AU2010295497B2 - Immunological compositions for HIV - Google Patents

Immunological compositions for HIV Download PDF

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Publication number
AU2010295497B2
AU2010295497B2 AU2010295497A AU2010295497A AU2010295497B2 AU 2010295497 B2 AU2010295497 B2 AU 2010295497B2 AU 2010295497 A AU2010295497 A AU 2010295497A AU 2010295497 A AU2010295497 A AU 2010295497A AU 2010295497 B2 AU2010295497 B2 AU 2010295497B2
Authority
AU
Australia
Prior art keywords
hiv
composition
kit
polypeptide
dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2010295497A
Other languages
English (en)
Other versions
AU2010295497A1 (en
Inventor
Don Francis
Sanjay Gurunathan
Jerome H. Kim
Supachai Rerks-Ngarm
James T. Tartaglia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MINISTRY OF PUBLIC HEALTH
GLOBAL SOLUTIONS FOR INFECTIOUS DISEASES
SANOFI PASTEUR Inc
Walter Reed Army Institute of Research
Original Assignee
Mini Of Public Health
GLOBAL SOLUTIONS FOR INFECTIOUS DISEASES
SANOFI PASTEUR Inc
Walter Reed Army Institute of Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mini Of Public Health, GLOBAL SOLUTIONS FOR INFECTIOUS DISEASES, SANOFI PASTEUR Inc, Walter Reed Army Institute of Research filed Critical Mini Of Public Health
Publication of AU2010295497A1 publication Critical patent/AU2010295497A1/en
Application granted granted Critical
Publication of AU2010295497B2 publication Critical patent/AU2010295497B2/en
Priority to AU2015200094A priority Critical patent/AU2015200094A1/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/24043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AU2010295497A 2009-09-17 2010-09-17 Immunological compositions for HIV Ceased AU2010295497B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2015200094A AU2015200094A1 (en) 2009-09-17 2015-01-09 Immunological compositions for HIV

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24352209P 2009-09-17 2009-09-17
US61/243,522 2009-09-17
PCT/US2010/049206 WO2011035082A1 (en) 2009-09-17 2010-09-17 Immunological compositions for hiv

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2015200094A Division AU2015200094A1 (en) 2009-09-17 2015-01-09 Immunological compositions for HIV

Publications (2)

Publication Number Publication Date
AU2010295497A1 AU2010295497A1 (en) 2012-04-19
AU2010295497B2 true AU2010295497B2 (en) 2014-10-09

Family

ID=43086913

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010295497A Ceased AU2010295497B2 (en) 2009-09-17 2010-09-17 Immunological compositions for HIV

Country Status (6)

Country Link
US (1) US20120308593A1 (enExample)
EP (2) EP2477651A1 (enExample)
JP (3) JP2013505256A (enExample)
AU (1) AU2010295497B2 (enExample)
CA (1) CA2774154A1 (enExample)
WO (1) WO2011035082A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10040826B2 (en) 2011-07-05 2018-08-07 Duke University Human immunodeficiency virus type 1 (HIV-1) N-terminal deleted GP120 immunogens
EP2763699A4 (en) 2011-10-03 2015-05-20 Univ Duke VACCINE
EP2620446A1 (en) 2012-01-27 2013-07-31 Laboratorios Del Dr. Esteve, S.A. Immunogens for HIV vaccination
JP6491095B2 (ja) 2012-09-12 2019-04-03 デューク ユニバーシティ 抗体進化免疫原
US10906941B2 (en) 2013-04-15 2021-02-02 Duke University Methods of inducing an immune response against HIV-1 using recombinant envelopes with improved coverage
WO2015160726A2 (en) * 2014-04-14 2015-10-22 Indiana University Research And Technology Corporation A generalizable assay for virus capsid assembly
CN113924114A (zh) 2019-05-22 2022-01-11 吉利德科学公司 Tlr7调节化合物和hiv疫苗的组合
AU2020384323A1 (en) 2019-11-14 2022-06-02 Aelix Therapeutics, S.L. Dosage regimens for vaccines

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001054701A1 (en) * 2000-01-31 2001-08-02 Aventis Pasteur, S.A. Vaccination of hiv infected persons following highly active antiretroviral therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1278541A1 (en) * 2000-04-28 2003-01-29 The Government of The United States of America, as represented by The Department of Health and Human Services Improved immunogenicity using a combination of dna and vaccinia virus vector vaccines

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001054701A1 (en) * 2000-01-31 2001-08-02 Aventis Pasteur, S.A. Vaccination of hiv infected persons following highly active antiretroviral therapy

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
BELSHE R. B., et al, The Journal of Infectious Diseases, 2001, vol 183, no 9, pages 1343-1352 *
BOGERS W. M. J. M., et al, "Systemic neutralising antibodies induced by long interval mucosally primed systemically boosted immunization correlate with protection from mucosal SHIV challenge", Virology, 2008, vol 382, no 2, pages 217-225 *
DOEPEL L. K: "Combination HIV vaccine induces diverse immune responses", NIH news release, 13 July 1999. Retrieved from internet: http://www.nih.gov/news/pr/jul99/niaid-13.htm [retrieved on 4 February 2013] *
GOMEZ-ROMAN V. R., et al, Journal of Acquired Immune Deficiency Syndromes, 2006, vol 43, no 3, pages 270-277 *
GOMEZ-ROMAN V. R., et al, The Journal of Immunology, 2005, vol 174, no 4, pages 2185-2189 *
JOHNSTON M. I., et al, "Progress in HIV vaccine development", Current Opinion in Pharmacology, 2001, vol 1, no 5, pages 504-510 *
PENG B., et al, Journal of Virology, 2005, vol 79, no 16, pages 10200-10209 *
RERKS-NGARM S., et al, "Phase III trial of HIV prime-boost vaccine combination in Thailand: Follow up phase", AIDS research and human retroviruses, 2008, vol 24, supplement 1, page 101 *
RUSSELL N. D., et al, "Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120", Journal of Acquired Immune Deficiency Syndromes, 2007, vol 44, no 2, pages 203-212 *
The AIDS Vaccine Evaluation Group 022 Protocol, The Journal of Infectious Diseases, 2001, vol 183, pages 563-570 *
THONGCHAROEN P., et al, "A phase 1/2 comparative vaccine trial of the safety and immunogenicity of a CRF01_AE (subtype E) candidate vaccine", Journal of Acquired Immune Deficiency Syndromes, 2007, vol 46, no 1, pages 48-55 *

Also Published As

Publication number Publication date
WO2011035082A1 (en) 2011-03-24
JP2018039832A (ja) 2018-03-15
CA2774154A1 (en) 2011-03-24
EP2987500A1 (en) 2016-02-24
EP2477651A1 (en) 2012-07-25
JP2016074727A (ja) 2016-05-12
JP2013505256A (ja) 2013-02-14
US20120308593A1 (en) 2012-12-06
AU2010295497A1 (en) 2012-04-19
JP6619788B2 (ja) 2019-12-11

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired