AU2007336121B2 - Oral health composition comprising Alchemilla vulgaris - Google Patents
Oral health composition comprising Alchemilla vulgaris Download PDFInfo
- Publication number
- AU2007336121B2 AU2007336121B2 AU2007336121A AU2007336121A AU2007336121B2 AU 2007336121 B2 AU2007336121 B2 AU 2007336121B2 AU 2007336121 A AU2007336121 A AU 2007336121A AU 2007336121 A AU2007336121 A AU 2007336121A AU 2007336121 B2 AU2007336121 B2 AU 2007336121B2
- Authority
- AU
- Australia
- Prior art keywords
- composition
- alchemilla vulgaris
- animal
- vulgaris
- plaque
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 235000000008 Alchemilla vulgaris Nutrition 0.000 title claims description 70
- 239000000203 mixture Substances 0.000 title claims description 68
- 241001408845 Alchemilla xanthochlora Species 0.000 title claims 12
- 230000036541 health Effects 0.000 title description 43
- 241001465754 Metazoa Species 0.000 claims description 76
- 208000002064 Dental Plaque Diseases 0.000 claims description 33
- 241000282326 Felis catus Species 0.000 claims description 21
- 230000001580 bacterial effect Effects 0.000 claims description 20
- 208000007565 gingivitis Diseases 0.000 claims description 18
- 238000000034 method Methods 0.000 claims description 17
- 108091005804 Peptidases Proteins 0.000 claims description 16
- 239000004365 Protease Substances 0.000 claims description 16
- 244000052616 bacterial pathogen Species 0.000 claims description 10
- 238000004519 manufacturing process Methods 0.000 claims description 10
- 210000000214 mouth Anatomy 0.000 claims description 10
- 230000000485 pigmenting effect Effects 0.000 claims description 8
- 102000035195 Peptidases Human genes 0.000 claims description 5
- 241000191992 Peptostreptococcus Species 0.000 claims description 5
- 230000002757 inflammatory effect Effects 0.000 claims description 3
- 244000082872 Alchemilla vulgaris Species 0.000 description 58
- 238000003556 assay Methods 0.000 description 23
- 239000000047 product Substances 0.000 description 19
- 241000282472 Canis lupus familiaris Species 0.000 description 16
- 241000894006 Bacteria Species 0.000 description 15
- 239000002028 Biomass Substances 0.000 description 14
- 230000009467 reduction Effects 0.000 description 14
- 230000000694 effects Effects 0.000 description 12
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 11
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 10
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 10
- 239000013589 supplement Substances 0.000 description 10
- 208000028169 periodontal disease Diseases 0.000 description 8
- 210000003296 saliva Anatomy 0.000 description 8
- 241000282324 Felis Species 0.000 description 7
- 235000005911 diet Nutrition 0.000 description 7
- 201000010099 disease Diseases 0.000 description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 7
- 239000000284 extract Substances 0.000 description 7
- 235000013305 food Nutrition 0.000 description 7
- 230000005764 inhibitory process Effects 0.000 description 7
- 239000007788 liquid Substances 0.000 description 7
- 230000002829 reductive effect Effects 0.000 description 7
- 230000037213 diet Effects 0.000 description 6
- 230000006872 improvement Effects 0.000 description 6
- 235000018102 proteins Nutrition 0.000 description 6
- 102000004169 proteins and genes Human genes 0.000 description 6
- 108090000623 proteins and genes Proteins 0.000 description 6
- 238000004458 analytical method Methods 0.000 description 5
- 230000015572 biosynthetic process Effects 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 5
- 230000002401 inhibitory effect Effects 0.000 description 5
- 239000002054 inoculum Substances 0.000 description 5
- 238000012423 maintenance Methods 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 4
- MJVAVZPDRWSRRC-UHFFFAOYSA-N Menadione Chemical compound C1=CC=C2C(=O)C(C)=CC(=O)C2=C1 MJVAVZPDRWSRRC-UHFFFAOYSA-N 0.000 description 4
- 229960003260 chlorhexidine Drugs 0.000 description 4
- 210000001315 dental pellicle Anatomy 0.000 description 4
- 238000011161 development Methods 0.000 description 4
- 239000000499 gel Substances 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 239000006072 paste Substances 0.000 description 4
- 230000007505 plaque formation Effects 0.000 description 4
