AU2012358983B2 - Compounds acting at multiple prostaglandin receptors giving a general anti-inflammatory response - Google Patents

Compounds acting at multiple prostaglandin receptors giving a general anti-inflammatory response Download PDF

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Publication number
AU2012358983B2
AU2012358983B2 AU2012358983A AU2012358983A AU2012358983B2 AU 2012358983 B2 AU2012358983 B2 AU 2012358983B2 AU 2012358983 A AU2012358983 A AU 2012358983A AU 2012358983 A AU2012358983 A AU 2012358983A AU 2012358983 B2 AU2012358983 B2 AU 2012358983B2
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disorders
diseases
group
alkyl
disease
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AU2012358983A1 (en
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William R. Carling
Jussi J. Kangasmetsa
Jose L. Martos
Jenny W. Wang
David F. Woodward
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Allergan Inc
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Allergan Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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    • A61P25/20—Hypnotics; Sedatives
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
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    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • A61P37/02—Immunomodulators
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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    • A61P9/08—Vasodilators for multiple indications
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  • Organic Chemistry (AREA)
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  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
AU2012358983A 2011-12-21 2012-12-19 Compounds acting at multiple prostaglandin receptors giving a general anti-inflammatory response Ceased AU2012358983B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161578456P 2011-12-21 2011-12-21
US61/578,456 2011-12-21
PCT/US2012/070710 WO2013096501A1 (en) 2011-12-21 2012-12-19 Compounds acting at multiple prostaglandin receptors giving a general anti-inflammatory response

Publications (2)

Publication Number Publication Date
AU2012358983A1 AU2012358983A1 (en) 2014-07-17
AU2012358983B2 true AU2012358983B2 (en) 2017-09-14

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AU2012358983A Ceased AU2012358983B2 (en) 2011-12-21 2012-12-19 Compounds acting at multiple prostaglandin receptors giving a general anti-inflammatory response

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US (1) US8969589B2 (https=)
EP (1) EP2794574B1 (https=)
JP (1) JP6132851B2 (https=)
AU (1) AU2012358983B2 (https=)
CA (1) CA2860392C (https=)
WO (1) WO2013096501A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106146400A (zh) * 2015-03-20 2016-11-23 四川大学 苄基-1h-吡唑、苄基-1h-吡咯衍生物及其制备方法和用途
US9827225B2 (en) 2016-01-25 2017-11-28 Jenivision Inc. Use of prostacyclin antagonists for treating ocular surface nociception
WO2017153234A1 (de) * 2016-03-09 2017-09-14 Bayer Pharma Aktiengesellschaft Substituierte n-cyclo-2-arylchinolin-4-carboxamide und ihre verwendung
WO2017153231A1 (de) * 2016-03-09 2017-09-14 Bayer Pharma Aktiengesellschaft Substituierte n-cyclo-2-arylisochinolinon-4-carboxamide und ihre verwendung
US20230390303A1 (en) 2020-11-13 2023-12-07 Ono Pharmaceutical Co., Ltd. Cancer treatment by combination of ep4 antagonist and immune checkpoint inhibitor
CN118184646A (zh) * 2024-05-14 2024-06-14 苏州弘道新材料有限公司 用于光伏胶膜的吡唑啉衍生物光转换材料及其制备方法和应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070060596A1 (en) * 2003-10-24 2007-03-15 Giblin Gerard M P Heterocyclyl compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166452A (en) 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
US7273883B2 (en) 2000-09-14 2007-09-25 Allergan, Inc. Prostaglandin EP4 antagonist
US7217725B2 (en) 2000-09-14 2007-05-15 Allergan, Inc. Prostaglandin D2 antagonist
US6511999B2 (en) 2000-09-14 2003-01-28 Allergan, Inc. Interheteroaryl 7-oxabicyclic [2.2.1]heptane oxazoles as prostaglandin F2α antagonists
GB0508472D0 (en) 2005-04-26 2005-06-01 Glaxo Group Ltd Compounds
US8492424B2 (en) * 2010-07-01 2013-07-23 Allergan, Inc. Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070060596A1 (en) * 2003-10-24 2007-03-15 Giblin Gerard M P Heterocyclyl compounds

Also Published As

Publication number Publication date
JP6132851B2 (ja) 2017-05-24
EP2794574A1 (en) 2014-10-29
US8969589B2 (en) 2015-03-03
EP2794574B1 (en) 2017-11-08
US20130165665A1 (en) 2013-06-27
AU2012358983A1 (en) 2014-07-17
JP2015500883A (ja) 2015-01-08
CA2860392C (en) 2016-08-30
CA2860392A1 (en) 2013-06-27
WO2013096501A1 (en) 2013-06-27

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