AU2006206738A1 - Mitotic kinesin inhibitors - Google Patents
Mitotic kinesin inhibitors Download PDFInfo
- Publication number
- AU2006206738A1 AU2006206738A1 AU2006206738A AU2006206738A AU2006206738A1 AU 2006206738 A1 AU2006206738 A1 AU 2006206738A1 AU 2006206738 A AU2006206738 A AU 2006206738A AU 2006206738 A AU2006206738 A AU 2006206738A AU 2006206738 A1 AU2006206738 A1 AU 2006206738A1
- Authority
- AU
- Australia
- Prior art keywords
- alkyl
- cycloalkyl
- aryl
- heterocyclyl
- ros
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64493305P | 2005-01-19 | 2005-01-19 | |
| US60/644,933 | 2005-01-19 | ||
| PCT/US2006/001364 WO2006078574A2 (en) | 2005-01-19 | 2006-01-13 | Mitotic kinesin inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2006206738A1 true AU2006206738A1 (en) | 2006-07-27 |
Family
ID=36692758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2006206738A Abandoned AU2006206738A1 (en) | 2005-01-19 | 2006-01-13 | Mitotic kinesin inhibitors |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20080102068A1 (https=) |
| EP (1) | EP1856128A4 (https=) |
| JP (1) | JP4545196B2 (https=) |
| CN (1) | CN101107253A (https=) |
| AU (1) | AU2006206738A1 (https=) |
| CA (1) | CA2595127A1 (https=) |
| WO (1) | WO2006078574A2 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GT200600371A (es) * | 2005-08-17 | 2007-03-21 | Formas de dosis sólidas de valsartan y amlodipina y método para hacer las mismas | |
| WO2009001214A2 (en) * | 2007-06-28 | 2008-12-31 | Pfizer Products Inc. | Thieno[2,3-d]pyrimidin-4(3h)-one, isoxazolo[5,4-d]pyrimidin-4(5h)-one and isothiazolo[5,4-d]pyrimidin-4(5h)-one derivatives as calcium receptor antagonists |
| WO2009062199A1 (en) * | 2007-11-09 | 2009-05-14 | Fox Chase Cancer Center | EGFR/NEDD9/TGF-β LNTERACTOME AND METHODS OF USE THEREOF FOR THE IDENTIFICATION OF AGENTS HAVING EFFICACY IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS |
| US20130331294A1 (en) | 2007-11-09 | 2013-12-12 | Fox Chase Cancer Center | Egfr/nedd9/tgf-beta interactome and methods of use thereof for the identification of agents having efficacy in the treatment of hyperproliferative disorders |
| SG183304A1 (en) | 2010-02-17 | 2012-09-27 | Takeda Pharmaceutical | Heterocyclic compound |
| WO2011128388A2 (en) * | 2010-04-15 | 2011-10-20 | Novartis Ag | Oxazole and thiazole compounds as ksp inhibitors |
| EA201201404A1 (ru) * | 2010-04-15 | 2013-04-30 | Новартис Аг | Триазолы как ингибиторы кбв (кинезин-белок веретена) |
| EP3512857B1 (en) | 2016-09-14 | 2021-02-24 | Janssen Pharmaceutica NV | Spiro bicyclic inhibitors of menin-mll interaction |
| CA3033020A1 (en) * | 2016-09-14 | 2018-03-22 | Janssen Pharmaceutica Nv | Fused bicyclic inhibitors of menin-mll interaction |
| US12084462B2 (en) | 2016-09-14 | 2024-09-10 | Janssen Pharmaceutica Nv | Spiro bicyclic inhibitors of menin-MLL interaction |
| CN110248946B (zh) | 2016-12-15 | 2023-05-23 | 詹森药业有限公司 | Menin-MLL相互作用的氮杂环庚烷抑制剂 |
| US11396517B1 (en) | 2017-12-20 | 2022-07-26 | Janssen Pharmaceutica Nv | Exo-aza spiro inhibitors of menin-MLL interaction |
| EP4076466B1 (en) * | 2019-12-18 | 2026-03-11 | Universite De Montreal | Modulators of cullin 3 adaptor kbtbd4 as anti-cancer compounds |
| TW202525813A (zh) | 2019-12-19 | 2025-07-01 | 比利時商健生藥品公司 | 經取代之直鏈螺環接衍生物 |
| TW202508595A (zh) | 2023-05-04 | 2025-03-01 | 美商銳新醫藥公司 | 用於ｒａｓ相關疾病或病症之組合療法 |
| US20250049810A1 (en) | 2023-08-07 | 2025-02-13 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| AU2024360465A1 (en) | 2023-10-12 | 2026-04-09 | Revolution Medicines, Inc. | Macrocyclic ras inhibitors |
| WO2025171296A1 (en) | 2024-02-09 | 2025-08-14 | Revolution Medicines, Inc. | Ras inhibitors |
| TW202547461A (zh) | 2024-05-17 | 2025-12-16 | 美商銳新醫藥公司 | Ｒａｓ抑制劑 |
| WO2025255438A1 (en) | 2024-06-07 | 2025-12-11 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2025265060A1 (en) | 2024-06-21 | 2025-12-26 | Revolution Medicines, Inc. | Therapeutic compositions and methods for managing treatment-related effects |
| WO2026006747A1 (en) | 2024-06-28 | 2026-01-02 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026015801A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015796A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015790A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015825A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Use of ras inhibitor for treating pancreatic cancer |
| WO2026050446A1 (en) | 2024-08-29 | 2026-03-05 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026072904A2 (en) | 2024-09-26 | 2026-04-02 | Revolution Medicines, Inc. | Compositions and methods for treating lung cancer |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ20021428A3 (cs) * | 1999-10-27 | 2002-11-13 | Cytokinetics, Inc. | Způsoby a kompozice vyuľívající chinazoliny |
| JP2005515208A (ja) * | 2001-12-06 | 2005-05-26 | メルク エンド カムパニー インコーポレーテッド | 有糸分裂性キネシン阻害剤 |
| CA2468156A1 (en) * | 2001-12-06 | 2003-06-19 | Merck & Co., Inc. | Azolopyrimidinone compounds and their use |
| US20050107404A1 (en) * | 2001-12-06 | 2005-05-19 | Fraley Mark E. | Mitotic kinesin inhibitors |
| CA2467722A1 (en) * | 2001-12-06 | 2003-06-19 | Merck & Co., Inc. | Thienopyrimidinone derivatives as mitotic kinesin inhibitors |
| AU2003247891A1 (en) * | 2002-07-08 | 2004-01-23 | Merck & Co., Inc. | Mitotic kinesin binding site |
| WO2004064741A2 (en) * | 2003-01-17 | 2004-08-05 | Cytokinetics Inc. | Compounds, compositions, and methods |
| NZ542227A (en) * | 2003-03-07 | 2008-12-24 | Astrazeneca Ab | Novel fused heterocycles and uses thereof |
-
2006
- 2006-01-13 EP EP06718441A patent/EP1856128A4/en not_active Withdrawn
- 2006-01-13 WO PCT/US2006/001364 patent/WO2006078574A2/en not_active Ceased
- 2006-01-13 CA CA002595127A patent/CA2595127A1/en not_active Abandoned
- 2006-01-13 US US11/795,440 patent/US20080102068A1/en not_active Abandoned
- 2006-01-13 JP JP2007552192A patent/JP4545196B2/ja not_active Expired - Fee Related
- 2006-01-13 AU AU2006206738A patent/AU2006206738A1/en not_active Abandoned
- 2006-01-13 CN CNA2006800025407A patent/CN101107253A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006078574A3 (en) | 2007-03-22 |
| JP4545196B2 (ja) | 2010-09-15 |
| WO2006078574A2 (en) | 2006-07-27 |
| EP1856128A4 (en) | 2009-12-23 |
| JP2008527038A (ja) | 2008-07-24 |
| US20080102068A1 (en) | 2008-05-01 |
| EP1856128A2 (en) | 2007-11-21 |
| CN101107253A (zh) | 2008-01-16 |
| CA2595127A1 (en) | 2006-07-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2006206738A1 (en) | Mitotic kinesin inhibitors | |
| US7629373B2 (en) | Mitotic kinesin inhibitors | |
| AU2004305069C1 (en) | Mitotic kinesin inhibitors | |
| US20080045492A1 (en) | Mitotic Kinesin Inhibitors | |
| US7632839B2 (en) | Mitotic kinesin inhibitors | |
| EP1851213A2 (en) | Mitotic kinesin inhibitors | |
| US20090124641A1 (en) | Mitotic Kinesin Inhibitors | |
| EP1765830B1 (en) | Mitotic kinesin inhibitors | |
| EP1773326A2 (en) | Mitotic kinesin inhibitors | |
| US7732472B2 (en) | Mitotic kinesin inhibitors | |
| CA2547746A1 (en) | Mitotic kinesin inhibitors | |
| WO2006023083A1 (en) | Mitotic kinesin inhibitors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |