AU2005200878A1 - Animal Feed Supplement for the nutritional Enrichment of Animal Produce - Google Patents

Description

213/022005 21: 40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 04/63 WO 00/49889 WO 49889 PCT/AU00/00129 ANIMAL FEED SUPPLEMENT FOR THE NUTRITIONAL ENRICHMENT OF ANIMAL PRODUCE

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The present invention relates to nutritional enrichment of foodstuffs such as, but not limited to N pork, beef. poultry and the like and more particularly relates to the use of a selection of feed 0 supplements formulated for feeding to animals at predetermined stages of growth and which 00 include increased levels of omega 3 long chain fatty acids. The invention further provides feed o formulae for animals at various stages of development and which result in produce having an Sincreased human nutritional quality due to an increased level of long chain omega 3 fatty acids but without taint of the food product. Whilst the supplement and formulae of the present invention are suitable as feed for producing high nutritional quality beef and poultry (in the latter case influencing the nutritional value of poultry meat and eggs) the invention will mainly be described with reference to its application in pig feeding.

PRIBRARI

It is long established that there is a direct relationship between animal feed and the quality of food produce from a particular animal. An example of this relationship is evident where fish meal is used in pig feeding with theconstituent ingredient levels offish meal impacting on the nutritional quality of the food.

The food industry, in recognition of the desirability of lowering of saturated fats in the human diet has paid particular attention to improvement of the nutritional quality of foodstuffs and this begins with the animal feed blends. For instance, in the last ten years the average fat content of pork has been reduced by more than 50% in direct response to consumer demand for low fat diets in view of the links betwen high cholesterol, heart disease and a high fatdiet Animal products including pork also contain polyunsaturated fatty acids (PUFA). Pork and animal product 1 COMS ID No; SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 2B/02/2005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 05/63 SWO 00/49889 PCT/AUO/00129 0 0 producers have in recognition of the high nutritional benefits of long chain omega 3 PUFA and Sthe consequent high consumer demand for foods with high yields of these nutrients have 00 '00 paid particular attention lo the sources of these fatty acids and more particularly to ways of fortifying foods with long chain omega 3 PUFA.

00 r- Omega 3 polyunsaturated fatty acids, like vitamins, are essential to good health but as the body 00 o cannot itself manufacture these essential acids and vitamins it must rely on food sources for the o requisite supply of these necessities. Foods rich in long chain omega 3 fatty acids are generally 0 CN .not a regular part of the diet so most people are denied the full potential benefits of the presence of these in the diet.' Polyunsaturated fats are divided into the omega 3 and omega 6 fatty acids both of which the body needs. The effects of long chain omega 3 fatty acids on the body are significant as they are incorporated into every cell, tissue and organ including the heart and lungs, blood vessels, brain and joints.

There are a variety of food sources of long chain omega 3 fatty acids for example, Alpha linolenic acid (ALA) occurrs in oils such as canola, linseed (flaxseed), watnut and soybean as well as in green vegetables. Eicosapentaenoic acid (EPA) can be found in cod liver oil, fish oils fish and other seafoods and even in beef Docosahexaenoic acid (DHA) is found in tuna oil, other fish oils and in breast milk.

While omega 6 fatty acids are also beneficial and necessary for a good diet, the ratio of omega 6 fatty acids to omega 3 should be less than 5:1 and preferably 1:1, An excess of omega 6 acids can negate the effect of the long chain omega 3 fatty acids. Long chain Omega 3 fatty acids (EPA and DHA) are derived from fish and are more potent than the short chain omega 3 2 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 28/02/2005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 06/63 WO 0049889 PCT/AU0/00129 0 O derived from plants (ALA) as they are taken up directly by the cells. The evidence for the health benefits ofDHA and EPA in the diet is nowhere better demonstrated than in Japanese fisherman 00 and Eskimos who both have diets high in fish and a low incidence of heart disease. Omega 3 fatty acids also play a role in slowing the build up of fals on the walls of blood vessels, reducing 00 blood clotting, reducing blood pressure and decreasing arythmia. There is also evidence that 00 o omega 3 fatty acids can reduce risk of cancer and depression and can strengthen the immune N system, o The problem for the food industry has been to determine the most effective means of introducing long chain omega 3 fatty acids into the diet without compromising the physical, textural and sensory quality of the food vehicle. Egg producers introduced long chain omega 3 fatty acids into eggs by feeding hens foods such as fish meal which are high in these acids only to discover that the eggs tasted like fish leading to a reduction in consumption of such fat modified eggs. The hens were then fed a unique vegetarian diet of natural foods that are rich in long chain omega 3 fatty acids but there are significant restrictions on how much fatty acid can be introduced due to the problem of sensory taint. This is also the experience in the pork industry where fish meal has been fed to pigs to increase the level of long chain omega 3 fatty acids in consumers of pork, but the meat has also suffered from fishy taint which significantly reduces the level of omega three fatty acids which can be introduced.

According to conventional wisdom, high intakes by pigs of fishmeal as a source of long chain omega 3 PUFA above relatively low levels of 2 5% of the food vehicle results in pork taint manifested by decrease in oleic acid content, increase in iodine value hence oxidizability), as well as softening of the carcass fat. Thus there has traditionally in use of PUFA been a necessary 3 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 28/02/2005 21!40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 07/63 W oo/498S9 t WO0/49 PCT/AU0/00129 0 0 l compromise between achieving an optimum nutritional value associated with use of PUFA's C) while guarding against taint from excessive use.

00 This has kepi the use of PUFA's in pig feed to low levels primarily due to the undesirability of taint. The problems of taint and the desirability of increasing the PUPA content in the human r1- diet has been recognised in the industry literature; f see for instance the article entitled Omega 3 Enriched Pork" by Peter R.C. Howe Department of Biomedical Science, University of SWollongong, NSW, Australia]. For an enriched omega 3 product to be regarded as a useful C -dietary source it should be able to increase the level of omega 3 fatty acids present in the circulation when consumed in reasonable quantities. Although increases have been reported for comsumption of omega 3 eggs there has been no similar demonstration of potential benefit to humans with other alternative dietary sources of marine omega 3 fatty acids apart from refined fish oil supplements.

In recognition of the benefits of long chain omega 3 PUFA, the food industry turned its attention to identifying an economic and plentifil source of these acids. Fish oil was considered an obvious source of these fatty acids and experimentation was conducted to determine the levels which could be used in pork recognising that levels above a desirable maximum, could result in taint of the pork.

An industry objective has therefore been to determine the extent of omega 3 PUFA enrichment of animal produce that could be achieved using fish meal without the problems oftaint.

Experimentation found that only very low percentages 0.8 1.4% offish oil could be used in the diet and it was found preferable that the use should be terminated or reduced to the lowest levels before slaughter. The experiments demonstrated that increasing fish oil intake increased the 4 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 2e/02/2005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 08/63 WO 00/49889 PCT/AUO/0129 percentage of long chain omega 3 PUFA and therefore the nutritional qualities of the produce. It was also found that where diets contained 3% fish oil up to slaughter, the organoleptic quality of Fthe pork was affected. The industry then turned its attention to the use of fish meal as a source of 00 N long chain omega 3 PUFA for the enrichment of pork but taint of the physical and sensory 0 qualities of the pork remained a problem. The industry currently recommends that the fish meal 00 content of pig rations not exceed 5% of the total diet and only where the fish meal is withdrawn 0 S- 7 weeks before slaughter. Where the pigs are fed fish meal up to slaughter it is recommended Sthat the level offish meal in the diet not exceed The conventional source of fish meal is Cl pelagic fish, which when rendered into meal, normally has an oil content of6%- 9%.

The applicant has for some time (in order to meet the challenge of elimination of taint) been involved in experimentation to determine fish meal formulae for feeding to animals [depending upon the stage of development of the animal to which the food blend is fed] to optimise the retention of omega 3 long chain PUFA but without taint caused by the fish meal through off flavours and rancidity of the produce.

Although experts in the field have postulated as to possible ways to increase the use offish meal without taint of the produce, no one to date has succeded in increasing the fishmeal level above 3 of the total diet without risk of taint of the produce. Some in the food industry advise against feeding fish meal at any time during the 14 day period before slaughter to eliminate the possibility of taint.

The August 1998 issue of the organ of the Fishmeal Information Network commissioned an independant study by a pig nutritionist to review the available data on use of fish meal in feeding pigs. The study found that fish meal, provided that it does not exceed 10% oil content, can be fed at up to 7.5% of the diet without presenting any problems of taint in the end product, The COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 28/02/2005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 89/63 WO 00/49889 PCT/AU00/0029

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o findings do however recognise that for 100% security against taint, percentage levels of fish meal in the diet should be set below Thus it is generally recognised in the industry that it is

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Sundesirable to increase the percentage offishmeal beyond 3% 5% percent to be sure of 00 C elimination of taint.

INVENTION

00 The present invention seeks to ameliorate or eliminate the aforesaid problems of the prior art Srelating to taint in produce by providing feed formulae which optimise the level of use of 0 fishmeal in the diet of an animal, above percentages previously achieved and without the 0 Sproblem of taint through off flavours and rancidity. According to one embodiment of the invention, fish meal from cannery scrap of oily fish is used which produce a meal with 11%- 13% oil containing approximately one third of omega 3 fatty acids.

In its broadest form the present invention comprises: an animal feed supplement utilising fish meal as a source of omega 3 long chain fatty acids for inclusion in the diet of said animal; wherein, the fatty acids are increased to a level which maximises the nutritional value of the produce from said animal due to increased level of long chain omega 3 fatty acids but without taint of said produce.

Tn another form the present invention comprises: a fishmeal food supplement for feeding to animals wherein the content of omega 3 long chain fatty acids in animal produce such as pork, eggs poultry meat, beef and farmed fish is maximised to a level which is nutritionally optimal but without taint of the produce; wherein the percentage offishmeal food supplement is greater than 5% of the total dietry dietary intake of the animal, The percentage of supplement in the total diet of the animal is greater than 5% and preferably to produce the long chain fatty acids Decosahexaenoic Acid (DHA), Docosapentaenoic 6 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 28/02/2005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 10/63 WO 00/49889 PCTAU00/O0129 O acid (DPA) and Eicosap<ntaenoic acid (EPA).

c In another broad form the present invention comprises food supplement for feeding to animals in Swhich the level of long chain omega 3 is increased to increase the nutritional quality of the 00 N animal produceand without taint of the produce; wherein the supplement includes a blend of fish meal, an oil based premix, a drymix premix and water based green tea extract.

00 Preferably, the supplemnclt constituents are blended according to the following proportions; Skg Fish Meal 983.00 98.300 SOil based premix 10.00 1.000 C Dry mix Premix 5.00 0.500 water based green tea 2.00 0.200 1000.00 100.000 Preferbly the oil based premix ofthe supplement comprises a blend of the following ingredients; Ethoxyquin vitamin grade Crude palm oil Aniseed China Star Rosemary oil Thyme white oil Peppermint oil Benzoic Acid Bezoic Acid Phosphoric Acid 81% Crude Canola oil Carrier.

According to one embodiment, the constituents of the oil based premix per tonne of a food base are blended in the following proportions kg Ethoxyquin vitamin grade 0.400 4.00 Crude palm oil 1.500 15.00 Aniseed China Star 0.067 0.67 Rosemary oil 0.100 1.00 Thyme white oil 0,100 1.00 Peppermint oil 0.150 1.50 Benzoic Acid 0.005 0.05 Phosphoric Acid 81% 0.250 2.50 Crude Canola oil Carrier. 7.428 74.28 10.000 100.00 7 COMS ID No; SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 28/022005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 11/63 WO00/4989 PCT/ADOO/00129 0 0 Cl Preferably, the dry mix premix comprises a blend of the following ingredients; Vitamin E 50 Vitamin C SCitric Acid Propyl Gallate C Calcium-Propionate Wheat Meal Carrier Preferably, the dry mix prernix comprises the following proportion of constituents; 00 kg 00 Vitamin E 50 0.800 16.00 0Vitamin C 0.500 10.00 C Citric Acid 0.500 10.00 ti Propyi Gallate 0.100 2.00 SCalcium Propionate 0.500 10.00 C Wheat Meal Carrier 2,600 52.00 5.000 100.00 According to a preferred embodiment, the Vitamin C and Citric Acid are scavenger antioxidants.

In another broad form the present invention comprises a food supplement for feeding to animals to maximise the level of long chain omega 3 fatty acids in the animal produce and without taint of the produce; wherein the supplement comprises a blend of fish meal, an oil based premix and a drymix premix blended in the following proportions: kg Fish Meal 985.00 98.500 Oil based premix 10.00 1.000 Dry mix Premix 5.00 0.500 1000,00 100.000 In another form the present invention comprises a food supplement for feeding to animals to maximise the level of long chain omega 3 fatty acids in the animal produce and without taint of the produce; wherein the supplement comprises tuna meal, an oil based premix, a dry mix premix, water based green tea extract wherein the supplement includes the following constituents; 8 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 200502-28 2B/02/2005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 12/63 WO 00/49889 PCT/AUOO/00129 SFish Meal Ethoxyquin vitamin grade Crude palm oil Aniseed China Star SRosemary oil Thyme white oil Peppermint oil Benzoic Acid 00 Phosphoric Acid 81% Crude Canola oil Carrier.

SVitamin E 50 Vitamin C Citric Acid Propyl Gallate Calcium Propionate Wheat Meal Carrier

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00 OO In another broad form the present invention comprises a food supplement for feeding to O animals to maximise the level of omega 3 fatty acids in the animal produce and without V taint of the produce; wherein the supplement comprises fish meal, an oil based premix, Sa dry mix premix and water based green tea wherein the fish meal, dry mix premix and oil based premix collectively include the following constituents; Tuna Meal Ethoxyquin vitamin grade Cnrde palm oil Rosemary oil Thyme white oil Peppermint oil Benzoic Acid Phosphoric Acid 81% Crude Canola oil Carrier. Vitamin E Vitamin C Citric Acid Propyl Gallate in another broad form the present invention comprises a food supplement for feeding to animals to maximise the level of omega 3 fatty acids in the animal produce and without taint of the produce; wherein the supplement comprises fish meal, an oil based premix, and a water based green tea extract and a drymix premix including the following relative proportions ofconstituents; Y0 Tuna Meal (containing 11% 13% oil) 98.500 Ethoxyquin vitamin grade 0.040 Crude palm oil 0.150 Rosemary oil 0.010 Thyme white oil 0.010 Peppermint oil 0.015 Benzoic Acid 0.001 Phosphoric Acid 81% 0.025 9 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 28/02/2005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 13/63 WO 00/49889 PCTIAUDO/0O019 Crude Canola oil Carrier.

Vitamin E 50 Vitamin C Citric Acid Propyl Gallate 0,743 0.080 0.050 0.050 0.010 According to a preferred embodiment, the supplement further comprises the following consituent percentage proportions; Vaniliic Crystals Aniseed China Star Calcium Propionate Wheat Meal 0.013 0.007 0.050 0.260 In another form the present invention comprises a food supplement for feeding to animals to maximise the level of long chain omega 3 fatty acids in the animal produce and without taint of the produce; wherein the supplement comprises fish meal, an oil based premix, a drymix premix, and water based green tea extract blended in the following proportions per tonne of food base' Tuna Meal Ethoxyquin vitamin grade Crude palm oil Aniseed China Star Rosemary oil Thyme white oil Peppermint oil Benzoic Acid Phosphoric Acid 81% Crude Canola oil Carrier.

Vitamin E 50 Viaminn C Citric Acid Propyl Gallate Calcium Propionate Wheat Meal Carrier 985.000 98.500 0.400 0.040 1,500 0.150 0.067 0,007 0.100 0.010 0.100 0.010 0.150 0.015 0.005 0.001 0.250 0.025 7.428 0.743 0.800 0.080 0.500 0.050 0.500 0.050 0.100 0.010 0.500 0.050 2.600 0.260 1000.000 100.000 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 20/022005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 14/63 WO 00/49889 PCT/AU00/00129 O The fish meal may be selected from Tuna, Mackerall, Sardine, Pilchard or Anchovies but it will be C appreciated that marine fish oil may be derived from other species.

