US2457405A
(en)
*
|
1945-09-25 |
1948-12-28 |
Monsanto Chemicals |
Halo nitroparaffin modified aminoplasts
|
US3261828A
(en)
*
|
1962-10-04 |
1966-07-19 |
Hoffmann La Roche |
3h-1,4-benzodiazepine-2,5(1h,4h)-dione compounds
|
US3415814A
(en)
*
|
1966-09-28 |
1968-12-10 |
Sterling Drug Inc |
4-(cyclopropylmethyl)-3h-1,4-benzodiazepine-2,5(1h,4h)-dione
|
US3384635A
(en)
*
|
1966-09-28 |
1968-05-21 |
Sterling Drug Inc |
1, 4-benzodiazepine derivatives
|
AT280290B
(de)
|
1967-11-24 |
1970-04-10 |
Boehringer Sohn Ingelheim |
Verfahren zur Herstellung von neuen 1-Phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dionen
|
USRE30293E
(en)
*
|
1969-03-18 |
1980-06-03 |
Knoll A.G. |
Process for preparing 1,5-benzodiazepine-2-ones
|
US4108852A
(en)
*
|
1969-03-18 |
1978-08-22 |
Knoll Ag. |
Process for preparing 1,5-benzodiazepine-2-ones
|
GB1324469A
(en)
*
|
1970-10-28 |
1973-07-25 |
Knoll Ag |
Derivatives of benzodiazepines
|
ZA7465B
(en)
*
|
1973-01-16 |
1974-11-27 |
J Voorhees |
Proliferating skin diseases with acyl derivatives of cyclic adenosine monophosphate
|
IE38931B1
(en)
*
|
1973-03-09 |
1978-07-05 |
Lipha |
Triazolobenzodiazepines
|
US4076823A
(en)
*
|
1977-08-18 |
1978-02-28 |
E. R. Squibb & Sons, Inc. |
Triazolo-2,4-benzodiazepines
|
US4495101A
(en)
*
|
1983-04-28 |
1985-01-22 |
American Home Products Corporation |
Antiinflammatory 5H-tetrazolo (5,1-c)(1,4)benzodiazepine derivatives
|
US4551480A
(en)
*
|
1983-06-21 |
1985-11-05 |
Stiefel Laboratories, Inc. |
Compositions for the treatment of psoriasis
|
US4894366A
(en)
*
|
1984-12-03 |
1990-01-16 |
Fujisawa Pharmaceutical Company, Ltd. |
Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
|
US4820834A
(en)
|
1984-06-26 |
1989-04-11 |
Merck & Co., Inc. |
Benzodiazepine analogs
|
FR2591596B1
(fr)
|
1985-12-13 |
1988-09-09 |
Roussel Uclaf |
Nouvelles 4h-triazolo(4,3-a)(1,4)benzodiazepines, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
|
GB8608080D0
(en)
*
|
1986-04-02 |
1986-05-08 |
Fujisawa Pharmaceutical Co |
Solid dispersion composition
|
US4946778A
(en)
*
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
US4751223A
(en)
*
|
1986-10-14 |
1988-06-14 |
Hoechst-Roussel Pharmaceuticals, Inc. |
Antiinflammatory and analgesic aminoalkyl tetracyclic benzodiazepines
|
US4898861A
(en)
*
|
1987-03-26 |
1990-02-06 |
Hoffmann-La Roche Inc. |
Method for inhibiting the proliferation of tumor cells
|
US4970207A
(en)
*
|
1988-07-07 |
1990-11-13 |
Fujisawa Pharmaceutical Company, Ltd. |
Benzodiazepine derivatives
|
SE8804074D0
(sv)
|
1988-11-10 |
1988-11-10 |
Pharmacia Ab |
Sensorenhet och dess anvaendning i biosensorsystem
|
WO1990013332A1
(en)
|
1989-05-11 |
1990-11-15 |
Cedars-Sinai Medical Center |
Stent with sustained drug delivery
|
US5258510A
(en)
*
|
1989-10-20 |
1993-11-02 |
Otsuka Pharma Co Ltd |
Benzoheterocyclic compounds
|
US5041438A
(en)
*
|
1989-10-30 |
1991-08-20 |
Hoffmann-La Roche Inc. |
Method for treating retroviral infections with benzodiazepine compounds
