AU2011246021A1 - High-purity soluble thrombomodulin and method for producing same - Google Patents

High-purity soluble thrombomodulin and method for producing same

Info

Publication number
AU2011246021A1
AU2011246021A1 AU2011246021A AU2011246021A AU2011246021A1 AU 2011246021 A1 AU2011246021 A1 AU 2011246021A1 AU 2011246021 A AU2011246021 A AU 2011246021A AU 2011246021 A AU2011246021 A AU 2011246021A AU 2011246021 A1 AU2011246021 A1 AU 2011246021A1
Authority
AU
Australia
Prior art keywords
producing same
soluble thrombomodulin
purity soluble
purity
thrombomodulin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU2011246021A
Other versions
AU2011246021B2 (en
Inventor
Hiroki Shigematsu
Yuji Ueno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Pharma Corp
Original Assignee
Asahi Kasei Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Kasei Pharma Corp filed Critical Asahi Kasei Pharma Corp
Priority claimed from PCT/JP2011/060348 external-priority patent/WO2011136313A1/en
Publication of AU2011246021A1 publication Critical patent/AU2011246021A1/en
Application granted granted Critical
Publication of AU2011246021B2 publication Critical patent/AU2011246021B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

AU2011246021A 2010-04-30 2011-04-28 High-purity soluble thrombomodulin and method for producing same Active AU2011246021B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2010-105421 2010-04-30
JP2010105421 2010-04-30
PCT/JP2011/060348 WO2011136313A1 (en) 2010-04-30 2011-04-28 High-purity soluble thrombomodulin and method for producing same

Publications (2)

Publication Number Publication Date
AU2011246021A1 true AU2011246021A1 (en) 2012-11-22
AU2011246021B2 AU2011246021B2 (en) 2014-03-13

Family

ID=44861609

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2011246021A Active AU2011246021B2 (en) 2010-04-30 2011-04-28 High-purity soluble thrombomodulin and method for producing same

Country Status (10)

Country Link
US (2) US9127089B2 (en)
EP (2) EP2565269B1 (en)
JP (3) JP5722314B2 (en)
KR (1) KR101486835B1 (en)
AU (1) AU2011246021B2 (en)
CA (1) CA2796452C (en)
NZ (1) NZ602852A (en)
SG (2) SG184530A1 (en)
TW (2) TWI546382B (en)
WO (1) WO2011136313A1 (en)

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2738428B2 (en) 1987-01-08 1998-04-08 旭化成工業株式会社 Peptides having an action to promote the activation of protein C by thrombin
DE3856335T2 (en) 1987-01-08 2000-01-27 Asahi Chemical Ind PEPTIDE FOR ACCELERATING THE EFFECT OF PROTEIN-C WITH THROMBIN
DK299087D0 (en) 1987-06-12 1987-06-12 Novo Industri As PROTEINS AND DERIVATIVES THEREOF
EP0356395A3 (en) 1988-08-26 1991-09-04 Ciba-Geigy Ag Flanking peptides and process for their preparation
JPH0720997B2 (en) 1988-08-29 1995-03-08 興和株式会社 Novel thrombin-binding substance and method for producing the same
JPH0798840B2 (en) 1988-12-27 1995-10-25 持田製薬株式会社 Urine-derived anti-blood pseudo-substance, method for producing the same, and pharmaceutical composition containing the same
US5202421A (en) 1988-12-27 1993-04-13 Mochida Pharmaceutical Co., Ltd. Anticoagulant substance obtained from urine and process for the preparation thereof
JPH02255699A (en) 1989-03-28 1990-10-16 Asahi Chem Ind Co Ltd New anticoagulant and preparation thereof
US5466668A (en) 1989-04-28 1995-11-14 Schering Aktiengesellschaft Superior thrombomodulin analogs for pharmaceutical use
US6063763A (en) 1989-04-28 2000-05-16 Schering Aktiengesellschaft Protease-resistant thrombomodulin analogs
CA2022713A1 (en) 1989-08-11 1991-02-12 Nils U. Bang Human thrombomodulin derivatives
WO1991005803A1 (en) 1989-10-18 1991-05-02 Daiichi Pharmaceutical Co., Ltd. Recombinant human thrombomodulin
JPH03259084A (en) 1990-03-06 1991-11-19 Kowa Co Production of thrombin-binding substance
EP0489180A4 (en) 1990-06-27 1993-03-31 Mochida Pharmaceutical Co., Ltd. Anticoagulant polypeptides
JPH05213998A (en) 1990-08-03 1993-08-24 Asahi Chem Ind Co Ltd New polypeptide and medicinal composition containing the same as active ingredient
KR930008093B1 (en) 1990-08-03 1993-08-25 아사히가세이고오교 가부시끼가이샤 New polypeptide and its composition
ES2170747T3 (en) 1990-08-15 2002-08-16 Paion Gmbh SUPERIOR THROMBOMODULIN ANALOGS FOR PHARMACEUTICAL USE.
JP3220174B2 (en) 1990-12-12 2001-10-22 第一製薬株式会社 Recombinant human thrombomodulin derivative
PT641215E (en) 1992-02-05 2004-09-30 Paion Gmbh PROTEASE RESISTANT TROMBOMODULIN ANALOGS
JPH05310787A (en) 1992-05-01 1993-11-22 Asahi Chem Ind Co Ltd New polypeptide
JPH0646219A (en) 1992-07-23 1994-02-18 Ricoh Co Ltd Picture information reader
US5378816A (en) 1992-12-16 1995-01-03 Berlex Laboratories, Inc. Methods for high purity chromatographic separation of proteins having EGF-like binding domains
JP3439503B2 (en) 1993-06-28 2003-08-25 旭化成株式会社 Protein separation and purification method
US5834028A (en) 1993-12-17 1998-11-10 Mochida Pharmaceutical Co., Ltd. Soluble thrombomodulin-containing composition
JP2824392B2 (en) 1994-05-31 1998-11-11 旭化成工業株式会社 Culture supernatant containing a peptide having an action of promoting the activation of protein C by thrombin
JPH08280384A (en) 1995-04-18 1996-10-29 Toyobo Co Ltd Recovery of nucleic acid or protein from sample containing nuclear cell
JP3745805B2 (en) * 1995-10-24 2006-02-15 日本ケミカルリサーチ株式会社 Purification method of thrombomodulin
JP4157644B2 (en) 1998-03-30 2008-10-01 旭化成ファーマ株式会社 Method for producing high-purity soluble thrombomodulin
FR2810667B1 (en) 2000-06-23 2004-09-03 Warner Lambert Co PROCESS FOR ISOLATING AND PURIFYING PROTEIN, AND PROTEIN OBTAINED
GB0100513D0 (en) 2001-01-09 2001-02-21 Smithkline Beecham Plc Process
US20060083733A1 (en) 2002-01-18 2006-04-20 Fumihide Nishio High-concentration preparation of soluble thrombomodulin
JP2007016016A (en) 2005-06-09 2007-01-25 Toray Ind Inc Method and device for fractionation
WO2007035283A1 (en) 2005-09-15 2007-03-29 Wyeth Protein floculation using salts
SG184699A1 (en) 2007-03-23 2012-10-30 Asahi Kasei Pharma Corp Method for producing high-purity soluble thrombomodulin
FR2920429B1 (en) 2007-08-30 2012-10-05 Lfb Biotechnologies PROCESS FOR PURIFYING FACTOR VIII AND VON WILLEBRAND FACTOR
JP2010051927A (en) 2008-08-29 2010-03-11 Asahi Kasei Corp Method of separating biogenic substance using ultra-filtration membrane, module and device

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