AU2008328588B2 - Electrochemical detection of a metal - labelled analyte - Google Patents

Electrochemical detection of a metal - labelled analyte Download PDF

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Publication number
AU2008328588B2
AU2008328588B2 AU2008328588A AU2008328588A AU2008328588B2 AU 2008328588 B2 AU2008328588 B2 AU 2008328588B2 AU 2008328588 A AU2008328588 A AU 2008328588A AU 2008328588 A AU2008328588 A AU 2008328588A AU 2008328588 B2 AU2008328588 B2 AU 2008328588B2
Authority
AU
Australia
Prior art keywords
metal
analyte
release agent
charged
nanoparticle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2008328588A
Other languages
English (en)
Other versions
AU2008328588A1 (en
Inventor
Robert Andrew Porter
Mateusz Szymanski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AGPLUS DIAGNOSTICS Ltd
Original Assignee
AGPLUS DIAGNOSTICS Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0723137A external-priority patent/GB0723137D0/en
Priority claimed from GB0812679A external-priority patent/GB0812679D0/en
Priority claimed from GB0812845A external-priority patent/GB2462062A/en
Application filed by AGPLUS DIAGNOSTICS Ltd filed Critical AGPLUS DIAGNOSTICS Ltd
Publication of AU2008328588A1 publication Critical patent/AU2008328588A1/en
Application granted granted Critical
Publication of AU2008328588B2 publication Critical patent/AU2008328588B2/en
Assigned to SERCO HOLDINGS LIMITED reassignment SERCO HOLDINGS LIMITED Request for Assignment Assignors: THE SECRETARY OF STATE FOR INNOVATION, UNIVERSITIES AND SKILLS OF HER MAJESTY'S BRITANNIC GOVERNMENT
Assigned to AGPLUS DIAGNOSTICS LIMITED reassignment AGPLUS DIAGNOSTICS LIMITED Request for Assignment Assignors: SERCO HOLDINGS LIMITED
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587—Nanoparticles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Secondary Cells (AREA)
AU2008328588A 2007-11-26 2008-11-25 Electrochemical detection of a metal - labelled analyte Ceased AU2008328588B2 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB0723137A GB0723137D0 (en) 2007-11-26 2007-11-26 Electrochemical assay
GB0723137.6 2007-11-26
GB0812679A GB0812679D0 (en) 2008-07-10 2008-07-10 Sample carrier for effecting chemical assays
GB0812679.9 2008-07-10
GB0812845.6 2008-07-14
GB0812845A GB2462062A (en) 2008-07-14 2008-07-14 Electrochemical assay
PCT/GB2008/003931 WO2009068862A1 (en) 2007-11-26 2008-11-25 Electrochemical detection using silver nanoparticle labelled antibodies

Publications (2)

Publication Number Publication Date
AU2008328588A1 AU2008328588A1 (en) 2009-06-04
AU2008328588B2 true AU2008328588B2 (en) 2013-09-05

Family

ID=40325792

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008328588A Ceased AU2008328588B2 (en) 2007-11-26 2008-11-25 Electrochemical detection of a metal - labelled analyte

Country Status (9)

Country Link
US (1) US8337692B2 (https=)
EP (1) EP2220494B1 (https=)
JP (1) JP5055433B2 (https=)
CN (1) CN101971029B (https=)
AT (1) ATE533054T1 (https=)
AU (1) AU2008328588B2 (https=)
GB (1) GB2458420B (https=)
NZ (1) NZ585851A (https=)
WO (1) WO2009068862A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2462062A (en) * 2008-07-14 2010-01-27 Sec Dep For Innovation Univers Electrochemical assay
JP5806892B2 (ja) 2010-09-30 2015-11-10 シスメックス株式会社 検出物質の電気化学的検出方法および被検物質の電気化学的検出方法
JP5762225B2 (ja) * 2011-09-08 2015-08-12 新留　康郎 銀シェル金ナノロッドを用いる分析方法
GB201118293D0 (en) 2011-10-24 2011-12-07 Sec Dep For Business Innovation & Skills The Electrochemical assay
GB201217390D0 (en) 2012-09-28 2012-11-14 Agplus Diagnostics Ltd Test device and sample carrier
RU2550955C1 (ru) * 2013-12-11 2015-05-20 Общество с ограниченной ответственностью "Уральский центр биофармацевтических технологий Способ электрохимического иммуноанализа для определения вирусов/антигенов вирусов
CN104181292B (zh) * 2014-08-27 2015-12-02 湖南师范大学 一种蛋白质单分子水平安培免疫分析方法
JP6486065B2 (ja) * 2014-10-28 2019-03-20 シスメックス株式会社 被検物質の検出方法
EP3292395A4 (en) 2015-04-08 2019-01-02 Board of Regents, The University of Texas System Methods and systems for the detection of analytes
WO2016167724A1 (en) * 2015-04-13 2016-10-20 Agency For Science, Technology And Research Device for electrochemical immunoassay and method of fabricating the same
CN110192140A (zh) * 2016-11-16 2019-08-30 华盛顿大学 用于循环荧光成像的系统和方法
WO2020000959A1 (zh) * 2018-06-29 2020-01-02 北京华科泰生物技术股份有限公司 一种基于标记物标记的电化学检测方法
JP7310697B2 (ja) * 2019-05-16 2023-07-19 Tdk株式会社 被検物質の分析キット、及び被検物質の分析方法
EP3851855A1 (en) 2020-01-17 2021-07-21 Technische Universität München Sensing of molecules by electrochemical detection of nanoparticles

