AU2012255352A1 - Stereospecific synthesis process for tretinoin compounds - Google Patents

Stereospecific synthesis process for tretinoin compounds

Info

Publication number
AU2012255352A1
AU2012255352A1 AU2012255352A AU2012255352A AU2012255352A1 AU 2012255352 A1 AU2012255352 A1 AU 2012255352A1 AU 2012255352 A AU2012255352 A AU 2012255352A AU 2012255352 A AU2012255352 A AU 2012255352A AU 2012255352 A1 AU2012255352 A1 AU 2012255352A1
Authority
AU
Australia
Prior art keywords
synthesis process
stereospecific synthesis
tretinoin
compounds
tretinoin compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2012255352A
Other versions
AU2012255352B2 (en
Inventor
Qingjun Deng
Taiping GAO
Yongsheng Li
Shaohui Wang
Qiang Zhu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CHONGQING HUABANGSHENGKAI PHARM Co Ltd
Original Assignee
CHONGQING HUABANGSHENGKAI PHARM Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN201110124227.3A external-priority patent/CN102775338B/en
Application filed by CHONGQING HUABANGSHENGKAI PHARM Co Ltd filed Critical CHONGQING HUABANGSHENGKAI PHARM Co Ltd
Publication of AU2012255352A1 publication Critical patent/AU2012255352A1/en
Application granted granted Critical
Publication of AU2012255352B2 publication Critical patent/AU2012255352B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

AU2012255352A 2011-05-13 2012-05-07 Stereospecific synthesis process for tretinoin compounds Active AU2012255352B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201110124227.3 2011-05-13
CN201110124227.3A CN102775338B (en) 2011-05-13 2011-05-13 All-trans-retinoic acid synthetic method
PCT/CN2012/075130 WO2012155796A1 (en) 2011-05-13 2012-05-07 Stereospecific synthesis process for tretinoin compounds

Publications (2)

Publication Number Publication Date
AU2012255352A1 true AU2012255352A1 (en) 2013-12-05
AU2012255352B2 AU2012255352B2 (en) 2015-07-23

Family

ID=47120472

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2012255352A Active AU2012255352B2 (en) 2011-05-13 2012-05-07 Stereospecific synthesis process for tretinoin compounds

Country Status (5)

Country Link
US (1) US8835680B1 (en)
EP (1) EP2708530B1 (en)
CN (1) CN102775338B (en)
AU (1) AU2012255352B2 (en)
WO (1) WO2012155796A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104086472A (en) * 2014-06-17 2014-10-08 重庆华邦胜凯制药有限公司 Method for preparing 13-cis isotretinoin
US9919993B2 (en) 2014-09-17 2018-03-20 Emcure Pharmaceuticals Limited Process for preparation of acitrecin
CN106483202B (en) * 2015-08-25 2021-03-30 重庆华邦制药有限公司 Method for separating and measuring alitretinoin and isomers
CN111423348B (en) * 2020-04-26 2021-10-22 上海新华联制药有限公司 Isotretinoin, and preparation method and application thereof
CN114105737A (en) * 2021-11-24 2022-03-01 重庆华邦胜凯制药有限公司 Preparation method and application of intermediate of abamectin A
CN116217453B (en) * 2023-01-03 2024-02-02 万华化学集团股份有限公司 Preparation method of beta-apo-8' -carotenal

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1059900B (en) 1957-09-03 1959-06-25 Basf Ag Process for the preparation of compounds of the vitamin A series
DE1068710B (en) * 1958-08-06 1959-11-12 Badische Anilin- &. Soda-Fabrik Aktiengesellschaft, Ludwigshafen/Rhein Process for the preparation of compounds of the beta-ionylidene ethylidene series
US3932485A (en) 1974-08-28 1976-01-13 Hoffmann-La Roche Inc. Improved preparation of Wittig salt of vinyl β-ionol
US4215215A (en) 1975-08-01 1980-07-29 Hoffmann-La Roche Inc. 9-Phenyl-nonate traene compounds
US4556518A (en) * 1982-12-10 1985-12-03 Hoffmann-La Roche Inc. Preparation of 13-cis retinoic acid
DE4344148A1 (en) 1993-12-23 1995-08-24 Basf Ag Process for the preparation of 9- (Z) -retinoic acid
WO2004089887A1 (en) * 2003-04-11 2004-10-21 F. Hoffmann-La Roche Ag Process for the production of 9-cis retinoic acid
CN101774954B (en) * 2009-01-12 2013-08-07 重庆华邦胜凯制药有限公司 Method for preparing all-trans tretinoin
CN101987840B (en) 2009-08-05 2012-07-25 重庆华邦制药股份有限公司 Method for separating 5-hydroxy-4-methyl-2-5[H]-furanone

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