AU2014273089B2 - A LAGLIDADG homing endonuclease cleaving the C-C Chemokine Receptor Type-5 (CCR5) gene and uses thereof - Google Patents

A LAGLIDADG homing endonuclease cleaving the C-C Chemokine Receptor Type-5 (CCR5) gene and uses thereof Download PDF

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AU2014273089B2
AU2014273089B2 AU2014273089A AU2014273089A AU2014273089B2 AU 2014273089 B2 AU2014273089 B2 AU 2014273089B2 AU 2014273089 A AU2014273089 A AU 2014273089A AU 2014273089 A AU2014273089 A AU 2014273089A AU 2014273089 B2 AU2014273089 B2 AU 2014273089B2
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Alexander ASTRAKHAN
Jordan JARJOUR
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Cellectis SA
Precision Genome Engineering Inc
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    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90Stable introduction of foreign DNA into chromosome
    • C12N15/902Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/907Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
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    • A61K38/46Hydrolases (3)
    • A61K38/465Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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AU2014273089A 2013-05-31 2014-05-28 A LAGLIDADG homing endonuclease cleaving the C-C Chemokine Receptor Type-5 (CCR5) gene and uses thereof Active AU2014273089B2 (en)

Applications Claiming Priority (3)

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DKPA201370302 2013-05-31
DKPA201370302 2013-05-31
PCT/EP2014/061186 WO2014191525A1 (en) 2013-05-31 2014-05-28 A laglidadg homing endonuclease cleaving the c-c chemokine receptor type-5 (ccr5) gene and uses thereof

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AU2014273089A1 AU2014273089A1 (en) 2015-12-24
AU2014273089B2 true AU2014273089B2 (en) 2018-02-22

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US (1) US10006052B2 (https=)
EP (1) EP3004149B1 (https=)
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CA2913871A1 (en) 2014-12-04
WO2014191525A1 (en) 2014-12-04
CA2913871C (en) 2021-07-13
AU2014273089A1 (en) 2015-12-24
US20160102323A1 (en) 2016-04-14
HK1223373A1 (en) 2017-07-28
EP3004149A1 (en) 2016-04-13
US10006052B2 (en) 2018-06-26
JP6488283B2 (ja) 2019-03-20
JP2016520319A (ja) 2016-07-14
EP3004149B1 (en) 2018-12-19

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