- 230000002265 prevention Effects 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- 239000000120 Artificial Saliva Substances 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- 244000068988 Glycine max Species 0.000 description 3
- 235000010469 Glycine max Nutrition 0.000 description 3
- 244000269722 Thea sinensis Species 0.000 description 3
- 235000006468 Thea sinensis Nutrition 0.000 description 3
- 102000004142 Trypsin Human genes 0.000 description 3
- 108090000631 Trypsin Proteins 0.000 description 3
- 230000035508 accumulation Effects 0.000 description 3
- 238000009825 accumulation Methods 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 235000015111 chews Nutrition 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 239000013078 crystal Substances 0.000 description 3
- 230000035611 feeding Effects 0.000 description 3
- 238000011534 incubation Methods 0.000 description 3
- 235000013372 meat Nutrition 0.000 description 3
- 238000004806 packaging method and process Methods 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 238000011002 quantification Methods 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 239000012588 trypsin Substances 0.000 description 3
- 108010068370 Glutens Proteins 0.000 description 2
- 241000282412 Homo Species 0.000 description 2
- 241000684246 Peptostreptococcus stomatis Species 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- 240000008042 Zea mays Species 0.000 description 2
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 230000001055 chewing effect Effects 0.000 description 2
- 239000006781 columbia blood agar Substances 0.000 description 2
- 230000001627 detrimental effect Effects 0.000 description 2
- 235000021312 gluten Nutrition 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 238000011081 inoculation Methods 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 235000012054 meals Nutrition 0.000 description 2
- 239000000401 methanolic extract Substances 0.000 description 2
- 230000003239 periodontal effect Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- 230000004083 survival effect Effects 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 235000012711 vitamin K3 Nutrition 0.000 description 2
- 239000011652 vitamin K3 Substances 0.000 description 2
- 229940041603 vitamin k 3 Drugs 0.000 description 2
- 235000007319 Avena orientalis Nutrition 0.000 description 1
- 244000075850 Avena orientalis Species 0.000 description 1
- 241000606125 Bacteroides Species 0.000 description 1
- 241000282465 Canis Species 0.000 description 1
- 241000700199 Cavia porcellus Species 0.000 description 1
- 235000019750 Crude protein Nutrition 0.000 description 1
- 102000004127 Cytokines Human genes 0.000 description 1
- 108090000695 Cytokines Proteins 0.000 description 1
- 244000004281 Eucalyptus maculata Species 0.000 description 1
- 241000605986 Fusobacterium nucleatum Species 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- 206010018910 Haemolysis Diseases 0.000 description 1
- 108060003951 Immunoglobulin Proteins 0.000 description 1
- 238000012404 In vitro experiment Methods 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 102100027612 Kallikrein-11 Human genes 0.000 description 1
- 235000019687 Lamb Nutrition 0.000 description 1
- DEOKFPFLXFNAON-UHFFFAOYSA-N N-α-Benzoyl-DL-arginine 4-nitroanilide hydrochloride Chemical compound Cl.C=1C=C([N+]([O-])=O)C=CC=1NC(=O)C(CCCN=C(N)N)NC(=O)C1=CC=CC=C1 DEOKFPFLXFNAON-UHFFFAOYSA-N 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 241000192033 Peptostreptococcus sp. Species 0.000 description 1
- 208000005888 Periodontal Pocket Diseases 0.000 description 1
- 241000605894 Porphyromonas Species 0.000 description 1
- 241000605861 Prevotella Species 0.000 description 1
- 238000000692 Student's t-test Methods 0.000 description 1
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical class [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 1
- 208000008312 Tooth Loss Diseases 0.000 description 1
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 description 1
- 240000000359 Triticum dicoccon Species 0.000 description 1
- 101710152431 Trypsin-like protease Proteins 0.000 description 1
- 241000607122 Uncaria tomentosa Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 description 1
- 238000005299 abrasion Methods 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000010062 adhesion mechanism Effects 0.000 description 1
- 241001148470 aerobic bacillus Species 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 235000015278 beef Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000032770 biofilm formation Effects 0.000 description 1
- 235000015895 biscuits Nutrition 0.000 description 1
- 230000001680 brushing effect Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000011472 cat’s claw Nutrition 0.000 description 1
- 230000033383 cell-cell recognition Effects 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000002026 chloroform extract Substances 0.000 description 1
- 230000001332 colony forming effect Effects 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 230000002542 deteriorative effect Effects 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 235000013325 dietary fiber Nutrition 0.000 description 1
- 235000015872 dietary supplement Nutrition 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 230000009982 effect on human Effects 0.000 description 1
- 239000000469 ethanolic extract Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 208000024693 gingival disease Diseases 0.000 description 1
- 201000005562 gingival recession Diseases 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 244000005709 gut microbiome Species 0.000 description 1
- 230000007407 health benefit Effects 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- BTIJJDXEELBZFS-UHFFFAOYSA-K hemin Chemical compound [Cl-].[Fe+3].[N-]1C(C=C2C(=C(C)C(C=C3C(=C(C)C(=C4)[N-]3)C=C)=N2)C=C)=C(C)C(CCC(O)=O)=C1C=C1C(CCC(O)=O)=C(C)C4=N1 BTIJJDXEELBZFS-UHFFFAOYSA-K 0.000 description 1
- 229940025294 hemin Drugs 0.000 description 1
- BTIJJDXEELBZFS-QDUVMHSLSA-K hemin Chemical compound CC1=C(CCC(O)=O)C(C=C2C(CCC(O)=O)=C(C)\C(N2[Fe](Cl)N23)=C\4)=N\C1=C/C2=C(C)C(C=C)=C3\C=C/1C(C)=C(C=C)C/4=N\1 BTIJJDXEELBZFS-QDUVMHSLSA-K 0.000 description 1
- 230000008588 hemolysis Effects 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 102000018358 immunoglobulin Human genes 0.000 description 1
- 229940072221 immunoglobulins Drugs 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 230000000503 lectinlike effect Effects 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 235000009973 maize Nutrition 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 244000005706 microflora Species 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 239000002324 mouth wash Substances 0.000 description 1
- 229940051866 mouthwash Drugs 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 201000001245 periodontitis Diseases 0.000 description 1
- 230000007406 plaque accumulation Effects 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 239000013643 reference control Substances 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 235000009561 snack bars Nutrition 0.000 description 1
- 235000011888 snacks Nutrition 0.000 description 1
- 235000019832 sodium triphosphate Nutrition 0.000 description 1
- 238000007447 staining method Methods 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 238000012353 t test Methods 0.000 description 1
- 229940034610 toothpaste Drugs 0.000 description 1
- 239000000606 toothpaste Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 229960003500 triclosan Drugs 0.000 description 1
- 241001148471 unidentified anaerobic bacterium Species 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000036642 wellbeing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Birds (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
- Fodder In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0625429.6A GB0625429D0 (en) | 2006-12-20 | 2006-12-20 | Composition |
| GB0625429.6 | 2006-12-20 | ||
| PCT/GB2007/004522 WO2008074978A1 (en) | 2006-12-20 | 2007-11-27 | Oral health composition comprising alchemilla vulgaris |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2007336121A1 AU2007336121A1 (en) | 2008-06-26 |
| AU2007336121B2 true AU2007336121B2 (en) | 2014-03-06 |
Family
ID=37734533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2007336121A Ceased AU2007336121B2 (en) | 2006-12-20 | 2007-11-27 | Oral health composition comprising Alchemilla vulgaris |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20100061943A1 (enExample) |
| EP (1) | EP2099525A1 (enExample) |
| JP (1) | JP2010513431A (enExample) |
| AU (1) | AU2007336121B2 (enExample) |
| CA (1) | CA2672515A1 (enExample) |
| GB (1) | GB0625429D0 (enExample) |
