AU2004261290A1 - Apparatus and methods for applying neural stimulation to a patient - Google Patents
Apparatus and methods for applying neural stimulation to a patient Download PDFInfo
- Publication number
- AU2004261290A1 AU2004261290A1 AU2004261290A AU2004261290A AU2004261290A1 AU 2004261290 A1 AU2004261290 A1 AU 2004261290A1 AU 2004261290 A AU2004261290 A AU 2004261290A AU 2004261290 A AU2004261290 A AU 2004261290A AU 2004261290 A1 AU2004261290 A1 AU 2004261290A1
- Authority
- AU
- Australia
- Prior art keywords
- stimulation
- terminal
- polarity
- pulse generator
- patient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36082—Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
- A61N1/0529—Electrodes for brain stimulation
- A61N1/0531—Brain cortex electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
- A61N1/0529—Electrodes for brain stimulation
- A61N1/0539—Anchoring of brain electrode systems, e.g. within burr hole
Landscapes
- Health & Medical Sciences (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Developmental Disabilities (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Neurosurgery (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49227303P | 2003-08-01 | 2003-08-01 | |
| US60/492,273 | 2003-08-01 | ||
| PCT/US2004/025010 WO2005011805A2 (en) | 2003-08-01 | 2004-08-02 | Apparatus and methods for applying neural stimulation to a patient |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2004261290A1 true AU2004261290A1 (en) | 2005-02-10 |
Family
ID=34115612
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2004261290A Abandoned AU2004261290A1 (en) | 2003-08-01 | 2004-08-02 | Apparatus and methods for applying neural stimulation to a patient |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US7684866B2 (enExample) |
| EP (1) | EP1654032A2 (enExample) |
| JP (1) | JP2007501067A (enExample) |
| AU (1) | AU2004261290A1 (enExample) |
| CA (1) | CA2534363A1 (enExample) |
| WO (1) | WO2005011805A2 (enExample) |
Families Citing this family (226)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060217782A1 (en) * | 1998-10-26 | 2006-09-28 | Boveja Birinder R | Method and system for cortical stimulation to provide adjunct (ADD-ON) therapy for stroke, tinnitus and other medical disorders using implantable and external components |
| US7062330B1 (en) * | 1998-10-26 | 2006-06-13 | Boveja Birinder R | Electrical stimulation adjunct (Add-ON) therapy for urinary incontinence and urological disorders using implanted lead stimulus-receiver and an external pulse generator |
| US7010351B2 (en) * | 2000-07-13 | 2006-03-07 | Northstar Neuroscience, Inc. | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
| US7672730B2 (en) * | 2001-03-08 | 2010-03-02 | Advanced Neuromodulation Systems, Inc. | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
| US20030125786A1 (en) * | 2000-07-13 | 2003-07-03 | Gliner Bradford Evan | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
| US7831305B2 (en) * | 2001-10-15 | 2010-11-09 | Advanced Neuromodulation Systems, Inc. | Neural stimulation system and method responsive to collateral neural activity |
| US7146217B2 (en) * | 2000-07-13 | 2006-12-05 | Northstar Neuroscience, Inc. | Methods and apparatus for effectuating a change in a neural-function of a patient |
| US7236831B2 (en) | 2000-07-13 | 2007-06-26 | Northstar Neuroscience, Inc. | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
| US7024247B2 (en) | 2001-10-15 | 2006-04-04 | Northstar Neuroscience, Inc. | Systems and methods for reducing the likelihood of inducing collateral neural activity during neural stimulation threshold test procedures |
| US7305268B2 (en) * | 2000-07-13 | 2007-12-04 | Northstar Neurscience, Inc. | Systems and methods for automatically optimizing stimulus parameters and electrode configurations for neuro-stimulators |
| US7756584B2 (en) * | 2000-07-13 | 2010-07-13 | Advanced Neuromodulation Systems, Inc. | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
| US7299096B2 (en) * | 2001-03-08 | 2007-11-20 | Northstar Neuroscience, Inc. | System and method for treating Parkinson's Disease and other movement disorders |
| WO2003026738A1 (en) * | 2001-09-28 | 2003-04-03 | Northstar Neuroscience, Inc. | Methods and apparatus for electrically stimulating cells implanted in the nervous system |
| US7221981B2 (en) * | 2002-03-28 | 2007-05-22 | Northstar Neuroscience, Inc. | Electrode geometries for efficient neural stimulation |
| US20050075679A1 (en) * | 2002-09-30 | 2005-04-07 | Gliner Bradford E. | Methods and apparatuses for treating neurological disorders by electrically stimulating cells implanted in the nervous system |
| US7236830B2 (en) * | 2002-12-10 | 2007-06-26 | Northstar Neuroscience, Inc. | Systems and methods for enhancing or optimizing neural stimulation therapy for treating symptoms of Parkinson's disease and/or other movement disorders |
| US7302298B2 (en) * | 2002-11-27 | 2007-11-27 | Northstar Neuroscience, Inc | Methods and systems employing intracranial electrodes for neurostimulation and/or electroencephalography |
| US20050075680A1 (en) * | 2003-04-18 | 2005-04-07 | Lowry David Warren | Methods and systems for intracranial neurostimulation and/or sensing |
| US7596408B2 (en) * | 2002-12-09 | 2009-09-29 | Medtronic, Inc. | Implantable medical device with anti-infection agent |
| US6959215B2 (en) * | 2002-12-09 | 2005-10-25 | Northstar Neuroscience, Inc. | Methods for treating essential tremor |
| AU2003297761A1 (en) * | 2002-12-09 | 2004-06-30 | Northstar Neuroscience, Inc. | Methods for treating neurological language disorders |
| WO2004052453A1 (en) * | 2002-12-09 | 2004-06-24 | Medtronic, Inc. | Low-profile implantable medical device |
| US7263401B2 (en) | 2003-05-16 | 2007-08-28 | Medtronic, Inc. | Implantable medical device with a nonhermetic battery |
| US7317947B2 (en) * | 2003-05-16 | 2008-01-08 | Medtronic, Inc. | Headset recharger for cranially implantable medical devices |
| US20050003268A1 (en) * | 2003-05-16 | 2005-01-06 | Scott Erik R. | Battery housing configuration |
| US20050004637A1 (en) * | 2003-05-16 | 2005-01-06 | Ruchika Singhal | Explantation of implantable medical device |
| WO2005011805A2 (en) | 2003-08-01 | 2005-02-10 | Northstar Neuroscience, Inc. | Apparatus and methods for applying neural stimulation to a patient |
| WO2005051479A2 (en) * | 2003-11-20 | 2005-06-09 | Advanced Neuromodulation Systems, Inc. | Electrical stimulation system and method for treating tinnitus |
| EP1694403A2 (en) * | 2003-11-20 | 2006-08-30 | Advanced Neuromodulation Systems, Inc. | Electrical stimulation system, lead, and method providing reduced neuroplasticity effects |
| US20060161219A1 (en) * | 2003-11-20 | 2006-07-20 | Advanced Neuromodulation Systems, Inc. | Electrical stimulation system and method for stimulating multiple locations of target nerve tissue in the brain to treat multiple conditions in the body |
| US9050469B1 (en) | 2003-11-26 | 2015-06-09 | Flint Hills Scientific, Llc | Method and system for logging quantitative seizure information and assessing efficacy of therapy using cardiac signals |
| US7596399B2 (en) * | 2004-04-29 | 2009-09-29 | Medtronic, Inc | Implantation of implantable medical device |
| US20050245984A1 (en) * | 2004-04-30 | 2005-11-03 | Medtronic, Inc. | Implantable medical device with lubricious material |
| NL1026137C2 (nl) * | 2004-05-07 | 2005-11-08 | Vanderlande Ind Nederland | Inrichting voor het sorteren van producten. |
| CA2573763A1 (en) * | 2004-07-15 | 2006-02-23 | Northstar Neuroscience, Inc. | Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy |
| US8014870B2 (en) * | 2004-08-11 | 2011-09-06 | Seidman Michael D | Method and apparatus for the treatment of tinnitus |
| US20090105521A1 (en) * | 2004-09-13 | 2009-04-23 | Jonathan Bentwich | Systems and methods for assessing and treating medical conditions related to the central nervous system and for enhancing cognitive functions |
| US20090099623A1 (en) * | 2004-09-13 | 2009-04-16 | Neuronix Ltd. | Systems and methods for treatment of medical conditions related to the central nervous system and for enhancing cognitive functions |
| US20060058853A1 (en) * | 2004-09-13 | 2006-03-16 | Jonathan Bentwich | Integrated system and method for treating disease using cognitive-training and brain stimulation and computerized magnetic photo-electric stimulator (cmpes) |
| US7603174B2 (en) * | 2004-10-21 | 2009-10-13 | Advanced Neuromodulation Systems, Inc. | Stimulation of the amygdalohippocampal complex to treat neurological conditions |
| US7613519B2 (en) * | 2004-10-21 | 2009-11-03 | Advanced Neuromodulation Systems, Inc. | Peripheral nerve stimulation to treat auditory dysfunction |
| US9358393B1 (en) * | 2004-11-09 | 2016-06-07 | Andres M. Lozano | Stimulation methods and systems for treating an auditory dysfunction |
| US7565200B2 (en) | 2004-11-12 | 2009-07-21 | Advanced Neuromodulation Systems, Inc. | Systems and methods for selecting stimulation sites and applying treatment, including treatment of symptoms of Parkinson's disease, other movement disorders, and/or drug side effects |
| US9314633B2 (en) | 2008-01-25 | 2016-04-19 | Cyberonics, Inc. | Contingent cardio-protection for epilepsy patients |
| US8565867B2 (en) | 2005-01-28 | 2013-10-22 | Cyberonics, Inc. | Changeable electrode polarity stimulation by an implantable medical device |
| US8260426B2 (en) | 2008-01-25 | 2012-09-04 | Cyberonics, Inc. | Method, apparatus and system for bipolar charge utilization during stimulation by an implantable medical device |
| WO2006092061A1 (en) * | 2005-03-04 | 2006-09-08 | Functional Neuroscience, Inc. | Methods and apparatus for effectuating a lasting change in a neural function of a patient, including via mechanical force on neural tissue |
| US7840272B2 (en) | 2005-06-03 | 2010-11-23 | Medrelief Inc. | Methods for modulating osteochondral development using bioelectrical stimulation |
| EP1946794A1 (en) * | 2005-07-20 | 2008-07-23 | Cyberonics, Inc. | Vagus nerve stimulation by electrical signals for controlling cerebellar tremor |
| ATE480198T1 (de) * | 2005-08-02 | 2010-09-15 | Neurotherm Inc | Gerät, um zu diagnostizieren und nervenfunktionsstörung zu behandeln |
| US7734352B2 (en) * | 2005-09-19 | 2010-06-08 | Second Sight Medical Products, Inc. | Sub-threshold stimulation to precondition neurons for supra-threshold stimulation |
| US7729773B2 (en) | 2005-10-19 | 2010-06-01 | Advanced Neuromodualation Systems, Inc. | Neural stimulation and optical monitoring systems and methods |
| US8929991B2 (en) | 2005-10-19 | 2015-01-06 | Advanced Neuromodulation Systems, Inc. | Methods for establishing parameters for neural stimulation, including via performance of working memory tasks, and associated kits |
| US20070088404A1 (en) * | 2005-10-19 | 2007-04-19 | Allen Wyler | Methods and systems for improving neural functioning, including cognitive functioning and neglect disorders |
| US20070100377A1 (en) * | 2005-10-28 | 2007-05-03 | Cyberonics, Inc. | Providing multiple signal modes for a medical device |
| US7996079B2 (en) | 2006-01-24 | 2011-08-09 | Cyberonics, Inc. | Input response override for an implantable medical device |
| US7974697B2 (en) | 2006-01-26 | 2011-07-05 | Cyberonics, Inc. | Medical imaging feedback for an implantable medical device |
| US7801601B2 (en) | 2006-01-27 | 2010-09-21 | Cyberonics, Inc. | Controlling neuromodulation using stimulus modalities |
| ES2566730T3 (es) * | 2006-03-29 | 2016-04-15 | Dignity Health | Sincronización de estimulación del nervio vago con el ciclo cardíaco de un paciente |
| US8926676B2 (en) * | 2006-04-11 | 2015-01-06 | Advanced Neuromodulation Systems, Inc. | Systems and methods for applying signals, including contralesional signals, to neural populations |
| US7962220B2 (en) | 2006-04-28 | 2011-06-14 | Cyberonics, Inc. | Compensation reduction in tissue stimulation therapy |
| US7869885B2 (en) * | 2006-04-28 | 2011-01-11 | Cyberonics, Inc | Threshold optimization for tissue stimulation therapy |
| US9084901B2 (en) | 2006-04-28 | 2015-07-21 | Medtronic, Inc. | Cranial implant |
| US8116875B2 (en) | 2006-06-16 | 2012-02-14 | Neuropoint Medical, Inc. | Implantable neurostimulation systems |
| US8014866B2 (en) * | 2006-07-13 | 2011-09-06 | Cardiac Pacemakers, Inc. | Variable voltage compliance for current output generator |
| AU2007281122A1 (en) * | 2006-08-02 | 2008-02-07 | Advanced Neuromodulation Systems, Inc. | Methods for treating neurological disorders, including neuropsychiatric and neuropsychological disorders, and associated systems |
| ES2699474T3 (es) * | 2006-08-07 | 2019-02-11 | Alpha Omega Neuro Tech Ltd | Electrodos cerebrales |
| US8103341B2 (en) * | 2006-08-25 | 2012-01-24 | Cardiac Pacemakers, Inc. | System for abating neural stimulation side effects |
| US7869867B2 (en) | 2006-10-27 | 2011-01-11 | Cyberonics, Inc. | Implantable neurostimulator with refractory stimulation |
| US10925637B2 (en) * | 2010-03-11 | 2021-02-23 | Mainstay Medical Limited | Methods of implanting electrode leads for use with implantable neuromuscular electrical stimulator |
| US9072897B2 (en) | 2007-03-09 | 2015-07-07 | Mainstay Medical Limited | Systems and methods for restoring muscle function to the lumbar spine |
| ES2827186T3 (es) | 2007-03-09 | 2021-05-20 | Mainstay Medical Ltd | Sistema de estimulación eléctrica neuromuscular |
| US11679261B2 (en) | 2007-03-09 | 2023-06-20 | Mainstay Medical Limited | Systems and methods for enhancing function of spine stabilization muscles associated with a spine surgery intervention |
| US11679262B2 (en) | 2007-03-09 | 2023-06-20 | Mainstay Medical Limited | Systems and methods for restoring muscle function to the lumbar spine |
| US11331488B2 (en) | 2007-03-09 | 2022-05-17 | Mainstay Medical Limited | Systems and methods for enhancing function of spine stabilization muscles associated with a spine surgery intervention |
| US8224453B2 (en) * | 2007-03-15 | 2012-07-17 | Advanced Neuromodulation Systems, Inc. | Spinal cord stimulation to treat pain |
| US20080249591A1 (en) * | 2007-04-06 | 2008-10-09 | Northstar Neuroscience, Inc. | Controllers for implantable medical devices, and associated methods |
| US8090446B2 (en) * | 2007-04-19 | 2012-01-03 | Advanced Neuromodulation Systems, Inc. | Methods and systems for establishing neural stimulation parameters and providing neural stimulation |
| US8364273B2 (en) * | 2007-04-24 | 2013-01-29 | Dirk De Ridder | Combination of tonic and burst stimulations to treat neurological disorders |
| US7904175B2 (en) | 2007-04-26 | 2011-03-08 | Cyberonics, Inc. | Trans-esophageal vagus nerve stimulation |
| US7962214B2 (en) | 2007-04-26 | 2011-06-14 | Cyberonics, Inc. | Non-surgical device and methods for trans-esophageal vagus nerve stimulation |
| US7869884B2 (en) | 2007-04-26 | 2011-01-11 | Cyberonics, Inc. | Non-surgical device and methods for trans-esophageal vagus nerve stimulation |
| US7974701B2 (en) | 2007-04-27 | 2011-07-05 | Cyberonics, Inc. | Dosing limitation for an implantable medical device |
| US8027737B2 (en) | 2007-08-01 | 2011-09-27 | Intelect Medical, Inc. | Lead extension with input capabilities |
| US20090105786A1 (en) * | 2007-10-22 | 2009-04-23 | University Of Washington | Method and device for strengthening synaptic connections |
| JP4488057B2 (ja) * | 2007-11-09 | 2010-06-23 | セイコーエプソン株式会社 | アクティブマトリクス装置、電気光学表示装置、および電子機器 |
| US8180442B2 (en) * | 2007-12-14 | 2012-05-15 | Greatbatch Ltd. | Deriving patient activity information from sensed body electrical information |
| US8571643B2 (en) | 2010-09-16 | 2013-10-29 | Flint Hills Scientific, Llc | Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex |
| US8382667B2 (en) | 2010-10-01 | 2013-02-26 | Flint Hills Scientific, Llc | Detecting, quantifying, and/or classifying seizures using multimodal data |
| US8337404B2 (en) | 2010-10-01 | 2012-12-25 | Flint Hills Scientific, Llc | Detecting, quantifying, and/or classifying seizures using multimodal data |
| US8315686B2 (en) * | 2008-01-30 | 2012-11-20 | New York University | Cortical electrode array and method for stimulating and recording brain activity |
| US8204603B2 (en) | 2008-04-25 | 2012-06-19 | Cyberonics, Inc. | Blocking exogenous action potentials by an implantable medical device |
| US8315703B2 (en) * | 2008-04-30 | 2012-11-20 | Advanced Neuromodulation Systems, Inc. | Methods for targeting deep brain sites to treat mood and/or anxiety disorders |
| US20090281623A1 (en) * | 2008-05-12 | 2009-11-12 | Medtronic, Inc. | Customization of implantable medical devices |
| WO2010014498A1 (en) * | 2008-07-28 | 2010-02-04 | Boston Scientific Neuromodulation Corporation | System and method for increasing relative intensity between cathodes and anodes of neurostimulation system |
| US8788042B2 (en) | 2008-07-30 | 2014-07-22 | Ecole Polytechnique Federale De Lausanne (Epfl) | Apparatus and method for optimized stimulation of a neurological target |
| US8262714B2 (en) * | 2008-08-05 | 2012-09-11 | Advanced Neuromodulation Systems, Inc. | Techniques for selecting signal delivery sites and other parameters for treating depression and other neurological disorders, and associated systems and methods |
| US8457747B2 (en) * | 2008-10-20 | 2013-06-04 | Cyberonics, Inc. | Neurostimulation with signal duration determined by a cardiac cycle |
| US8417344B2 (en) | 2008-10-24 | 2013-04-09 | Cyberonics, Inc. | Dynamic cranial nerve stimulation based on brain state determination from cardiac data |
| US9393432B2 (en) | 2008-10-31 | 2016-07-19 | Medtronic, Inc. | Non-hermetic direct current interconnect |
| WO2010056580A1 (en) * | 2008-11-11 | 2010-05-20 | Boston Scientific Neuromodulation Corporation | System and method for increasing relative intensity between cathodes and anodes of neurostimulation system using pulse slicing |
| US8788064B2 (en) | 2008-11-12 | 2014-07-22 | Ecole Polytechnique Federale De Lausanne | Microfabricated neurostimulation device |
| US20100185268A1 (en) * | 2009-01-16 | 2010-07-22 | Northstar Neuroscience, Inc. | Implantable medical devices and associated systems and methods |
| US20100191304A1 (en) * | 2009-01-23 | 2010-07-29 | Scott Timothy L | Implantable Medical Device for Providing Chronic Condition Therapy and Acute Condition Therapy Using Vagus Nerve Stimulation |
| US8396558B2 (en) * | 2009-02-11 | 2013-03-12 | University Of Maryland, Baltimore | Methods for treating central pain syndrome and other pain related pathologies |
| US8239028B2 (en) * | 2009-04-24 | 2012-08-07 | Cyberonics, Inc. | Use of cardiac parameters in methods and systems for treating a chronic medical condition |
| US8827912B2 (en) | 2009-04-24 | 2014-09-09 | Cyberonics, Inc. | Methods and systems for detecting epileptic events using NNXX, optionally with nonlinear analysis parameters |
| US8046077B2 (en) * | 2009-06-05 | 2011-10-25 | Intelect Medical, Inc. | Selective neuromodulation using energy-efficient waveforms |
| US8509903B2 (en) * | 2009-06-05 | 2013-08-13 | Intelect Medical, Inc. | Neuromodulation using energy-efficient waveforms |
| US10751537B2 (en) | 2009-10-20 | 2020-08-25 | Nyxoah SA | Arced implant unit for modulation of nerves |
| US9415215B2 (en) | 2009-10-20 | 2016-08-16 | Nyxoah SA | Methods for treatment of sleep apnea |
| US10806926B2 (en) * | 2009-10-20 | 2020-10-20 | Man & Science Sa | Implantable electrical stimulator |
| US10716940B2 (en) | 2009-10-20 | 2020-07-21 | Nyxoah SA | Implant unit for modulation of small diameter nerves |
| US9409013B2 (en) | 2009-10-20 | 2016-08-09 | Nyxoah SA | Method for controlling energy delivery as a function of degree of coupling |
| US8774937B2 (en) | 2009-12-01 | 2014-07-08 | Ecole Polytechnique Federale De Lausanne | Microfabricated surface neurostimulation device and methods of making and using the same |
| US9263043B2 (en) * | 2009-12-04 | 2016-02-16 | University Of Mississippi | Stuttering inhibition method and device |
| US9421363B2 (en) | 2010-01-20 | 2016-08-23 | The Regents Of The University Of California | Systems and devices for crainial implantation of a neuromodulation device |
| BR112012020062A2 (pt) * | 2010-02-12 | 2016-05-10 | Sapiens Steering Brain Stimulation Bv | método, produto de programa de computador e sistema de controle para determinar as configurações de estimulação para uma sonda de estimulação cerebral. |
| US11786725B2 (en) | 2012-06-13 | 2023-10-17 | Mainstay Medical Limited | Systems and methods for restoring muscle function to the lumbar spine and kits for implanting the same |
| CA2792529C (en) | 2010-03-11 | 2018-06-05 | Mainstay Medical, Inc. | Modular stimulator for treatment of back pain, implantable rf ablation system and methods of use |
| US9999763B2 (en) | 2012-06-13 | 2018-06-19 | Mainstay Medical Limited | Apparatus and methods for anchoring electrode leads adjacent to nervous tissue |
| US9950159B2 (en) | 2013-10-23 | 2018-04-24 | Mainstay Medical Limited | Systems and methods for restoring muscle function to the lumbar spine and kits for implanting the same |
| US12097365B2 (en) | 2010-03-11 | 2024-09-24 | Mainstay Medical Limited | Electrical stimulator for the treatment of back pain and methods of use |
| US11684774B2 (en) | 2010-03-11 | 2023-06-27 | Mainstay Medical Limited | Electrical stimulator for treatment of back pain and methods of use |
| SG184395A1 (en) | 2010-04-01 | 2012-11-29 | Ecole Polytech | Device for interacting with neurological tissue and methods of making and using the same |
| US8649871B2 (en) | 2010-04-29 | 2014-02-11 | Cyberonics, Inc. | Validity test adaptive constraint modification for cardiac data used for detection of state changes |
| US8831732B2 (en) | 2010-04-29 | 2014-09-09 | Cyberonics, Inc. | Method, apparatus and system for validating and quantifying cardiac beat data quality |
| US8562536B2 (en) | 2010-04-29 | 2013-10-22 | Flint Hills Scientific, Llc | Algorithm for detecting a seizure from cardiac data |
| US8679009B2 (en) | 2010-06-15 | 2014-03-25 | Flint Hills Scientific, Llc | Systems approach to comorbidity assessment |
| US8641646B2 (en) | 2010-07-30 | 2014-02-04 | Cyberonics, Inc. | Seizure detection using coordinate data |
| US12383190B2 (en) | 2011-03-04 | 2025-08-12 | Flint Hills Scientific, Llc | Detecting, assessing and managing extreme seizure events |
| US8684921B2 (en) | 2010-10-01 | 2014-04-01 | Flint Hills Scientific Llc | Detecting, assessing and managing epilepsy using a multi-variate, metric-based classification analysis |
| US9504390B2 (en) | 2011-03-04 | 2016-11-29 | Globalfoundries Inc. | Detecting, assessing and managing a risk of death in epilepsy |
| US8725239B2 (en) | 2011-04-25 | 2014-05-13 | Cyberonics, Inc. | Identifying seizures using heart rate decrease |
| US9402550B2 (en) | 2011-04-29 | 2016-08-02 | Cybertronics, Inc. | Dynamic heart rate threshold for neurological event detection |
| WO2013019853A1 (en) | 2011-08-02 | 2013-02-07 | Mainstay Medical, Inc. | Apparatus for anchoring electrode leads for use with implantable neuromuscular electrical stimulator |
| EP2760533B1 (en) | 2011-09-30 | 2021-03-10 | Nyxoah SA | Apparatus for detecting a sleep disordered breathing precursor |
| US10206591B2 (en) | 2011-10-14 | 2019-02-19 | Flint Hills Scientific, Llc | Seizure detection methods, apparatus, and systems using an autoregression algorithm |
| US8630709B2 (en) | 2011-12-07 | 2014-01-14 | Cyberonics, Inc. | Computer-implemented system and method for selecting therapy profiles of electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction |
| US8577458B1 (en) | 2011-12-07 | 2013-11-05 | Cyberonics, Inc. | Implantable device for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction with leadless heart rate monitoring |
| US10188856B1 (en) | 2011-12-07 | 2019-01-29 | Cyberonics, Inc. | Implantable device for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction |
| US8918190B2 (en) | 2011-12-07 | 2014-12-23 | Cyberonics, Inc. | Implantable device for evaluating autonomic cardiovascular drive in a patient suffering from chronic cardiac dysfunction |
| US8600505B2 (en) | 2011-12-07 | 2013-12-03 | Cyberonics, Inc. | Implantable device for facilitating control of electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction |
| US8918191B2 (en) | 2011-12-07 | 2014-12-23 | Cyberonics, Inc. | Implantable device for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction with bounded titration |
| CA2858824C (en) | 2011-12-19 | 2020-05-26 | Mainstay Medical Limited | Apparatus for rehabilitating a muscle and assessing progress of rehabilitation |
| US8700150B2 (en) | 2012-01-17 | 2014-04-15 | Cyberonics, Inc. | Implantable neurostimulator for providing electrical stimulation of cervical vagus nerves for treatment of chronic cardiac dysfunction with bounded titration |
| US8571654B2 (en) | 2012-01-17 | 2013-10-29 | Cyberonics, Inc. | Vagus nerve neurostimulator with multiple patient-selectable modes for treating chronic cardiac dysfunction |
| US20130261706A1 (en) * | 2012-03-30 | 2013-10-03 | Neuropace, Inc. | Systems and methods for applying rapid sequential electrode stimulation |
| US10448839B2 (en) | 2012-04-23 | 2019-10-22 | Livanova Usa, Inc. | Methods, systems and apparatuses for detecting increased risk of sudden death |
| US10327810B2 (en) | 2016-07-05 | 2019-06-25 | Mainstay Medical Limited | Systems and methods for enhanced implantation of electrode leads between tissue layers |
| US9186501B2 (en) | 2012-06-13 | 2015-11-17 | Mainstay Medical Limited | Systems and methods for implanting electrode leads for use with implantable neuromuscular electrical stimulator |
| US10195419B2 (en) | 2012-06-13 | 2019-02-05 | Mainstay Medical Limited | Electrode leads for use with implantable neuromuscular electrical stimulator |
| US8688212B2 (en) | 2012-07-20 | 2014-04-01 | Cyberonics, Inc. | Implantable neurostimulator-implemented method for managing bradycardia through vagus nerve stimulation |
| US11253712B2 (en) | 2012-07-26 | 2022-02-22 | Nyxoah SA | Sleep disordered breathing treatment apparatus |
| US10052097B2 (en) | 2012-07-26 | 2018-08-21 | Nyxoah SA | Implant unit delivery tool |
| US9907967B2 (en) | 2012-07-26 | 2018-03-06 | Adi Mashiach | Transcutaneous power conveyance device |
| AU2013294692B2 (en) | 2012-07-26 | 2017-09-14 | Nyxoah SA | Insert tool for selectively powering an implant unit |
| US8583238B1 (en) * | 2012-10-02 | 2013-11-12 | Great Lakes Neuro Technologies Inc. | Wearable, unsupervised transcranial direct current stimulation (tDCS) device for movement disorder therapy, and method of using |
| US9452290B2 (en) | 2012-11-09 | 2016-09-27 | Cyberonics, Inc. | Implantable neurostimulator-implemented method for managing tachyarrhythmia through vagus nerve stimulation |
| US9643008B2 (en) | 2012-11-09 | 2017-05-09 | Cyberonics, Inc. | Implantable neurostimulator-implemented method for enhancing post-exercise recovery through vagus nerve stimulation |
| US8923964B2 (en) | 2012-11-09 | 2014-12-30 | Cyberonics, Inc. | Implantable neurostimulator-implemented method for enhancing heart failure patient awakening through vagus nerve stimulation |
| US10946196B2 (en) | 2012-11-16 | 2021-03-16 | Stimscience Inc. | System for variably configurable, adaptable electrode arrays and effectuating software |
| US12453510B2 (en) * | 2012-11-16 | 2025-10-28 | Stim Science Inc. | Neuromodulation method and system for sleep disorders |
| US10220211B2 (en) | 2013-01-22 | 2019-03-05 | Livanova Usa, Inc. | Methods and systems to diagnose depression |
| US8874233B2 (en) | 2013-03-05 | 2014-10-28 | The Charles Stark Draper Laboratory, Inc. | Distributed neuro-modulation system with auxiliary stimulation-recording control units |
| US9643011B2 (en) | 2013-03-14 | 2017-05-09 | Cyberonics, Inc. | Implantable neurostimulator-implemented method for managing tachyarrhythmic risk during sleep through vagus nerve stimulation |
| US9731122B2 (en) | 2013-04-29 | 2017-08-15 | Rainbow Medical Ltd. | Electroosmotic tissue treatment |
| EP3003473B1 (en) | 2013-05-30 | 2018-08-22 | Graham H. Creasey | Topical neurological stimulation |
| US11229789B2 (en) | 2013-05-30 | 2022-01-25 | Neurostim Oab, Inc. | Neuro activator with controller |
| CA2915077C (en) | 2013-06-17 | 2022-06-14 | Adi Mashiach | Dynamic modification of modulation throughout a therapy period |
| US9999773B2 (en) | 2013-10-30 | 2018-06-19 | Cyberonics, Inc. | Implantable neurostimulator-implemented method utilizing multi-modal stimulation parameters |
| US9511228B2 (en) | 2014-01-14 | 2016-12-06 | Cyberonics, Inc. | Implantable neurostimulator-implemented method for managing hypertension through renal denervation and vagus nerve stimulation |
| US9409024B2 (en) | 2014-03-25 | 2016-08-09 | Cyberonics, Inc. | Neurostimulation in a neural fulcrum zone for the treatment of chronic cardiac dysfunction |
| US9415224B2 (en) | 2014-04-25 | 2016-08-16 | Cyberonics, Inc. | Neurostimulation and recording of physiological response for the treatment of chronic cardiac dysfunction |
| US9272143B2 (en) | 2014-05-07 | 2016-03-01 | Cyberonics, Inc. | Responsive neurostimulation for the treatment of chronic cardiac dysfunction |
| US9713719B2 (en) | 2014-04-17 | 2017-07-25 | Cyberonics, Inc. | Fine resolution identification of a neural fulcrum for the treatment of chronic cardiac dysfunction |
| US9950169B2 (en) | 2014-04-25 | 2018-04-24 | Cyberonics, Inc. | Dynamic stimulation adjustment for identification of a neural fulcrum |
| CN106455985B (zh) | 2014-05-16 | 2019-09-17 | 阿莱瓦神经治疗股份有限公司 | 与神经组织相互作用的装置及其制造和使用方法 |
| US11311718B2 (en) | 2014-05-16 | 2022-04-26 | Aleva Neurotherapeutics Sa | Device for interacting with neurological tissue and methods of making and using the same |
| US9770599B2 (en) | 2014-08-12 | 2017-09-26 | Cyberonics, Inc. | Vagus nerve stimulation and subcutaneous defibrillation system |
| US9533153B2 (en) | 2014-08-12 | 2017-01-03 | Cyberonics, Inc. | Neurostimulation titration process |
| US9737716B2 (en) | 2014-08-12 | 2017-08-22 | Cyberonics, Inc. | Vagus nerve and carotid baroreceptor stimulation system |
| US9474894B2 (en) | 2014-08-27 | 2016-10-25 | Aleva Neurotherapeutics | Deep brain stimulation lead |
| US9925376B2 (en) | 2014-08-27 | 2018-03-27 | Aleva Neurotherapeutics | Treatment of autoimmune diseases with deep brain stimulation |
| US9403011B2 (en) | 2014-08-27 | 2016-08-02 | Aleva Neurotherapeutics | Leadless neurostimulator |
| US9872996B2 (en) | 2014-10-01 | 2018-01-23 | James William Phillips | System and method for transcranial current loop brain stimulation |
| US10471268B2 (en) * | 2014-10-16 | 2019-11-12 | Mainstay Medical Limited | Systems and methods for monitoring muscle rehabilitation |
| US10478612B2 (en) * | 2014-10-31 | 2019-11-19 | Avent, Inc. | Method and system for monitoring and treating a medical condition via posterior tibial nerve stimulation |
| US9504832B2 (en) | 2014-11-12 | 2016-11-29 | Cyberonics, Inc. | Neurostimulation titration process via adaptive parametric modification |
| US11077301B2 (en) | 2015-02-21 | 2021-08-03 | NeurostimOAB, Inc. | Topical nerve stimulator and sensor for bladder control |
| US9616221B2 (en) | 2015-07-08 | 2017-04-11 | Rainbow Medical Ltd. | Electrical treatment of Alzheimer's disease |
| EP3344192A4 (en) | 2015-09-04 | 2019-05-15 | The Johns Hopkins University | INTERCANUAL DEVICE WITH LOW PROFILE |
| US10155107B2 (en) | 2015-10-07 | 2018-12-18 | Medtronic, Inc. | Implantable modular electrode array assembly |
| US10898716B2 (en) | 2015-10-29 | 2021-01-26 | Rainbow Medical Ltd. | Electrical substance clearance from the brain |
| US9724515B2 (en) * | 2015-10-29 | 2017-08-08 | Rainbow Medical Ltd. | Electrical substance clearance from the brain for treatment of Alzheimer's disease |
| US9770591B2 (en) | 2015-12-29 | 2017-09-26 | Rainbow Medical Ltd. | Disc therapy |
| US11484706B2 (en) | 2015-12-29 | 2022-11-01 | Discure Technologies Ltd | Disc therapy |
| US11504038B2 (en) | 2016-02-12 | 2022-11-22 | Newton Howard | Early detection of neurodegenerative disease |
| US20200222010A1 (en) * | 2016-04-22 | 2020-07-16 | Newton Howard | System and method for deep mind analysis |
| US11957897B2 (en) * | 2016-04-22 | 2024-04-16 | Newton Howard | Biological co-processor (BCP) |
| US10912648B2 (en) | 2016-08-30 | 2021-02-09 | Longeviti Neuro Solutions Llc | Method for manufacturing a low-profile intercranial device and the low-profile intercranial device manufactured thereby |
| US10737096B1 (en) | 2016-10-25 | 2020-08-11 | Maurice M. Klee | Charge-based methods for modifying neural activity |
| US20220118258A1 (en) * | 2017-05-26 | 2022-04-21 | Newton Howard | Brain monitoring and stimulation devices and methods |
| US20210263589A1 (en) * | 2017-05-26 | 2021-08-26 | Newton Howard | Kinetic intelligent wireless implant/neurons on augmented human |
| WO2019060298A1 (en) | 2017-09-19 | 2019-03-28 | Neuroenhancement Lab, LLC | METHOD AND APPARATUS FOR NEURO-ACTIVATION |
| CN111601636A (zh) | 2017-11-07 | 2020-08-28 | Oab神经电疗科技公司 | 具有自适应电路的非侵入性神经激活器 |
| US11717686B2 (en) | 2017-12-04 | 2023-08-08 | Neuroenhancement Lab, LLC | Method and apparatus for neuroenhancement to facilitate learning and performance |
| US11478603B2 (en) | 2017-12-31 | 2022-10-25 | Neuroenhancement Lab, LLC | Method and apparatus for neuroenhancement to enhance emotional response |
| US12280219B2 (en) | 2017-12-31 | 2025-04-22 | NeuroLight, Inc. | Method and apparatus for neuroenhancement to enhance emotional response |
| US11589992B2 (en) | 2018-01-09 | 2023-02-28 | Longeviti Neuro Solutions Llc | Universal low-profile intercranial assembly |
| US10702692B2 (en) | 2018-03-02 | 2020-07-07 | Aleva Neurotherapeutics | Neurostimulation device |
| EP3765141A1 (en) | 2018-03-14 | 2021-01-20 | Rainbow Medical Ltd. | Electrical substance clearance from the brain |
| US11364361B2 (en) | 2018-04-20 | 2022-06-21 | Neuroenhancement Lab, LLC | System and method for inducing sleep by transplanting mental states |
| CN113382683A (zh) | 2018-09-14 | 2021-09-10 | 纽罗因恒思蒙特实验有限责任公司 | 改善睡眠的系统和方法 |
| JP2022538419A (ja) | 2019-06-26 | 2022-09-02 | ニューロスティム テクノロジーズ エルエルシー | 適応回路を備えた非侵襲性神経活性化装置 |
| US11446084B2 (en) | 2019-07-12 | 2022-09-20 | Neuralink Corp. | Laser drilling of pia mater |
| EP4003492B1 (en) * | 2019-07-31 | 2025-06-25 | Novocure GmbH | Applying tumor treating fields (ttfields) via electrodes embedded into skull implants |
| WO2021071871A1 (en) * | 2019-10-09 | 2021-04-15 | Trustees Of Boston University | Electrography system employing layered electrodes for improved spatial resolution |
| EP4017580A4 (en) | 2019-12-16 | 2023-09-06 | Neurostim Technologies LLC | NON-INVASIVE NERVE ACTIVATOR WITH AMPLIFIED CHARGE DISTRIBUTION |
| US12138458B2 (en) | 2020-07-13 | 2024-11-12 | EPIC Neuro, Inc. | Brain stimulation using subcranial electrode and subcutaneous electrode |
| US11571541B2 (en) | 2020-10-27 | 2023-02-07 | David Richardson Hubbard, JR. | Apparatus and methods of transcranial stimulation to adjust sensory cortical dendritic spine neck membrane potentials for altering consciousness |
| US11298530B1 (en) | 2021-05-03 | 2022-04-12 | Discure Technologies Ltd. | Synergistic therapies for intervertebral disc degeneration |
| US11344721B1 (en) | 2021-08-16 | 2022-05-31 | Rainbow Medical Ltd. | Cartilage treatment |
| US11413455B1 (en) | 2022-02-08 | 2022-08-16 | Rainbow Medical Ltd. | Electrical treatment of Alzheimer's disease |
| CN115054257A (zh) * | 2022-06-17 | 2022-09-16 | 中国科学院脑科学与智能技术卓越创新中心 | 一种用于脑部的柔性电极及其制造方法 |
| US12208267B1 (en) | 2024-04-19 | 2025-01-28 | Yossi Gross | Blood flow enhancement therapy system |
Family Cites Families (303)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2716226A (en) | 1951-06-22 | 1955-08-23 | Reiner Electronics Co Inc | Electrical solderless connector |
| US2721316A (en) | 1953-06-09 | 1955-10-18 | Joseph D Shaw | Method and means for aiding the blind |
| US3628193A (en) | 1969-02-19 | 1971-12-21 | Inst Of Medical Sciences The | Tactile image projection system |
| CH507005A (fr) * | 1969-03-26 | 1971-05-15 | Inst Medicina Farmacie | Appareil pour la neurostimulation électrique en vue de l'évacuation de la vessie urinaire neurogène |
| US3850161A (en) | 1973-04-09 | 1974-11-26 | S Liss | Method and apparatus for monitoring and counteracting excess brain electrical energy to prevent epileptic seizures and the like |
| US4019518A (en) * | 1975-08-11 | 1977-04-26 | Medtronic, Inc. | Electrical stimulation system |
| US4030509A (en) | 1975-09-30 | 1977-06-21 | Mieczyslaw Mirowski | Implantable electrodes for accomplishing ventricular defibrillation and pacing and method of electrode implantation and utilization |
| US4125116A (en) | 1977-02-14 | 1978-11-14 | The Johns Hopkins University | Human tissue stimulation electrode structure |
| US4140133A (en) * | 1977-04-26 | 1979-02-20 | Moskovsky Oblastnoi Nauchno-Issledovatelsky Institut Akusherstva I Ginekolog Ii | Device for pulse current action on central nervous system |
| CA1065969A (fr) * | 1977-09-28 | 1979-11-06 | Gratien Bouillon | Sonde cerebrale auto-bloquante |
| US4214804A (en) | 1978-09-25 | 1980-07-29 | Daig Corporation | Press fit electrical connection apparatus |
| US4431000A (en) * | 1978-11-29 | 1984-02-14 | Gatron Corporation | Transcutaneous nerve stimulator with pseusorandom pulse generator |
| US4474186A (en) | 1979-07-17 | 1984-10-02 | Georgetown University | Computerized electro-oculographic (CEOG) system with feedback control of stimuli |
| US4308868A (en) * | 1980-05-27 | 1982-01-05 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Implantable electrical device |
| US4328813A (en) | 1980-10-20 | 1982-05-11 | Medtronic, Inc. | Brain lead anchoring system |
| US4340038A (en) | 1980-12-15 | 1982-07-20 | Pacesetter Systems, Inc. | Magnetic field concentration means and method for an implanted device |
| US4390023A (en) | 1981-04-30 | 1983-06-28 | Medtronic, Inc. | Patterned electrical tissue stimulator |
| CA1215128A (en) | 1982-12-08 | 1986-12-09 | Pedro Molina-Negro | Electric nerve stimulator device |
| US4542752A (en) | 1983-04-22 | 1985-09-24 | Cordis Corporation | Implantable device having porous surface with carbon coating |
| US4844075A (en) | 1984-01-09 | 1989-07-04 | Pain Suppression Labs, Inc. | Transcranial stimulation for the treatment of cerebral palsy |
| US4607639A (en) | 1984-05-18 | 1986-08-26 | Regents Of The University Of California | Method and system for controlling bladder evacuation |
| US4590946A (en) | 1984-06-14 | 1986-05-27 | Biomed Concepts, Inc. | Surgically implantable electrode for nerve bundles |
| US4532931A (en) | 1984-06-29 | 1985-08-06 | Cardiac Pacemakers, Inc. | Pacemaker with adaptive sensing means for use with unipolar or bipolar leads |
| US4646744A (en) * | 1984-06-29 | 1987-03-03 | Zion Foundation | Method and treatment with transcranially applied electrical signals |
| CA1292285C (en) | 1985-08-21 | 1991-11-19 | Paul H. Stypulkowski | External ear canal electrode to be placed proximate the tympanic membrane and method of stimulating/recording utilizing external ear canal electrode placed proximate the tympanic membrane |
| US5054906A (en) | 1986-01-17 | 1991-10-08 | Brimfield Precision, Inc. | Indirectly illuminating ophthalmological speculum |
| US4969468A (en) | 1986-06-17 | 1990-11-13 | Alfred E. Mann Foundation For Scientific Research | Electrode array for use in connection with a living body and method of manufacture |
| US4817634A (en) * | 1987-06-18 | 1989-04-04 | Medtronic, Inc. | Epicardial patch electrode |
| US4869255A (en) | 1987-12-04 | 1989-09-26 | Ad-Tech Medical Instrument Corp. | Electrical connection device |
| US4865048A (en) | 1987-12-31 | 1989-09-12 | Eckerson Harold D | Method and apparatus for drug free neurostimulation |
| US4903702A (en) * | 1988-10-17 | 1990-02-27 | Ad-Tech Medical Instrument Corporation | Brain-contact for sensing epileptogenic foci with improved accuracy |
| US5458631A (en) | 1989-01-06 | 1995-10-17 | Xavier; Ravi | Implantable catheter with electrical pulse nerve stimulators and drug delivery system |
| US5002053A (en) * | 1989-04-21 | 1991-03-26 | University Of Arkansas | Method of and device for inducing locomotion by electrical stimulation of the spinal cord |