|
US5324726A
(en)
*
|
1989-12-18 |
1994-06-28 |
Merck & Co., Inc. |
Benzodiazepine analogs
|
CA2049973C
(en)
|
1990-02-28 |
2002-12-24 |
Rodney G. Wolff |
Intralumenal drug eluting prosthesis
|
US5217591A
(en)
|
1990-05-14 |
1993-06-08 |
Labintelligence, Inc. |
Gel electrophoresis sample applicator/retriever
|
ATE145208T1
(de)
*
|
1990-07-06 |
1996-11-15 |
Yoshitomi Pharmaceutical |
Kondensierte thiophenverbindungen und deren verwendung
|
GB9015879D0
(en)
|
1990-07-19 |
1990-09-05 |
Fujisawa Pharmaceutical Co |
Benzodiazepine derivatives
|
BR9200951A
(pt)
*
|
1991-03-21 |
1992-11-17 |
Hoffmann La Roche |
Compostos, processo para sua producao,preparacoes farmaceuticas e uso
|
EP0637308A1
(en)
*
|
1992-03-16 |
1995-02-08 |
MERCK SHARP & DOHME LTD. |
Benzodiazepine derivatives, compositions containing them and their use in therapy
|
US5599352A
(en)
*
|
1992-03-19 |
1997-02-04 |
Medtronic, Inc. |
Method of making a drug eluting stent
|
US5288514A
(en)
*
|
1992-09-14 |
1994-02-22 |
The Regents Of The University Of California |
Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
|
US6524832B1
(en)
|
1994-02-04 |
2003-02-25 |
Arch Development Corporation |
DNA damaging agents in combination with tyrosine kinase inhibitors
|
US5444092A
(en)
*
|
1994-07-20 |
1995-08-22 |
Collins; Jerry |
Method and composition for treating psoriasis
|
EP0804425A2
(en)
|
1994-07-29 |
1997-11-05 |
Fujisawa Pharmaceutical Co., Ltd. |
Benzodiazepine derivatives
|
CA2195973A1
(en)
|
1994-08-18 |
1996-02-29 |
David A. Claremon |
N-2,3-dihydro-1-(2-propyl)-2-oxo-5-phenyl-1h-1,4-benzodiazepines
|
US5618792A
(en)
*
|
1994-11-21 |
1997-04-08 |
Cortech, Inc. |
Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil elastase
|
WO2000066106A2
(en)
|
1999-04-30 |
2000-11-09 |
The Regents Of The University Of Michigan |
Use of benzodiazepines for treating autoimmune diseases induced by apoptosis
|
US5677282A
(en)
*
|
1995-06-07 |
1997-10-14 |
Proscript, Inc. |
Amino acid amides of 1,3,4-thiadiazoles as matrix metalloproteinase
|
US5962337A
(en)
|
1995-06-29 |
1999-10-05 |
Pharmacopeia, Inc. |
Combinatorial 1,4-benzodiazepin-2,5-dione library
|
RU2096044C1
(ru)
|
1995-07-19 |
1997-11-20 |
Малое предприятие "Ветта" |
Ветеринарный имплантируемый препарат для регулирования биологического ритма животных
|
US5776946A
(en)
*
|
1995-08-28 |
1998-07-07 |
Mcgeer; Patrick L. |
Peripheral benzodiazepine receptor ligands as antiinflammatory agents
|
US6004942A
(en)
*
|
1995-08-30 |
1999-12-21 |
The Regents Of The University Of California |
Methods for treating arthritis by administering an apoptosis regulator
|
US6579854B1
(en)
|
1996-08-14 |
2003-06-17 |
Vanderbilt University |
Diagnosis and management of infection caused by chlamydia
|
AU8062998A
(en)
|
1997-06-09 |
1998-12-30 |
Hoeffer Pharmacia Biotech, Inc. |
Device and method for applying power to gel electrophoresis modules
|
US6074859A
(en)
*
|
1997-07-08 |
2000-06-13 |
Kikkoman Corporation |