| WO (1) | WO2008074978A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3022140B1 (fr) * | 2014-06-13 | 2016-06-03 | Laurent Haddad | Composition d'un dispositif medical ou produit cosmetique a base d'extrait de pepin de pamplemousse, d'extrait de feuille d'alchemille, d'extrait de stevia et de curcumine |
| JP2020167974A (ja) * | 2019-04-05 | 2020-10-15 | ライオン株式会社 | インビトロバイオフィルムモデル用菌体組成物及びその用途 |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2461499A1 (fr) * | 1979-07-23 | 1981-02-06 | Inverni Della Beffa Spa | Composition pharmaceutique a base d'extraits de myrtille |
| WO1993011676A1 (en) * | 1991-12-17 | 1993-06-24 | Leuven Dirk Hector Van | New tobacco substitutes |
| DE19712659C1 (de) * | 1997-03-26 | 1998-08-20 | Weber & Weber Gmbh | Verwendung eines Extraktes von Alchemilla vulgaris |
| WO1999034811A1 (en) * | 1998-01-05 | 1999-07-15 | Farmo-Nat Ltd. | Anti-fungal compositions with prolonged activity |
| WO2000074668A1 (fr) * | 1999-06-08 | 2000-12-14 | Ravi Shrivastava | Composition non solide pour application locale |
| WO2001015680A1 (en) * | 1999-09-01 | 2001-03-08 | Van Beek Global/Ninkov L.L.C. | Composition for treatment of infections of humans and animals |
| US7074391B1 (en) * | 2000-10-16 | 2006-07-11 | Biocosmetics, S.L. | Use of olive oil in the preparation of a product for oral hygiene for eliminating or reducing bacterial plaque and/or bacteria in the mouth |
| WO2008010188A2 (en) * | 2006-07-17 | 2008-01-24 | Ad-Med Biotechnology, Llc | Antimicrobial and pesticidal compositions and methods comprising reduced monoterpene oil extracted from myrtaceae |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1466578A (en) * | 1921-08-20 | 1923-08-28 | Clifton Isabel | Pyorrhea remedy |
| JP2001233778A (ja) * | 2000-02-22 | 2001-08-28 | Fuji Sangyo Kk | ５−リポキシゲナーゼ活性阻害剤及び５−リポキシゲナーゼ活性阻害成分含有抗アレルギー食品 |
| EP1560571A4 (en) * | 2002-11-14 | 2007-11-28 | Innozen Inc | EDIBLE FILM FOR THE RELIEF OF COUGH OR SYMPTOMS ASSOCIATED WITH PHARYNGITIS |
| JP4979181B2 (ja) * | 2003-01-31 | 2012-07-18 | 株式会社ヤクルト本社 | グリケーション阻害剤及びその利用 |
-
2006
- 2006-12-20 GB GBGB0625429.6A patent/GB0625429D0/en not_active Ceased
-
2007
- 2007-11-27 CA CA002672515A patent/CA2672515A1/en not_active Abandoned
- 2007-11-27 US US12/517,342 patent/US20100061943A1/en not_active Abandoned
- 2007-11-27 JP JP2009542181A patent/JP2010513431A/ja active Pending
- 2007-11-27 WO PCT/GB2007/004522 patent/WO2008074978A1/en not_active Ceased
- 2007-11-27 AU AU2007336121A patent/AU2007336121B2/en not_active Ceased
- 2007-11-27 EP EP07824716A patent/EP2099525A1/en not_active Withdrawn
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2461499A1 (fr) * | 1979-07-23 | 1981-02-06 | Inverni Della Beffa Spa | Composition pharmaceutique a base d'extraits de myrtille |
| WO1993011676A1 (en) * | 1991-12-17 | 1993-06-24 | Leuven Dirk Hector Van | New tobacco substitutes |
| DE19712659C1 (de) * | 1997-03-26 | 1998-08-20 | Weber & Weber Gmbh | Verwendung eines Extraktes von Alchemilla vulgaris |
| WO1999034811A1 (en) * | 1998-01-05 | 1999-07-15 | Farmo-Nat Ltd. | Anti-fungal compositions with prolonged activity |
| WO2000074668A1 (fr) * | 1999-06-08 | 2000-12-14 | Ravi Shrivastava | Composition non solide pour application locale |
| WO2001015680A1 (en) * | 1999-09-01 | 2001-03-08 | Van Beek Global/Ninkov L.L.C. | Composition for treatment of infections of humans and animals |
| US7074391B1 (en) * | 2000-10-16 | 2006-07-11 | Biocosmetics, S.L. | Use of olive oil in the preparation of a product for oral hygiene for eliminating or reducing bacterial plaque and/or bacteria in the mouth |
| WO2008010188A2 (en) * | 2006-07-17 | 2008-01-24 | Ad-Med Biotechnology, Llc | Antimicrobial and pesticidal compositions and methods comprising reduced monoterpene oil extracted from myrtaceae |
Non-Patent Citations (1)
| Title |
|---|
| Shrivastava, R. et al. "Treatment of Aphthous Stomatitis with Topical Alchemilla vulgaris in Glycerine" Clinical Drug Investigation (Oct. 2006) Vol.26 No.10 pages 567 to 573 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007336121A1 (en) | 2008-06-26 |
| US20100061943A1 (en) | 2010-03-11 |
| JP2010513431A (ja) | 2010-04-30 |
| WO2008074978A1 (en) | 2008-06-26 |
| EP2099525A1 (en) | 2009-09-16 |
| CA2672515A1 (en) | 2008-06-26 |
| GB0625429D0 (en) | 2007-01-31 |
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