| DE3914662A1 (de) | 1989-05-03 | 1990-11-08 | Alt Eckhard | Vorrichtung zum uebertragen elektrischer signale zwischen einem implantierbaren medizinischen geraet und elektrisch erregbarem menschlichen gewebe |
| US5119832A (en) | 1989-07-11 | 1992-06-09 | Ravi Xavier | Epidural catheter with nerve stimulators |
| US5024226A (en) | 1989-08-17 | 1991-06-18 | Critikon, Inc. | Epidural oxygen sensor |
| US5063932A (en) | 1989-10-03 | 1991-11-12 | Mieczyslaw Mirowski | Controlled discharge defibrillation electrode |
| US5215088A (en) | 1989-11-07 | 1993-06-01 | The University Of Utah | Three-dimensional electrode device |
| US5271417A (en) | 1990-01-23 | 1993-12-21 | Cardiac Pacemakers, Inc. | Defibrillation electrode having smooth current distribution |
| US5031618A (en) | 1990-03-07 | 1991-07-16 | Medtronic, Inc. | Position-responsive neuro stimulator |
| US5044368A (en) | 1990-04-23 | 1991-09-03 | Ad-Tech Medical Instrument Corporation | Diagnostic electrode for use with magnetic resonance imaging |
| US5713926A (en) * | 1990-04-25 | 1998-02-03 | Cardiac Pacemakers, Inc. | Implantable intravenous cardiac stimulation system with pulse generator housing serving as optional additional electrode |
| US5314458A (en) | 1990-06-01 | 1994-05-24 | University Of Michigan | Single channel microstimulator |
| US5095905A (en) * | 1990-06-07 | 1992-03-17 | Medtronic, Inc. | Implantable neural electrode |
| US5092835A (en) * | 1990-07-06 | 1992-03-03 | Schurig Janet L S | Brain and nerve healing power apparatus and method |
| US5121754A (en) | 1990-08-21 | 1992-06-16 | Medtronic, Inc. | Lateral displacement percutaneously inserted epidural lead |
| US5342410A (en) | 1990-10-05 | 1994-08-30 | Eric Braverman | Apparatus and method for increasing the amplitude of P300 waves in the human brain |
| US5618531A (en) | 1990-10-19 | 1997-04-08 | New York University | Method for increasing the viability of cells which are administered to the brain or spinal cord |
| US5224491A (en) | 1991-01-07 | 1993-07-06 | Medtronic, Inc. | Implantable electrode for location within a blood vessel |
| US5269303A (en) | 1991-02-22 | 1993-12-14 | Cyberonics, Inc. | Treatment of dementia by nerve stimulation |
| US5215086A (en) | 1991-05-03 | 1993-06-01 | Cyberonics, Inc. | Therapeutic treatment of migraine symptoms by stimulation |
| US5299569A (en) * | 1991-05-03 | 1994-04-05 | Cyberonics, Inc. | Treatment of neuropsychiatric disorders by nerve stimulation |
| US5255678A (en) | 1991-06-21 | 1993-10-26 | Ecole Polytechnique | Mapping electrode balloon |
| US5750376A (en) | 1991-07-08 | 1998-05-12 | Neurospheres Holdings Ltd. | In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny |
| US5169384A (en) | 1991-08-16 | 1992-12-08 | Bosniak Stephen L | Apparatus for facilitating post-traumatic, post-surgical, and/or post-inflammatory healing of tissue |
| US5304206A (en) * | 1991-11-18 | 1994-04-19 | Cyberonics, Inc. | Activation techniques for implantable medical device |
| US5193540A (en) | 1991-12-18 | 1993-03-16 | Alfred E. Mann Foundation For Scientific Research | Structure and method of manufacture of an implantable microstimulator |
| US5358514A (en) | 1991-12-18 | 1994-10-25 | Alfred E. Mann Foundation For Scientific Research | Implantable microdevice with self-attaching electrodes |
| US5184620A (en) * | 1991-12-26 | 1993-02-09 | Marquette Electronics, Inc. | Method of using a multiple electrode pad assembly |
| US5406957A (en) * | 1992-02-05 | 1995-04-18 | Tansey; Michael A. | Electroencephalic neurofeedback apparatus for training and tracking of cognitive states |
| US5303705A (en) * | 1992-05-01 | 1994-04-19 | Nenov Valeriy I | Evoked 23NA MR imaging of sodium currents in the brain |
| US5423877A (en) | 1992-05-04 | 1995-06-13 | David C. Mackey | Method and device for acute pain management by simultaneous spinal cord electrical stimulation and drug infusion |
| US5263967B1 (en) | 1992-05-15 | 2000-12-19 | Brimfield Prec Inc | Medical instrument with dual action drive |
| US5476494A (en) | 1992-09-11 | 1995-12-19 | Massachusetts Institute Of Technology | Low pressure neural contact structure |
| US5441528A (en) | 1992-09-25 | 1995-08-15 | Symtonic, S.A. | Method and system for applying low energy emission therapy |
| US5370672A (en) | 1992-10-30 | 1994-12-06 | The Johns Hopkins University | Computer-controlled neurological stimulation system |
| US5358513A (en) | 1992-12-09 | 1994-10-25 | Medtronic, Inc. | Parameter selection and electrode placement of neuromuscular electrical stimulation apparatus |
| SE9203734D0 (sv) | 1992-12-11 | 1992-12-11 | Siemens Elema Ab | Defibrilleringssystem |
| US5537512A (en) | 1993-05-26 | 1996-07-16 | Northrop Grumman Corporation | Neural network elements |
| US5411540A (en) | 1993-06-03 | 1995-05-02 | Massachusetts Institute Of Technology | Method and apparatus for preferential neuron stimulation |
| US5593432A (en) * | 1993-06-23 | 1997-01-14 | Neuroware Therapy International, Inc. | Method for neurostimulation for pain alleviation |
| US5540736A (en) | 1993-08-02 | 1996-07-30 | Haimovich; Yechiel | Transcranial electrostimulation apparatus having two electrode pairs and independent current generators |
| US5417719A (en) | 1993-08-25 | 1995-05-23 | Medtronic, Inc. | Method of using a spinal cord stimulation lead |
| US5464446A (en) | 1993-10-12 | 1995-11-07 | Medtronic, Inc. | Brain lead anchoring system |
| US5470846A (en) | 1994-01-14 | 1995-11-28 | Sandyk; Reuven | Treatment of neurological and mental disorders |
| US5405375A (en) * | 1994-01-21 | 1995-04-11 | Incontrol, Inc. | Combined mapping, pacing, and defibrillating catheter |
| US5697975A (en) | 1994-02-09 | 1997-12-16 | The University Of Iowa Research Foundation | Human cerebral cortex neural prosthetic for tinnitus |
| US5843093A (en) | 1994-02-09 | 1998-12-01 | University Of Iowa Research Foundation | Stereotactic electrode assembly |
| US5562708A (en) | 1994-04-21 | 1996-10-08 | Medtronic, Inc. | Method and apparatus for treatment of atrial fibrillation |
| US5769778A (en) | 1994-04-22 | 1998-06-23 | Somatics, Inc. | Medical magnetic non-convulsive stimulation therapy |
| US6152143A (en) | 1994-05-09 | 2000-11-28 | Somnus Medical Technologies, Inc. | Method for treatment of air way obstructions |
| US5685313A (en) | 1994-05-31 | 1997-11-11 | Brain Monitor Ltd. | Tissue monitor |
| US5601611A (en) * | 1994-08-05 | 1997-02-11 | Ventritex, Inc. | Optical blood flow measurement apparatus and method and implantable defibrillator incorporating same |
| US5549655A (en) | 1994-09-21 | 1996-08-27 | Medtronic, Inc. | Method and apparatus for synchronized treatment of obstructive sleep apnea |
| US5540734A (en) | 1994-09-28 | 1996-07-30 | Zabara; Jacob | Cranial nerve stimulation treatments using neurocybernetic prosthesis |
| US5722401A (en) * | 1994-10-19 | 1998-03-03 | Cardiac Pathways Corporation | Endocardial mapping and/or ablation catheter probe |
| US5522864A (en) | 1994-10-25 | 1996-06-04 | Wallace; Larry B. | Apparatus and method for ocular treatment |
| US5520190A (en) | 1994-10-31 | 1996-05-28 | Ventritex, Inc. | Cardiac blood flow sensor and method |
| US6425852B1 (en) | 1994-11-28 | 2002-07-30 | Emory University | Apparatus and method for transcranial magnetic brain stimulation, including the treatment of depression and the localization and characterization of speech arrest |
| US5545186A (en) * | 1995-03-30 | 1996-08-13 | Medtronic, Inc. | Prioritized rule based method and apparatus for diagnosis and treatment of arrhythmias |
| US5885976A (en) * | 1995-05-08 | 1999-03-23 | Sandyk; Reuven | Methods useful for the treatment of neurological and mental disorders related to deficient serotonin neurotransmission and impaired pineal melatonin functions |
| US5591216A (en) * | 1995-05-19 | 1997-01-07 | Medtronic, Inc. | Method for treatment of sleep apnea by electrical stimulation |
| US5772591A (en) | 1995-06-06 | 1998-06-30 | Patient Comfort, Inc. | Electrode assembly for signaling a monitor |
| US6111911A (en) | 1995-06-07 | 2000-08-29 | Sanconix, Inc | Direct sequence frequency ambiguity resolving receiver |
| US5753505A (en) | 1995-07-06 | 1998-05-19 | Emory University | Neuronal progenitor cells and uses thereof |
| US6057846A (en) | 1995-07-14 | 2000-05-02 | Sever, Jr.; Frank | Virtual reality psychophysiological conditioning medium |
| US5707334A (en) * | 1995-08-21 | 1998-01-13 | Young; Robert B. | Method of treating amygdala related transitory disorders |
| AUPN533195A0 (en) * | 1995-09-07 | 1995-10-05 | Cochlear Pty. Limited | Derived threshold and comfort level for auditory prostheses |
| US5649936A (en) | 1995-09-19 | 1997-07-22 | Real; Douglas D. | Stereotactic guide apparatus for use with neurosurgical headframe |
| US5782873A (en) | 1995-10-11 | 1998-07-21 | Trustees Of Boston University | Method and apparatus for improving the function of sensory cells |
| US6480743B1 (en) | 2000-04-05 | 2002-11-12 | Neuropace, Inc. | System and method for adaptive brain stimulation |
| US6944501B1 (en) | 2000-04-05 | 2005-09-13 | Neurospace, Inc. | Neurostimulator involving stimulation strategies and process for using it |
| US20020169485A1 (en) | 1995-10-16 | 2002-11-14 | Neuropace, Inc. | Differential neurostimulation therapy driven by physiological context |
| US6095148A (en) | 1995-11-03 | 2000-08-01 | Children's Medical Center Corporation | Neuronal stimulation using electrically conducting polymers |
| EP0867102A4 (en) | 1995-12-01 | 2000-10-04 | Cochlear Ltd | FEEDBACK DEVICE FOR REGULATING ELECTRODE VOLTAGES IN A COCHLEAR STIMULATOR AND THE LIKE |
| NL1001890C2 (nl) | 1995-12-13 | 1997-06-17 | Cordis Europ | Catheter met plaatvormige elektrode-reeks. |
| US5824030A (en) | 1995-12-21 | 1998-10-20 | Pacesetter, Inc. | Lead with inter-electrode spacing adjustment |
| US6066163A (en) | 1996-02-02 | 2000-05-23 | John; Michael Sasha | Adaptive brain stimulation method and system |
| US6463328B1 (en) | 1996-02-02 | 2002-10-08 | Michael Sasha John | Adaptive brain stimulation method and system |
| US5611350A (en) * | 1996-02-08 | 1997-03-18 | John; Michael S. | Method and apparatus for facilitating recovery of patients in deep coma |