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5096669A (en) 1988-09-15 1992-03-17 I-Stat Corporation Disposable sensing device for real time fluid analysis
GB9318677D0 (en) * 1993-09-09 1993-10-27 Kodak Ltd Method and apparatus for measuring silver ion activity
US6071394A (en) 1996-09-06 2000-06-06 Nanogen, Inc. Channel-less separation of bioparticles on a bioelectronic chip by dielectrophoresis
US6143247A (en) 1996-12-20 2000-11-07 Gamera Bioscience Inc. Affinity binding-based system for detecting particulates in a fluid
US20010055812A1 (en) 1995-12-05 2001-12-27 Alec Mian Devices and method for using centripetal acceleration to drive fluid movement in a microfluidics system with on-board informatics
US6709869B2 (en) 1995-12-18 2004-03-23 Tecan Trading Ag Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system
US5863502A (en) 1996-01-24 1999-01-26 Sarnoff Corporation Parallel reaction cassette and associated devices
WO1998053301A2 (en) 1997-05-23 1998-11-26 Becton Dickinson And Company Automated microbiological testing apparatus and methods therefor
US6300138B1 (en) 1997-08-01 2001-10-09 Qualigen, Inc. Methods for conducting tests
CA2320296A1 (en) 1998-05-18 1999-11-25 University Of Washington Liquid analysis cartridge
IL126776A (en) * 1998-10-27 2001-04-30 Technion Res & Dev Foundation A method of investing gold
WO2000052457A1 (en) 1999-03-02 2000-09-08 Helix Biopharma Corporation Card-based biosensor device
US7041206B2 (en) 2000-03-09 2006-05-09 Clinical Analysis Corporation Medical diagnostic system
US8518328B2 (en) 2005-12-27 2013-08-27 Honeywell International Inc. Fluid sensing and control in a fluidic analyzer
FR2810739B1 (fr) 2000-06-26 2007-01-26 Centre Nat Rech Scient Immunodosage electrochimiques a l'aide de marqueurs metalliques colloidaux
US20040248093A1 (en) 2000-11-27 2004-12-09 Coombs James Howard Magneto-optical bio-discs and systems including related methods
WO2004016160A2 (en) 2002-08-19 2004-02-26 Iowa State University Research Foundation, Inc. Redox polymer nanoparticles
US7838296B2 (en) 2002-08-28 2010-11-23 Separation Technology, Inc. Methods and apparatus for ultrasonic determination of red blood cell indices
US20040058457A1 (en) 2002-08-29 2004-03-25 Xueying Huang Functionalized nanoparticles
US20040259076A1 (en) 2003-06-23 2004-12-23 Accella Scientific, Inc. Nano and micro-technology virus detection method and device
US7208784B2 (en) 2003-10-07 2007-04-24 Quantum Logic Devices, Inc. Single-electron transistor for detecting biomolecules
US8158062B2 (en) 2003-11-05 2012-04-17 Chris Dykes Disposable fluid sample collection device
US8617907B2 (en) * 2004-06-07 2013-12-31 Alere Switzerland Gmbh Determining the presence or amount of a metal-labelled species
US20060000710A1 (en) 2004-06-30 2006-01-05 Klaus Peter Weidenhaupt Fluid handling methods
WO2006065762A2 (en) 2004-12-13 2006-06-22 University Of South Carolina Surface enhanced raman spectroscopy using shaped gold nanoparticles
WO2006118420A1 (en) 2005-04-30 2006-11-09 Jae Chern Yoo Bio-disc, bio-driver apparatus, and assay method using the same
US20060263818A1 (en) 2005-05-23 2006-11-23 Axel Scherer High throughput multi-antigen microfluidic fluorescence immunoassays
US20060270049A1 (en) 2005-05-25 2006-11-30 Board Of Supervisors Of Louisiana State University & A & M College Enhanced detection of analytes on surfaces using gold nanoparticles
AU2007265628B2 (en) 2006-06-23 2012-12-06 Revvity Health Sciences, Inc. Methods and devices for microfluidic point-of-care immunoassays
CA2580589C (en) 2006-12-19 2016-08-09 Fio Corporation Microfluidic detection system
KR101153748B1 (ko) 2008-05-07 2012-06-14 재단법인서울대학교산학협력재단 바이오센서로 유용한 새로운 형태의 금／은 코어쉘 복합체
US8372435B2 (en) 2008-06-23 2013-02-12 Princeton University Modular monolayer coatings for selective attachment of nanoparticles to biomolecules

Also Published As

Publication number Publication date
US20100320092A1 (en) 2010-12-23
WO2009068862A1 (en) 2009-06-04
JP2011504593A (ja) 2011-02-10
EP2220494B1 (en) 2011-11-09
CN101971029A (zh) 2011-02-09
GB2458420A8 (en) 2009-10-07
GB2458420A (en) 2009-09-23
AU2008328588A1 (en) 2009-06-04
WO2009068862A8 (en) 2009-10-22
US8337692B2 (en) 2012-12-25
GB0912670D0 (en) 2009-08-26
EP2220494A1 (en) 2010-08-25
JP5055433B2 (ja) 2012-10-24
GB2458420B (en) 2009-10-28
CN101971029B (zh) 2013-08-07
NZ585851A (en) 2011-04-29
ATE533054T1 (de) 2011-11-15

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PC Assignment registered

Owner name: SERCO HOLDINGS LIMITED

Free format text: FORMER OWNER WAS: THE SECRETARY OF STATE FOR INNOVATION, UNIVERSITIES AND SKILLS OF HER MAJESTY'S BRITANNIC GOVERNMENT

PC Assignment registered

Owner name: AGPLUS DIAGNOSTICS LIMITED

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MK14 Patent ceased section 143(a) (annual fees not paid) or expired