SAccording to the method aspect of the present invention there is provided a method of 00 0, feeding animals using a fish meal based food supplement with 11% 13% fish oil wherein the Ssupplement comprises at least 5% 20% of the animals' total diet wherein the method comprises the following steps: 00 Sa) selecting constituents bfr a supplement including fish meal, an oil based premix, a t dry mix premix and a water based green tea extract 0 C b) preparing the dry mix and the oil based premix: c) blending the constituents in predetermined proportions of the supplement; d) selecting additives for the supplement appropriate to the stage of development of the animal and blending the additives with the fish meal, oil based premix, dry mix premix and water based green tea extract; c) feeding an animal with the supplement blended according to the stage of development of the animals selected for feeding so that the food produce from said animals has an optimum level of long chain omega three fatty acids yet is free from taint and wherein the supplement may comprise between 5% 20% of the total diet of the animal.

According to another form of the method aspect of the present invention there is provided a method of feeding animals using a fish meal based supplement at a level within the range of 10% of the animal's total diet, wherein the supplement comprises the following active ingredients Tunn Meal Ethoxyquin vitamin grade Crude palm oil Rosemary oil 11 COMS ID No: SBMf-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 2B/02/2005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 15/63 1n WO 00149889 PCT/AU00/0129 o Thyme white oil C Peppermint oil Benzoic Acid Phosphoric Acid 8 1% Crude Canola oil Carrier.

0 Vitamin-E Vitamin C Citric Acid 00 Propyl Gallate 0 0 wherein the method comprises the following steps: 0 a) selecting constituents for a supplement including fish meal, an oil based premix, a o dry mix premix and a water based green tea extract b) preparing the dry mix and the oil based premix; c) blending the constituents in predetermined proportions of the supplement; d) selecting additives for the supplement appropriate to the stage of development of the animal and blending the additives with the fish meal, oil based premix, dry mix premix and water based green tea extract c) feeding an animal with the supplement blended according to the stage of development of the animals selected for feeding so that the food produce from said animals has an optimum level of long chain omega three fatty acids yet is free from taint and wherein the supplement comprises between 5% 20% of the total diet ofthe animal.

According to a preferred embodiment the method comprises the further step prior to or after blending of the dry mix and fish meal of: a) preparing the ingredients of said oil emulsion according to the following mixing sequence; Crude Canola Oil Crude Palm Oil Phosphoric Acid 81% Benzoic Acid 12 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 28/02/2005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 16/63 WO 00/49889

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PC2AUOO/aOO29 0 o Ethoxyquin Vitamin Grade Aniseed China Star Rosemary Oil 4 Thyme White Oil 00 Peppermint Oil

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b) high speed mixing of said ingredients to create a homogeneous stable emulsion 00 According to the preferred embodiment, the method includes the following step prior to 00 Ssteps a) and b) last mentioned above of preparing the ingredients according to the Cl following steps: Si) heating to above 50 degrees C to liquify the Crude palm oil; ii) heating to above 22 degrees C to liquify the Aniseed china star iii) heating to above 20 degrees C to liquify the Crude Canola Oil, According to a preferred embodiment the method comprises the further step prior to or after blending of the oil emulsion and fish meal of preparing the dry mix by combining the following ingredient sequence; Wheat Meal Vitamin E Vitamin C Citric Acid Propyl Gallate Calcium Propionate Green Tea Powder Vanillic Crystals According to one embodiment of the method aspect, the Oil Emulsion may be applied by fine spray to the Fish(Tuna) meal; the Aqueous Extraction to be applied by fine spray to the Tuna meal; the dry mix io be added to the Tuna meal followed by mixing the whole to produce a homogeneous blend. Nutritional Premixes supplying the Vitamin, Mineral requirements of particular species and stage of life cycle/development may be included in the supplement to satisfy the nutritional completeness of the appropriate supplement According to the invention, the feed supplement provides a supply of long chain fatty acids 13 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 2e/02/20OF3 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 17/63 WO 00/4989 PC/AUO/00129 0 C such as DHA, DPA and EPA in contrast to the short chain fatty acids which are obtained from ,.certain vegetable sources.The long chain omega 3 fatty acids will be absorbed directly into the 0 animal body in their existing biological form exerting beneficial physiological change and direct deposition in the blood stream, body cells and fat depots unlike the Short Chain Fatty 00 0 Acids which require conversion by the animal to long chain fatty acids which is inefficient 00 00 Sand poor yielding.

T DETA .LD DESCRIPTION SThe present invention will now be described according to preferred but non limiting embodiments and with reference to various examples wherein; Figure 1 shows a schematic layout of a typical process for the preparation of a feed supplement according to one embodiment of he invention.

Annexure I shows a variety of supplement formulae according to various embodiments of the invention and adapted for feeding at various stages of development of an animal.

The supplement blends according to the examples to be described provide a consistent high source of omega 3 long chain fatty acids, especially DHA in animal diets to thereby increase the intake of omega 3 long chain fatty acids in the human diet. The supplement blends have been found to eliminate taint of the resultant produce and to enhance the flavour of the produce.

Conventional wisdom prior to the the invention required the implemcntation of at least a 14 day fishmeal exclusion prior to slaughter to avoid fish taint. This 14 day exclusion period presents practical difficulties on farms where the producer is forced by fann circumstances to operate with a single stage finishing diet. In some cases it could lead to the withdrawal of fishmeal in the diet at a much earlier stage with possible adverse implications for livestock health, There is concern 14 COMS I0 No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 29/02/2005 21: 40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 18/63 WO 00/49899

CTAUOGO

-PCT/AUO0/00129 that the 14 day exclusion could be increased for many weeks and posssibly up to 12 weeks.

Experts currently believe that when feeding fishmeal up to 5% of the dietary intake of the animal

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F4 there is a comfortable safety margin for eliminating off flavours in the animal produce, provided 00 (N that as an added safeguard fishmeal is excluded from the diet two months before slaughter.

OO The present invention challenges convention wisdom and overcomes the problems of prior art 00 fishmeal feed formulae by providing a range offishmeal feed supplements which may be Ssignificantly above the currently recognised upper percentage limits for elimination of taint but Swhich do not result in taint of the produce.

0 <C Taint in foodstuffs is normally determined by a Sensory Panel of experts who are trained in determining whether a particular foodstuff has certain taste characteristics. Thus one expert may have a proven sensitivity to sweetness, in cheese and another in meats. Other experts can determine whether animal produce is tainted with a fishy taste after feeding with fish meal.

Trials were conducted to determine whether animal produce from animals fed with the feed supplements and associated formulae according to the present invention were tainted, Although prior to the invention, experts believed that fishmeal supplements greater than 5% of the total diet of the animal would lead to fishy taint, the Sensory Panel evaluating the Supplements and formulae according to the invention (marketed under the trade mark name Porcomega) fed to pigs found that supplements greater than 5% of the total diet of the animal did not result in taint of the produce.

Tests on the effects on animal produce offish meal supplements according to the invention and greater than 5% of the total diet of the animal were carried out in the Commonwealth Scientific and Industrial Research Organisation Department of Human Food Nutrition in Adelaide, Australia, The panel found that the produce tested did not suffer from fishy taint.

COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 F A J 28/02/2005u 21l:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 19/63 WO 00/49889 PCT1AUI000129 0 Preferably, the percentage range of fishmeal with fish oil content between 11- 13 in the diet Sof an animal in which omega 3 fatty acid enrichment is required is 20%. Due to the blends of the supplements used, the fishmeal may be fed up to slaughter in these percentages.

00 Figure I shows a schematic layout of a typical process for the preparation of feed supplements 00 according to the method aspect of the present invention.

r- 00 According to the method aspect of the invention, quality control is most important for conformity of the finished supplement and its raw materials, As a matter of routine practice, the constituent O ingredients should be checked for physical conformity and condition. Preferably, chemical analyses are carried out and with checks for any infestations from insects etc. The ingredients must be free from rancid, musty, stale or any other objectionable odours Therefore, thorough physical examination is important.

Prior to the start of each production run and after any extended downtime, the process line is evaluated to verify that Ihe line is in satisfactory condition and that all controls are calibrated and functioning. This is described as calibration step 1.02.

Step 1.I involves the preparation of the dry mix wherein bulk ingredients L.11 are selected according to the particular formula, followed by calibration step 1.12 involving weighing out bulk ingredients. The ingredients are then transferred for mixing, Step 1.3 is preparation of the oil based premix. Preparation of the oil based premix involves the following steps. The raw materials are selected and weighed 1.31 according to the selected formula. These materials are mixed 1.32 by stirring with preweighed preheated 70 degrees C oil carrier in a steam jacketed mixing vessel. The mix is then held for quality control step 1.33 followed by calibration step 1.35 wherein the mix is metered into the dry mixer according to formula.

Step 1.4 is the preparation of the Dry Mix Premix. Step 1.41 is the selection and weighing of the 16 COMS ID No: SBM -01141828 Received by IP Australia: Time 22:52 Date 200502-28 28102/2005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 20/63 WO 00/49889 WO 004889 PCT/AUOO/00129 ingredients according to formula. In step 1.42 the ingredients are mixed together followed by quality control step 1,43 and calibration step 1.44 wherein the mix is metered into the bulk dry mixer according to formula. The next phase step 1.5 involves the following procedure. Step 00 N is the selection and weighing of ingredients according to formula, In step 1.51 ingredients are 00 added to preweighed water heated to 100 degrees C in the steam jacketed reaction vessel -0 followed by mixing step 1.53. In step 1.5.4 a preweighed Green Tea ingredient retained in a cloth 0 0 bag is infused into the mix, In step 1.55 the green tea is extracted for 30 minutes and the spent Green Tea is discarded. Step 1.56 involves metered mixing according to formula into the N bulk dry mixer. According to steps 1.15 to 1.19 the mixture is mixed for 10 minutes until it is homogenous following which the mixture is discharged and sieved through a 2mm screen wherein the tailings are discarded. The mixture is then subject to quality control. According to steps 1.6 to 1.63 the mixture is released for weighing, checking, packing and despatch.

Trials in human volunteers were undertaken to test the hypothesis that regular consumption of pork enriched with long chain omega 3 fatty acids will lead to increased levels of these fatty acids in the circulation and resultant improvement in cardiovascular health.

The trial objective was to conduct a preliminary dietary intervention study with pork from pigs fed with supplements according to the present invention to determine of there would be any increase in the levels oFEPA, DPA or DHA present in the plasma fatty acid pool or in erythrocyte RBC) membrane phospholipids in human volunteers eating lean cuts of pork over a 4 week period. The tests endeavoured to determine whether the increase in omega 3 fatty acid supplementation would influence the two health parameters that are reportedly most responsive to omega 3 fatty acid supplementation namely reduction of plasma triglycerides and platelet thromboxane production.

17 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 2B/02/2005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 21/63 WO 00/49889 it PCT/AUOO/00129 0 A study was conducted to determine how much omega 3 enrichment could be achieved using fish meal. Nine week old pigs were fed a ration containing 20% of a high grade fishmeal supplement 00 formula according to the present invention. EPA, DPA and DHA accounted for 1.9, 0.5 and respectively of total fatty acids in the diet. There were negligable amounts in a control diet.

00 Groups of three pigs were fed the control diet for 7 or i weeks or the fish meal diet for 6 to 0 0 weeks before spaughter Growth and feed conversion rates were similar in control and fish meal Sfed pigs. In the latter, omega 3 consumption averaged 15g/pigday which resulted in striking increases in the plasma levels of DHA and particularly EPA. In the week before slaughter the high circulating levels declined but there was signifiani retention of long chain omega 3 polyunsaturated fatty acids including DPA in lean portions sampled from various cuts of fresh pork which increased with the duration of feding. Graph I below depicts relative proportions of long chain fatty acids in selected outs ofmeat from pigs fed a control diet ot the fishmeal supplement according to the invention for 10 weeks. Graph 2 shows omega 3 concentrations in selected cuts of meat from pigs fed a control diet of the fish meal supplement according to the present invention. The proportion of long chain omega 3 polyunsaturated fatty acidsin lean loin chops 4.3% fat) rose from 1. 1% in controls to 6% in the fish meal fed pigs representing a yield of 250mg/100g of fresh meat. In forequarter chops the proportion was less(4. but he fat content was higher( 8.7%).lence the omega 3 yicld was even greater: 3 6 0mg/00g. Furthermore the surrounding layer of fat contained five times as much long chain omega 3 fatty acids. The study indicates that the omega 3 yield of pork products fed with a supplement according to the invention will depend upon their overall fat content.

18 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 2B/02/2005 21:40 +61-2-95522894 WALSH AND ASSCIATEA PAGE 22/63 WO 00/49589 PCTAUOQI00U9 ui..nA ADO Mliuretime AG s." Lifretinue average daily gain GRAPH I Chrge In IUvew lgh 1 3

FP

I

0 En~h 214O 56d 112 d 147 d Age (SI GRAPH 2 Chbnge in Liveweight aver Time.

COMS ID to: SBMI-01141828 Received by IP Australia: Time 22:52 Date (Y-Md) 2005-02-28 28/02/2005 21:40 +61-2-95522094 WALSH AND ASSOCIATES PAGE 23/63 WO 00/49889 PCTAU08029 Twenty seven volunteers participants and their partners completed the sensory evaluation of 0cooked pork. The results appear in Table I below and demonstrate no significant preference for either the n-3 enriched pork or the control pork, Most importantly the volunteers did not detect any preference for one pork over the other indicating that there was no detectable taint in the 00 pork.

0- 0

TABI-

Sensory evaluation of pork.

prtfer Porcomega prefer normal pork no preference Loin taste 7 12 8 smell 5 2 mouthfeel 1 8 Forcquarter taste 6 10 11 smell 6 6 mouthfeel 7 9 11 OVERALL 7.0 7.8 12.2 Detailed studies have been carried out on the carcasses of pigs fed with the supplement formula according to a regime commensurate with the stage of developmnt of the pig-Results of the arnalyses of the carcasses vary according to the site, Tables 1-5 below set out examples of the formulae of the food supplements according to various embodiments of the invention. It was found that there were no significant dietary effects of the inclusion of the supplements according to the invention, fishmeal or fish oil on growth rate and slaughter characteristics of the pigs in COMB ID No: SBM1-01141828 Received by IP Australia: lime 22:52 Date 2005-02-28 28/02/2805 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 25/63 WO 00/49889 FCT/AUOO/00129 o this study. The meat from all diets were found acceptable to consumers, None of the produce c from Diets 1-5 were considered unacceptable. The determination of fatty acid profiles in meat 4 samples was carried out by Professor Len Storlein of the Biological Sciences Department of the 00 University of Wollongong New south Wales The dietary supplements are tailored to suit the 00 stage of development of the pig. Of the Diets identified below, Diet 5 is the least preferred in 00 favour of diets 1 4.

O TABLE 2 DTETS r- *n I CONTROL 2 CONTROL 3% FISH OIL 3 15% SEAPEP 4 15% SUPPLEMENT ACCORDING TO THE INVENTION Porcomega) 15% SUPPLEMENT ACCORDING TO THE INVENTION Porcomega)+ 3% FISH OIL The following examples show that the omega 3 long chain fatty acid content of pork is significantly increased in pigs fed supplements in accordance with the present invention. The examples tabulate the fatty acid profile of phospholipid and Triglyceride from specified sites of male and female pigs for each of the diets identified in Table 2.

21 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 28/02/2005 21:40 28/0/205 2:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 24/93 WO 00/49ft9 EXAMPLE

I

1111Cy Acdl 1-jiI$1kj j DI IA I'A ,DpA U f P~siopi rm1uc ie ILUiln. lxg. P Uft(1Uii'cr J 111 5 MALE 1311GS.