| US6051017A (en) * | 1996-02-20 | 2000-04-18 | Advanced Bionics Corporation | Implantable microstimulator and systems employing the same |
| US6126657A (en) | 1996-02-23 | 2000-10-03 | Somnus Medical Technologies, Inc. | Apparatus for treatment of air way obstructions |
| US5904916A (en) | 1996-03-05 | 1999-05-18 | Hirsch; Alan R. | Use of odorants to alter learning capacity |
| US5833603A (en) | 1996-03-13 | 1998-11-10 | Lipomatrix, Inc. | Implantable biosensing transponder |
| EP0796634B1 (de) | 1996-03-21 | 2005-11-16 | BIOTRONIK Mess- und Therapiegeräte GmbH & Co Ingenieurbüro Berlin | Implantierbare Stimulationselektrode |
| US5702429A (en) | 1996-04-04 | 1997-12-30 | Medtronic, Inc. | Neural stimulation techniques with feedback |
| CA2249602A1 (en) * | 1996-04-04 | 1997-10-16 | Medtronic, Inc. | Living tissue stimulation and recording techniques |
| US5925070A (en) | 1996-04-04 | 1999-07-20 | Medtronic, Inc. | Techniques for adjusting the locus of excitation of electrically excitable tissue |
| US5713922A (en) * | 1996-04-25 | 1998-02-03 | Medtronic, Inc. | Techniques for adjusting the locus of excitation of neural tissue in the spinal cord or brain |
| US5628317A (en) | 1996-04-04 | 1997-05-13 | Medtronic, Inc. | Ultrasonic techniques for neurostimulator control |
| US5683422A (en) | 1996-04-25 | 1997-11-04 | Medtronic, Inc. | Method and apparatus for treating neurodegenerative disorders by electrical brain stimulation |
| US5716377A (en) | 1996-04-25 | 1998-02-10 | Medtronic, Inc. | Method of treating movement disorders by brain stimulation |
| US6094598A (en) | 1996-04-25 | 2000-07-25 | Medtronics, Inc. | Method of treating movement disorders by brain stimulation and drug infusion |
| US5824021A (en) | 1996-04-25 | 1998-10-20 | Medtronic Inc. | Method and apparatus for providing feedback to spinal cord stimulation for angina |
| US5735814A (en) * | 1996-04-30 | 1998-04-07 | Medtronic, Inc. | Techniques of treating neurodegenerative disorders by brain infusion |
| US5711316A (en) * | 1996-04-30 | 1998-01-27 | Medtronic, Inc. | Method of treating movement disorders by brain infusion |
| US5713923A (en) * | 1996-05-13 | 1998-02-03 | Medtronic, Inc. | Techniques for treating epilepsy by brain stimulation and drug infusion |
| US5753506A (en) * | 1996-05-23 | 1998-05-19 | Cns Stem Cell Technology, Inc. | Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals |
| AU3304997A (en) * | 1996-05-31 | 1998-01-05 | Southern Illinois University | Methods of modulating aspects of brain neural plasticity by vagus nerve stimulation |
| US6609031B1 (en) | 1996-06-07 | 2003-08-19 | Advanced Neuromodulation Systems, Inc. | Multiprogrammable tissue stimulator and method |
| US6021352A (en) * | 1996-06-26 | 2000-02-01 | Medtronic, Inc, | Diagnostic testing methods and apparatus for implantable therapy devices |
| US5782798A (en) | 1996-06-26 | 1998-07-21 | Medtronic, Inc. | Techniques for treating eating disorders by brain stimulation and drug infusion |
| US6246912B1 (en) | 1996-06-27 | 2001-06-12 | Sherwood Services Ag | Modulated high frequency tissue modification |
| US5865842A (en) * | 1996-08-29 | 1999-02-02 | Medtronic, Inc. | System and method for anchoring brain stimulation lead or catheter |
| US5797970A (en) | 1996-09-04 | 1998-08-25 | Medtronic, Inc. | System, adaptor and method to provide medical electrical stimulation |
| US5843148A (en) | 1996-09-27 | 1998-12-01 | Medtronic, Inc. | High resolution brain stimulation lead and method of use |
| US5752979A (en) | 1996-11-01 | 1998-05-19 | Medtronic, Inc. | Method of controlling epilepsy by brain stimulation |
| US6057847A (en) | 1996-12-20 | 2000-05-02 | Jenkins; Barry | System and method of image generation and encoding using primitive reprojection |
| US6026326A (en) * | 1997-01-13 | 2000-02-15 | Medtronic, Inc. | Apparatus and method for treating chronic constipation |
| US5871517A (en) * | 1997-01-15 | 1999-02-16 | Somatics, Inc. | Convulsive therapy apparatus to stimulate and monitor the extent of therapeutic value of the treatment |
| US5873849A (en) * | 1997-04-24 | 1999-02-23 | Ichor Medical Systems, Inc. | Electrodes and electrode arrays for generating electroporation inducing electrical fields |
| US6042579A (en) * | 1997-04-30 | 2000-03-28 | Medtronic, Inc. | Techniques for treating neurodegenerative disorders by infusion of nerve growth factors into the brain |
| US5893883A (en) * | 1997-04-30 | 1999-04-13 | Medtronic, Inc. | Portable stimulation screening device for screening therapeutic effect of electrical stimulation on a patient user during normal activities of the patient user |
| US5948007A (en) | 1997-04-30 | 1999-09-07 | Medtronic, Inc. | Dual channel implantation neurostimulation techniques |
| US6128537A (en) | 1997-05-01 | 2000-10-03 | Medtronic, Inc | Techniques for treating anxiety by brain stimulation and drug infusion |
| US5975085A (en) | 1997-05-01 | 1999-11-02 | Medtronic, Inc. | Method of treating schizophrenia by brain stimulation and drug infusion |
| WO1998050107A1 (en) | 1997-05-06 | 1998-11-12 | Christopher Bock | Methods and apparatus for portable delivery of electrical physical therapy modalities to a patient |
| US5861017A (en) | 1997-06-06 | 1999-01-19 | Shriners Hospitals For Children | Portable functional electrical stimulation (FES) system for upper or lower extremity applications |
| US6024702A (en) * | 1997-09-03 | 2000-02-15 | Pmt Corporation | Implantable electrode manufactured with flexible printed circuit |
| US5843150A (en) | 1997-10-08 | 1998-12-01 | Medtronic, Inc. | System and method for providing electrical and/or fluid treatment within a patient's brain |
| US5941906A (en) | 1997-10-15 | 1999-08-24 | Medtronic, Inc. | Implantable, modular tissue stimulator |
| US5938688A (en) | 1997-10-22 | 1999-08-17 | Cornell Research Foundation, Inc. | Deep brain stimulation method |
| US6230049B1 (en) | 1999-08-13 | 2001-05-08 | Neuro Pace, Inc. | Integrated system for EEG monitoring and electrical stimulation with a multiplicity of electrodes |
| US6016449A (en) | 1997-10-27 | 2000-01-18 | Neuropace, Inc. | System for treatment of neurological disorders |
| US6427086B1 (en) | 1997-10-27 | 2002-07-30 | Neuropace, Inc. | Means and method for the intracranial placement of a neurostimulator |
| US6647296B2 (en) | 1997-10-27 | 2003-11-11 | Neuropace, Inc. | Implantable apparatus for treating neurological disorders |
| US6597954B1 (en) | 1997-10-27 | 2003-07-22 | Neuropace, Inc. | System and method for controlling epileptic seizures with spatially separated detection and stimulation electrodes |
| US6459936B2 (en) | 1997-10-27 | 2002-10-01 | Neuropace, Inc. | Methods for responsively treating neurological disorders |
| US6354299B1 (en) * | 1997-10-27 | 2002-03-12 | Neuropace, Inc. | Implantable device for patient communication |
| DE19750043A1 (de) | 1997-11-12 | 1999-05-20 | Johann W Prof Dr Bartha | Neuartige Cuff-Elektrode und Verfahren zur Erzeugung dieser |
| US6128527A (en) | 1997-12-03 | 2000-10-03 | University Of Iowa Research Foundation | Apparatus and method of analyzing electrical brain activity |
| US6011996A (en) * | 1998-01-20 | 2000-01-04 | Medtronic, Inc | Dual electrode lead and method for brain target localization in functional stereotactic brain surgery |
| US6205361B1 (en) * | 1998-02-10 | 2001-03-20 | Advanced Bionics Corporation | Implantable expandable multicontact electrodes |
| US6631295B2 (en) | 1998-02-13 | 2003-10-07 | University Of Iowa Research Foundation | System and method for diagnosing and/or reducing tinnitus |
| US6078838A (en) | 1998-02-13 | 2000-06-20 | University Of Iowa Research Foundation | Pseudospontaneous neural stimulation system and method |
| US6221908B1 (en) * | 1998-03-12 | 2001-04-24 | Scientific Learning Corporation | System for stimulating brain plasticity |
| US6295474B1 (en) | 1998-03-13 | 2001-09-25 | Intermedics Inc. | Defibrillator housing with conductive polymer coating |
| US6058331A (en) | 1998-04-27 | 2000-05-02 | Medtronic, Inc. | Apparatus and method for treating peripheral vascular disease and organ ischemia by electrical stimulation with closed loop feedback control |
| US6421566B1 (en) | 1998-04-30 | 2002-07-16 | Medtronic, Inc. | Selective dorsal column stimulation in SCS, using conditioning pulses |
| US6018682A (en) * | 1998-04-30 | 2000-01-25 | Medtronic, Inc. | Implantable seizure warning system |
| US6161047A (en) | 1998-04-30 | 2000-12-12 | Medtronic Inc. | Apparatus and method for expanding a stimulation lead body in situ |
| US6319241B1 (en) | 1998-04-30 | 2001-11-20 | Medtronic, Inc. | Techniques for positioning therapy delivery elements within a spinal cord or a brain |
| US6006124A (en) | 1998-05-01 | 1999-12-21 | Neuropace, Inc. | Means and method for the placement of brain electrodes |
| US5938689A (en) | 1998-05-01 | 1999-08-17 | Neuropace, Inc. | Electrode configuration for a brain neuropacemaker |
| US5886769A (en) * | 1998-05-18 | 1999-03-23 | Zolten; A. J. | Method of training and rehabilitating brain function using hemi-lenses |
| US6198958B1 (en) * | 1998-06-11 | 2001-03-06 | Beth Israel Deaconess Medical Center, Inc. | Method and apparatus for monitoring a magnetic resonance image during transcranial magnetic stimulation |
| US7890176B2 (en) | 1998-07-06 | 2011-02-15 | Boston Scientific Neuromodulation Corporation | Methods and systems for treating chronic pelvic pain |
| US6035236A (en) * | 1998-07-13 | 2000-03-07 | Bionergy Therapeutics, Inc. | Methods and apparatus for electrical microcurrent stimulation therapy |
| US6104960A (en) | 1998-07-13 | 2000-08-15 | Medtronic, Inc. | System and method for providing medical electrical stimulation to a portion of the nervous system |
| US6366813B1 (en) * | 1998-08-05 | 2002-04-02 | Dilorenzo Daniel J. | Apparatus and method for closed-loop intracranical stimulation for optimal control of neurological disease |
