AU2010330812B2 - Methods and compositions for treating inflammation of skin - Google Patents

Methods and compositions for treating inflammation of skin Download PDF

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Publication number
AU2010330812B2
AU2010330812B2 AU2010330812A AU2010330812A AU2010330812B2 AU 2010330812 B2 AU2010330812 B2 AU 2010330812B2 AU 2010330812 A AU2010330812 A AU 2010330812A AU 2010330812 A AU2010330812 A AU 2010330812A AU 2010330812 B2 AU2010330812 B2 AU 2010330812B2
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AU
Australia
Prior art keywords
oil
composition
doxepin
agent
antihistamine
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Ceased
Application number
AU2010330812A
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English (en)
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AU2010330812A1 (en
AU2010330812A2 (en
Inventor
Crist J. Frangakis
Harry J. Leighton
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Exodos Life Sciences LP
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Exodos Life Sciences LP
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Publication of AU2010330812A1 publication Critical patent/AU2010330812A1/en
Publication of AU2010330812A2 publication Critical patent/AU2010330812A2/en
Application granted granted Critical
Publication of AU2010330812B2 publication Critical patent/AU2010330812B2/en
Ceased legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534—Mentha (mint)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2010330812A 2009-12-18 2010-12-17 Methods and compositions for treating inflammation of skin Ceased AU2010330812B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28798009P 2009-12-18 2009-12-18
US61/287,980 2009-12-18
PCT/US2010/061051 WO2011075654A1 (en) 2009-12-18 2010-12-17 Methods and compositions for treating inflammation of skin

Publications (3)

Publication Number Publication Date
AU2010330812A1 AU2010330812A1 (en) 2012-08-09
AU2010330812A2 AU2010330812A2 (en) 2012-08-16
AU2010330812B2 true AU2010330812B2 (en) 2016-03-10

Family

ID=44167717

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010330812A Ceased AU2010330812B2 (en) 2009-12-18 2010-12-17 Methods and compositions for treating inflammation of skin

Country Status (6)

Country Link
US (1) US20130059019A1 (enExample)
EP (1) EP2513343A4 (enExample)
JP (1) JP5944325B2 (enExample)
AU (1) AU2010330812B2 (enExample)
CA (1) CA2784785A1 (enExample)
WO (1) WO2011075654A1 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2512460A4 (en) 2009-12-18 2015-01-21 Exodos Life Sciences Ltd Partnership METHOD AND COMPOSITIONS FOR STABLE LIQUID ACTIVE FORMULATIONS
WO2014028780A2 (en) * 2012-08-15 2014-02-20 Nexmed Holdings, Inc. Antifungal compounds and methods of use
WO2014059008A1 (en) 2012-10-09 2014-04-17 The Procter & Gamble Company Method of identifying or evaluating beneficial actives and compositions containing the same
CN104703585A (zh) 2012-10-09 2015-06-10 宝洁公司 鉴定协同化妆品组合的方法
US10471064B2 (en) * 2013-01-29 2019-11-12 Lily Hsiao Medicament for treating peripheral neuropathies
US9144538B2 (en) 2013-02-08 2015-09-29 The Procter & Gamble Company Cosmetic compositions containing substituted azole and methods for alleviating the signs of photoaged skin
US9138393B2 (en) 2013-02-08 2015-09-22 The Procter & Gamble Company Cosmetic compositions containing substituted azole and methods for improving the appearance of aging skin
US8883747B1 (en) 2013-10-09 2014-11-11 Craig W. Carver Topical antifungal compositions and methods of use thereof
WO2015120412A1 (en) * 2014-02-07 2015-08-13 The Johns Hopkins University Compositions and methods for controlling fungal growth
US20170182040A1 (en) * 2014-05-02 2017-06-29 The Board Of Trustees Of The Leland Stanford Junior University Epithelial ion channel (enac) blockers to treat psoriasis
WO2016057513A1 (en) * 2014-10-10 2016-04-14 Monibi Regina Topical skin care formulation
EP3226972A4 (en) 2014-12-01 2018-08-08 Achelios Therapeutics, Inc. Methods and compositions for treating migraine and conditions associated with pain
WO2017007668A1 (en) * 2015-07-08 2017-01-12 Elliptical Therapeutics, Llc Improved topical ketoprofen formulations
US10286095B2 (en) 2015-09-11 2019-05-14 Olson Ip Technologies, Inc. Travel kit
WO2017130638A1 (ja) * 2016-01-28 2017-08-03 花王株式会社 アストロサイトのグルコース代謝活性化剤
JP6735224B2 (ja) 2016-01-28 2020-08-05 花王株式会社 アストロサイトのグルコース代謝活性化剤
KR101873218B1 (ko) * 2016-07-29 2018-07-03 코스맥스 주식회사 홀리바질, 박하, 님나무 추출 혼합물을 유효성분으로 함유하는 미세먼지에 의한 피부자극 및 피부염증 완화용 조성물
DE102017215154A1 (de) * 2017-08-30 2019-02-28 Markus Bläss Zusammensetzung zur topischen Behandlung von nicht-Mikroorganismus-verursachten entzündlichen Haut- und Schleimhauterkrankungen
AU2018399939A1 (en) * 2018-01-02 2020-07-09 Nal Pharmaceutical Group Limited Semi-solid dosage form for topical application
CN113750126A (zh) * 2021-09-30 2021-12-07 梵申兰科技(上海)有限公司 一种治疗皮肤疱疹的青蒿精油、白茶精油及它们的组合物
WO2023063902A1 (en) * 2021-10-14 2023-04-20 Istanbul Medipol Universitesi Teknoloji Transfer Ofisi Anonim Sirketi Microemulsion formulations developed for wound-burn treatment
KR20230115035A (ko) * 2022-01-26 2023-08-02 (주)유스케어팜 타이바질, 물엉겅퀴 및 눈개승마의 복합추출물을 유효성분으로 포함하는 염증질환 예방 또는 치료용 조성물
US12465645B2 (en) * 2022-04-01 2025-11-11 Alexia Reif Anti-viral composition and method for preparing the same

