AU2012343536B2 - Immunogenic treatment of cancer - Google Patents
Immunogenic treatment of cancer Download PDFInfo
- Publication number
- AU2012343536B2 AU2012343536B2 AU2012343536A AU2012343536A AU2012343536B2 AU 2012343536 B2 AU2012343536 B2 AU 2012343536B2 AU 2012343536 A AU2012343536 A AU 2012343536A AU 2012343536 A AU2012343536 A AU 2012343536A AU 2012343536 B2 AU2012343536 B2 AU 2012343536B2
- Authority
- AU
- Australia
- Prior art keywords
- cancer
- tumour
- immunomodulator
- therapy
- cell death
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Radiation-Therapy Devices (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1120779.2A GB201120779D0 (en) | 2011-12-02 | 2011-12-02 | Cancer therapy |
| GB1120779.2 | 2011-12-02 | ||
| PCT/GB2012/052992 WO2013079980A1 (en) | 2011-12-02 | 2012-12-03 | Immunogenic treatment of cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2012343536A1 AU2012343536A1 (en) | 2014-06-05 |
| AU2012343536B2 true AU2012343536B2 (en) | 2017-08-24 |
Family
ID=45509083
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2012343536A Active AU2012343536B2 (en) | 2011-12-02 | 2012-12-03 | Immunogenic treatment of cancer |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US20140356397A1 (https=) |
| EP (1) | EP2785361B1 (https=) |
| JP (1) | JP6085611B2 (https=) |
| KR (1) | KR20140097419A (https=) |
| CN (1) | CN104023733A (https=) |
| AU (1) | AU2012343536B2 (https=) |
| BR (1) | BR112014012880A2 (https=) |
| CA (1) | CA2857429A1 (https=) |
| GB (1) | GB201120779D0 (https=) |
| IL (1) | IL232890A0 (https=) |
| IN (1) | IN2014MN00955A (https=) |
| MX (1) | MX2014006511A (https=) |
| RU (1) | RU2014121335A (https=) |
| SG (1) | SG11201402396XA (https=) |
| WO (1) | WO2013079980A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11963716B2 (en) | 2010-07-19 | 2024-04-23 | Emblation Limited | Apparatus and method for the treatment of dermatological diseases or conditions |
| GB201120779D0 (en) * | 2011-12-02 | 2012-01-11 | Immodulon Therapeutics Ltd | Cancer therapy |
| GB201308325D0 (en) * | 2013-05-09 | 2013-06-19 | Immodulon Therapeutics Ltd | Cancer Therapy |
| WO2015085162A1 (en) | 2013-12-05 | 2015-06-11 | Rfemb Holdings, Llc | Cancer immunotherapy by radiofrequency electrical membrane breakdown (rf-emb) |
| EP3043863B1 (en) | 2013-09-11 | 2019-12-04 | The Board of Trustees of the Leland Stanford Junior University | Arrays of accelerating structures and rapid imaging for facilitating rapid radiation therapies |
| GB201322725D0 (en) * | 2013-12-20 | 2014-02-05 | Immodulon Therapeutics Ltd | Cancer therapy |
| US11141216B2 (en) | 2015-01-30 | 2021-10-12 | Immunsys, Inc. | Radio-frequency electrical membrane breakdown for the treatment of high risk and recurrent prostate cancer, unresectable pancreatic cancer, tumors of the breast, melanoma or other skin malignancies, sarcoma, soft tissue tumors, ductal carcinoma, neoplasia, and intra and extra luminal abnormal tissue |
| RU2733033C2 (ru) * | 2015-06-24 | 2020-09-28 | Иммодьюлон Терапьютикс Лимитед | Ингибитор контрольных точек и целые клетки микобактерий для применения в терапии рака |
| RU2596505C1 (ru) * | 2015-07-02 | 2016-09-10 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский радиологический центр" Министерства здравоохранения Российской Федерации (ФГБУ "НМИРЦ" Минздрава России) | Способ лечения онкологических больных цитотоксическими лимфоцитами |
| US10478194B2 (en) | 2015-09-23 | 2019-11-19 | Covidien Lp | Occlusive devices |
| KR20180108655A (ko) | 2016-01-15 | 2018-10-04 | 알에프이엠비 홀딩스, 엘엘씨 | 암의 면역학적 치료 |
| RU2018136347A (ru) * | 2016-04-14 | 2020-05-14 | Фелдрайх Каро Руиз Аб | Аппарат для радиационной терапии, включающий модуль ионизации и источник ультрафиолетового света |
| CA3058380A1 (en) | 2017-03-28 | 2018-10-04 | Emblation Limited | Stenosis treatment |
| EP3654976A1 (en) | 2017-07-21 | 2020-05-27 | Varian Medical Systems, Inc. | Methods of use of ultra-high dose rate radiation and therapeutic agents |
