AU2006207181A1 - HIV-1 gp41 fusion peptides for immunomodulation - Google Patents

HIV-1 gp41 fusion peptides for immunomodulation Download PDF

Info

Publication number
AU2006207181A1
AU2006207181A1 AU2006207181A AU2006207181A AU2006207181A1 AU 2006207181 A1 AU2006207181 A1 AU 2006207181A1 AU 2006207181 A AU2006207181 A AU 2006207181A AU 2006207181 A AU2006207181 A AU 2006207181A AU 2006207181 A1 AU2006207181 A1 AU 2006207181A1
Authority
AU
Australia
Prior art keywords
amino acid
peptide
seq
sequence
acid residues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2006207181A
Other languages
English (en)
Inventor
Irun R. Cohen
Doron Gerber
Francisco J. Quintana
Yechiel Shai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
Original Assignee
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Research and Development Co Ltd filed Critical Yeda Research and Development Co Ltd
Publication of AU2006207181A1 publication Critical patent/AU2006207181A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2006207181A 2005-01-24 2006-01-24 HIV-1 gp41 fusion peptides for immunomodulation Abandoned AU2006207181A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64560505P 2005-01-24 2005-01-24
US60/645,605 2005-01-24
PCT/IL2006/000096 WO2006077601A2 (en) 2005-01-24 2006-01-24 HIV-1 gp41 FUSION PEPTIDES FOR IMMUNOMODULATION

Publications (1)

Publication Number Publication Date
AU2006207181A1 true AU2006207181A1 (en) 2006-07-27

Family

ID=36692632

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006207181A Abandoned AU2006207181A1 (en) 2005-01-24 2006-01-24 HIV-1 gp41 fusion peptides for immunomodulation

Country Status (7)

Country Link
US (1) US20090270312A1 (enExample)
EP (1) EP1843777A2 (enExample)
JP (1) JP2008528480A (enExample)
CN (1) CN101115498A (enExample)
AU (1) AU2006207181A1 (enExample)
CA (1) CA2595414A1 (enExample)
WO (1) WO2006077601A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10138276B2 (en) 2009-09-30 2018-11-27 Signablok, Inc. Inhibition of TCR signaling with peptide variants
US8986712B2 (en) 2009-11-29 2015-03-24 Yeda Research And Development Co., Ltd. Peptides derived from HIV-1 gp41 transmembrane domain for t-immunomodulation
CN103732238A (zh) * 2011-06-08 2014-04-16 奥瑞基尼探索技术有限公司 用于免疫调节的治疗性化合物
EP2866820A1 (en) * 2012-06-27 2015-05-06 Yeda Research and Development Co. Ltd. Peptides derived from hiv gp41 for treating t-cell mediated pathologies
KR20170080579A (ko) 2014-10-01 2017-07-10 플랜트 헬스 케어, 인코포레이티드 파괴된 과민성 반응 박스를 갖는 유발제 펩티드 및 그의 용도
US10856546B2 (en) 2014-10-01 2020-12-08 Plant Health Care, Inc. Hypersensitive response elicitor peptides and use thereof
BR112018069945A2 (pt) 2016-04-06 2019-02-05 Plant Health Care Inc micróbios benéficos para distribuição de peptídeos ou proteínas efetoras e uso dos mesmos
MX389549B (es) 2016-04-06 2025-03-20 Plant Health Care Inc Peptidos derivados de inductores de respuesta de hipersensibilidad y su uso.
WO2018037416A1 (en) * 2016-08-25 2018-03-01 Yeda Research And Development Co. Ltd. Methods and compositions for treating autoimmune diseases
WO2018067582A2 (en) * 2016-10-03 2018-04-12 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Hiv-1 env fusion peptide immunogens and their use
KR20200049594A (ko) * 2018-10-24 2020-05-08 주식회사 툴젠 조작된 면역 세포