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2179552A (en) * 1985-08-27 1987-03-11 Univ Dundee Medicaments containing mepyramine
US4748022A (en) * 1985-03-25 1988-05-31 Busciglio John A Topical composition
US20060229364A1 (en) * 2005-03-10 2006-10-12 3M Innovative Properties Company Antiviral compositions and methods of use
US20090304826A1 (en) * 2008-05-30 2009-12-10 Fairfield Clinical Trials, Llc Method and composition for dermatoses

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US4185100A (en) * 1976-05-13 1980-01-22 Johnson & Johnson Topical anti-inflammatory drug therapy
US4256763A (en) * 1978-09-19 1981-03-17 Mchugh John E Treatment of herpes simplex infections and acne
US4499084A (en) * 1983-02-03 1985-02-12 Dixon Glen J Ara-A Antiviral composition and method of administering the same
US4914131A (en) * 1984-03-08 1990-04-03 Dana P. Brigham Antiviral pharmaceutical preparations and methods for their use
NL9500216A (nl) * 1995-02-06 1996-09-02 Bio Pharma Sciences Bv Farmaceutische samenstelling voor de behandeling van herpes.
AU9692898A (en) * 1997-10-17 1999-05-10 Eli Lilly And Company Potentiation of pharmaceuticals
US6967023B1 (en) * 2000-01-10 2005-11-22 Foamix, Ltd. Pharmaceutical and cosmetic carrier or composition for topical application
CA2518329C (en) * 2003-03-12 2015-11-24 Epitome Pharmaceuticals Limited Rapidly absorbing lipophilic skin compositions and uses therefor
US20050118261A1 (en) * 2003-06-12 2005-06-02 Oien Hal J. Compositions and methods of administering doxepin to mucosal tissue
JP5011739B2 (ja) * 2005-02-03 2012-08-29 アステラス製薬株式会社 テトラヒドロ−２ｈ−チオピラン−４−カルボキサミド誘導体を含有する医薬組成物
TW200711649A (en) * 2005-06-17 2007-04-01 Combinatorx Inc Combination therapy for the treatment of immunoinflammatory disorders
ITRM20060163A1 (it) * 2006-03-24 2007-09-25 Ist Farmacoterapico It Spa Composizione spray ad uso topico per il tratamento e la prevenzione delle infezioni labiali da herpes simplex
US8450330B2 (en) * 2007-08-29 2013-05-28 Yung Shin Pharmaceutical Industrial Co., Ltd. Pharmaceutical acceptable composition containing non-steroidal anti-inflammatory drug and local anesthetics

Patent Citations (4)

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Publication number Priority date Publication date Assignee Title
US4748022A (en) * 1985-03-25 1988-05-31 Busciglio John A Topical composition
GB2179552A (en) * 1985-08-27 1987-03-11 Univ Dundee Medicaments containing mepyramine
US20060229364A1 (en) * 2005-03-10 2006-10-12 3M Innovative Properties Company Antiviral compositions and methods of use
US20090304826A1 (en) * 2008-05-30 2009-12-10 Fairfield Clinical Trials, Llc Method and composition for dermatoses

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Title
KURZROCK R, et al., Clinical and Experimental Dermatology, (1987) Vol 12, pp 326-331. *
PATOU G, et al., Biol Psychiatry, (1986) Vol 21, pp 1221-1225. *

Also Published As

Publication number Publication date
EP2513343A1 (en) 2012-10-24
JP5944325B2 (ja) 2016-07-05
AU2010330812A1 (en) 2012-08-09
AU2010330812A2 (en) 2012-08-16
EP2513343A4 (en) 2013-11-13
JP2013514994A (ja) 2013-05-02
WO2011075654A1 (en) 2011-06-23
CA2784785A1 (en) 2011-06-23
US20130059019A1 (en) 2013-03-07

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