AU2011246021A1 - High-purity soluble thrombomodulin and method for producing same - Google Patents
High-purity soluble thrombomodulin and method for producing sameInfo
- Publication number
- AU2011246021A1 AU2011246021A1 AU2011246021A AU2011246021A AU2011246021A1 AU 2011246021 A1 AU2011246021 A1 AU 2011246021A1 AU 2011246021 A AU2011246021 A AU 2011246021A AU 2011246021 A AU2011246021 A AU 2011246021A AU 2011246021 A1 AU2011246021 A1 AU 2011246021A1
- Authority
- AU
- Australia
- Prior art keywords
- producing same
- soluble thrombomodulin
- purity soluble
- purity
- thrombomodulin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000012607 Thrombomodulin Human genes 0.000 title 1
- 108010079274 Thrombomodulin Proteins 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2010-105421 | 2010-04-30 | ||
JP2010105421 | 2010-04-30 | ||
PCT/JP2011/060348 WO2011136313A1 (en) | 2010-04-30 | 2011-04-28 | High-purity soluble thrombomodulin and method for producing same |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2011246021A1 true AU2011246021A1 (en) | 2012-11-22 |
AU2011246021B2 AU2011246021B2 (en) | 2014-03-13 |
Family
ID=44861609
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2011246021A Active AU2011246021B2 (en) | 2010-04-30 | 2011-04-28 | High-purity soluble thrombomodulin and method for producing same |
Country Status (10)
Country | Link |
---|---|
US (2) | US9127089B2 (en) |
EP (2) | EP2565269B1 (en) |
JP (3) | JP5722314B2 (en) |
KR (1) | KR101486835B1 (en) |
AU (1) | AU2011246021B2 (en) |
CA (1) | CA2796452C (en) |
NZ (1) | NZ602852A (en) |
SG (2) | SG184530A1 (en) |
TW (2) | TWI546382B (en) |
WO (1) | WO2011136313A1 (en) |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2738428B2 (en) | 1987-01-08 | 1998-04-08 | 旭化成工業株式会社 | Peptides having an action to promote the activation of protein C by thrombin |
DE3856335T2 (en) | 1987-01-08 | 2000-01-27 | Asahi Chemical Ind | PEPTIDE FOR ACCELERATING THE EFFECT OF PROTEIN-C WITH THROMBIN |
DK299087D0 (en) | 1987-06-12 | 1987-06-12 | Novo Industri As | PROTEINS AND DERIVATIVES THEREOF |
EP0356395A3 (en) | 1988-08-26 | 1991-09-04 | Ciba-Geigy Ag | Flanking peptides and process for their preparation |
JPH0720997B2 (en) | 1988-08-29 | 1995-03-08 | 興和株式会社 | Novel thrombin-binding substance and method for producing the same |
JPH0798840B2 (en) | 1988-12-27 | 1995-10-25 | 持田製薬株式会社 | Urine-derived anti-blood pseudo-substance, method for producing the same, and pharmaceutical composition containing the same |
US5202421A (en) | 1988-12-27 | 1993-04-13 | Mochida Pharmaceutical Co., Ltd. | Anticoagulant substance obtained from urine and process for the preparation thereof |
JPH02255699A (en) | 1989-03-28 | 1990-10-16 | Asahi Chem Ind Co Ltd | New anticoagulant and preparation thereof |
US5466668A (en) | 1989-04-28 | 1995-11-14 | Schering Aktiengesellschaft | Superior thrombomodulin analogs for pharmaceutical use |
US6063763A (en) | 1989-04-28 | 2000-05-16 | Schering Aktiengesellschaft | Protease-resistant thrombomodulin analogs |
CA2022713A1 (en) | 1989-08-11 | 1991-02-12 | Nils U. Bang | Human thrombomodulin derivatives |
WO1991005803A1 (en) | 1989-10-18 | 1991-05-02 | Daiichi Pharmaceutical Co., Ltd. | Recombinant human thrombomodulin |
JPH03259084A (en) | 1990-03-06 | 1991-11-19 | Kowa Co | Production of thrombin-binding substance |
EP0489180A4 (en) | 1990-06-27 | 1993-03-31 | Mochida Pharmaceutical Co., Ltd. | Anticoagulant polypeptides |
JPH05213998A (en) | 1990-08-03 | 1993-08-24 | Asahi Chem Ind Co Ltd | New polypeptide and medicinal composition containing the same as active ingredient |