| US7277758B2 (en) | 1998-08-05 | 2007-10-02 | Neurovista Corporation | Methods and systems for predicting future symptomatology in a patient suffering from a neurological or psychiatric disorder |
| US6304787B1 (en) | 1998-08-26 | 2001-10-16 | Advanced Bionics Corporation | Cochlear electrode array having current-focusing and tissue-treating features |
| WO2000012042A1 (en) | 1998-08-27 | 2000-03-09 | Novavision Ag | Process and device for the training of human vision |
| US6190893B1 (en) * | 1998-09-18 | 2001-02-20 | Massachusetts Institute Of Technology | Electroactive materials for stimulation of biological activity of bone marrow stromal cells |
| US6569654B2 (en) | 1998-09-18 | 2003-05-27 | Massachusetts Institute Of Technology | Electroactive materials for stimulation of biological activity of stem cells |
| US6615065B1 (en) | 1998-10-13 | 2003-09-02 | Somanetics Corporation | Multi-channel non-invasive tissue oximeter |
| US7062330B1 (en) * | 1998-10-26 | 2006-06-13 | Boveja Birinder R | Electrical stimulation adjunct (Add-ON) therapy for urinary incontinence and urological disorders using implanted lead stimulus-receiver and an external pulse generator |
| US20060217782A1 (en) | 1998-10-26 | 2006-09-28 | Boveja Birinder R | Method and system for cortical stimulation to provide adjunct (ADD-ON) therapy for stroke, tinnitus and other medical disorders using implantable and external components |
| US6253109B1 (en) | 1998-11-05 | 2001-06-26 | Medtronic Inc. | System for optimized brain stimulation |
| US6161044A (en) | 1998-11-23 | 2000-12-12 | Synaptic Corporation | Method and apparatus for treating chronic pain syndromes, tremor, dementia and related disorders and for inducing electroanesthesia using high frequency, high intensity transcutaneous electrical nerve stimulation |
| US6507755B1 (en) * | 1998-12-01 | 2003-01-14 | Neurometrix, Inc. | Apparatus and method for stimulating human tissue |
| US6052624A (en) * | 1999-01-07 | 2000-04-18 | Advanced Bionics Corporation | Directional programming for implantable electrode arrays |
| JP4288009B2 (ja) | 1999-03-24 | 2009-07-01 | ロイド アール． サベルスキ， | 痛みの軽減及び／又は筋肉の再訓練を行うための装置及び方法 |
| US6210417B1 (en) * | 1999-04-29 | 2001-04-03 | Medtronic, Inc. | Medical lead positioning and anchoring system |
| US6214016B1 (en) | 1999-04-29 | 2001-04-10 | Medtronic, Inc. | Medical instrument positioning device internal to a catheter or lead and method of use |
| US6055456A (en) * | 1999-04-29 | 2000-04-25 | Medtronic, Inc. | Single and multi-polar implantable lead for sacral nerve electrical stimulation |
| US6353762B1 (en) * | 1999-04-30 | 2002-03-05 | Medtronic, Inc. | Techniques for selective activation of neurons in the brain, spinal cord parenchyma or peripheral nerve |
| US6176242B1 (en) | 1999-04-30 | 2001-01-23 | Medtronic Inc | Method of treating manic depression by brain infusion |
| EP1180056B1 (en) | 1999-05-11 | 2003-11-12 | Exogen, Inc. | Apparatus for ultrasonic treatment of reflex sympathetic dystrophy |
| US6505075B1 (en) * | 1999-05-29 | 2003-01-07 | Richard L. Weiner | Peripheral nerve stimulation method |
| US6161045A (en) | 1999-06-01 | 2000-12-12 | Neuropace, Inc. | Method for determining stimulation parameters for the treatment of epileptic seizures |
| US6633780B1 (en) | 1999-06-07 | 2003-10-14 | The Johns Hopkins University | Cardiac shock electrode system and corresponding implantable defibrillator system |
| US6539263B1 (en) | 1999-06-11 | 2003-03-25 | Cornell Research Foundation, Inc. | Feedback mechanism for deep brain stimulation |
| US6301493B1 (en) | 1999-07-10 | 2001-10-09 | Physiometrix, Inc. | Reservoir electrodes for electroencephalograph headgear appliance |
| US6516227B1 (en) | 1999-07-27 | 2003-02-04 | Advanced Bionics Corporation | Rechargeable spinal cord stimulator system |
| US6381496B1 (en) * | 1999-10-01 | 2002-04-30 | Advanced Bionics Corporation | Parameter context switching for an implanted device |
| US6236892B1 (en) | 1999-10-07 | 2001-05-22 | Claudio A. Feler | Spinal cord stimulation lead |
| US6499488B1 (en) | 1999-10-28 | 2002-12-31 | Winchester Development Associates | Surgical sensor |
| US6375666B1 (en) * | 1999-12-09 | 2002-04-23 | Hans Alois Mische | Methods and devices for treatment of neurological disorders |
| US6764498B2 (en) | 1999-12-09 | 2004-07-20 | Hans Alois Mische | Methods and devices for treatment of neurological disorders |
| US7300449B2 (en) * | 1999-12-09 | 2007-11-27 | Mische Hans A | Methods and devices for the treatment of neurological and physiological disorders |
| AU1547101A (en) | 1999-11-26 | 2001-06-04 | Applied Spectral Imaging Ltd. | System and method for functional brain mapping and an oxygen saturation difference map algorithm for effecting same |
| WO2001039831A1 (en) | 1999-12-06 | 2001-06-07 | Advanced Bionics Corporation | Implantable device programmer |
| US6873872B2 (en) * | 1999-12-07 | 2005-03-29 | George Mason University | Adaptive electric field modulation of neural systems |
| JP2003516206A (ja) * | 1999-12-07 | 2003-05-13 | クラスノウ インスティテュート | 神経系の適応性電場調整 |
| US6356786B1 (en) * | 2000-01-20 | 2002-03-12 | Electrocore Techniques, Llc | Method of treating palmar hyperhydrosis by electrical stimulation of the sympathetic nervous chain |
| US6356792B1 (en) * | 2000-01-20 | 2002-03-12 | Electro Core Technologies, Llc | Skull mounted electrode lead securing assembly |
| US6907296B1 (en) | 2000-02-15 | 2005-06-14 | Pacesetter, Inc. | Implantable cardiac lead having convenient implant location identification and method of manufacture |
| US6487450B1 (en) | 2000-02-24 | 2002-11-26 | Cedars-Sinai Medical Center | System and method for preventing Sudden Cardiac Death by nerve sprouting from right stellate ganglion |
| US6708064B2 (en) | 2000-02-24 | 2004-03-16 | Ali R. Rezai | Modulation of the brain to affect psychiatric disorders |
| US6609030B1 (en) | 2000-02-24 | 2003-08-19 | Electrocore Techniques, Llc | Method of treating psychiatric diseases by neuromodulation within the dorsomedial thalamus |
| US6418344B1 (en) | 2000-02-24 | 2002-07-09 | Electrocore Techniques, Llc | Method of treating psychiatric disorders by electrical stimulation within the orbitofrontal cerebral cortex |
| US6473639B1 (en) | 2000-03-02 | 2002-10-29 | Neuropace, Inc. | Neurological event detection procedure using processed display channel based algorithms and devices incorporating these procedures |
| US6810286B2 (en) | 2000-03-06 | 2004-10-26 | Medtronic, Inc | Stimulation for delivery of molecular therapy |
| US6430443B1 (en) * | 2000-03-21 | 2002-08-06 | Manuel L. Karell | Method and apparatus for treating auditory hallucinations |
| US6466822B1 (en) | 2000-04-05 | 2002-10-15 | Neuropace, Inc. | Multimodal neurostimulator and process of using it |
| US6353754B1 (en) * | 2000-04-24 | 2002-03-05 | Neuropace, Inc. | System for the creation of patient specific templates for epileptiform activity detection |
| WO2001093750A2 (en) * | 2000-06-07 | 2001-12-13 | Univ New York | Methods for diagnosing and treating thalamocortical dysrhythmia |
| US6549814B1 (en) * | 2000-06-09 | 2003-04-15 | Juergen Strutz | Blade electrode array for insertion under soft tissue of lateral wall of cochlea |
| WO2001097906A2 (en) | 2000-06-20 | 2001-12-27 | Advanced Bionics Corporation | Apparatus for treatment of mood and/or anxiety disorders by electrical brain stimulation and/or drug infusion |
| US20030125786A1 (en) | 2000-07-13 | 2003-07-03 | Gliner Bradford Evan | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
| US7756584B2 (en) | 2000-07-13 | 2010-07-13 | Advanced Neuromodulation Systems, Inc. | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
| US7305268B2 (en) | 2000-07-13 | 2007-12-04 | Northstar Neurscience, Inc. | Systems and methods for automatically optimizing stimulus parameters and electrode configurations for neuro-stimulators |
| US7672730B2 (en) * | 2001-03-08 | 2010-03-02 | Advanced Neuromodulation Systems, Inc. | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
| US20050021118A1 (en) * | 2000-07-13 | 2005-01-27 | Chris Genau | Apparatuses and systems for applying electrical stimulation to a patient |
| US7024247B2 (en) | 2001-10-15 | 2006-04-04 | Northstar Neuroscience, Inc. | Systems and methods for reducing the likelihood of inducing collateral neural activity during neural stimulation threshold test procedures |
| US7831305B2 (en) * | 2001-10-15 | 2010-11-09 | Advanced Neuromodulation Systems, Inc. | Neural stimulation system and method responsive to collateral neural activity |
| US7236831B2 (en) * | 2000-07-13 | 2007-06-26 | Northstar Neuroscience, Inc. | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
| US7010351B2 (en) * | 2000-07-13 | 2006-03-07 | Northstar Neuroscience, Inc. | Methods and apparatus for effectuating a lasting change in a neural-function of a patient |
| US7146217B2 (en) * | 2000-07-13 | 2006-12-05 | Northstar Neuroscience, Inc. | Methods and apparatus for effectuating a change in a neural-function of a patient |
| US20040176831A1 (en) | 2000-07-13 | 2004-09-09 | Gliner Bradford Evan | Apparatuses and systems for applying electrical stimulation to a patient |
| US6497699B1 (en) | 2000-08-09 | 2002-12-24 | The Research Foundation Of State University Of New York | Hybrid neuroprosthesis for the treatment of brain disorders |
| DE10039240A1 (de) | 2000-08-11 | 2002-02-28 | Hans Ulrich May | Elektrotherapeutisches Gerät |
| US6591138B1 (en) | 2000-08-31 | 2003-07-08 | Neuropace, Inc. | Low frequency neurostimulator for the treatment of neurological disorders |
| JP2002072309A (ja) * | 2000-09-01 | 2002-03-12 | Canon Inc | カメラ及びカメラシステム |
| US6405079B1 (en) | 2000-09-22 | 2002-06-11 | Mehdi M. Ansarinia | Stimulation method for the dural venous sinuses and adjacent dura for treatment of medical conditions |
| US6871098B2 (en) * | 2000-10-30 | 2005-03-22 | Medtronic, Inc. | Method for treating obsessive-compulsive disorder with electrical stimulation of the brain internal capsule |
| US6529774B1 (en) * | 2000-11-09 | 2003-03-04 | Neuropace, Inc. | Extradural leads, neurostimulator assemblies, and processes of using them for somatosensory and brain stimulation |