MO1iT DRA ESPA DPIA UEn 11-3 nU/nl3 I oll lx~j1.7 177 0-743a J.0755 5.035 7.044 2. Lkmivol CI1%Irishi Oil 4.5484 4-T713 1.2947 11.679 2.807 *3.1 113% s4'phj 5.5875 2.004 1.0813 1 1.0:t7 :1,088 4.15% Porcrnngat 5.8751 4.2736 1.8344 12.941 2.00 5.15% fl(unvoIIhgufR.3vyraJ 011 9,40416 3,0052 0.7113 13,181 2.210 ls or Fin.1) D1 V-1 DUMA EPA DPA Thin!l n-3 n(3i,1a 1. Cirp1.2720 0.5703 1.0655 4.2150 9.033 2. Confini -3%rII1 il 6n.0598 4.8659 1.45511 13.309 1. D43 3 1 5 Scnipej 0.2464 1,9129 2.0720 11.370 2.9941 4. 15%I Porvuogn 8.5052 3.0288 [.0103 12.544 2.1J05 5.15% Po01toanegnl+a%g.1 1 Oil 7.5433 5.02 10 0.0000 13 161

I

4UQ SJ154, Alvu rik"tlj 4.1,5% !'0"Cauiwgo 15% i'or-cw;hiacgn.-1a%? 1 81 1 0jJ DMA IM'A [WA Toltal nj.3 1-100 064M0.8071 3.0516 0.3320o51osbo 1.525f3 14.29.j 0.7 154 0.5542 1.L03031 10,.I 8j 7.65284.0347 0,18IG J13,3191 8.3222 5.0940 0.000oo 13,332 10.43o 2. 160~ :1.2.34 2.31.( 1.880 COMS ID No: SOMI-Ol 141828 Received by IP Australia: Time (H:rn) 22:52 Date 2005-02-28 2B/02/2805 21:42 +61-2-95522994 WALSH AND ASSOCIATES PAGE 26/63 W) 00/49889 PCT/AUOP/oo129 EXAMPLE 2 d0 m 7 Acly I'IbIIIC F lfIA r F3A q OV hr inkpillpild Irv0i1 ,l I1r-c S's 00 00 uIAi.LCJ. 1?rOMgp1iiurCI 111 5 ILMIJA3 LOIN hIs 14 K oF- 00 omur 1. Co111,01 2. Ccuarcl 4-JFialt 011 3.15f% se-upel 4 .J 5% Pviroia Igp 15% I'ureromc-ga+ ris I, D1R J&NA DI'PA TIra n.3 2.7058 ].5085 1 .568 6.941 6.4429 0.2J43 1. 1551 15.5(4 (I .1105 3.D-910 1.92U 12.545 6.3399 5.9938 2.3028 16.132 Oil 7.0822 7.;Th 8 1.8541 17,37 FT(310 5.430/ 2.020 2-018 1.073 EXAMPLE 3 irouy Acdd Irofll f 13 IA. 917A DPA j of 'l-Igyccrlc frunil 'lir~e Sites Lon, Ieg. rriimuaric I in 5 FEMALE 1PIGS.

LoN (ais cF inlg 138I' UlA rw7A DI'iA Total n-3 miG/n 0.2110 0.0510 0.1273 0.585 20.543 2. Control 1%InlIb O11 0.8101 0.2441 0.3250 1.084 1.841 3. 13SH Ieyc) 0.0097 0.0000 0.0000 0.010 3.061I 4 .15 I'orvowcgn 0 0.84 10 0.3872 0.OO0 1.228 3.070 5.115% I'imorncgn3%;rgsh 1 Oil 0.71660.2830 1.1113 2.111 0.8D2 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22;52 Date 2005-02-28 2B/02/2005 21:40 26/8/285 2:48 +61-2-95522894 WALSH AND ASSOCIATES PG 86 PAGE 28/63 WO 00/49399 PCr/AUOO/007290 0 EXAMPLE 4 Filtly Aid Proffin C DEJA L-M1'A DPA of T'rlglyceaide fromn 7larce Slics 00 1 i. 4. Forcciunrlcr IIn %4 MALE PIGS.

1,01N fasq of PAl) 00 lII!r 11DILA EWA DPA Ibtal n-S nOl113 00 1. Cuimirol1 0.3040 0.0000 0,1057 0-740 11.041 o2. Control -i 3%FIsh Ofil 4.2850 1.3301 0.0500 0.073 1.801.

3,.15% Scnpop 1,3039 0.2781. 0. 1503J 1,792 3.222 4, 415% Porwcnga J1,55300,3821 0.1366 2,072 2.720 151% l'orca'hcga+3%IrIsIi ON11.7741 a.5W8o 0.2049 2.G08 1ID A trial using 25 large white female pigs arnd the above Diets was commenced on 12 December 1996 With a (mean lightweight 21.5 kg) running through slaughter on 12 March 1997. At slaughter the pigs were weighed arid values recorded. Sub samples from each sex and dietary treatment were taken for taste end taint evaluaionS.'Jjer Were no signs of significant weight gain. There were no apparent differences in weight gain of the male pigs due to dietary treatmnr. A similar result occturred with females and there were no significant differences due to type Of fishimeat or oil added to the diet.

The foliowing table 3 shows carcass and performance data for female pigs.

Combined (male and fernale statistical analysis of Figure 2 and (able 2 showed a significant difference (P=0.OO0 1) in dressing percentage between the male and female pigs. The clThct af sex approached traditionsl significance P=0).06) for ADCO. Ther were no significant efl-ets of diet type of fishmeal or oil) on any parameter nor any significant interactions of sex and diet.

24 COMS ID No: SBM -01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 28/02/2005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 29/63 0 ri 00 o oo oo 0 0 0q

(N-

WO 00/49889 PCT/AUU0/00129 TABLE 2 Diet No Slaughter Wt(kg) DR% P2(mm) Gain (kg) ADG (gd) LWT DWT 1 5 100.4 69.4 69.1 18.8 79.0 888 2 5 103.8 70.7 68.1 18.2 81.9 920 3 5 102.1 70.7 69.3 15.2 81.2 912 4 5 100.1 69.3 69.2 18.6 79.3 891 5 5 103.7 73.0 70.4 17.4 81.3 914

CI-

Avtrage daily gain calculated uvar an 19 day period.

Meat from each diet were evaluated for taste and taint Meat was cooked in boiling water for minutes. Small pieces of Im3 from each treatment were evaluated for pork taste with reference to a scale of 0-10 in which 10 is extremely tasty and for taint on a scale of 1-10 in which 10 is extremely tainted. The results of the tests are set out in table 3 below.

TABLE 3 The effect of diet on the taste and taint of male and female pig meat.

Diet-- Subjects SE* Tainl(O-l 0) SE Diet Subjects Taste(0-10) SES TainL(0-10)

SE

1 10 6.65 0.49 1.15 0.63 2 10 5.80 0.49 1.95 0.63 3 10 5.75 0.49 2.45 0.63 4 10 5.10 0.49 3.30 0.63 10 4.20 0.51 4.35 0.64 Standard error of the mean.

There were no significant effects of sex (of pig) on either taste or taint in this test. The results indicate no deleterious effects on either growthrate, carcass yield or carcass characteristics.

Analysis indicates that the feed supplements according to the invention enhance the omega 3 long chain fatty acids content of the meat. The feed supplements may be used with or without withdrawal periods prior to slaughter.

COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 213/02/2005 21:40 20/8/285 2:48 +61-2-95522894 WALSH AND ASSJCIATES PG 06 PAGE 3e/63 WO 00/49889 .PMrAU00w00129 o Clinical trials show a beneficial thromboxane result having the desired consequential Cl physiological effects.

A good measure of ration efficiency is the amount of feed required by a growing animal for it to 00 gain a unil of weigla. Feed represents 60[-70% of the running costs of a piggery. It has been Nl estimated that a 0. 1 unit change in feed ernlciency is worth about AUJ$40/sow/year in terms of 00 feed. During the lactation phase, PFM fed sows consumed approximaieiy 84g of feed each for 00 o a net gain of 10 kg. Based on this their feed gain ratio was Over the same period the feed gain ratio for die pigs fed with tlie supplement according to the inventiu was 3.7:1 (74k&g feed for 0 20kg gain). The Graph 3 below shows feed gain ratios and it can be seen that gain for grower pigs was best for those fed supplement according to the invention 3. 1) followed by PPM pigs and control pigs( A taste pane? found that titere waS a prefe-rence for pigs fcd with Lhc supplement a fihe PPM pigs suffered from fi shy taivut wh ich was detected by allI members of the taste panel.

GRAPH 3 -Jr ra i A-26 COMS IDNo: SBMI-01141828 Received by IP Australia: lime 22:52 Date 2005-02-28 28/02/2005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 31/63 WO 00149889 PCYTAUOO00129 0 0 Annexure I sets out a range of supplement formulae according to embodiments of the invention which relate to the stage of growth of an animal which is fed the supplement.

It will be recognised by those skilled in the art that the compositions and supplement formula N disclosed are examples only and that these or variations thereof may be fed to other animals such 0 as but not limited to beef, cattle, sheep and poultry to achieve the objects of the invention and as 0- 0 such are therefore within the spirit and scope of the invention broadly described herein. For Sexample, the consistency of the premixes before addition may be varied. The flavour of the o system may be altered for instance using Fenugreek.

27 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 2e/02/2005 21:40 +61-2-95522994 WALSH AND ASSOCIATES PAGE 32/63 WO 00/49889 PCT/AOO/00129 1. FORMULA IPltit TONNE PORCOMEGA' PIGLET STARTER EW 001 00 00 0 0 0 0 11OCOMRGA* BASE- SP VrrAMIN PREMIX PV 001 MINERAL PREIMIX PM 001 AMINO ACID PRIEMIX PAA 001 Ci1OLIN; CIiLOIUDE 60% 970.80 2.50 10.00 10.00 1.70 1000.00 97.080 0.250 1.000 1.000 0.670 100.000 USAGE 150 1(0 [ER TONNE OF PIGLET STARTER EW DIET.

1. P[G S'ARTER EW VITAMIN PREMIX PV 001

COMPOSITION

INGRIED I!TI

ACTIVE

POTENCY/OM FORMULA /Kg PRE1MIX VITAMIN A-500 500.000 IU VITAMIN 03-500 500,000 IU VI'AMIN E-50% 500 IU VIlAMIN 13 1000 mg THIAMINE IIYDROCHLORIDE USP 892 nmg RI13DOLVAVIN 95% F.G. 950 mg PYRIDOXINE USP 823 mg VITAMIN B12-SUPPLEMENT 1% 10 mg NIACIN USP 990 mg CALCIUM I-PANTClIIENATE UISP 920 mg FOLIC ACID USP 920 mg D-3IOTIN SUPPLEMENT 1% 10 mg GOREEN ThA POWDER -4t/ flA/i1 1000 tug VANILLIC CRYSTALS 1000 mg WHEAT MEAL CARIWER 53.60 gmn 13,40 gm 52,80 gin 4.02 gm 4.51 gmn 11.28 gm 6.51 gmn 5.30 gm 54.14 gm 34.96 gm 4.37 gin 21.44 gm 120.00 gm 53.60 gm 560.01 gm 1000.00 gm 26.800.000 IU 6,700.000 1U 26.400 IU 4.02 gm 4.02 gm 10.72 gm 5.35 gm 53.60 mg 53.60 gm 32.16 gm 4.02 gmin 214.40 mg 120.00 gm 53.60 gm USAGE: 2.5 Ig per Tonne Porcomnega* Pig Starter EW Supplement 001.

8/ COMS ID No: SBMI-01141828 Received by IP Australia: ime 22:52 Date 2005-02-28 28/02/2005 21:40 +61-2-95522894 20/02/005 2140 4-6 -2-0522894WALSH AND ASSOCIATES PG 36 PAGE 33/63 WO 00/4999 Pa/AU00o29 0 0 ci ~0

C)

00 cx', r 8.

PIG SiA1UrlLzl EW- PORCOMEGA9 ANlD COMPLE FEED VITAMIN AonrriOr 00 00 0 COMPQSMTON AUrIVE INGR~hIN'j fMnne PoRCOMEG.AS VITAMIN A-5i(U 67.000.000

ZU

VIAMIN 03,600) 16.750.000)

[U

VITAMIN E-50% 466.000 IUl VrTAM IN K'3 10.05 gum THI1AMINE IIYDIROCHnLORDE lISP 10.059 gui 05% F.C. 26.80 gmi PYRID)OXINE LISP 13.40 gmi VITAMIN III2-SUpttI!r.MEpN 1% 134.00 mg NIACIN uISP 134.00 gui CALCIUM L-PANTOrHENATE- U~p 80.40 grn F OLIC ACID LISP 10.05 gmn SUPPLEMENT 1% 536.00 mng 1CHOLINE CHLORIDE 4020.00 gmi GRE EN 'lA POWDERZ 300.00 gui VANILEIC CRYSTALS 134.00 grn

ACTIVE

jKg CO MPLETE F EED 10,000 IU 2.500 LUi 69.5 fu 1.50 mng 1.50 Mg 4.00 mug 2.00 mig 20.00 rncg 20.00 mug 12.00 ing 1.50 rug 80.00 mcg 600.00 rug 44.77 rng 20.00 mg

ACTIVE

1Kg PREMDC 6 7.000 gm mn 6 7 .000 gm M' 26.800 gm "1Ix STARTER:1 EW MINERAL, PREMiX PM 001 INGIIE ME M'

POTENCY/GMI

FERROUS SULI1 IA7E 100M (Fe 8 S04.1-1201 ZINC STJLPI lATE MANGCANESE SULPHATErc (Mn 504.1120) POTASSiM IOOIDE(S1f) QOI)3ALT CARB3ONATE CO1PPc-R1 SULP].uyrE SODIUM SELENrMt I t tn,. 360.0 mng 280.0 rug 68.8 Mg 460.0 mng 250.0 rug 400. 0 nag 1

ORMULA

216.125A 186.ll10 95.715 g 0.488 gmi 0.728 gmn 335.000 ami 0.504 grn 0.335 gui 0.335 gmi 83.750 gyn 0.201 grui -4VISI Clul~l1000.0 Mg 165.330 gmi 155.3 1000.Ooo gui USA E: 0 K pe Th ne Porosn gue Pig Strter EW supplement ooi.

30 gm COMS ID No: 5DM -01 141828 Received by IP Australia: Time (I-tm) 22:52 Date 2005-02-28 2e/02/205 21:40 +61-2-95522894 WALSH AND ASSDCIATES PAGE 34163 WO 00/D988p 00 00 00 00 PCTAUO/ffip29 9.

PIG, STRmLRi EW PORCOMEGA0 AND COMPLLMnr PEED MINERAL ADLrror COMPO)SIImON

ACTIVE

INGIREDIENT Tonne PORCOMEGA- I'ERRIOti.s S[U~pHqATE-e 670.00 gin (Ve S04.1-120) ZINC SULPIHIATE-Zn 670,00 gm MANGANESE SULPUAmTF-Mn 268.00 gin (Mn S04.120) POTASSIUM IODIDE(STABI..I 3.35 gm COBALT CARBONA~r-Co 3.35 gm

ACTIVE

/Kg COMPETE FEED 100.500 ing 100.500 mg 40.200 mg 0.502 mg 0.602 'rg 125.625 mg 0.301 mg COPPER SJLPHATE, -Cu SODIUM SWLENITC -Se 2.01 gin PIGLET STARTER rW AMINO ACID PREMMc FAA 001 COMPOSI1ON

INGREDIENT

-LYSINE

di-MET TjONINC TIIRE ONINE WHEAT MEAL CARIER FORMtL 0700.00 gn 1340.00 gin 1340.00 gri 620.0o gmn 10000.00 gin 1Kg PREMIX 670.00 gin 134.00 gin 134.00 gin USAGE 100 PER TONNE OF PORCOMEQA' PIGLET STARTER EW 001.

AMINO ACID) ADDIIONS 1-LYSINE di-METHIONINE

THREONINE

/Thnne PORCOMEOA* 6700.00 gin 1340.00 gin 1340.00 gm /Kg COMPLETE FEED 1000.00 mg 200.00 mg 200.00 mg 101 COMS ID No: SBMI-1141828 Received by IP Australia: Time 22:52 Date 2005-02-28 2B/02/2005 21:40 +61-2-9552294 WALSH AND ASSOCIATES PGE 3563 WO 0W49839 FCTIAUOO00129 P0RCOMEOGA PIGLET STARTE R EW SUPPLEMENT 001 Th4EOREI1CAL ANALYSES TBA r ,/AZ AS'l.

