AU2005221195B2 - Modified annexin proteins and methods for preventing thrombosis - Google Patents
Modified annexin proteins and methods for preventing thrombosis Download PDFInfo
- Publication number
- AU2005221195B2 AU2005221195B2 AU2005221195A AU2005221195A AU2005221195B2 AU 2005221195 B2 AU2005221195 B2 AU 2005221195B2 AU 2005221195 A AU2005221195 A AU 2005221195A AU 2005221195 A AU2005221195 A AU 2005221195A AU 2005221195 B2 AU2005221195 B2 AU 2005221195B2
- Authority
- AU
- Australia
- Prior art keywords
- seq
- annexin
- protein
- linker
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4721—Lipocortins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55242804P | 2004-03-11 | 2004-03-11 | |
US60/552,428 | 2004-03-11 | ||
US57958904P | 2004-06-14 | 2004-06-14 | |
US60/579,589 | 2004-06-14 | ||
PCT/US2005/008193 WO2005086955A2 (en) | 2004-03-11 | 2005-03-10 | Modified annexin proteins and methods for preventing thrombosis |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2005221195A1 AU2005221195A1 (en) | 2005-09-22 |
AU2005221195B2 true AU2005221195B2 (en) | 2011-05-19 |
Family
ID=34976262
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2005221195A Ceased AU2005221195B2 (en) | 2004-03-11 | 2005-03-10 | Modified annexin proteins and methods for preventing thrombosis |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1734983A4 (ja) |
JP (2) | JP5134362B2 (ja) |
AU (1) | AU2005221195B2 (ja) |
CA (1) | CA2559167A1 (ja) |
WO (1) | WO2005086955A2 (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7635676B2 (en) * | 2001-02-21 | 2009-12-22 | Alavita Pharmaccuticals, Inc. | Modified annexin proteins and methods for their use in organ transplantation |
US7645739B2 (en) * | 2001-02-21 | 2010-01-12 | Alavita Pharmaceuticals, Inc. | Modified annexin compositions and methods of using same |
AU2009286244B2 (en) | 2008-08-26 | 2014-08-14 | Mosamedix B.V. | Radiolabeled annexins |
EP2742064B1 (en) * | 2011-08-09 | 2016-07-27 | UAB Profarma | Derivatives of recombinant proteins, homo-multimers of granulocyte colony-stimulating factor and method of preparation thereof |
GB2542391A (en) * | 2015-09-17 | 2017-03-22 | Annexin Pharmaceuticals Ab | Process of manufacture |
US11357823B2 (en) * | 2019-08-30 | 2022-06-14 | Suzhou Yabao Pharmaceutical R&D Co., Ltd | Method for treating cerebral stroke |
CN117897399A (zh) * | 2021-06-14 | 2024-04-16 | Inserm(法国国家健康医学研究院) | 突变的膜联蛋白a5多肽及其在治疗目的中的用途 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000002587A1 (en) * | 1998-07-13 | 2000-01-20 | Board Of Regents, The University Of Texas System | Cancer treatment methods using therapeutic conjugates that bind to aminophospholipids |
CN1247195A (zh) * | 1999-03-12 | 2000-03-15 | 中国科学院上海生物化学研究所 | 一种血栓靶向性溶栓融合蛋白 |
US6171577B1 (en) * | 1994-01-24 | 2001-01-09 | Neorx Corporation | Radiolabeled annexins |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3742675B2 (ja) * | 1995-06-28 | 2006-02-08 | 東菱薬品工業株式会社 | 虚血−再灌流障害の予防および治療薬 |
EP1839670A3 (en) * | 2001-02-21 | 2009-11-11 | Alavita Pharmaceuticals, Inc. | Modified Annexin Proteins and their use against thrombosis |
US20030152513A1 (en) * | 2001-09-06 | 2003-08-14 | Imetrix, Inc. | Intravascular delivery of therapeutic and imaging agents to stressed and apoptotic cells using annexin V as a targeting vector |
AU2003237351B2 (en) * | 2002-06-06 | 2009-12-03 | Tze Chein Wun | Novel recombinant anticoagulant proteins |
WO2004013303A2 (en) * | 2002-08-02 | 2004-02-12 | Surromed, Inc. | Modified annexin proteins and methods for treating vaso-occlusive sickle-cell disease |
-
2005
- 2005-03-10 CA CA002559167A patent/CA2559167A1/en not_active Abandoned
- 2005-03-10 AU AU2005221195A patent/AU2005221195B2/en not_active Ceased
- 2005-03-10 WO PCT/US2005/008193 patent/WO2005086955A2/en active Application Filing
- 2005-03-10 JP JP2007503052A patent/JP5134362B2/ja not_active Expired - Fee Related
- 2005-03-10 EP EP05725390A patent/EP1734983A4/en not_active Withdrawn
-
2012
- 2012-07-20 JP JP2012161761A patent/JP2012254992A/ja not_active Withdrawn
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6171577B1 (en) * | 1994-01-24 | 2001-01-09 | Neorx Corporation | Radiolabeled annexins |
WO2000002587A1 (en) * | 1998-07-13 | 2000-01-20 | Board Of Regents, The University Of Texas System | Cancer treatment methods using therapeutic conjugates that bind to aminophospholipids |
US6312694B1 (en) * | 1998-07-13 | 2001-11-06 | Board Of Regents, The University Of Texas System | Cancer treatment methods using therapeutic conjugates that bind to aminophospholipids |
CN1247195A (zh) * | 1999-03-12 | 2000-03-15 | 中国科学院上海生物化学研究所 | 一种血栓靶向性溶栓融合蛋白 |
Non-Patent Citations (4)
Title |
---|
http://search.cnpat.com.cn/Search/EN/) * |
SUN et al., 'Interaction of Annexin V and Platelets: Effects on Platelet Function and Protein S Binding' Thrombosis Research. 1993, Vol. 69, pages 289-296. * |
TAIT et al., 'Prourokinase-Annexin V Chimera' Journal of Biological Chemistry' 15 September 1995, Vol. 270, No. 27, pages 21594-21599 * |
THIAGARAJAN et al., 'Inhibition of Arterial Thrombosis by Recombinant Annexin V in Rabbit Carotid Artery Injury Model' Circulation. 7 October 1997, Vol. 96, NO. 7, pages * |
Also Published As
Publication number | Publication date |
---|---|
JP2008502592A (ja) | 2008-01-31 |
JP5134362B2 (ja) | 2013-01-30 |
AU2005221195A1 (en) | 2005-09-22 |
WO2005086955A2 (en) | 2005-09-22 |
EP1734983A4 (en) | 2009-11-18 |
EP1734983A2 (en) | 2006-12-27 |
WO2005086955A3 (en) | 2006-03-09 |
CA2559167A1 (en) | 2005-09-22 |
JP2012254992A (ja) | 2012-12-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC1 | Assignment before grant (sect. 113) |
Owner name: ALAVITA PHARMACEUTICALS, INC. Free format text: FORMER APPLICANT(S): ALAVITA, INC. |
|
FGA | Letters patent sealed or granted (standard patent) | ||
MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |