AU2008274893A1

AU2008274893A1 - Synergistic mixture

Info

Publication number: AU2008274893A1
Application number: AU2008274893A
Authority: AU
Inventors: Antoinette Foster
Original assignee: PROSPORTS NUTRITION Pty Ltd
Current assignee: PROSPORTS NUTRITION Pty Ltd
Priority date: 2007-07-10
Filing date: 2008-07-10
Publication date: 2009-01-15
Also published as: WO2009006686A1

Description

WO 2009/006686 PCT/AU2008/001003 1 SYNERGISTIC MIXTURE Technical Area This invention relates to a synergistic mixture and, in particular, to one which can promote the feeling of wellness in the person who takes the mixture and can assist in generally maintaining various bodily functions. Background to the Invention There have been, over the centuries, various tonics which, at their time of adoption were believed to be beneficial to the user, either against specific symptoms, or generally. Most of these have, over the years, been proved to have little or no positive effect and some, at least, were effectively poisons. Outline of the Invention It is the object of this invention to provide a synergistic mixture which is beneficial to users, tends to promote a feeling of wellness, and is certainly non toxic, when taken in normal doses. The invention includes a synergistic mixture which incorporates one or more of vitamins, amino acids, minerals and herbal preparations. The mixture may include L-Glutathione.

WO 2009/006686 PCT/AU2008/001003 2 Description of an Embodiment of the Invention In order that the invention may be more readily understood we shall describe one particular embodiment of the invention. The vitamins (s) which are used in the mixture can be selected from the group comprising Vitamin A Vitamin E The amino acids from a group comprising L-Glutathione L-Proline The minerals from the group comprising Calcium salts Iron salts Zinc salts Magnesium salts The herbal preparations from the group Calendula Officialis. The preferred amino acid is L-Glutathione which is a tri-peptide, a protein comprised of one amino acid of Glutamic acid, Cysteine and Glycine. Glutathione is found and manufactured in every cell in the body but is found in highest concentrations in the heart muscle tissue and the liver. Glutathione is critical for healthy immune system function.

WO 2009/006686 PCT/AU2008/001003 3 Glutathione helps the body fight almost any disease, because it is a powerful antioxidant that helps maintain cellular health and helps prevent oxidative stress. Glutathione has been heavily researched, and the findings on this substance have been nothing short of amazing. Aside from being a powerful antioxidant booster and system detoxifier, glutathione helps produce, protect and repair deoxyribonucleic acid - DNA. In this protective role, glutathione boosts the immune system, thereby helping to power immune response and preventing the growth of cancerous cells. Thus, glutathione levels are correlated with aging and physical function. The only way to drastically increase glutathione levels, aside from consuming glutathione precursors, is through the ingestion of ascorbic acid - vitamin C. Boosting glutathione levels has been shown to boost sperm count in infertile men and non-weight training subjects saw increases in muscle mass by supplementing with glutathione, even without weight training. Gluththione is essential for immune system function and muscle growth, and any athlete who is glutathione deficient will suffer from decreased performance and a lack of muscle growth. Declines in glutathione levels are associated with ageing, and studies have shown that adults who took glutathione had better health than those who did not. Deficiencies of glutathione do not produce diseases, but low glutathione levels can accelerate ageing, can lead to functional decline and weaken the immune system. There have been a large number of papers which refer to the action of Glutathione.. The preferred Vitamins are Vitamins A and E.