D.E. S/Kg CALCIUIM CRUDE FIBRE PHOSPHORUS (Total)% CRJDE PILOTEIN CRUDE xrAT LYSINE {Tlaf) LYSINE (Avail) Mf IlONINE METz-1. +CYSINE ARCININE GLYCINE ISOLIUC1NE r,% LEUCINE THIREONINE TRYPTO PIHAN IIIS1flDINE I% PHENYLALANiNE PHENYLAi TYROSINE SERINE VALINE F AT1Y ACIDS LINOLEIC ACID LINOLENIC ACID w-3 2RPA UIA 2. FORMULA PER TONNE PQRCOME GA* PIC WEANER 002 PORCOMEC;A' BASE SP VITAMIN PREnMIX PV 002 MINERAL PREMIX P3M 002 AMINO ACID PREMIX PAA 002 CHOLINE CI-ILORIDE 60% USAGE 150 KG PER TONNE kg 970.80 2.50 10.00 10.00 97.080 0,250 2.000 1.000 0.670 100.000 6.70 1000.00 OF PIG WEAER DIEiT 002.

COMS ID No: SOMI-01141828 Reeeived by IP Australia: lime (Ktm) 22:52 Date 2005-02-28 2e/82/2085 21:48 +61-2-95522894 WALSH AND AS9XIATES PAGE 36/63 W0 00149889 PCTIAIO00129 11.

2. PIG WEANER VITAMIN PREMIX PV 002 cowosnlor4iO INGREDIEN-r 00 00 VITAMIN A-C500 Vl'AMJN 1)3500 VITAMIN E.50% VTAMIN IM r[LAM1N 1'YDROCnLOIRIDE tSP IBOflAVIN 95% jr.G.

PYRIDOXINEI

SP

VITAMIN B312.SUPPLEMENT 1% NIACIN LSP CALCIUM U-PANTOD IENAJTg USP F0LIC ACID USP D-3IOTIN S UPPLEMENT 1% GRE8EN TEA POWDER VANIUALC

CRYSTALS

WH-1EAT MEAL CARRIER.

POTtNCY/ GM FORMULA 500.000 ru 5.60 grn 500,000 IU 13.40 gm 500 1U 32.80 gm 1000 mg 4.02 grn 892 mg 3.00 gm 950 mg 9.87 gn 823 mg 4.88 gm 10 mg 4.69 gm 990 mg 4 0.1 In 920 mg 34.96gm 920 mg 4.37 gm 10 mg 13.40 gm 120.00 gn 1000 mg 53.60 gm 580.07 gm 1000.00 gi

ACUIVE

1Kg PREMIX 26.800.000

LU

6,700.000 ti 26.400 IU 4.02 gmn 2.68 gn 9.38 gn 4.02 gm 46.90 ing 40.20 gif 32. 16 gm 4.02 gm 134.00 mg l0-oO gin 53.60 gin USAGE: 2.5 Kg Per Tonne Patcoiega' pig Weaner Supp n- 00.

PIG WEANER. PORCOM-GA* AND COMPLeTE FEED VTrAMIN

ADDITON

COMPOS1TION ACTVE

ACTIVE

INGREDIENT 'I-bnne P0RCOMEGA- 1Kg COMPLETE

FEE

VITAMIN A-500 67.000,000 11 10,000 fU VITAMIN 1W3-500 16,750,000 JI 2,500 wU VITAMIN 2-50%Y, 466.000 1 69.5 fu VrrAMIN IQ 10.05 gi 1.50 mg THIAMINE TWDROCHLOmIDE USP 6.70 gm i.00 Mg RIBOFLAVIN 95% F.O. 23.45 gm 3.50 mg PYRIDOXJNEo lSP 10.08 gm 1.50 Mg VITAMIN B 12-S1JPPIEENT 1% 117.25 mg 17.50 meg NIACIq LISP 100.50 gmn 15.00 mg CALCIUM LI-PAN'r*l'FIE NATE USP 67.00 gin 10.00 Mg FOLIO ACID LSP ~10.05 gm 1.50mg 1)-BIOTIN SLPPLMENw r 1% 335.00 mg 50.00 meg Cl-IOU ND- CIL)RIDE 3350.00 gm 500.00 mg GREEN TEA POWDER 300.00 gin 44.77 nig VANILUC CRYSTALS I IQ A f%^

D

W&rIv ~r 2uuo mg COMS ID No: SBM1-01141828 Received by IP Australia: lime 22:52 Date 2005-02-28 2B/02/2005 21:40 22/222685 1:40 +1-2-95522994WAHANASOITSAE3/8 WALSH AND ASSIXIATES PAGE 37/63 WO OO/49889 PrATIRO2 0 0 r- 00 PIG WI&ANEII MINERAL PREMIX PM 002

COMPOSITON

INGREDIENT

POTENCY/C

FERR-'OUS SULP'HATE, 310.0 mng (Ii- S04.1120) IZINC SULPHATrE 360.0 mng IMANGANESE SULPHATmE 280.0 Mng (Mn S04.1-120) M FORMULA 216. 125 gmn 1864110 gm 95.7 15 gmn

ACTV

/Kg PREMIX 67.000 gmn 26.800 gm flLLLflOUII vU ,(iJAk5d 6$8.8 mng 0.488 grn 0.335 gff CC)UAI' CARI3ONAITR 460.0 ing 0.728 gin 0.335 grin COPPER SULPHATE 250.0 rmg 335.000 gmn 83.750 gir SODIUM SELENIT 400.0 rmg 0.504 gm 0.201 gm L, LIMESTONH CARRIER 1000.0 rug 16.5.330 gmn 165.330 gin 1000.000 gin USAGE: 10 Kg per Tonne Porcomnega 0 Pig Weaner Supplement 002.

PIG WEANER PORCADMEGA* AND COMPLETE FEED MINERAL ADDITION COMPOSITION ACTIVE ACTTiE INGREDIENT /Tonne PORCOME.GAt 1Kg COMPLETE

FEED

ZINC SULPIIJATE -Zzi 670.00 gmi 100.500 Mg MANOANESJ SU~LPHATE-Ma 268.00 gmn 40.200 rug [Mn 504.11201 POTASSIUM IODIDE(STAB)-1 3.35 gin 0.502 ing COBALT CARBONATE-Co 3.35 gui 0.502 mg COPPER SULPHATE,--Cu 837.50 gin 125.625 mng I SODIUM SELENITE,-.ge 2.01 gfi 0.301 rng 1 COMSIJONo: SBMI-01141828 Received by IP Australia: lime (H:rn) 22:52 Date 2005-02-28 2@/02/2005 21:40 28/0/285 2:48 +1-2-95522894 WALSH AND ASSOCIATES P~ 98 PAGE 39/63 WO 00/49889 FCT/AUOO/00129 IlGLETr WEANER AMINO ACID PRE MIX r'AA 002 CC)MPOS ITION INGREDIE

NT

I-LYSJNE

dI-Mrn ION INP! '1RflPON1NE.

W1HEAT ME, AL CARRI ER

FORMULA

6700.00 gin 1340.00 gm 1340.00 gmn 620.00 gm 10000.00 gin IK9 PREMIX 670.00 gmn 134.00 gmn 134.00 gmn (JSAGE.- 1 o KG PER TONNE OF P0RCOMEGA- PIG WEANER SUPPLEME.NT.

PIG WrEANER AMINO ACID PREMIX PAA 002 AMINO ACID ADDrPONS dl. MET! JIO1NINn, /lbnne PORC0MsoA* 6700.00 gmn 1340.00 gin 1Kg COMPLETE FEED 1000.00 ing 200.00 mg

TIIREONINE

1340.00 gmn 200.00 mg 14/ COMS ID Na:SBMI-Ol 141 828 Received by IP Australia: lime 22:52 Date 2005-02-28 213/02/2005 21:40 +61-2-95522e94 WALSH AND ASSOCIATES PAGE 40/63 WO 00/4989 PCT/AUDO/00129 14.

VORCOMEGA. Z'IGtLrT WEANEI SUPPLEMENT 002 II!EOR IfCL ANALYSES

TBA

00 00 CRUDE IIBRE CItLJDE I'R(YIIN CRUDE MT 54 LYSINE (Total) LY$IN (Avail) METHIONINE MITH. CYSTuvE ARGININE

IN,

GLYCINE ISOLE [UCINrj LEJCINgt T''IREONINE TUYPTOP-IAN HISTLDINE PHENYL.ALLINc I'IJENYU.+ IYROSNE SERINE VALINE Arry ACIDS LINOLEIC ACID LINOLENIC ACID %4 w-3 EPA VITA %4 CALCIUM PHOSPIORUS (Total) 3. FORMULA PER TONNE PORCQMEOAN PIG BREEDER 003 k g PORCOMEGAS DASE Sr,

O

VrrAMIN PREMIX PV 003 2.50 MINERAL Pj~rMix PM 003 10.00 1000.00 USACIE 150 KGN PR TOEr '1 PIC BREED R DIET 003.

98.750 0.250 1.000 100.000 COMS ID No: SBMI-01141828 Received by IP Australia; Time 22:52 Date 2005-02-28 2B/02/2005 21:40 +61-2-95522994 WALSH AND ASSOCIATES PAGE 41/63 WO 00/49889 PCT/AUOO/O0llp 0 0 r- 00 ci 00 00 0o 3. IG BIREP DRR VrPAMIN PRMX PV 003 COMPOSI'1ION INOREDUl-NT POTENCy/ FVVrTr"A IN D.11500A"I A-00 00,000 IL V I AMN 4 E-501%X 500-000 IL I VrJAMINK3 500IT- TI IIAMINI I IYI)ItROCRIDE, (Sp 8g000M 'RUCIOFLAVIN 95% F.CL 950 m1 *PYRIDOXINE LISP 823 rug VITAMI N B 12-SUPPLE MENTr 1% 10 Mg NIACIN LJSP 990 'rng CALCIUM L-PANCOnIo NA7'E USp 920 mg FOLIO ACID USP 920mg D-1310IN SU'IrFq-MEN 1% 10 xng.

GREN lE A [OWDER 3!(\NIUJIC

CRYSTALS

W14HC AT MEAL CAIUUER £000 mg

ACTIVE

GM FORMULA 1Kg PREIx 1 53.60 gm 5.36 gm I 1 3 4 .00 gm l0.05 gm 4.51 gm 14.11 gm 4.88 gm 4.02 gm 54. 14 grn 29.13 gin 2.91 gm 53.60 gm 120.00 gm 13.40 gi 4968.29 gin 26.800,000

IU

2.680.000 [U 67.000 Iu 10.05 gmn 4.02 gin 13.40 gin 4.02 gi 40.20 mg 53.60 gi 26.80 gi 2.68 gin 536.00 trg 120.00 gin 1000.00 gin USAGE. 2.5 Kcg er Tonne Porcoiegat Pg Breeder Supplement.

PIG BRIr,-3D-n- PORCOMEGA0 AND COMPLETE FEED VITAMIN ADDITION COMOS

[[ION

INGReDIENT f"'VrrAMIN

A-OO

VITAMIN D3-50( ;VITAMIN IC-.50% iVITAMIN KS THIAMINTE HYDROCHLOPJDE USp RIBOFLAVIN 95% F.G.

PYRIDoXINS US VITAMIN 8 1 2 -SUPPLrEMEW 1% NIACIN USP CALCIUM d-P-3ANT0I-jjjNrATE

USP

FOLIC ACIj) USP U.5[QTl4 SLJPP>LEMErI 1% CHOLINE CHLORIDE GREEN '[EA PIOWDER VANILLIC CIYSTALS

ACTIVE

Tonne PORCOMEA.

67.000.000

IU

6,700,006 IU 167.500 11 10.05 gi 10.05 gin 33.50 gin 10.05 gu 75.00 mg 134.00 gm 67.00 gm 6.70 gin 134.00 mg 20i0.00 gin 300.00 gn 33.50 gm

ACTIVE

/Kg COMPLETE

FEED

10,000 IU 1.000 fU 25.0 If 1.50 mg 1.50 mg 5.00 mg 1.50 mg 15.00 mvg 20.00 mg 10.00- mg 1.00 mg 200.00 Meg 300.00 ng 44.77 mg 5.00 mg 161 COMS ID No: SBMI-01141828 Received by P Australia: lime 22:52 Date 2005-02-28 2e/02/2005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 42/93 WO 00/49889 PCT/AU00100129 00 00 r- 00 16.

PLOG UIEnDER MINERAL PREMIX PM 003

COMPOSITON

INGREDipNT POTENCY/cu SFEOS SULJIATE 310.0 Ing We S04-1120) I ZINC SULPIA1ili, 360.0 rug MANGANESE SULPHATE 280.0 rg (Mn 504.1120) POTSRFIM rn~nrnlrrc',a n%

K

FORMULA

216.125 gn 18 6.110 gm 95.715 gn

ACTIVE

/Kg PREMIX 67.000 g 67.000 gin 26.800 gin

I

A 0 n0 g 0.488 gi 035 g COBALT CARBONATE 460-0 Mg 0.728 gm 0.335 g COPPER SULPHATE 250.0 mg 13.400 gin 3.350 g SSDIUM SE~LENT 400. 0 Mg 0.251 g1" 0.1010 LIMESTONE CARRIER 1000.0 mg 487.183 gn 1000.000 gm USAGE: 10 Kg per Tonne Prcoiega' Pig Breeder Supplement 003.

PIC BREEDEfL P0RC0MEGA* AND COMPLTE FEED MINERAL

ADITION

in m n COMPOSION ACVE

ACTIVE

INGREDIENT' Tonne PORCOMEGAe 1 COMPLETE

FEED

$04(F e 1120) 100.500 rg ZINC SULPHATE-Zn 670.00 gm 100.500 mg MANGAEE SULPILATE-Mn 268.00 g. 40.200 (MI] S04.HZO)

M

1 POTASSIUM IODIDE(STA)z 3.35 gn 0.502 mg COB3ALT CARBONAT-C o 3.35 gi 0.502 mg COPPrEn SLLPFIALT1- Cu 33.50 g 5.000 mg SSODIUM SELENflt-Se 1.01 gin 0.150mg USAGE:- 10 Ng per Toniie Porcomega' Pig fBreeder Supplement.

17/ COMS ID No: SBMI-011141828 Received by IP Australia: rime 22:52 Date 2005-02-28 28102/2005 21:40 28/0/265 2:40 +61-2-95522894 WALSH AND ASSOCIATES PG 36 PAGE 43/63 WO OO/49899 PCT/AUOO100129 I'RCMI).7 PR REDR SUIPpLEMET 00,3 'flIEOREr1cAL ANA4ySZ TJ3A D.E. frl/g CRUD8j PRzoTE'IN

%,Y

CRUDE FAT LYSINE (Tatj,-I) LYSINE (Avail) Ml'rT.nowruE METZH* +r CYSTINE /0 ARG [NINE GLYCINE ISOUCINE THREONINEr, lXYPTopHA HISTIDrNE %6 PHENYLA~j[IN 3 P-HINmL+ TYROSINE

IX

-SERINE %6 VAL1NV, FArry

ACIDS

L(NOLrjC ACID LZNOLENJC ACID EPA CALCIUM P IOSPiOpjjs (Votaj 4- FORMULA PER TONNEg PORCOMEoAt PIGUED LCIAIJG04' PORCOM~jEGA* jA~sC Sp k VITAMIN PftEMPC PV 004 984.15 9.1 MINERAL PRltMj;X PM 004 CHOLINE CIILOIDE. (30% 2.50 10.00 3.35 0.250 1.000 0.33 100.000( UISAGID' 150 Kto PER TONS1 OF PIG BR1EER ir04 38 COMS IDNo: SBMI-01141 828 Received by IP Australia: lime 22:52 Date 2005-02-28 2e/02/2005 21:40 29/8/285 2:48 +61-2-95522894 WALSH AND ASSOCIATES PG 46 PAGE 44/63 WO 00499 F CTIAUOO/OOIZ9 PL)zi1Er-jiiz I4C.ATJ'x'~,Q lA 18.

IN PREMIX PV 004 INGREDICEN'J POTENCY/GM

FORMULA

VflAMIN A-500 VITAMIN D3-500 vrr'AMIN U- -50'Y, VITAMIN 103 THIAMINE 'ryD1IQCHLOmIDE lSP RIBOFLAVIN 95% F..

PYUIDOXINE LJsp VITAMIN 0 1 2 -SUPPLEMEWJ' 1% NIACIN

LISP

CALCIUM dl-PANT0TINATEC

LISP

FOLIC ACID Usp 1I) -1[TIN STI PI'LE MENT 1 GIZJ E NTE POWDE

R

VAWILLIC

CRYSTALS

WIIEAr ME, CARRIER 5 i0ooi u 53.o0 gm 00.000 Iii 5.36 gin .500 fU 1 34.00 gm 1000 Mg 10.05 gin 8 9 2ing 4.51 gm 950 ing 14. 11 gm B2Sin9 4.88 gm 10 mg 4 .02 gin 9 90iTng 54.14 gm 9 2 0ing 2 9.13 gm 920 mg 2 .91lgm 10 Mg .53.60 gm 220.00 gin 1000mzg 23.40 gm 496.29 gin

ACTIVE

/K9 PRE&M= I. 26.800.00o IU 2.680,000 Iii 67,000 ILI 10.05 gin 4.02 gin 13.40 gin 4 .02g8m 40.20 mng 53.60 gin 26.80 gmn 2.68 gmn 536.00 irng 120.00 gin 13.40 gmz USAGIh 2. Kg er T I orcomega' Pig Breeder. Lactating Supplement.

PIG BRE EDER LACTATING. P0RCOMEGA- AND COMPLETE FEED VITAMIN

ADDITION

COMPOSITON VITAMIN A-500 VITAMIN D3.600 VITAMIN Z-50% VITAMI1N IQ3 THI,1AMINE tIYDROCH-LQRfDE

LISP

RIBO11vIjNJ 95% F.0.

PYFUDOXINE

LISP

VITAMIN 2 1 2 -SUPPLEMLCwr 1% NIACIN LISP ICALCIUM~ dj-pAN'ITICNAmE (3SF 1'OLIC ACID LISP U BIOTtN S UPPLEMEhrNT I1% GREEN TEA POWDER VANILL1C CRYSTALS ACT7VC, 'Tonne PORCOMEGA* 67.000).000) [U 167.5030 ILI 10.05 gin 10.05 gin 33.50 gin 10.05 gin 75.QQ rug 134.00 gm 67.00 gmn 6. 70 gm 134.00 trng 300.00 gOn 33,50 gmn /Kg COMPIZITE

FEED

10.000 11.1 1.000 IlI 25.0 iLI 1.50mrg 1.50 mg 5,00mrng 1.50 rug 15.00 mecg 20.00 mug 10.00 mg 1.00)Mg 200.00 mecg 44.77 mg 5.00 mg COMS IDNo: SBMI-01141828 Received by rP Australia: Time 22:5 Date 2005-02-28 20/02/2005 21:40 22/8/285 2:48 +1-2-95522e94 WALSH AND ASSOCIATES PG 58 PAGE 4E/63 WO 0/4999 PCT/AVoafooz2p PIG oIRI&EDER LACt;ATING M4INERAL PREMUC PM 004.

COMPOS TIiON INGREDIEpNT POTENCY/GM

FORM(

FERRtOUS SLI'I-IxrC- 310.0 mg 26l WPC 804.1120; ZINC.SULI'IIArE 360.0 trng 186.11 MANGANI!E SULPHAITE 280.0 'rig 95.71 (Mn 804.820;

MLA

~5 gin 0 gin 5 gm AC=iE ,K9 PRE MI G7.000 gi 67.000 go 26.800 gn COB3ALT CARBONATE- 460.0 Mg 0.728 gm 0.335 gi COPER SULPHATE, 250.0 mug 13.400 gm, 3.350 gi SODIUM SELENIT 400.0 mng 0.25 1 gin 0.101 gr LIME~STONE CARRIER 1000.0 Mug 487.183 gm 1000.000 gin USAGE: 10 Kg pel Thiline Por-comegaa Pig Breeder Lactating Supplement.

PIG B3REEDER LACTATTnQ PORCOMEGAo AND CO)MPLEIMj FiEED MINESRvL

ADDITION

C0MPOSIlloN ACTIVE

ACTIVE

INGREDIENT /Torine PORCOMEGA* 1Kg COMPLETE

FEED

FERROUS SULPHATE..F(I- 670.00 gmi0.50m (Fe S04.1120) ZINC SULrI IATE-Znl 670.00 gin 100. 500 rug MANGANEPSE SULPHATE.-Mn 268.00 gm 40.20o mg IMn S0411201 POTASSIUM IODIDE(S'rAWjq 3.35 gmn 0,502 mug COIJALT C:ARBONATE.-Co 3.35 gin 0.502 mg COPPER SLrLPATECu 33.50 gm 5.000 rug .SODIUM SSLENITE.Se 1.01 gmn USAGE: 10 KgI per Tonne Porcomnegao Pig B3reeder Lactating Supplement, 3 COMB IDNo: SBMVI-01141828 Received by IP Australia: lime (l1:r) 22:52 Date 2005-02-28 28/02/2005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 4E/63 WO 00/49889 PCT/AUOO0129 PORCOMEIGA I'IG BREEDER LACTATING SUPPLEMENT 004 THEORI]CAL, ANALYSES TBA .J0/Kg CRUDE FIBRE CRUDE PROTEIN CRUDE FlI' LYSINE 'rotal) LYSINE (Avail) METHIONINE METH. CYSTINE ARGININE GLYCINE ISOLEUCINE LEUCINE TIIREONINE TRYlYPl'HAN HISTIDINE PHENYLALANINE PFIENYL. TYROSINE SERINE VALINE FATIY ACIDS LINOLEIC ACID LINOLENIC ACID w-3 EPA DHA CALCIUM PHOSPHORUS (Total FORMULA PER TONNE PORCOMEGA PIG GROWER 005 kg PORCOMEGA* 13ASE SP 987.50 VITAMIN PREMIX PV 005 MINERAL PREMIX PM 005 2.50 10.00 97.080 0.250 1.000 100.000 1000.00 USAGE 150 KG PER TONNE OF PIG GROWER DIET 005.

21/ COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 2B/02/2005 21:40 +61-2-95522994 WALSH AND ASSOCIATES PAGE 47/63 WO 00/49889 PCT/AUOO/oo2g PIG GROW141R V1TAM[N PREMIX PV 005 CO MPOSrI'ION I1v- 1 FVrrAMIN A-1900 VITAMIN D3J-500 VITAMIN E50% (VITAMIN T-IAMINE IITYDROC-LORRE.

USP

RIBOFLAvIN 95% F.G.

PYRIDOXINE USP VITAMIN 512-SUPPLE,,MEN] 1% NIACIN USPI I CALCIUM d-P"ANTTICTENATh

USP

FOLIC ACID JSP D-BIOTIN SUPPLEMN'N 1% GREEN TEA POWDER VANILLIC CRYSTALS WI-IAT MEAL CARRIER POThCNCyj GM 500,000 JU 500.000 lu 500 1U 1000 mg 892 mg 950 mg 823 mg 990 Mg 920 rug 920 mg 10 mg l000 mg 1000 ng

FORMULA

40.20 gn 8.04,gm 53.60 gm 2.88 gn 3.00 gn 7.05 gm 4.88 gm 2.68 gm 27.07 gin 23.30 gm 1.46 gm 13.40 gn 120.00 gin 6 .70 gn

ACTIVE

1Kg IPREMix~ 20.100.)oo i(l 4,020,000 Il 26.800 II 2.68 gm 2.68 gn 6.70 gm 2.68 gm 26,80 mg 26.80 gin 2.1.44 grn 1.34 grn 134.00 zng 120.00 gin 6.70 gm 760.40 gn 1000. 00 grn USAGE,: 2.5 Kg per Tonne Porcmega' Pig Grower Supplement 005.

PIG GR1OWERt PQRCOMEGA* AND COMPLETE FEED VITAMIN ADDON COMPOSUION CS ACTIVE ACTIVE INGREDIENbrr' VITAMIN A-500 VIAMIN D3-500 VrrAMIN E.500% VITAMIN S THIAMINE IYDROCrJJm(DE

USP

RIB3OFLaVN 95% PYRIDOXINE USP VITAMIN B12-SUppLE'riNT 1% NIACIN LJSP CALCIUM d.PAI'OT.IENATE

USP

FOLIC ACID USP D-BJ11IN SUPPrLE.M EIn 1% GREEN TEA POWDER VANILLIC CRYSTAIS 11.53C ICNVC GA 50,250.000 JU 10,050,000 lu 67,000 Ii 6.70 gmn 6.70 gm 16.75 gm 6.70 gm 07.00 mg 67.00 gn 53.60 gm 3.35 gmi 335.00 ig 300.00 gn 16.75 gm iKg COMPLETE FEED 7.538 1U 1.508 iz 10 iu 1' 00 mg 1.00 Mg 2.51 mg 1.00 mg 10.05 meg 10.05 mg 8.04 mg 0.50 mg 50.25 mog 45.00 gm 2.51 mg 22/ COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 28102/2005 21:40 28/6/285 2:40 +1-2-95522894 WALSH AND ASSOCIATES P~ 26 PAGE 48/63 WO DOJ49MRg FCT/AUOOD129 0 0 r- 00 Ni PIUG GROWER MINERAL PREcMIX PM 005 INGREDu~omr1'

POTENCY/GM

EiLRR0U$ SImuLVIAE 3 10.0 rug freS041-20) ZINC SULI'hATEf. 360.0 mng MANGANESE SULPHAE f (Mn 304.820) 200m POTASSIUM IODIDE(STAB) 68.8 Mg COBALT CARBONATE 460.0 mg COPER SH.1n-lATri 250. 0 rmg _SODIUM SE LE N11TE 400.0 rug IMMSTONE CARRUiERl 1000.0 rug

FORMULA

216.125 gmn 186.110 gmn 95.715 00a 0.488 g9n 0.728 gm 13.400 gmn 0.251 gan 487.183 gmn 1000.000 gin

ACTIVE

/K9 PREMIX 67.000 gin 67.000 gmn 26.800 gmn 0.335 gmi 0.335 gin 3.350 gin 0.101 gen 487.183 gmi USAGE. 10 Kg Per Tobnne Porczomega* Pig Grower Supplement 005g.

PIG GROWER PORCOMEGA t AND COMPLETE FE ED MINERAL ADriTION COMPOSITION ACTIVE

ACTIVE

INGRZEDICNm' ITanne PORCOMEGAO 1Kg COMPLETE FEED PE RROUS SULPHATE3rFe 670.00 girn 100.500 rug (Ft S04.8-20j ZINC SULPH-ATE -Zn 670.00 gin 100.500 Mg MANGANESE SULPHATE-Mn 268.00 gm 40.200rg (Mn 304.820) M POTASSIUM IODIDE(STAB3)-I 3.35 gin 0.502 rag COB3ALT CARBON0ATE-Co 3.35 gin 0.502 ing COPPER SULPHATEri--Cu 3 3.50 gm 5.025 tri SODIUM SELE.NrriD.Sc 101 a-~ U.ADI Mug .23/ COMS IDNo: SBM 1-01 141828 Received by IP Australia: lime (I-tm) 22:52 Date 2005-02-28 2B/022005 21:40 +61-2-95522894 WALSH AND ASSJCIATES PAGE 49/63 WO 00/49899 PCTAUOOl0129 f'ORCOME!-,GA PIG GRiOwER SUPPLE-.MENT 005.

TIIEORETCLALc, ANALYSgS ThA CIIUDE FIBRE CALCIM CRUDE PROTEIN 1%PHOSPHORUS (Total CRUDE rAT LYSIN (Total) LYSINE (Avail) MrnTI-IIONINE, METH. CYSTINE ARGZNINM GLYCINE JSOLE, UCINE,, LEUCINE THRENNE *]RyrM13 IAN I-ISTIrneu HISIrDINE PHENYLALAI~NE PHiENyL.+ IYROSINE SERINE VALINE FATY ACIDS LINOLEIC ACID LINOLENI ACID I% w-3 EPA DMLA 6. F ORMUILA PER TONNE PORC0MEGA. PIG FINISHER 006 kg PORCOME-:GAS BASS SP 7.50 987.50 vrrAMIN pREMIX pV 006 MINERAL PRE MIX PM 006 2.50 97.080 0.250 1.000 100,000 10.00 1000.00 USAGE 150 KG PER TONNE OF PIG FINISHER DIET 008.

241 COMS ID No: 5DMI1-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 28/02/2005 21:40 28/8/205 2:40 +1-2--95522894 .WALSH AND ASSOCIATESPA 5/9 PAGE 50/63 WO 00/49889 24.

PIC FINISHERZ VITAMIN PRE;MIX

PV~OO(

PCTIAU010P129

COMPOSITION

INUREDIU&T

IVITAMIN A-.500 SVITAMIN D3-500 VITAMIN C-5O% VITAMIN 1K3 TNIAMINE HYDROCHLORIDE

USP

RIBOFLAVIN 915% F.G.

PYRIDOXJNE

USP

VITAMIN fl12-SUPLu~E- mj. 1% NIACIN USP CALCIUM dP13AN7OTIIENAIIIE

USP

FOLIO ACID USP D-BIar1IN.SUPPLE MaN. 1% GREEN TEA POWDER LYANILIC

CRSL

WHEAT MEAL (CARRtE R) PQTENa/oin FORMULA 600.000 xv 26.80 gmi 500,000D zU 5.36 gm 500 Iii 53.60 grit 1000 Mg 2.68 gm 892 mg 3.00 gy 950 m9 5.64 gm 823 Mg 4.88 gm 10 Mg 1.34 gr 990 Mg 1 8.R5 gin 920 mng 20.39 gui 920 mg 1.46 gm 10mUV 13.40 gm I000 Mg 120.00 gm 1000 mg 4.02gmn 1000 mg 760.40 gmn

ACTIVE

1Kg PRE.Mix 13,4030,000

II,.

2,680.000 LU.

26.600 Tv, 2.68 gin 2.68 gin 5.36 gmn 2.68 gm 13.40 mg 18.76 gin 18. 76 gui 1.34 gmn 134.00 mg 120.00 gin 4.02 grn 4000.00 gin USAE: g pr TnnePoroinga~Finisher Supplement 006.

PIC; FINIS1HER.- PORZCOMEQA ARD COMPLETE: FEED VITAMIN

ADDITION

COMPOSITION ACTIVE

ACTIVE

INGREDIENTrl VITAMIN A.50 'VITAMIN L03-,goo VITAMIN E~-50% VflAMIN K3 THIAMINE H1YDROCHLORIDE

IJSP

FRIBOFLAVIN 95% 1K.

PYRIDOXINE

USP

*ViTAMIN DI12-SuPPupM'j' 1% NIACIN USP CALCIUM CI.PANTrYH-ENATE USp FO)LIO ACID LISP D)-BIOTIN SU)PPLEMCm 1T GRE EN TEA POWDER VANILUIC CRYSTAL91 Tonne POROMEGA* 33,500.000 Lu 6 4 700.OoiJU 67.000 [U 6.70gin 6.70 gm 13.40 gmn 6.70 gmn 33.50 mng 46.90 gin 46.90 gmi 3.35 gin 335.00 mg 300.00 gi 10.0o gin /Kg COMPLE=E

FEED

5,025 xv 1.005 L 10.05 Iv 1.01 rug 2.01 rmg 1.01 mng 5.03 Meg 7.04 mg 7.04 mng 0.50 Mg 50.00 meg 45.00 rng 1.51 Mng COMS ID No: SBMI-W 141828 Received by IP Australia: Time 22:52 Date 2005-02-28 29/02/2005 21:40 +61-2-95522894 WALSH AND ASSXIATES PAGE 51/63 WO 00/49S88 In Pa/Au 00/0012 PIG F1NSH MINCRAj PREMIX PM 006

IM

c:0M~o~j-,foN 1NGRT;'-Dlr,,NT AC7WZ.

PO'TNCYfGM

FOR--A-

FERROUS 8LT~p g PR FIc ous SS04.1120) 310.O Mg 216 212.5gin 0- ZINC S ULI 1A'AE 36o mg 1 8 6 .'lOgm 67.00 MA.NGANML- SULrulz 28. rg (M n S UL.ty s 280. o ig 95.716 g n 26.8()C POTASIUM fIODIDESTAB) 68.8 ing 0.488.m 0.33 COB3ALT CARBlONATE 460.0 mg 0.728 gn COPP R SULPHATE; 250.0 mg 13.400 gi035n SODJ UM SE LENnu .35 400.0 rg 0.25 gigm 0 l LIMESTONE~ CA~lR 00.0Mg0.0 LCA530.o m g 5. 0 gin 165. 330 1000.000 am USAGE: 10 Xg per Tonne Poromega. Mnisher Supplement 006 PG fNISJR POROMEGAm ANDCOMPLEI PEED MINERAL

ADDITION

0 gm gyn gyn 'gm 'gn gin r 'SQnIA V INGRED DIENT PERROus SULPHA-Ir..e (We SO4h2oj ZINC SUI-AC1n MANGANVESE SULPUIz'y Mn (Mn S04.H20

PO

T

ASSIUM lOIDE(SPrS_).