| RU2664597C1 (ru) * | 2017-12-12 | 2018-08-21 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр радиологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ радиологии" Минздрава России) | Способ комбинированного лечения больных первично операбельным и местно-распространенным неоперабельным раком молочной железы |
| US20220088231A1 (en) | 2018-12-03 | 2022-03-24 | Fusion Pharmaceuticals Inc. | Radioimmunoconjugates and dna damage and repair inhibitor combination therapy |
| EP3918069A1 (en) * | 2019-01-31 | 2021-12-08 | Bar Ilan University | Neoantigens created by aberrant-induced splicing and uses thereof in enhancing immunotherapy |
| EP4082577A4 (en) * | 2019-12-27 | 2024-01-03 | Zeria Pharmaceutical Co., Ltd. | CANCER TREATMENT METHOD AND DRUG |
| EP4376945A1 (en) * | 2021-07-27 | 2024-06-05 | Immodulon Therapeutics Limited | A mycobacterium for use in cancer therapy |
| CN114367060A (zh) * | 2022-01-13 | 2022-04-19 | 深圳大学 | 激光交变电场联合治疗仪 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5207223A (en) | 1990-10-19 | 1993-05-04 | Accuray, Inc. | Apparatus for and method of performing stereotaxic surgery |
| ATE154759T1 (de) * | 1990-11-08 | 1997-07-15 | Univ London | Mycobacterium als adjuvans für antigene |
| US5458125A (en) | 1994-01-28 | 1995-10-17 | Board Of Directors Of The Leland Standford Jr. University | Treatment planning method and apparatus for radiosurgery and radiation therapy |
| CA2369542C (en) | 1999-04-23 | 2009-10-27 | Qlt Inc. | Immuno-adjuvant pdt treatment of metastatic tumors |
| US20020022032A1 (en) | 1999-04-23 | 2002-02-21 | Curry Patrick Mark | Immuno-adjuvant PDT treatment of metastatic tumors |
| WO2003049751A1 (en) * | 2001-12-10 | 2003-06-19 | Bakulesh Mafatlal Khamar | The process of manufacturing a pharmaceutical composition useful for management of cancer |
| AU2003281200A1 (en) | 2002-07-03 | 2004-01-23 | Tasuku Honjo | Immunopotentiating compositions |
| CA2492160A1 (en) | 2002-07-12 | 2004-01-22 | The Johns Hopkins University | Mesothelin vaccines and model systems |
| EP1937303A4 (en) | 2005-10-21 | 2009-11-18 | Med College Georgia Res Inst | INTRODUCTION OF AN INDOLEAMINE-2,3-DIOXYGENASE IN DENDRITIC CELLS BY TLR LIGANDS AND APPLICATIONS THEREOF |
| US20080318252A1 (en) | 2007-04-23 | 2008-12-25 | Scott Kachlany | Rapid assay to test anti-cancer drugs under physiological conditions |
| GB0526033D0 (en) * | 2005-12-21 | 2006-02-01 | Bioeos Ltd | Method |
| EP2010216A4 (en) * | 2006-03-24 | 2010-06-09 | Donald L Morton | MYCOBACTERIAL IMMUNOTHERAPY FOR CANCER TREATMENT |
| WO2008110491A2 (en) | 2007-03-09 | 2008-09-18 | University Of Basel | Chemotherapy of neoplastic diseases using combinations of rapamycin and compounds modulating mtor pathway alone or in combination with heat |
| BR122017025062B8 (pt) | 2007-06-18 | 2021-07-27 | Merck Sharp & Dohme | anticorpo monoclonal ou fragmento de anticorpo para o receptor de morte programada humano pd-1, polinucleotídeo e composição compreendendo o referido anticorpo ou fragmento |
| RS53782B1 (sr) * | 2008-10-01 | 2015-06-30 | Immatics Biotechnologies Gmbh | Preparati tumor-asociranih peptida i odgovarajuća antikancerska vakcina za tretman glioblastoma (gbm) i drugih kancera |
| US8367075B2 (en) | 2010-07-02 | 2013-02-05 | Indian Institute Of Science | Synergistic combination and method thereof |
| EP2683386B1 (en) * | 2011-03-09 | 2017-07-05 | The Johns Hopkins University | Compounds and methods of use in ablative radiotherapy |
| WO2012177624A2 (en) | 2011-06-21 | 2012-12-27 | The Johns Hopkins University | Focused radiation for augmenting immune-based therapies against neoplasms |
| GB201120779D0 (en) * | 2011-12-02 | 2012-01-11 | Immodulon Therapeutics Ltd | Cancer therapy |
| EP2620159A1 (en) | 2012-01-24 | 2013-07-31 | Institut Pasteur | Improved cancer treatment by immunotherapy with bcg or antigenically related non-pathogenic mycobacteria |