WO 2009/006686 PCT/AU2008/001003 4 A further preferred amino acid is L-Proline. This is not an essential amino acid but may be synthesized by the body. It is one of the main components of collagen, the connective tissue structure that binds and supports all other tissues. Pauling 1 points out that there is evidence that vitamin C is required for conversion of prolyl residues or procollagen (the precursor of collagen) into the form that gives collagen its characteristic properties. The use of wound healing , and in the promotion of improved collagen status, as well as in cosmetic improvement of 'ageing' tissues has been proposed by researchers in California. Hydroxyproline, which the body incorporates into collagen, is readily transformed by the body from proline; it is incorporated into the structure of tendons and ligaments. Proline is one of the aromatic amino acids such as phenylalanine and tryptophan. Supplementation would seem to be indicated in cases of persistent soft tissues strains; hypermobile joints; soft tissue healing requirement, and in lax and 'sagging' tissues associated with ageing. Combined with Vitamin C supplementation is more effective. Pfeiffer states clearly that the protein collagen is neither properly formed, not maintained, if vitamin C is lacking. References : 1. Pauling, Linus, Vitamin C-The Common Cold and Flu, Freeman and Co 1976 2. Levine, Stephen, Allergy Research Group Pamphlet Concord, California 3. Anthony Harris, Your Body Futura 1979 4. Pfeiffer, Carl Mental and Elemental Nutrients, Keats 1975. Vitamin A is part of a larger team of antioxidant nutrients known as the carotenoids, which are the yellow and orange pigments found in fruits and vegetables. Since beta carotene converts in the body into vitamin A, it is often referred to a pro-vitamin A. However, being a tremendous immune system booster and a powerful antioxidant, WO 2009/006686 PCT/AU2008/001003 5 beta-carotene provides many additional benefits. The antioxidant effect plays a very important role in the prevention of heart disease. A study of 333 patients who took 50 mg of beta-carotene showed that the nutrient reduced major cardiovascular events by 50% in comparison with people who did not take the supplement. Beta-carotene was also found to have a protective effect in angina patients, who experienced far less chest pain on diets that were high in natural beta-carotene. Beta carotene is also known.to increase the level of protective HDL cholesterol. Vitamin E is a generic term for a group of related compounds called tocopherols occurring in four forms of which 'alpha' is the most potent. Found in only a few foods that are typically high in fat, supplementation becomes important especially in low fat diets. One of the vitamins basic functions is to protect cell membranes and help the body to use selenium and vitamin K. The staggering superiority of vitamin E therapy over the most concerted drug efforts was most convincingly demonstrated by conventional medicine, based on the findings of two Harvard studies: one of 40,000 male doctors, the other with more than 100,000 female nurses. The more vitamin E consumed, the lower the rate of cardiovascular disease. It is an excellent antioxidant shield, which prevents LDL cholesterol from sticking to the artery walls and at the same time, reduces the amount of the LDL cholesterol in the blood. At the same time, vitamin E increases the amount of the artery-cleansing HDL cholesterol and works to eliminate triglycerides (another dangerous blood fat). It lowers insulin and spares the heart from damage caused by a magnesium deficiency or a lack of oxygen, thus improving the biochemical changes caused by stress in patients suffering congestive heart failure. A preferred herb is Calendula Officinalis, which is a well known skin herb, is a main nutrient of the mixture. A particular mixture which we have found to be particularly efficacious has the WO 2009/006686 PCT/AU2008/001003 6 constituents as follows: L-Glutathione L-Proline Calendula Officinalis Calcium Ascorbate Iron Phosphate Vitamin A Vitamin E Calcium Phosphate Zinc Sulphate Magnesium Phosphate Seleno-Methionine. For the best results we believe that the user should take about 500 mg Once or twice a day. The mixtures of the invention have a very powerful synergistic detoxifying effect on the body generally. The glutathione help protect the body from oxidative stress and as oxidative stress is associated with aging it is believed that the mixture will have a general benefit both immediately and in the future. A preferred particular specific formulation of the product is: WO 2009/006686 PCT/AU2008/001003 7 RawMateial Name Ir put Selenomethionine 0.13 Equiv. Selenium I-Glutathione 120.00 Calcium Ascorbate Dihydrate 40.00 Equiv. Ascorbic Acid Equiv. Calcium Magesium Phosphate 12.50 Equiv. Magnesium Proline* 12.50 Retinyl acetate (Dry Vit A Acetate 500) 4.00 Equiv. Vitamin A Iron Phospbate Octahydrate 1.00 Equiv. Iron N Acetyl L Cysteine 12.50 Tn Calcium Phosphate 13.50 Equiv. Calcium Zinc Sulphate Heptahydrate 5.00 Equiv. Zinc Calendula otfcinaW Fower Powder Extract 5.56 Dy con. 4.531 60% Emnolm Equiv. Calendula officinalis flower Biocell Collagen 11* 50.00 Lycopersicon esculenrm (Tomato) herb ext. &yco. 20: inow 10%HEthy c./1In% 75.00 Ed.no .bsolu STD 6% lycope Equiv. Lycopersicon esculentum herb Equiv. Lycopene Matricaria recutita flower powder extract conc. 4:1 ih 70% Edn 3.13 Equiv. Matricana recutita flower Camellia sinensis leaf standardised dry powdr extac con.. 12:1 wih t00% Watr low% Hh<. :..s to wv 4.17 85% PoIyph nd., 40% EGGG .nd 60% Equiv. Camelliasinensis leaf Equiv. Polyphenols Equiv. EGGG Equiv. Catechins Colloidal Silica Hydrous 10.43 Equiv. Silica Soy Bean Extract 50.00 Capsule Shell Vegi-Cap 118.00 Total 679.40 WO 2009/006686 PCT/AU2008/001003 8 Whilst there has been herein described certain embodiments of the invention, it is to be understood that the elements of the mixture, and their proportions can be varied as required for different applications and at different times and all such variations are deemed to be within the scope of the invention.

Claims

1. A synergistic mixture which incorporates one or more of vitamins, amino acids, minerals and herbal preparations.

2. A synergistic mixture as claimed in claim wherein the vitamins (s) which are used in the mixture are selected from the groups comprising Vitamin-A and Vitamin E.

3. A synergistic mixture as claimed in claim 1 or claim 2 wherein the amino acids are selected from a group comprising L-Glutathione and L-Proline.

4. A synergistic mixture as claimed in claim 1 or claim 2 wherein the amino acid is L-Glutathione.

5. A synergistic mixture as claimed in any one of claims 1 to 4 wherein the minerals are selected from the group comprising calcium salts, iron salts, zinc salts and magnesium salts.

6. A synergistic mixture as claimed in any preceding claim wherein the herbal preparation includes Calendula Officialis

7. A synergistic mixture as claimed In any preceding calm wherein the mixture includes: L-Glutathione L-Proline Calendula Officinalis Calcium Ascorbate Iron Phosphate Vitamin A WO 2009/006686 PCT/AU2008/001003 10 Vitamin E Calcium Phosphate Zinc Sulphate Magnesium Phosphate Seleno-Methionine

8. A synergistic mixture as claimed in any preceding claim and as described in relation to the specific formulation set out herein.

9. A synergistic mixture substantially as hereinbefore described.