COHAUr CARBnONAW

.Q,

OPPER SULPA' -Cu SODI UM SELENIT-.se ACTrVE lTibrne PORcCOMEGA.

670.00 gin 670.00 gin 268.00 gin 3.35 grn 3.35 gm 3 3 .50 gn 1.01 gm ACTwg lKg COMPLETE

PE:ED

100.500 Mg 100,500 trg 40.200 mg 0.502 rug 0.502 trg 5.02B ing 0.151 Mg 26/ COMS ID No: SBMI-01141828 Received by IP Australia: ime 22:52 Date 2005-02-28

Claims (6)

1. 7. An animal feed supplement according to claim 6 wherein the oil based premix comprises a blend of the IbIlowing ingredient; Ethoxyqui- vitamin grade Crude palm oil Crude Canola oil Carrier. Aniseed China Star Rosemary oil Thyme white oil Peppermint oil Benzoic Acid Phosphoric Acid S 1
2. 8. An animal feed supplement according to claim 7 wherein the dry mix premix comprises a blend of the followirig ingredients; Vitamin E Vitamin C Citric Acid Propyl Galate Calcium Propionate Wheat Meal Carriers 9 An animal feed supplement according to claim 8, wherein the fish meal oil based premix, dry mix premix and water based green tea extract are blended in the following proportions: 2 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 2B/02/2005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 54/63 ke Fish Meal
3. 983-00 98.300 Oil based premrnix 10.00 1,000 00 Dry mix Premix 5.00 0.500 Water based infused green teaextract 200 0.200 .LQ.00W 19990 00 An animal feed supplement according to claim 9 wherein the constituents of 00 the oil based premix per tonne of a food base are blended in the following proportions- 1 Etboxyquin vitamin grade 0.400 4.00 o 2 Crude pahn oil 1.500 15.00 0 3 Aniseed China Stir 0.067 0.67 4 Rosemary oil 0.100 1.00 Thyme white oil 0.100 1.00 6 Peppermint oil 0.150 1.50 7 Benzoe Acd 0.005 0.05 8 Phosphoric Acid 81% 0.250 2.50 9 Crude Canola oil Carrier 7.428 74.28 10.000 11. An animal feed supplement according to claim 10 wherein the constituents of the drymix premix per ton of food base are blended in the following proportions; kg Vitamin E 50 0.800 16.00 11 Vitamin C 0.500 10.00 12 Citric Acid 0.500 10.00 13 Propyl Gallate 0.100 2.00 14 Calcium Proplouate 0.500 10.00 Wheat Meal Carrier ZfMJ 5200 5.000 100.00. 12, An animal feed supplement according to claim 1 I wherein the Vitamin C and Citric Acid are scavenger antioxidants. 13. An animal feed supplement according to claim 12 wherein the supplement supplies the long chain ftty acids Docosahecaenoic Acid (DHA) Docosapentaenoic acid (DPA) and Eicosapentatenoic acid (EPA). 3 COMS ID No: SSMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 28/02/2005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 55/63 14. An animal feed supplement according to cIaim 13 wherein the percentage of c feed supplement is 15% of the total diet of the animal. An animal feed supplement according to claim 15 wherein the animal 00 produce is pork, poultry meat, lamb, eggs, beef or farmed fish. 16 An animal feed supplement according to claim 5 or 15 wherein the anti o0 fagal agent is calcium propionate. r- 00 O 17. An animal feed supplement according to claim 16 wherein the fish meal is o tuna and the tuna meal, oil based premix, dry mix premix and water based green tea Sindludf the following constituents; o Tuna Meal C' Ethoxyquin vitamin grade Propyl GalIate Vitamin C Crude palm oil Crude Canola oil Carrier[. ll Aniseed China Star Rosemary oil Thyme white oil Peppermint oil Vitamin E Bezoic Acid Phosphoric Acid 81% Citric Aid Calciun propionate Water based green tea extract Wheat Meal Carrier. 18. An animal feed supplement according to claim 17 wherein the tuna meal, oil based premix, and a drymix premix are blended in the following proportions per ton of food base: kg Tuna Meal 983,000 98.300
4. 985.000 98.500 Ethoxyquin vitamin grade 0.400 0.040 Crude palm oil 1,500 0.150 Crude Canola oil Carrier 7.428 0.743 Vitamin C 0.500 0.050 Propyl Gallate 0.100 0.010 Aniseed China Star 0.067 0.007 4 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 28/02/2005 21:48 +61-2-95522894 WALSH AND ASSOCIATES PAGE 56/63 O O Rosemary oil 0.100 0.010 C) Thyme white oil 0.100 0.010 Peppermint oil 0.150 0.015 Vitamin E 50 0.800 0.080 SBeazoic Acid 0.005 0.001 Phosphoric Acid 81% 0.250 0.025 Citric Acid 0.500 0.050 SCalcium Propionate 0.500 0.050 Water based green tea 00 extract 2.00 0.200 Wheat Meal Carrier 2go60i 0 0 CI 19. An animal fe)d supplement according to claim 18 wherein the supplement further comprises the following constituent proportions; Vanillic Crystals 0.013 A method of feeding animals for use as food produce for human consumption using a fish meal based feed supplement such that the food produce from said animals has a maximised level of long chain omega 3 ftty acids yet is free from taint; wherein the method comprises the steps of a) selecting a fish meal source of omega 3 long chain fatty acids provided by the fish tmal for inclusion in the diet of the animal; c) selecting at least one synthetic antioxidant; d) selecting at least one naturally ocurring antioxidant c) selecting an antibacterial agent f) selecting anti mould I anti fungal agent; and g) selecting an anti chemical activity agent; h) selecting a percentage of the feed supplement greater than 5% of the total dietary intake of the animal; wherein, the omega 3 long chain fatty acids are provided at a level which maximises the nutritional value of food produce from said animal but without taint of said food produce. 21 A method according to claim 20 comprising the further step of selecting the at least one synthetic antioxidant from one or a combination of the following: TBHQ (bba or bht) COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 28/02/2005 21:48 +51-2-95522894 WALSH AND ASSOCIATES PAGE 57/63 0 Ethoxyquin vitamin grade Propyl Gollate Vitamin C (ascorbic acid) Crude palm oil 00 Crude Canola oil 22 A method according to claim 20 comprising the further step of 00 selecting the at least one naturally occurring antioxidant from one or a 00 combination of the following: SVitamin E Carotenoids Vitamin c o Rosemary oil Ci Thyme white oil Peppermiat oil Jasmine tea Sodium Selenite 23 A method according to claim 22 comprising the further step of selecting the antibacterial agent from one or a combination of the following: Potassium Sorbate food acid Citric Acid food acid Benroic Acid food preservative Phosphoric acid 24 A method according to claim 23 comprising the further step of selecting the auti chemical agent from one or a combination of the following: Phosphoric Acid Buffer Modifier Potassium Sorbate pH modifier Citric Acid Ph modifier A method according to claim 24 comprising the further step of fotming an oil based premix by blending the following constituents: Etoxyquin vitamin grade Cnrude palm oil Crade Canola oil Carrier. Aniseed China Star 6 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 2B/02/2005 21: 40 +61-2-95522894 WALSH AND) ASSOCIATES Rosemary oil Thyme white oil C) Pempcnnirdt oil Remzit Acid 00 Phouphoric Acid 81 Ni 26 A method according to claim 24 compd sing the further step of 00 r- ~forming a dry mix. prem ix from the following ingredients;P 00 o Vitamin o Vitamin C N Citric Acid o Prowyl Galhlte o Calcium ?ropionata Ci Wheat Meal Carriers 27 A method according to claim 26 comprising the fujrther suep of: a) talong the fish meal, b) takng theaoil based premix, a) taking the dry mix premix, and d) taksng at water based green tea exftcts. blending constituents a) d) together. 28 A method according to claimn 27 comprising the fintier stop of mixing the fla~b meal, oil based premix, dry mix premix and water based grccnr tea extract in the following proportions: Fish Meal 983.00 98,300 Oil based premix 10.00 1.000 Dry mix Fremix 5.00 0.500 Water based infused green tea extrac 2.00 92QQ0 100000 00-QQQ 29. A method according to claim 28 comprising the step of blending the oil based premix per tonne of a food base in the following proportions- kg I Ethoxyquin vitamin grade 0.400 4.00 2 Crude palm oil 1.500 15.00 3 Aniseed China Star 0.067 0.67 4 Roemalry oil 0.1010 1.00 flyme white oil 0.200 1.00 7 PAGE 56/63 C-OMS ID No: SBMI-O1 141828 Received by II' Austraia: Time 22:52 Date 2CO5-02-28 2(3/022005 21: 40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 59/63 0 0 6 Peppermint oil 0.150 1.50 7 Bezoic Acid 0.005 0.05 S. 8 Phosphoric Acid 81% 0.250 2.50 9 Crude Canola oil Carrier 7.428 74.28 00 Nc-I 100.00 00 0- 30. A method according to claim 29 comprising the step of blending the 00 drymix premix per ton of food base in the following proportions- 0 Skg o 10 Vitamin E 50 0.800 16.00 0 11 Vitamin C 0.500 10.00 CN 12 Citric Acid 0.500 10.00 13 Propyl Gallate 0.100 2.00 14 Calcium Propionate 0,500 10.00 Wheat Meal Carrier 2.00 52.00 5.000 IN(M. 31 A method of preparing a feed supplement comprising the steps of; a) selecting fish meal as a source of omega 3 long chain fatty acids for inclusion in the diet of an animal; b) preparing a dry mix premix and an oil based premix; c) blending the fish meal, the oil based premix, the dry mix premix and a water basJe green tea extract, d) blending the constituents in predetermined proportions of the supplement; e) selecting additives for the supplement appropriate to the stage of development of the animal to which the supplement is fed, f) blending the additives with the fish meal, dry mix premix, oil based premix and water based green tea extract; c) feeding said anima Is with the supplement; wherein the supplement is within the range of 5%-20% of the animal's total diet 8 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 2B/022005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 60/63 00 0c 32. A method of feeding animals using a fish meal based supplement which includes a dry mix premix, an oil based premix and a water based green tea extract wherein the supplement it at a level within the range of 10%-20% of the animals' total 00 diet wherein the supplement includes the following active ingredients; 0- 00 Tuna Mcad oEthoxyquin vitamin grade Crude palm oil SRosemary oil Thyme white oil O Peppermint oil Benzoic Acid Phosphoric Acid 81% Crude Canola oil Carrier[[.J] Vitamin E Vitamin C Citric Acid Propyl Gallate wherein the method comprises the following steps: a) blending the constituents in predetermined proportions of the supplement; b) selecting additives for Ihe supplement for forming a feed supplement appropriate to the stage of development of the animal to which the supplement is fed, c) blending the additives with the constituents; d) feeding said animals with the supplement such that food produce from said animals has a maximised level of long chain omega 3 fatty acids yet is free from taint 33. A method iccordingto claim 32 wherein the method comprises the further step prior to or after blending of the dry mix and fish meal of: a) preparing the ingredients of said oil based premix according to the following mixing sequence; Crude Canola Oil Crude Palmn Oil Phosphoric Acid 81% 9 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 2B/022005 21: 40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 61/63 O O Benzoic Acid Ethoxyquin Vitamin Grade SAniseed China Star Rosemary Oil 0 0 Thyme White Oil Peppermint Oil r- b) high speed mixing of said ingredients to create a homogeneous stable emulsion. 00 o 34. A method acording to claim 33 wherein the method includes the step prior to steps a) and b) of claim 33, preparing the ingredients according to the following steps: 0 O i) heating to above 50 degrees C to liquefy the Crude palm oil; ii) heating to above 22 degrees C to liquefy the Aniseed china star; and iii) heating to above 20 degrees C to liquefy the Crude Canola Oil. A method according to claim 34 comprising the further step prior to or after blending of the oil emulsion and fish meal of; a) preparing the dry mix premix by combining the following ingredient sequence: Wheat Meal Vitamin Vitamin C Citric Acid Propyl Gallate Calcium Propionate Green Tea Powder Vanillic Cystals and b) mixing the dry mix with the oil based premix and fish meal. 36. A method according to claim 35 wherein the Oil based premix is applied by fine spray to the Fish Tuna meal; Aqueous Extraction is applied by fine spray to the Tuna meal; wherein the dry mix is added to the Tuna meal followed by mixing the whole to produce a homogeneous blend. COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 2B/022005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 62/63 0 0 37. A method according to claim 36 wherein nutritional premixes supplying vitamin and mineral requirements of particular species and stage of life Scycle/development may be included in the food supplement to satisfy the nutritional completeness ofa selected supplement 38. A method according to claim 37 wherein, the feed supplement provides a supply of long chain fatty acids [such as DRA, DPA and EPAI]. 00 39. A method according to claim 38 wherein, the feed supplement comprises 00 15% of the dietary intake of the animal. 0 o 40. An animal feed supplement for feeding to animals to maximise the level of ci long chain omega 3 fatty acids in an animal produce and without taint of the produce, O wherein the feed supplement comprises a blend of tuna meal, an oil based premix, and a O dry premix blended in the following proportions: kg Tuna Meal 985.00 98.500 Oil based premix 10.00 1.000 Dry mix Premix 5.00 0.500