| CA2848985A1 (en) | 2012-02-01 | 2013-08-08 | Compugen Ltd. | C10rf32 antibodies, and uses thereof for treatment of cancer |
| US8617520B2 (en) | 2012-02-15 | 2013-12-31 | Immodulon Therapeutics Limited | Cancer therapy |
| GB201308325D0 (en) | 2013-05-09 | 2013-06-19 | Immodulon Therapeutics Ltd | Cancer Therapy |
| GB201322725D0 (en) | 2013-12-20 | 2014-02-05 | Immodulon Therapeutics Ltd | Cancer therapy |
| US10835595B2 (en) | 2014-01-06 | 2020-11-17 | The Trustees Of The University Of Pennsylvania | PD1 and PDL1 antibodies and vaccine combinations and use of same for immunotherapy |
| US10975112B2 (en) | 2015-06-16 | 2021-04-13 | Hangzhou Dac Biotech Co., Ltd. | Linkers for conjugation of cell-binding molecules |
| RU2733033C2 (ru) | 2015-06-24 | 2020-09-28 | Иммодьюлон Терапьютикс Лимитед | Ингибитор контрольных точек и целые клетки микобактерий для применения в терапии рака |
| WO2020002905A1 (en) | 2018-06-25 | 2020-01-02 | Immodulon Therapeutics Limited | Cancer therapy |
-
2011
- 2011-12-02 GB GBGB1120779.2A patent/GB201120779D0/en not_active Ceased
-
2012
- 2012-12-03 RU RU2014121335A patent/RU2014121335A/ru unknown
- 2012-12-03 WO PCT/GB2012/052992 patent/WO2013079980A1/en not_active Ceased
- 2012-12-03 JP JP2014543984A patent/JP6085611B2/ja active Active
- 2012-12-03 CA CA2857429A patent/CA2857429A1/en not_active Abandoned
- 2012-12-03 MX MX2014006511A patent/MX2014006511A/es unknown
- 2012-12-03 KR KR1020147016935A patent/KR20140097419A/ko not_active Withdrawn
- 2012-12-03 US US14/361,992 patent/US20140356397A1/en not_active Abandoned
- 2012-12-03 EP EP12799260.0A patent/EP2785361B1/en active Active
- 2012-12-03 IN IN955MUN2014 patent/IN2014MN00955A/en unknown
- 2012-12-03 CN CN201280059421.0A patent/CN104023733A/zh active Pending
- 2012-12-03 BR BR112014012880A patent/BR112014012880A2/pt not_active IP Right Cessation
- 2012-12-03 SG SG11201402396XA patent/SG11201402396XA/en unknown
- 2012-12-03 AU AU2012343536A patent/AU2012343536B2/en active Active
-
2014
- 2014-05-29 IL IL232890A patent/IL232890A0/en unknown
-
2018
- 2018-12-19 US US16/225,028 patent/US11318193B2/en active Active
-
2020
- 2020-06-30 US US16/916,194 patent/US11554166B2/en active Active
-
2023
- 2023-01-13 US US18/154,177 patent/US20230149525A1/en not_active Abandoned
Non-Patent Citations (5)
| Title |
|---|
| HROUDA et al. "Allogeneic whole-tumour cell vaccination in the rat model of prostate cancer", BJU International, 2000, Vol. 86, Pages 742-748. * |
| O’BRIEN et al., British Journal of Cancer, 2000, Vol. 83, No. 7, Pages 853–857. * |
| STEBBING et al. "An intra-patient placebo-controlled phase I trial to evaluate the safety and tolerability of intradermal IMM-101 in melanoma", Annals of Oncology, 2012, Vol. 23, Pages 1314–1319. * |
| SUR PRABIR KUMAR ET AL., JOURNAL OF THE INDIAN MEDICAL ASSOCIATION, INDIAN MEDICAL ASSOCIATION, CALCUTTA, IN, (20030101), vol. 101, no. 2, ISSN 0019-5847, page 118,120. * |
| Yuk et al. "Bacillus Calmette-Guerin cell wall cytoskeleton enhances colon cancer radiosensitivity through autophagy", Autophagy, 2010, Vol. 6, No. 1, Pages 46-60. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2857429A1 (en) | 2013-06-06 |
| WO2013079980A1 (en) | 2013-06-06 |
| GB201120779D0 (en) | 2012-01-11 |
| JP6085611B2 (ja) | 2017-02-22 |
| IN2014MN00955A (https=) | 2015-04-24 |
| AU2012343536A1 (en) | 2014-06-05 |
| IL232890A0 (en) | 2014-07-31 |
| US20190224294A1 (en) | 2019-07-25 |
| NZ624994A (en) | 2016-10-28 |
| SG11201402396XA (en) | 2014-10-30 |
| EP2785361A1 (en) | 2014-10-08 |
| KR20140097419A (ko) | 2014-08-06 |
| CN104023733A (zh) | 2014-09-03 |
| BR112014012880A2 (pt) | 2017-06-13 |
| MX2014006511A (es) | 2014-12-05 |
| US11554166B2 (en) | 2023-01-17 |
| US20200338181A1 (en) | 2020-10-29 |
| US11318193B2 (en) | 2022-05-03 |
| RU2014121335A (ru) | 2016-01-27 |
| EP2785361B1 (en) | 2018-11-28 |
| JP2014533743A (ja) | 2014-12-15 |
| US20140356397A1 (en) | 2014-12-04 |
| US20230149525A1 (en) | 2023-05-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) |