Mutant-type bioluminescent protein, and process for producing the mutant-type bioluminescent protein
|
US6080568A
(en)
*
|
1997-08-19 |
2000-06-27 |
Genencor International, Inc. |
Mutant α-amylase comprising modification at residues corresponding to A210, H405 and/or T412 in Bacillus licheniformis
|
NZ502362A
(en)
*
|
1997-10-08 |
2001-05-25 |
Isotechnika Inc |
Deuterated cyclosporine A derivatives and their use as immunomodulating agents
|
US6100254A
(en)
*
|
1997-10-10 |
2000-08-08 |
Board Of Regents, The University Of Texas System |
Inhibitors of protein tyrosine kinases
|
FR2772271B1
(fr)
*
|
1997-12-11 |
2000-09-01 |
Union Pharma Scient Appl |
Nouvelle association pharmaceutique a activite analgesique
|
US6206914B1
(en)
|
1998-04-30 |
2001-03-27 |
Medtronic, Inc. |
Implantable system with drug-eluting cells for on-demand local drug delivery
|
WO1999058117A1
(fr)
|
1998-05-13 |
1999-11-18 |
Sanofi-Synthelabo |
Utilisation de composes reduisant l'apoptose
|
FR2779963A1
(fr)
|
1998-06-22 |
1999-12-24 |
Centre Nat Rech Scient |
Utilisation d'un compose possedant une affinite pour le recepteur mitochondrial des benzodiazepines en therapie du cancer
|
HRP990246A2
(en)
*
|
1998-08-07 |
2000-06-30 |
Du Pont Pharm Co |
Succinoylamino benzodiazepines as inhibitors of a beta protein production
|
US6277844B1
(en)
*
|
1998-09-14 |
2001-08-21 |
Sydney Spector |
Compound for selective treatment of malignant cells by inhibiting cell cycle progression, decreasing Bcl2, and increasing apoptosis
|
US20030044776A1
(en)
*
|
1998-09-25 |
2003-03-06 |
James A. Dykens |
Compositions and methods for identifying agents that alter mitochondrial permeability transition pores
|
GB9823873D0
(en)
*
|
1998-10-30 |
1998-12-30 |
Pharmacia & Upjohn Spa |
2-ureido-thiazole derivatives,process for their preparation,and their use as antitumour agents
|
FR2785803B1
(fr)
|
1998-11-17 |
2005-03-25 |
Sanofi Sa |
Utilisation d'une substance se liant au recepteur peripherique des benzodiazepines dans le traitement des stress cutanes
|
US7175953B2
(en)
*
|
1999-04-09 |
2007-02-13 |
Institute Fuer Diagnostik Forschung |
Short-warp peptide-dye conjugate as contrast agent for optical diagnostic
|
US20030119029A1
(en)
*
|
1999-04-30 |
2003-06-26 |
Regents Of The University Of Michigan |
Compositions and methods relating to novel benzodiazepine compounds and targets thereof
|
US20060025388A1
(en)
|
1999-04-30 |
2006-02-02 |
Glick Gary D |
Compositions and methods relating to novel compounds and targets thereof
|
US7276348B2
(en)
|
1999-04-30 |
2007-10-02 |
Regents Of The University Of Michigan |
Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof
|
US20050113460A1
(en)
|
1999-04-30 |
2005-05-26 |
The Regents Of The University Of Michigan |
Compositions and methods relating to novel compounds and targets thereof
|
US20040176358A1
(en)
*
|
1999-04-30 |
2004-09-09 |
The Regents Of The University Of Michigan |
Compositions and methods relating to novel compounds and targets thereof
|
US7572788B2
(en)
*
|
1999-04-30 |
2009-08-11 |
The Regents Of The University Of Michigan |
Compositions and methods relating to novel compounds and targets thereof
|
AU5826100A
(en)
*
|
1999-07-13 |
2001-01-30 |
F. Hoffmann-La Roche Ag |
Benzazepinones and quinazolines
|
US6524623B1
(en)
|
1999-11-12 |
2003-02-25 |
Milton Hodosh |
Therapeutic compositions and methods of use thereof
|
JP2003532757A
(ja)
*
|
2000-05-11 |
2003-11-05 |
イーストマン ケミカル カンパニー |
アシル化シクロデキストリン:ゲスト分子包接錯体
|
US20020048566A1
(en)
*
|
2000-09-14 |
2002-04-25 |
El-Deiry Wafik S. |
Modulation of cellular apoptosis and methods for treating cancer
|
AU2002231098A1
(en)
*
|
2000-12-15 |
2002-06-24 |
Emory University |
Nonpeptide agonists and antagonists of vasopressin receptors
|
WO2003015703A2
(en)
|
2001-08-15 |
2003-02-27 |
The Regents Of The University Of Michigan |
Compositions and methods relating to novel benzodiazepine compounds and targets thereof
|
US7060705B2
(en)
*
|
2001-11-07 |
2006-06-13 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
EP1551812B1
(en)
*
|
2001-12-06 |
2009-03-04 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
EP1450901A4
(en)
|
2001-12-10 |
2005-05-25 |
Bristol Myers Squibb Co |
(1-PHENYL-2-HETEROARYL) ETHYL-GUANIDINE COMPOUNDS AS AN INHIBITORS OF MITOCHONDRIAL F1F0 ATP HYDROLASE
|
US20040009972A1
(en)
*
|
2002-06-17 |
2004-01-15 |
Ding Charles Z. |
Benzodiazepine inhibitors of mitochondial F1F0 ATP hydrolase and methods of inhibiting F1F0 ATP hydrolase
|
US20040087489A1
(en)
*
|
2002-11-06 |
2004-05-06 |
Antonio Ruiz |
Compositions and methods for the treatment of mycobacterial infections
|
AU2003293405A1
(en)
|
2002-12-03 |
2004-06-23 |
Vela Pharmaceuticals, Inc. |
Pharmaceutical composition of 1-(3,4-dimethoxyphenyl)-4-methyl-5-ethyl-7-methoxy-8-hydroxy-5h-2,3-benzodiazepine and uses thereof
|
JP2007500212A
(ja)
|
2003-05-01 |
2007-01-11 |
ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン |
新規化合物およびその標的に関する組成物および方法
|
US20050272723A1
(en)
*
|
2004-04-27 |
2005-12-08 |
The Regents Of The University Of Michigan |
Methods and compositions for treating diseases and conditions associated with mitochondrial function
|
US20060052369A1
(en)
*
|
2004-09-07 |
2006-03-09 |
The Regents Of The University Of Michigan |
Compositions and methods relating to novel compounds and targets thereof
|
EP1845996A4
(en)
|
2005-01-03 |
2009-04-29 |
Univ Michigan |
COMPOSITIONS AND METHODS RELATING TO NEW COMPOUNDS AND TARGETS
|
EP1893218A4
(en)
|
2005-06-01 |
2011-01-12 |
Univ Michigan |
NON-SOLVATED BENZODIAZEPINE PREPARATIONS AND METHODS
|
US20070105844A1
(en)
|
2005-10-26 |
2007-05-10 |
Regents Of The University Of Michigan |
Therapeutic compositions and methods
|
AU2006308655B2
(en)
|
2005-11-01 |
2010-09-23 |
The Regents Of The University Of Michigan |
Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties
|
US7759338B2
(en)
|
2006-04-27 |
2010-07-20 |
The Regents Of The University Of Michigan |
Soluble 1,4 benzodiazepine compounds and stable salts thereof
|