5. 1000.00 100.000 41. An animal feed supplement according to claim 40, wherein the tuna meal comprises 8-20% of the total dietary intake of the animal. 42. An animal feed supplement according to claim 40, wherein the fish meal comprises 5-20% of the total dietary intake of the animal, 43. An animal feed supplement according to claim 40, wherein the feed supplement comprises an additional ingredient selected from the group consisting of ethoxyquin, benzoic acid, phosphoric acid, and popyl gallate. 44. An animal feed supplement for inclusion in the diet of an animal comprising: fish meal, an oil based premix; a dry mix premix; nod a water-based green tea extract, 11 COMS ID No: SBMI-01141828 Received by IP Australia: Time 22:52 Date 2005-02-28 28/02/2005 21:40 +61-2-95522894 WALSH AND ASSOCIATES PAGE 53/63 0 0 cI wherein the fish meal comprises 5-20% ofthe total dietary intake ofthe animal, and wherein food produce from the animal is free from taint and is selected from the group consisting of pork, poultry meat lamb, eggs, and beef 00 44. An animal feed supplement which includes fish meal as a source of omega 3 long chain fatty acids and which is greater than 5% of the total dietary intake of an 00 animal wherein the supplement includes the following composition of ingredients; 00 i) a food base comprising fish meal, an oil based premix and a dry mix; 0 ii) a vitamin premix; V) iii) a mineral premix; o iv) an amino acid premix; and o v) choline chloride. An animal feed supplement according to claim 44 wherein ingredient i) is a supplement base and ingredients ii)-v) are nutritional additives. 46. A feed supplement according to claim 45 wherein the supplement is blended according to the following proportions: PORCOMEGA*BASE-SP VrrAMIN PREMIX PV 001 MINERAL PREMIX PM 001 AMINOACIDPREMIX PAA OO1 CHOLNE CHLORIDE 60% 970.80 2.50 10.00 10.00 6.70 1000.00 97.080 0.250 1.000 1.000 0.670 I0.M&, 47. A supplement formula according to claim 46 wherein the vitamin premix is prepared according to the following composition; IEflREDENI VITAMIN A-500 VrrAMN D3-500 VITAyIlN E-50/o VITAMIN K3 THIAMINE3 HYDROCHLORIDE USP RIBOFLAVtN 95% F. G. PYRIDOXINE USP VITAMIN B12- EITENCYGM 500,000 U 500,000 1W 500 IU 1000 mg 892mg 9 50mig 823 mg ACVE EDBMIA 'Kg EREME 53.60gm 26,800,000 IU 13.40 gm 6,700,000 II 52.80 gm 26,400 IU 4.02 gm 4.02 gm 4-51 gm 11.28gm 6.51 gm 4.02 gm 10. 7 2gm 5.36gm COMS ID No: SBMI-01141828 Received by JP Australia: Time 22:52 Date 2005-02-28 2B/02/2005 22:04 22/0/265 2:84 +61-2-95522994 WALSH AND ASSOCIATES PG 41 PAGE 04112 SUPPLENMN 1% 10mg; 5.36 gri 53.60nig .)NI1ACIN LISP 990mg 54.14gm 53.60mg CALCIUMd- 00 PANTOTHENATE USP 920mg 34.96gm 32.16gm FOU1C ACfI lSP 920 mag 4.37 gui 4.02 gmn D-BIOTIN SUPPLEMENT 1% TOMg Z1.44 gmn 214.40mg 00VANILUC CRYSTALS I1000mg 53.60 gui 5S. 6 Ogin 00 WHEAT MEAL CARRIER 690L01 0 10000S 48. A supplemetnt formula according toi claim 47 wherein t.e supplement base 0 and complete feed vitamin addition are blended to rovidle the following composition: CcViMLN ACTIVE IN-CREDIMN l-Qm PORCONMGA COMPLETES FEED VITAMN A-5OC 67,000,000 LU 10,000 Iri VITAMIlN D3-500 16 ,750,000 LU 2,500 lu VrTAMIN R-50% 466,000 W 69.5 IU V1TAMINK3 10.05 ru 1.50mg THAMINE HYDROCHLORIDE LISP I 0.05 gin 1.50mg RIBOFLAVIN 95% F.G. 26.80 gmi 4.00mg PYRIDOXINE LISP 13.40 gmn 2.00 mug VITAhiN B1Z-SUPPLEMENT 1% 134.00mg 20.00 mog NIACIN LISP 134.00 gmi 20.00 tug CALCIUM d-PANTOflIENATE- LSP 80.40 gm 12.00mg FOLICACIDUSP 10,052M 1.50mg D-BIOTIN SUPPLEMENqT 1% 5 56,O00ng 80.00 mCg CHOLINE CHLOIDE 402.00 gui 600.00 mng VANTLLIC CRYSTALS 134.00 gri 20-00mtg 49. A supplement formula according to claim 48 wherein the mineral premix is prepaed. according the following composition: C0.b=WQQ ACTV NQCLGM tQBMUI /K-P& FERROUS SULPHATE 310.0mg 21 6.125 gm. 67 .OO0gin (Fe, 504,H20) Z1NCSULPHATE 360.0mg 186.110Ogm 67.000gm MANGANESE 280.0mg 95.715 gui 26 ,SO0gm, SULPHATE (Mn S043*20) POTASSIUM IODIDE 68.8 mg 0.48$ gui 0.33 5 gui (STAB0) 13 COMS ID No: SSM -01 141830 Received by IP Australia: ime (ltm) 23:05 Date 2005-02-28 29/02/2005 22:04 +61-2-95522894 WALSH AND ASSOCIATES PAGE 05/18 COBALT CARBONATE COPPER SULPHATE SODIUM SELENITE IMESTONE CARRIER 460.0 mg 250.0mg 400.0 mg 10OO.mg 0.728gm 335.000gm 0.504 gm 165.330 mi 1000,000 ff 0,335 gm 33.750 gm 0.201 g 165.3308M 00 00 A supplement formula according to claim 49 wherein the supplement food base and complete feed inineral addition are blended to provide the following composition; COVWOSUI& FERROUS SULPHATE-Fe ACflYL Mn! PORCONEG 670.00 gmn ACTIVE /s COM-- EE 100.500 mg (Fe S04.H20) ZINC SULPHATE-Zn 670.00&m MANGANESE SUPHAT--Mi 268.00 gm (Mn 504.1-120) POTkMlLjMIODIDE(STA3)-4 3.35 gn COBALT CARBONAT6-Co 3.35 gm COPPER SULPHATE4:C 837.50 gin SODIUM SELiNITE-Se 2.01 gm 100.500mg 40.200 mg 0.502mg 0.502 rug 125.625 mg 0.301 mg 51. A supplement formula according to claim 50 wherein the supplement food base and amino acid premnix is prepared according to the following composition: ELLSAT ER EW &DZIQ ACID PBEkI2 RAA 001 1 -LYSINE dl-M[EflOfNTNE THIREONINE WHEAT MEAL CARRIER FQBMIA dIi
6. 6700.00 gm 670.00 gi 1340.00 gin 134.00 gn 1340.00 gm 1 34 ,00 gm 620.00w I00Q0An 52. A supplemmnt formula according to claim 51 wherein the supplement base and amino avid additions ar blended to provide the following composition. AM=Q AM ADD I0NS a=hnf EQCEGA* KQ CQDVI1E FEED I-LYShNE dI-METHBONmqE THREONINE 6700.00 gu 134.O0gtm 1340.00 gm 1000-00 mg 200.00mg 200 .00 mg COMS ID No: SBM 1-01141830 Received by IP Australia: Time 23:05 Date 2005-02-28 21/02/2005 22:04 +61-2-95522894 WALSH AND ASSOCIATES PAGE 06/18 53. A supplement formula according to claim 52 wherein the formula is fed to piglets as a starter. 54. A supplement formula according to claim 53 wherein the supplement is blended according to the following proportions: PORCOMEGA* BASE SP VrrTAMN PREMIX PV 002 MINERAL PREMIX PV 002 AMINO ACID PREMIX PAA 002 CHOLINE CHLORIDE 60% kg 970.80 2.50 10.00 10.00 .100.00 ".7 97.080 0.250 1.000 1.000 0,670 I)QO USAGE:- 150 KG PER TONNE OF PIG WEANER DIET 002. A supplement formula according to claim 54 wherein the vitamin premix is prepared according to this following composition; C£WMPOSIION ACUTW INGREDIENT POTENCYGM FOMULA Kg PREMIX VITAMIN A-500 500,000 IU 53.60 gm 26,800,000 R VITAMINTI-3-500 500,000 IU 13.40 gmin 6,700,000 1U VITAMIN E-50% 500 It 32.80 gmn 26,400 1U VITAMINK3 1,000mg 4.02gm 4.02 gui THIAMINE 892mg 3.00 gm 268 gm HYDROCHLORIDE USP RIBOFLAVIN 95% E.G; 950mg 9.87gm 9.38 gm PYRIDOXINE USP 823 mg 4.88 gm 4.02 gm VITAMIN B12- SUPPLKMENT 1% 10mg 4.69 gm 46.90mg NIACIN USP 990 mg 40.61 gmn 40.20 gui CALCIUM d-PANTOTHENATh USP 920mg 34.96gm 3 2 .16gm FOLIC ACID USP 920 mg 4.37 gmn 4.02 gm D-BOTIN SUPPLn4aN 1% 1Omg 13.40 gm 1 34 .00mg VANILIC CRYSTALS 1000 mg 53.60 gm 53.60 gm WHEAT MEAL CARRIER 700.07 SM 1000-.00. 56. A supplement formnnula according to claim 55 wherein the supplement base and complete feed vitamin addition are blended to provide thi following composition: U CQMRQSITI fl RAMEDSNT VrTAMIN A-SOD ACTIVE ACTIYE on PORCQOMEMiA* /Kg CQMPLET 67,000,000 L 10,000 IU COMS ID No: SBMI-01141830 Received by IP Australia: Time 23:05 Date 2005-02-28 28/02/2005 22:04 +1-2-95522894 WALSH AND ASSOCIATES1 PAGE 07/le VITAMIN D3-500 VITTAMIN E-40% VITAMNK3 flHAMXNE WYDROCELORIDE USP RIBOFLAVIN 95% F.G. PYRIDOXINE USP VITAMIN B12- SUPPLEMENT 1% NIACIN USP CALCIUM d-PANTOTIHENATE USP FOLIC ACID USP D-BIOT1N SUPPLEMENT 1% CHOLINE CHLORIDE VANIUJLC CRYSTALS 16,750,000 LU 466,000 1U 10.05gm 6.70 gm 23.45 gin 10.05 gra 117.25mg 100.50 gm 67-00 gm 10. (5 gin 335.00 g 3350.00gm 13 4 .00 gm 2,500 IU 69.5 1U 1.50mg 1.00mg 3.50 mg 1.50mg 17.50 mcg 15.0mg 10.00 mg 1.50rng 50.00 mcg 500.00 mg 20.00mg 57. A supplement formula according to claim 56 wherein the mineral premix is pispared according the the fllowing composition: COMPOSITION ACTWL FITT EMNCY/GM EQBMULA fS PREMIX FERROUS SULPHATE 310.0mg 216.125 gi 67.000 gm (Fe S04.1O) ZINC SULPHATE 360.mg MANGANESE SULPHATE 280A0mg S04.1120) POTASSIUM IODEDF(STAB) COBALT CARBONATE COPPER SULPHATE SODIUM SELENqrE LIMESTONE CARRIER 68- mg 460.0 nig 250.0mg 400.0 mg 100.0mg 196.110 gm 6 7.000gm 95.715 gn 26.800 gi 0.488 gin 0.335 gm 0.728 gin 0.335 gn 33 5 00 ngm 83 .750gm 0.504 gm 0.201 gui 1652330 m 165.330 gin 10-00.000 m 58. A supplement formula acvvrding to claim 57 wherein the supplement fod base and complee 6ied mineal addition are blended to provide the following composition; CQM 3~ITIN ACI~eACTIVt RiGRED1N[ aIax PORCQMEGA* f2K F CTh FEED FERROUS SULPHATWFe 670.00 Sm 100.500 mg (Fe 504.1420) COMS ID No: SBMI-01141830 Received by IP Australia: Time 23:05 Date 2005-02-28 21302/2005 22:04 +51-2-95522894 WALSH AND ASSOCIATES PAGE 08/18 ZINC SULPHATE-Zn MANGANESE SULPHTE-Mn (Mn S04.H20) POTASSIUM IODDE(STAB)-1 COBALT CARBONATE-Co COPPER SULPHATE-Cu SODIUM SELENITE-Sc 670.00 gm 268.00 gin 3.35 gm 3.35 gm 837.50 gm 2.01 gm 100.500mg 40.200 mg 0.502 mg 0.502 mg 125.625 mg 0.301 mg 59. A supplement formula according to claim 58 wherein the supplement food base and amino acid premix is prepared according to the following composition: COMPOSITION INGRBDIENT 1-LYSINE di-METIIIONINE THREONINE WHEAT MEAL CARRER FORMTLA 6700.00 gin 1340.00 gm 1340.00gm 620.00 gm 100U00 on 670,00 gn 134.00 gin 134.00gm A supplement formula according to claim 59 wherein the supplement base and amino acid additions are blended to provide the following composition: COMPOSION INREWIST 1-LYSNE dl-METHIONIINE THREONINE WHEAT MEAL CARRIER EQRMULA 6 70 0.o00gm 1 340.00 gm 1340.00 gm 200l 1000.00 am Uz PERE&JJ 670.00 gm 134.00 gin 134.00 gm 61. A supplement formula according to claim 60 wherein the formula is fed to piglets as a weaner, 62. An animal feed supplement formula which includes fish meal as a source of omega 3 long chain fatty acids and which is greater than 5% of the total dietary intake of an animal wherein the supplement comprises; afish meal food base a litamin premix; and a raineral premix 63. A supplement formula according to claim 62 wherein the supplement is blended according to the following proportions: Kg 17 COMS ID No: SBMI-01141830 Received by IP Australia: Time 23:05 Date 2005-02-28 2G/022005 22:04 +61-2-95522894 WALSH AND ASSOCIATES PAGE 09/18 F4PORCOMMOW* BASF, SP 987.50 98.750 00 R VICMN PRE* BE 003 2.50 0.250 MINERAL PREMIX PM 003 10L00 QQQl- 00 1000.00 100.000 0 64. A supplerrent fonnula according to claim 63 wherein the vitamin premix Ci is prepared according to the following composition; WhMOMMSDN ACflYB Th{QXEIAEMT FQTNCYLQM FORMULA ZKPREMIX VITAMIfN A-500 sooo 113 53.60 gm 26,800,000 IU VITAMIN D3-500 500,000113 5.36 gm 2,680,000 IU VITAMIN E 50% 500113 134.00 gxn 67,00010TJ VITAMIN K3 1000 Wg 10.05 gn 10.05 g THIAMNE 8 9 2mg 4.51 gin 4.02gm HYROCHLORIDE iSP RIBOFLAVIN 95% F.G. 950mg 14.11gm 13-40 gin PYRIDOXI NE 13SF 823 mg 4.88 gm 4.02 gn VITAMN BI 2- SUPPLMENT 1% 10mg 4.02 gin 40.20mg NIACIN LISP 990mg 54.14gm 53.60 gm CALCUM d PANTOThENATE US? 920mg 29.13 gin 26.80 gin POLIC ACID USP 920 ig 2.91 gin 2.6$ gin D-BIOTIN SUPLEaNT 1% 10 ing 53 6 0 g 536.00mg VANILLIC CRYSTALS 1000mg l3.40gm 13.40 gm WHEAT MEAL CARRIER 616-29 S A. supplement fornula according to claim 64 wherein th. supplement base arid complete feed 'itmin addition are bended to provide the following composition; £MEMSflQ ACTIVE AC=JXL I _NGREDIENT fonne FQCOEGA* 1& -COMPLETE FID VITAMN A-500 67,000,00013 10,000 113 VITAMIN 03-500 6,700,000 m ,Do00 IU VITAMJN E-S00% 167,500 I 25.0 IT VITAMN K3 10.05 gin 1.50mg THIAMINE 10.Ogi9 1.50Img HYDROCHJLORIDE USP is COMS ID No: SBMI-01141830 Received by IP Australia: Time 23:05 Date 2005-02-28 28/02/2005 22:04 28/8/205 2:04 +1-2-95522894 WALSH AND ASSOCIATES PG 81 PAGE 10/18 RIBOFLAVIN 95% F. G. PYRJDOXINE LISP vrrAMvN BflU- SUPPLEMENT 1% MACiN USP CALCIUM PAITOTHENATE LISP FOLIC AkCID lISP D-BIOTIN'SUPPLEMENT 1% CHOLINE CHLORIDE VANILLIC CRYSTALS 33.50 gm 10.05 gin 75,00mg 134.00gSm 67.00 gmn 6,70gSm 134.00mg 2010.00 gm 33.50 gum S .00mg 1-50mng 15.00 Mug 20.00mg 10.00 mg 1,00mg 200.00 mng 300.00 mg 5.00 mg 66. A supplement formula according to claim 65 wherein the mineral premix is prepared according the following composition: RLQ9EfIP= POTENCYM FERROUS SULPHATE 310.0mg (Fe S041E120) ZINCStJLPHATE 360.Omg MANGANESE SULPHATE 280.0 mug (Mfn 8043120) POTASSIU IDE(STAB) 68.8 mg COBALT CARBONATE 460.0 mg COPPER SULPHATE 250.0 Mg SODIUJM SELFJNITE 400.0mg LUMESTONE CARRIER 1000.0mig 2 16 .l 2 5 gm ACTVE )g PREMLX 67.000 gmn 186.110gm 67 .0O~m 95.715 gin 26.800gm 0.488 gin 0.729 gm 13.400 gin 0.25 1 gin 48-7483 orn 12QM~n 0,335 gm 0.335 gmn 3.3 0.101 gin 67. A supplernenit formula according to claim 66 wherein the supplement food base and complete Jbed mineral addition are blended to provide the following composition; -C-OPOSErLN ACUMYI WOW217S tTmso RCOME~~jGA /K~jgff flTE FEED ]FERROUS SULPHATE-Fe 670.00 gin 1 O.500mg (Pe, 504H20) ZINC SULPHATE-Znk 670.00 gin 100.500mg MANGANESE 268.00 gin 40,200 iug SULPHATE-Nm (Mn 5041120) POTASSIM IODIDE(STAB)4l 3.35 gn0.502 mg COBALT CARBONATE-Co COPPER SULPHATE-Cu SODIUM SELENITESe 3.35 gitn 33.50 ri 1.01 gin 0. 