AU2009205539B2 - Substitued-aryl-(imidazole)-methyl)-phenyl compounds as subtype selective modulators of alpha 2B and/or alpha 2C adrenergic receptors - Google Patents
Substitued-aryl-(imidazole)-methyl)-phenyl compounds as subtype selective modulators of alpha 2B and/or alpha 2C adrenergic receptors Download PDFInfo
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- AU2009205539B2 AU2009205539B2 AU2009205539A AU2009205539A AU2009205539B2 AU 2009205539 B2 AU2009205539 B2 AU 2009205539B2 AU 2009205539 A AU2009205539 A AU 2009205539A AU 2009205539 A AU2009205539 A AU 2009205539A AU 2009205539 B2 AU2009205539 B2 AU 2009205539B2
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| US2214808P | 2008-01-18 | 2008-01-18 | |
| US61/022,148 | 2008-01-18 | ||
| PCT/US2009/030849 WO2009091735A1 (en) | 2008-01-18 | 2009-01-13 | Substitued-aryl-(imidazole)-methyl)-phenyl compounds as subtype selective modulators of alpha 2b and/or alpha 2c adrenergic receptors |
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| AU2009205539B2 true AU2009205539B2 (en) | 2013-12-05 |
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| US7902247B2 (en) * | 2008-01-09 | 2011-03-08 | Allergan, Inc. | Substituted-aryl-2-phenylethyl-1H-imidazole compounds as subtype selective modulators of alpha 2B and/or alpha 2C adrenergic receptors |
| CA2888485C (en) | 2012-10-16 | 2021-01-26 | Janssen Pharmaceutica Nv | Phenyl linked quinolinyl modulators of ror.gamma.t |
| MY189505A (en) | 2012-10-16 | 2022-02-16 | Janssen Pharmaceutica Nv | Methylene linked quinolinyl modulators of roryt |
| ES2619610T3 (es) | 2012-10-16 | 2017-06-26 | Janssen Pharmaceutica Nv | Moduladores de ROR-gamma-t de quinolinilo enlazado con heteroarilo |
| US9403816B2 (en) | 2013-10-15 | 2016-08-02 | Janssen Pharmaceutica Nv | Phenyl linked quinolinyl modulators of RORγt |
| US10555941B2 (en) | 2013-10-15 | 2020-02-11 | Janssen Pharmaceutica Nv | Alkyl linked quinolinyl modulators of RORγt |
| BR112016008215A2 (pt) | 2013-10-15 | 2017-09-26 | Janssen Pharmaceutica Nv | moduladores de quinolinila ligados por alquila de roryt |
| US9221804B2 (en) | 2013-10-15 | 2015-12-29 | Janssen Pharmaceutica Nv | Secondary alcohol quinolinyl modulators of RORγt |
| US9284308B2 (en) | 2013-10-15 | 2016-03-15 | Janssen Pharmaceutica Nv | Methylene linked quinolinyl modulators of RORγt |
| US9328095B2 (en) | 2013-10-15 | 2016-05-03 | Janssen Pharmaceutica Nv | Heteroaryl linked quinolinyl modulators of RORgammat |
| ES2742843T3 (es) | 2013-10-15 | 2020-02-17 | Janssen Pharmaceutica Nv | Moduladores de quinolinilo de ROR(gamma)t |
| JP2019517524A (ja) * | 2016-06-02 | 2019-06-24 | パーデュー ファーマ エルピー | 疼痛治療のための微量アミン関連受容体１アゴニスト及び部分アゴニスト |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4661508A (en) * | 1984-06-18 | 1987-04-28 | Eli Lilly And Company | Aromatase inhibiting α,α-diphenyl-4(5)imidazole-methanes or -ethanes |
| WO2007085556A2 (en) * | 2006-01-27 | 2007-08-02 | F. Hoffmann-La Roche Ag | Use of 4-imidazole derivatives for cns disorders |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR206507A1 (es) | 1972-10-13 | 1976-07-30 | Ciba Geigy Ag | Procedimiento para la obtencion de nuevos 4-eteres de acidos 3-amino-5-sulfamoilbenzoicos |
| GB2101114B (en) * | 1981-07-10 | 1985-05-22 | Farmos Group Ltd | Substituted imidazole derivatives and their preparation and use |
| CA1238640A (en) * | 1984-06-18 | 1988-06-28 | Kenneth S. Hirsch | 4(5)-substituted imidazoles |
| DE69520430T2 (de) | 1994-06-03 | 2001-10-18 | The Jmde Trust, Newton | Meta substituierte arylalkylamine und therapeutische und diagnostische verwendung davon |
| JP4783502B2 (ja) * | 1997-12-04 | 2011-09-28 | アラーガン、インコーポレイテッド | α２Ｂまたは２Ｂ／２Ｃアドレナリン受容体において作動剤様活性を示す置換イミダゾール誘導体 |
| TWI283669B (en) | 1999-06-10 | 2007-07-11 | Allergan Inc | Compounds and method of treatment having agonist-like activity selective at alpha 2B or 2B/2C adrenergic receptors |
| ES2402746T3 (es) * | 2007-05-14 | 2013-05-08 | Allergan, Inc. | Compuestos de (fenil)(imidazolil)metilheteroarilo |
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2009
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2012
- 2012-04-24 US US13/454,259 patent/US20120202865A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4661508A (en) * | 1984-06-18 | 1987-04-28 | Eli Lilly And Company | Aromatase inhibiting α,α-diphenyl-4(5)imidazole-methanes or -ethanes |
| WO2007085556A2 (en) * | 2006-01-27 | 2007-08-02 | F. Hoffmann-La Roche Ag | Use of 4-imidazole derivatives for cns disorders |
Non-Patent Citations (2)
| Title |
|---|
| KANETO HIROSHI ET AL: "General pharmacological properties of bifonazole and its decomposition products and by-products" OYO YAKURI - PHARMACOMETRICS" vo1. 27, no. 5, 1 January 1984 (1984-01-01), pages 885-897, XP009116710 ISSN: 0300-8533 * |
| KARJALAINEN A ET AL: "Synthesis of new potent and selective aromatase inhibitors based on long-chained diarylalkylimidazole and diarylalkyltriazole molecule skeletons" 1 January 2000 (2000-01- 01), EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCE * |
Also Published As
| Publication number | Publication date |
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| EP2250153A1 (en) | 2010-11-17 |
| US20110098330A1 (en) | 2011-04-28 |
| JP2011522774A (ja) | 2011-08-04 |
| US20120202865A1 (en) | 2012-08-09 |
| AU2009205539A1 (en) | 2009-07-23 |
| ES2421896T3 (es) | 2013-09-06 |
| US8227499B2 (en) | 2012-07-24 |
| BRPI0906927A2 (pt) | 2015-07-21 |
| WO2009091735A1 (en) | 2009-07-23 |
| JP5453312B2 (ja) | 2014-03-26 |
| CA2712256A1 (en) | 2009-07-23 |
| DK2250153T3 (da) | 2013-09-16 |
| EP2250153B1 (en) | 2013-06-19 |
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