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5230887A (en) * 1990-07-11 1993-07-27 Immune Network Research Ltd. Immune system stabilizers for prevention and therapy of disorders associated with immune system disfunction
US5444044A (en) * 1992-03-26 1995-08-22 New York Blood Center Synthetic polypeptides as inhibitors of HIV-1
US6479055B1 (en) * 1993-06-07 2002-11-12 Trimeris, Inc. Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission
US5464933A (en) * 1993-06-07 1995-11-07 Duke University Synthetic peptide inhibitors of HIV transmission
US6316420B1 (en) * 1998-07-28 2001-11-13 Technion Research And Development Foundation Ltd. DNA cytokine vaccines and use of same for protective immunity against multiple sclerosis
ATE294859T1 (de) * 1999-09-17 2005-05-15 Univ Keio Polypeptid, humanin, welches das absterben von nervenzellen hemmt
DE19957838C2 (de) * 1999-11-25 2002-11-21 Pette Heinrich Inst Gentherapie von HIV-Infizierten durch Expression von Membran-verankerten gp41-Peptiden
WO2004103312A2 (en) * 2003-05-19 2004-12-02 Progenics Pharmaceuticals, Inc. Peptides useful as hiv fusion inhibitors

Also Published As

Publication number Publication date
JP2008528480A (ja) 2008-07-31
US20090270312A1 (en) 2009-10-29
WO2006077601A2 (en) 2006-07-27
CN101115498A (zh) 2008-01-30
CA2595414A1 (en) 2006-07-27
WO2006077601A3 (en) 2006-11-23
EP1843777A2 (en) 2007-10-17

Similar Documents

Publication Publication Date Title
DE69326064T2 (de) Peptide des menschlichen Proteins P53 zum Gebrauch in menschlichen-zytotoxischen-T-Zell-Antwort-induzierenden Kompositionen sowie menschliche P53-Protein-spezifische T-Lymphocyten
TWI341844B (en) Hiv fusion inhibitor peptides with improved biological properties
Quintana et al. HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation
JP2012115277A (ja) ウイルス感染の治療
CN100482685C (zh) 来源于髓鞘碱性蛋白的耐受原性肽
US20090270312A1 (en) Hiv-i gp41 fusion peptides for immunomodulaltion
RU2741123C1 (ru) Липопептид для эффективного ингибирования вич, его производное, фармацевтическая композиция и их применение
US6436903B1 (en) Immunomodulating compounds comprising d-isomers of amino acids
US8986712B2 (en) Peptides derived from HIV-1 gp41 transmembrane domain for t-immunomodulation
US20150175666A1 (en) Peptides derived from hiv gp41 for treating t-cell mediated pathologies
JP2007536910A (ja) ウイルス感染の治療
EP0960886B1 (en) Peptide T and related peptides in the treatment of inflammation, including multiple sclerosis
US7323174B1 (en) Modulation of immune response and methods based thereon
Rees et al. The effect of lipoylation on CD4 T-cell recognition of the 19,000 MW Mycobacterium tuberculosis antigen
Estaquier et al. T helper cell epitopes of the human immunodeficiency virus (HIV-1) nef protein in rats and chimpanzees
WO2007068163A1 (en) Hiv fusion inhibitor peptides and use thereof
JP7778696B2 (ja) S-アレスチンペプチドを含む組成物
WO1997044351A1 (en) Immunomodulating dimers
US7011834B1 (en) Immunomodulating dimers
US20090214583A1 (en) Epitope-enhancement of a human cd4 hiv epitope
JP2023538002A (ja) 制御性t細胞エピトープ
JP2023520989A (ja) 1型糖尿病の予防および治療に有用なtレジトープ構築物
WO2005097180A1 (fr) Antigene tat dimerique et ses applications pour la vaccination anti-vih.
JPH09504273A (ja) Hivに対して使用するための多分岐ペプチド構築物
JPWO2021195508A5 (enExample)

Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period