502mg 5.000 Mg 0.150mg COMS ID No: SBMI-01141830 Received by IF' Australia: lime 23:05 Date 2005-02-28 28/02/2005 22:84 +61-2-95522894 WALSH AND ASSOCIATES PAGE 11/18 68. Asupplement formula according to claim 67 wherein the formnula is fed to pigs as a breeder supplement 69. A supplement formnula according to claim 68 wherein the supplement is of the total diet of the animal. A supplement fonrmula for an animal which includes fish meal as a source of omega 3 long chain fatty acids and which is greater than 5% of the total dietary intake of te animal wherein the supplement includes the following constituents: i) a foods base including fishmeal; ii) a vitamin premix; iii) a mineral premix; and iv) choline chloride. 71. A supplement formula according to claim 70 wherein ingredient i) is a supplement base and ingredients ii)-iv) are nutritional additives. 72. A supplement according to claim 71 wherein the constituents are blended in the following proportions; PORCOMEGA* BASE SP VITAMIN PREMIX PV 004 MINERAL PREMIX PM 004 CHOLINE CHLORIDE 60% 1s 984.15 2.50 10.00 335 MQo 98.415 0.250 1.000 0.33 10oq=0 73. A supplement formula according to claim 72 wherein the vitamin premix is prepared according to the following compositionw Q£iTIPOSmON VITAMIN A-500 VITAMIN D3-S00 VITAMIN E-50% VITAMIN K3 1 000mg TMWAM~sM HYDROCHLORIDE USP PYRIDOXNE USP VITAMIN B12- SUPPEMENT 1% POTENY/M 500.000 1U 500,000 I 500 I7U 1 892mg 950ing 823 mg 10 me EORMU PREMIX 53,60 gm 26,800,000 1 5.36 gm 2680,000 IU 1 3 4.00 gm 67,000 IU 10.05 gm 1005 gm 4.51 gm 4.02 gm 14.11 n 4.88 gm 4.02 gm 13.40gm 4.02 gm 40.20 gm COMS ID No: SBMI-01141830 Received by IP Australia: Time 23:05 Date 2005-02-28 2e/02/2005 22:04 +61-2-95522894 WALSH AND ASSOCIATES PAGE 12/18 NIACIN USP 990mg CALCIUM dPANTOTIIENATE USP 920mg FOUIC ACIUD USP 920 mg D-IBIOTIN SUPPLEMENT 1% 10 Mg mE VANILLIC CRYSTAL S 1000mg WREAT MEAL CARRIER 54.14 gm 53.60 gm 29.13 gm 26.80gm 2.91 gm 2.68 gin 53 6 0Ogm 536.00 13.40 gm 61-6.29 Rin _1000.00 :In 13.40 gui 74. A supplement formula according to claim 73 wherein the supplement base and complete feed vitamin addition are blnded to provide the following composition: COMPO~lgj M IE NIQaus=PQRCQ VITAMIN A-500 67,000,000 EU VITAMIN D3-500 6,700,000 RI VITAMIN E-5C3% 167,500 U VITAMIN K(3 10.05 gn THIAMINE )O.OT gm HYDROCHLORIDE USP RIBOFLAVIN 95% FG. 33.50gm PYRIDOXINE USP 10.05 gm VITAMNBI- 2 75.00mg SUPPLEMENT 1% NIACIN USP 134.00 gu CALCIUM d- 67.00 gm PANTOTHNATE USP FOLIC ACID USP 6.70 gin D-BOTM SUPPLEMENT 1% 1 3 4 .00mg VANILLIC CRYSTALS 33.50 gm AaW= ~~QM [K £MPLBTh Thfi2i 10,000 I1 1,000 IL 25.0 IW 1.50mg 1.50 mg 5.00mg 1.50 ntg 15.0mcg 20.00mg 10.00 mg l.OOig 200.00 mcg 5.00 mg A supplement formula according to claim 74 wherein the mineral premix is prepared according the fblovwiug composition: CQNWQIfQN MMEM P9JTENCY/qG FERROUS SULPHATE 310.0mrg (PC S04.1120) ZINC SULPHATE 3 60,Omg MANGANESE SULPHATE 280.0mg (hn 04.F20) POTASSIUM IODIDE 68.8mg (STAB) COBALT CARDONAn:1 460.0 mg 2163 25 gin ACTIVR /KQPRUMP 67.000 9M l 8 6.11gm 67.000 gm 95.715 gm 26.800 gm 0.488gm 0,335gm 0.728 gm 0.335 gm COMS ID No: SSM 1-01141830 Received by 1P Australia: Time 23:05 Date 2005-02-28 2e/02/2005 22:04 22/2/885 2204 +61-2-95522094 WALSH AND ASSXCIATES PAGE 13/18 COBALT SULPHRATE SODIUM SELENM~E LIMESTONE CARRIER 250.0mg 4 00.Omg 1000.0 mg 13.400gmn 0.251 gint 437 1000.000 gin 3 3 Sgm 0.101 gm 76, A supplement frmula according to claim 75 wherein the supplement food bass and complete feed minerial addition are blended to provide the following composition, CQ&OQSZLQ-N ACTIVE INGRDIEI /onnPQRCMdEi& FERROUS SULPHATR 670.00gm (Fe 504.1120) ZINC SULPHATE-Zn 670 .O0&gm MANGANESE SULPHATE-Mu 265.00 gmn (Mn 504.112) POTASSIUJMIODIDE (STAB>.I 3.35 gin COBALT CARBONATh-Co 3.35 gmi COPPER SULPHATE-Cu 33.50 gum SODIMSELENTE-S3 1.01 rm 1 0 0 ,SO0mg 40.200 mg 0. 502 mg 0-502 mug 5.000 mg OlSO tug 77. A supplement formula according to claim 76 wherein the formula is fed to pigs as a lactating supplement 78. A supplement fornula according to claim 77 wherein the supplement is of the total diet of the animal. 79. A supplement formula for an animal which includes fish meal as a source of omrega 3 lON chain faty acids and which is geater than 5% of tbie tota dietwy intake of the animial, wherein the supplement iincludes toe following vonsdwtents: i) a fbods base includiing fsmeal; 1i) a Vitamin premi; iii) a mineral premix. An animnal feed supplement according to claim 79 wh4erein ingredient i) is a supplement base and ingredients ii) -iii) are nutritional additives. 22 COMS ID No: SOM -01141830 Received by IP Australia: rime 23:05 Date 205-02-28 2B/02/2005 22:04 28/0/285 2:64 +61-2-95522894 WALSH AND ASSOCIATES PG 41 PAGE 14118 S1L A supplement formula according to claim 80 wherein th. contituenms are blended in the following proportions; kg% IPORCQMEGA t BAs.E SP 987.50 2.50 10&00 iQ 0 97.080 0.250 I&29 100.000 82- A supplement formula accordig to claim 8 1 wherein the vitamin premix is prepared according to the following compositioN4 VITAMIN DA-500 VITAMIN E-50%A VITAMIN K(3 TfflAMINE LIYDROCfLREE USP RIBOFLAvIN 95% P.G PYRJDOXm1E USP VITANMIB12- SUPLEMENT 1% NIACIN DSP CALCIM d- PANTOflENAE DiSP FOLIC ACID lSP D-BlTOmq SUPPLEIMNT 1% VANILLIC CRYSTALS WHEAT MEAL CARRER POThNCY/GI 500.000 urs 500,000 IU 500 I1U 1000mg 892mg 950 mg 823 mag. 10mg 990 mg 920 Mig 920 mng I10mg 1000mng 40.20 gm 9.04 gm 53.60 gm 2-69 gm 3.00 gm 7.05 gi 4.88 gmn 2.68 gmi 20,100,000 LU 4,020,000 LU 26,800 LUJ 2-68 gmn 6.70 Sm 2.68 gin 2 27.07 gin 26.80 gm 2 3.3Ogm 2 l. 4 4 gm. 1.46 gm 13.40 gm 6.70 gm 1.34 gm I 3 6.70 gmn 83. A supplement fontnula. according to claim 82 wherein the supplement base and complete feed vitamnin addition arm blended to provide toe following compositioni: -Q)ADSM-N CMIAC=L IL{QED-m t ~eon -PORCOMEZGA* 1K& CO Ukf T E D VITAMIN A-500 50,250,000 lb 7,53 8 LU COMS ID No: SBMI-01 141830 Received by IP Australia: lime 23:05 Date 2005-02-28 2e/02/2005 22:04 +61-2-95522894 WALSH AND ASSOCIATE/ PAGE VITAMIN D3-500 10,050,000 11 VITAMIN E-50%/ 67,000 IU VITAMINK3 6.70gm THIAMINE HYDROCHORJE ISP 6.70 g RIBOFLAVIN 95% FC 16.75 gm PYRDOXINE SP 6.70 gn ViTAMIN B 12-SUPLEMtNT 1%67.00mg NIACIN US? 67.00 gn CALCIUM d-PANTOi1IENATE uSP 53.60gm FOLIC ACID USp 3,35 gSi t)-BIOflN SUPPLEMENT 1% 335.00 mg VANILLIC CRYSTALS 16,75 gm 1,508113 10113 l.O1mg 1.00 mg 2.51 mg 1.00 mg 10.05 Meg 10.05 rg 8.04mg 0.05 ma 50.25 mcg 2.51 mg 84. A supplerflent formula acording to claim 83 wherein the mineral premix is prepared according th- fllowing compoSition: COMPOSUON am WBNTI POTENCY/QM FQEMULA FERROUS SULPKATE 0e S420) ZINC SULPHATE MANGANESE SULPHADTE (Mm S04120) POTASSIUM IODIDWSTAB) COBALT CARBONATw COPPER SULPHATE SODIUM SELENITE LINESTONE CARRIER 310.Oig 2 1 6 12 5 gm 3 60.Oig 280.0 mg 68,8 mg 4 6 0 mg 2 5 0.omg 400.0mg 1000.mg 186.110 gm 95.715 gm 0.488 gm 0728 gm 13.400 Sm 0.25 1 gm 487.183 pm IQQL.0g0 m ACTIVE /XAc PRED 67.000 grn 67.000 gm 26-800 gm 0.335 gm 0.335 gin 3.350 gm 0.101 gi 487.183 gm A supplement fonnula according to claim 84 wherein the supplement food base and complete feed mineral addition are blended to provide the following composition; INSR~mfiNI I FNG ?MNepT -Tonne PQS& A* FERROUS SULPHATEF (Fe 804120) ZINC SULPHATE-Zn MANGANESE SULPHAT-M 41 f 670.00 gi 670.00 r" 268.00 gm M&O CMPLEMh FEED 100 500mg 100-500 mg 4 0,200 mg COMS ID No: SBMI-01141830 Received by IP Australia: ime 23:05 Date 2005-02-28 20/02/2005 22:04 +61-2-95522894 WALSH AND ASSOCIATES PAGE 16/18 0 0 (MN S04.20) 0) POTASSIUM TODIDE(STAB)-I 3.35 gm 0.502 mg 00 COBALT CARBONATE-Co 3.35 gm 0.502mg C COPPER SULPHATE-Cu 33.50 gm 5.025 mg SODUM SELENITE-Se 1.01 gm 0.15 1 mg 00 86. A supplement formula according to claim 85 wherein the fbrmula is fed to pigs as a grower supplement 00 0 0 87. A supplement fonnula according to claim 86 wherein the supplement is 0 15% of the total diet of the animal. 0 88. A supplement formula for an animal which includes fish meal as a source of omega 3 long chain fatty acids and which is greater than 5% of the total dietary intake of the animal wherein th supplement includes the folowing constituents: i) a foods base including fishmeal; ii) a vitamin premix; and iii) a mineral premix. 89. A supplement formula according to claim 88 wherein ingredient i) is a supplement base and ingredients ii)- iii) are nutritional additives. A supplement according to claim 89 wherein the constituents are blended in the following proportions; kg PORCOMEGA* BASE sP 987.50 97.0o8 VITAMN PREMIX PV 006 2.50 0250 MINERAL PREMIX PM 006 X900 MO. m. 1 0ooo 91. A supplement formula according to claim 92 wherein the vitamin premix is prepared according to the following composition; NGBIENT POTENY/Gm K PR VITAMIN A-500 500,000 WT 26.80 gin 13,400,000 I. VITAMIN 33-500 500,000 IT 5.36 gin 2,680,000 IT. VITAMIN E-50% 500 1U 53.60 gin 26,800 1U. COMS ID No: SSMI-01141830 Received by IP Australia: Time 23:05 Date 2005-02-28 2B/02/2005 22:04 +61-2-95522894 WALSH AND ASSOCIATES PAGE 1718 VITAMIN K3 1000 ig TIAMINE 892 mg HYDROC4LORIDE LSP RThOFLAVIN9S%/F. G. 950mg FYRIDOXINE USP 523 mg VITAMINBIZ- 10 mg SUPPLEMENT 1% NIACUITJSP 990mg CALCIUM d-PANTOnHENArE 920 mg USP FOLIC ACHD USP 920 mig D-BIOOTIN-SUPPLEM4ENT 1% 10mg VANILUIC CRYSTALS 1000mg WHEAT MEAL (CARRDWR)1000 mg 2.68 gin 3.00 gin 5.64gm 4.38 gm 1.34gm 2.68 gin 2.68 gin 5.36gmn 2.68 gn 13.40 mg 18.95gm 18.76gm 20.39 gm 18.76 gm 1.46 gm 1.34 gm 13.40gm 134.00mg 4.02 gm 4.02gSM. 0.40 1000.00a 92. (Withdrmwt) A supplement formula according to claim 91 wherein the supplement base and complete feed vitamin addition are blended to provide the following composition: CQMEQ MON ECTt~A2~~ ING IEN AC M~ ACT[ RjC4=11EDENT /Te BOORCOMEGA* C~ bE=2 FEED VrTAMIN A-500 VITAMNhI 13-500 VITAMIN E-50%/ WAMN K3 IHIAMNE HYDROCHLORIDE LSP RIBOFLAVIN 95% F.G. PYRIDOXIE USP VITAMINB 1 2-SUPPLEMENT 1% NIACIN USP CALCIUM d-PANrTOTIrrNAm USP POLIC ACIOD LSP p-BmwIOIN SUPPLEENr i% VANrLLIC CRYSTALS 33.500,000 IU 6,100,000 IU 67,000 IU 6.70gm 6.70 gm 13 AOgin 6.70 gm 33.50mg 46.90 gm 46.90 gin 3.35 gm 335.00mng 10.05 gm 5,025 I 1,0051U 10.05 1C 1.01 ng 1.01 mg 2.01 mg [.01 Mg 5.03 MOB 7.04 mg 7.04 mg 0.50mg 50.00 mcg 1.51 mg 93. A supplement formula according to claim 92 wherein th mineral premix is prepared according the following composition: CQMrOSmONi IflGEDII PRTQNDR&GM ACfYE EQMLA K z EEMJZ FERROUS SULPHATE (Fe 5041120) ZINC SULPHATE 310.Omg 3 6 0 -Omg 216.125 gin 1 8 6 .110 Sg 67.000 gi 67.000 gm COMS ID No: SBMI-01141830 Received by IP Australia: lime 23:05 Date 2005.02-28 28/02/2005 22:04 28/0/205 2:04 +1-2-95522894 WALSH AND ASSOCIATES PG 81 PAGE 18/18 MANGANESE SULPEATm (n 504.1B20) POTASSIUM IODIDE (STAB) COBALT CARBONATE COPPER SULPHATE SODIUM SELENrrE 4 LIMESTONE CARRIER 2 80.Oi 95.715gim 26.800gmn 68.8 mg 460.0mg 25 O.Omg 0Omg 1000.0mg 0.488 gin 0.728gSm 13,400 gnm 0.25 1gm 0.101 165,330 mmn 100000am 0-335 grn 0.33 5 gmi 31350 gmn 9Mn 165.330 gmn 94. A supplement thrinula according to claim 93 wherein the supplement food base and complete feed minerai addition, are blended to provide the following composition; COD4POSMION INGREDIEN FERROUS SULPHATE-Fe We.8041120) ZINC SULPHATE-Zna MANGANESE SULPHATE-M~n (Mn 501120) POTASSIUM IODIDE, (STAB)-! COBALT CARBONATh.-Co COPPER, SULPHATE-Cu SODIUM SE-LENITE-_Se ACTIVE- Tomn PORCOMEOCjA* IK&gCOMPLETh fBE= 670.00 gin 670-00 gmi 268,00 gm 3 3 5Sgm 3.35 gmi 33.50 gm 1.01 gin 100-500 rug 100. 500 mig 40200 mg 0.502 mig 0.502 mng 5.0 2 0.15 7 mg A supplement formula according to claim 96 wherein the formnula is fed to pigs as a finishing supplement. COMS ID No: SBMI-0114183 Received by IP Australia: Time 23:06 Date 2005-02-28