| US6922590B1 (en) | 2000-11-21 | 2005-07-26 | Advanced Bionics Corporation | Systems and methods for treatment of diabetes by electrical brain stimulation and/or drug infusion |
| US6788975B1 (en) | 2001-01-30 | 2004-09-07 | Advanced Bionics Corporation | Fully implantable miniature neurostimulator for stimulation as a therapy for epilepsy |
| US6735475B1 (en) | 2001-01-30 | 2004-05-11 | Advanced Bionics Corporation | Fully implantable miniature neurostimulator for stimulation as a therapy for headache and/or facial pain |
| US7149586B2 (en) | 2002-03-28 | 2006-12-12 | Second Sight Medical Products, Inc. | Variable pitch electrode array |
| US7299096B2 (en) | 2001-03-08 | 2007-11-20 | Northstar Neuroscience, Inc. | System and method for treating Parkinson's Disease and other movement disorders |
| US7112319B2 (en) | 2001-04-06 | 2006-09-26 | The Research Foundation Of The City University Of New York | Identification, diagnosis, and treatment of neuropathologies, neurotoxicities, tumors, and brain and spinal cord injuries using microelectrodes with microvoltammetry |
| US6684105B2 (en) * | 2001-08-31 | 2004-01-27 | Biocontrol Medical, Ltd. | Treatment of disorders by unidirectional nerve stimulation |
| US6839594B2 (en) * | 2001-04-26 | 2005-01-04 | Biocontrol Medical Ltd | Actuation and control of limbs through motor nerve stimulation |
| AU2002255248A1 (en) | 2001-04-27 | 2002-11-11 | Alexander Grinshpoon | Diagnosis, treatment and research of mental disorders |
| US20060241717A1 (en) | 2001-08-30 | 2006-10-26 | Whitehurst Todd K | Treatment of movement disorders by extra dural motor cortex stimulation |
| WO2003026738A1 (en) | 2001-09-28 | 2003-04-03 | Northstar Neuroscience, Inc. | Methods and apparatus for electrically stimulating cells implanted in the nervous system |
| AU2002334749A1 (en) * | 2001-09-28 | 2003-04-07 | Northstar Neuroscience, Inc. | Methods and implantable apparatus for electrical therapy |
| US6944497B2 (en) | 2001-10-31 | 2005-09-13 | Medtronic, Inc. | System and method of treating stuttering by neuromodulation |
| US7050856B2 (en) | 2002-01-11 | 2006-05-23 | Medtronic, Inc. | Variation of neural-stimulation parameters |
| US7110820B2 (en) | 2002-02-05 | 2006-09-19 | Tcheng Thomas K | Responsive electrical stimulation for movement disorders |
| US7221981B2 (en) | 2002-03-28 | 2007-05-22 | Northstar Neuroscience, Inc. | Electrode geometries for efficient neural stimulation |
| US7146222B2 (en) | 2002-04-15 | 2006-12-05 | Neurospace, Inc. | Reinforced sensing and stimulation leads and use in detection systems |
| US20060004423A1 (en) * | 2002-05-09 | 2006-01-05 | Boveja Birinder R | Methods and systems to provide therapy or alleviate symptoms of chronic headache, transformed migraine, and occipital neuralgia by providing rectangular and/or complex electrical pulses to occipital nerves |
| US20050154426A1 (en) | 2002-05-09 | 2005-07-14 | Boveja Birinder R. | Method and system for providing therapy for neuropsychiatric and neurological disorders utilizing transcranical magnetic stimulation and pulsed electrical vagus nerve(s) stimulation |
| US20050182453A1 (en) | 2002-05-24 | 2005-08-18 | Whitehurst Todd K. | Treatment of epilepsy by high frequency electrical stimulation and/or drug stimulation |
| CA2488882A1 (en) * | 2002-06-13 | 2003-12-24 | Atlantic Medical, Inc. | Transcutaneous electrical nerve stimulation device and method using microcurrent |
| EP2468358B1 (en) | 2002-06-28 | 2013-08-07 | Boston Scientific Neuromodulation Corporation | Microstimulator having self-contained power source and bi-directional telemetry system |
| US7006859B1 (en) | 2002-07-20 | 2006-02-28 | Flint Hills Scientific, L.L.C. | Unitized electrode with three-dimensional multi-site, multi-modal capabilities for detection and control of brain state changes |
| US6934580B1 (en) | 2002-07-20 | 2005-08-23 | Flint Hills Scientific, L.L.C. | Stimulation methodologies and apparatus for control of brain states |
| US20040092809A1 (en) | 2002-07-26 | 2004-05-13 | Neurion Inc. | Methods for measurement and analysis of brain activity |
| US7471974B2 (en) | 2002-09-13 | 2008-12-30 | Brainlab Ag | Method for planning stimulation of hyper/hypometabolic cortical areas |
| US20050075679A1 (en) | 2002-09-30 | 2005-04-07 | Gliner Bradford E. | Methods and apparatuses for treating neurological disorders by electrically stimulating cells implanted in the nervous system |
| US20040082847A1 (en) * | 2002-10-23 | 2004-04-29 | Mcdermott Kathleen B. | System and methods for identifying brain regions supporting language |
| US7236830B2 (en) | 2002-12-10 | 2007-06-26 | Northstar Neuroscience, Inc. | Systems and methods for enhancing or optimizing neural stimulation therapy for treating symptoms of Parkinson's disease and/or other movement disorders |
| US20050075680A1 (en) | 2003-04-18 | 2005-04-07 | Lowry David Warren | Methods and systems for intracranial neurostimulation and/or sensing |
| US7302298B2 (en) | 2002-11-27 | 2007-11-27 | Northstar Neuroscience, Inc | Methods and systems employing intracranial electrodes for neurostimulation and/or electroencephalography |
| AU2003297761A1 (en) * | 2002-12-09 | 2004-06-30 | Northstar Neuroscience, Inc. | Methods for treating neurological language disorders |
| US6959215B2 (en) | 2002-12-09 | 2005-10-25 | Northstar Neuroscience, Inc. | Methods for treating essential tremor |
| US7596408B2 (en) * | 2002-12-09 | 2009-09-29 | Medtronic, Inc. | Implantable medical device with anti-infection agent |
| EP1620166A4 (en) * | 2003-04-24 | 2013-01-02 | Advanced Neuromodulation Sys | SYSTEMS AND METHOD FOR FACILITATING AND / OR EFFECTING DEVELOPMENT, REHABILITATION, RESTORATION AND / OR RECOVERY OF THE SEWING FUNCTION THROUGH NEURAL STIMULATION |
| US7065412B2 (en) | 2003-04-25 | 2006-06-20 | Medtronic, Inc. | Implantable trial neurostimulation device |
| US7463928B2 (en) | 2003-04-25 | 2008-12-09 | Medtronic, Inc. | Identifying combinations of electrodes for neurostimulation therapy |
| US7107104B2 (en) | 2003-05-30 | 2006-09-12 | Medtronic, Inc. | Implantable cortical neural lead and method |
| CA2432810A1 (en) * | 2003-06-19 | 2004-12-19 | Andres M. Lozano | Method of treating depression, mood disorders and anxiety disorders by brian infusion |
| WO2005011805A2 (en) | 2003-08-01 | 2005-02-10 | Northstar Neuroscience, Inc. | Apparatus and methods for applying neural stimulation to a patient |
| FR2860722B1 (fr) | 2003-10-14 | 2006-09-22 | Commissariat Energie Atomique | Dispositif d'electro-stimulation cerebrale ameliore |
| US7187968B2 (en) * | 2003-10-23 | 2007-03-06 | Duke University | Apparatus for acquiring and transmitting neural signals and related methods |
| EP1694403A2 (en) | 2003-11-20 | 2006-08-30 | Advanced Neuromodulation Systems, Inc. | Electrical stimulation system, lead, and method providing reduced neuroplasticity effects |
| US8093205B2 (en) | 2003-12-01 | 2012-01-10 | Medtronic, Inc. | Method for treating a stroke by implanting a first therapy delivery element in the CNS and a second therapy delivery element in a damaged tissue of the CNS to promote neurogenesis |
| US7107097B2 (en) | 2004-01-14 | 2006-09-12 | Northstar Neuroscience, Inc. | Articulated neural electrode assembly |
| WO2005087314A1 (en) * | 2004-03-11 | 2005-09-22 | Advanced Neuromodulation Systems, Inc. | Brain stimulation system and method |
| US7313442B2 (en) | 2004-04-30 | 2007-12-25 | Advanced Neuromodulation Systems, Inc. | Method of treating mood disorders and/or anxiety disorders by brain stimulation |
| CA2573763A1 (en) * | 2004-07-15 | 2006-02-23 | Northstar Neuroscience, Inc. | Systems and methods for enhancing or affecting neural stimulation efficiency and/or efficacy |
| US20060020297A1 (en) | 2004-07-20 | 2006-01-26 | Gerber Martin T | Neurostimulation system with distributed stimulators |
| US20050154425A1 (en) | 2004-08-19 | 2005-07-14 | Boveja Birinder R. | Method and system to provide therapy for neuropsychiatric disorders and cognitive impairments using gradient magnetic pulses to the brain and pulsed electrical stimulation to vagus nerve(s) |
| US7603174B2 (en) | 2004-10-21 | 2009-10-13 | Advanced Neuromodulation Systems, Inc. | Stimulation of the amygdalohippocampal complex to treat neurological conditions |
| US20060106430A1 (en) | 2004-11-12 | 2006-05-18 | Brad Fowler | Electrode configurations for reducing invasiveness and/or enhancing neural stimulation efficacy, and associated methods |
| US7565200B2 (en) | 2004-11-12 | 2009-07-21 | Advanced Neuromodulation Systems, Inc. | Systems and methods for selecting stimulation sites and applying treatment, including treatment of symptoms of Parkinson's disease, other movement disorders, and/or drug side effects |
| US8000795B2 (en) | 2004-12-17 | 2011-08-16 | Lozano Andres M | Cognitive function within a human brain |
| WO2006083744A1 (en) | 2005-01-31 | 2006-08-10 | Medtronic, Inc. | Anchoring of a medical device component adjacent a dura of the brain or spinal cord |
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2004
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- 2004-08-02 US US10/910,775 patent/US7684866B2/en not_active Expired - Fee Related
- 2004-08-02 CA CA002534363A patent/CA2534363A1/en not_active Abandoned
- 2004-08-02 JP JP2006522666A patent/JP2007501067A/ja active Pending
- 2004-08-02 AU AU2004261290A patent/AU2004261290A1/en not_active Abandoned
- 2004-08-02 EP EP04779931A patent/EP1654032A2/en not_active Withdrawn
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Also Published As
| Publication number | Publication date |
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| JP2007501067A (ja) | 2007-01-25 |
| US20060190056A1 (en) | 2006-08-24 |
| EP1654032A2 (en) | 2006-05-10 |
| US7684866B2 (en) | 2010-03-23 |
| US8126562B2 (en) | 2012-02-28 |
| US20050070971A1 (en) | 2005-03-31 |
| CA2534363A1 (en) | 2005-02-10 |
| WO2005011805A2 (en) | 2005-02-10 |
| WO2005011805A3 (en) | 2005-10-27 |
| US20090182391A1 (en) | 2009-07-16 |
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