KR930008093B1 (en) | 1990-08-03 | 1993-08-25 | 아사히가세이고오교 가부시끼가이샤 | New polypeptide and its composition |
ES2170747T3 (en) | 1990-08-15 | 2002-08-16 | Paion Gmbh | SUPERIOR THROMBOMODULIN ANALOGS FOR PHARMACEUTICAL USE. |
JP3220174B2 (en) | 1990-12-12 | 2001-10-22 | 第一製薬株式会社 | Recombinant human thrombomodulin derivative |
PT641215E (en) | 1992-02-05 | 2004-09-30 | Paion Gmbh | PROTEASE RESISTANT TROMBOMODULIN ANALOGS |
JPH05310787A (en) | 1992-05-01 | 1993-11-22 | Asahi Chem Ind Co Ltd | New polypeptide |
JPH0646219A (en) | 1992-07-23 | 1994-02-18 | Ricoh Co Ltd | Picture information reader |
US5378816A (en) | 1992-12-16 | 1995-01-03 | Berlex Laboratories, Inc. | Methods for high purity chromatographic separation of proteins having EGF-like binding domains |
JP3439503B2 (en) | 1993-06-28 | 2003-08-25 | 旭化成株式会社 | Protein separation and purification method |
US5834028A (en) | 1993-12-17 | 1998-11-10 | Mochida Pharmaceutical Co., Ltd. | Soluble thrombomodulin-containing composition |
JP2824392B2 (en) | 1994-05-31 | 1998-11-11 | 旭化成工業株式会社 | Culture supernatant containing a peptide having an action of promoting the activation of protein C by thrombin |
JPH08280384A (en) | 1995-04-18 | 1996-10-29 | Toyobo Co Ltd | Recovery of nucleic acid or protein from sample containing nuclear cell |
JP3745805B2 (en) * | 1995-10-24 | 2006-02-15 | 日本ケミカルリサーチ株式会社 | Purification method of thrombomodulin |
JP4157644B2 (en) | 1998-03-30 | 2008-10-01 | 旭化成ファーマ株式会社 | Method for producing high-purity soluble thrombomodulin |
FR2810667B1 (en) | 2000-06-23 | 2004-09-03 | Warner Lambert Co | PROCESS FOR ISOLATING AND PURIFYING PROTEIN, AND PROTEIN OBTAINED |
GB0100513D0 (en) | 2001-01-09 | 2001-02-21 | Smithkline Beecham Plc | Process |
US20060083733A1 (en) | 2002-01-18 | 2006-04-20 | Fumihide Nishio | High-concentration preparation of soluble thrombomodulin |
JP2007016016A (en) | 2005-06-09 | 2007-01-25 | Toray Ind Inc | Method and device for fractionation |
WO2007035283A1 (en) | 2005-09-15 | 2007-03-29 | Wyeth | Protein floculation using salts |
SG184699A1 (en) | 2007-03-23 | 2012-10-30 | Asahi Kasei Pharma Corp | Method for producing high-purity soluble thrombomodulin |
FR2920429B1 (en) | 2007-08-30 | 2012-10-05 | Lfb Biotechnologies | PROCESS FOR PURIFYING FACTOR VIII AND VON WILLEBRAND FACTOR |
JP2010051927A (en) | 2008-08-29 | 2010-03-11 | Asahi Kasei Corp | Method of separating biogenic substance using ultra-filtration membrane, module and device |
-
2011
- 2011-04-28 EP EP11775094.3A patent/EP2565269B1/en active Active
- 2011-04-28 KR KR20127030333A patent/KR101486835B1/en active IP Right Grant
- 2011-04-28 NZ NZ60285211A patent/NZ602852A/en unknown
- 2011-04-28 WO PCT/JP2011/060348 patent/WO2011136313A1/en active Application Filing
- 2011-04-28 EP EP16193734.7A patent/EP3150628A1/en not_active Withdrawn
- 2011-04-28 SG SG2012075115A patent/SG184530A1/en unknown
- 2011-04-28 JP JP2012512902A patent/JP5722314B2/en active Active
- 2011-04-28 AU AU2011246021A patent/AU2011246021B2/en active Active
- 2011-04-28 TW TW100114937A patent/TWI546382B/en active
- 2011-04-28 SG SG10201500036WA patent/SG10201500036WA/en unknown
- 2011-04-28 CA CA2796452A patent/CA2796452C/en active Active
- 2011-04-28 TW TW104103941A patent/TW201522633A/en unknown
- 2011-04-28 US US13/641,047 patent/US9127089B2/en active Active
-
2015
- 2015-01-07 JP JP2015001499A patent/JP5873578B2/en active Active
- 2015-07-28 US US14/811,572 patent/US20150322133A1/en not_active Abandoned
- 2015-10-13 JP JP2015201714A patent/JP2016014067A/en not_active Withdrawn
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