatment of posterior segment disorders and diseases |
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2014
- 2014-06-11 CA CA2914815A patent/CA2914815A1/en not_active Abandoned
- 2014-06-11 US US14/301,653 patent/US9212145B2/en active Active
- 2014-06-11 WO PCT/US2014/041930 patent/WO2014201127A2/en not_active Ceased
- 2014-06-11 EP EP14811423.4A patent/EP3030239A4/en not_active Withdrawn
- 2014-06-11 JP JP2016519614A patent/JP6469661B2/ja not_active Expired - Fee Related
- 2014-06-11 AU AU2014278231A patent/AU2014278231B2/en not_active Ceased
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2015
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2017
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- 2017-10-12 US US15/782,696 patent/US10059692B2/en active Active
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2018
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2019
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2020
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2022
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2012003141A1 (en) * | 2010-07-02 | 2012-01-05 | Alcon Research, Ltd. | Compounds for the treatment of posterior segment disorders and diseases |
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Owner name: KALA BIO, INC. Free format text: FORMER NAME(S): KALA PHARMACEUTICALS, INC. |
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