AU2004247138B2 - Synergistic combinations including N-acylated 4-hydroxyphenylamine derivatives and caffeine - Google Patents

Synergistic combinations including N-acylated 4-hydroxyphenylamine derivatives and caffeine Download PDF

Info

Publication number
AU2004247138B2
AU2004247138B2 AU2004247138A AU2004247138A AU2004247138B2 AU 2004247138 B2 AU2004247138 B2 AU 2004247138B2 AU 2004247138 A AU2004247138 A AU 2004247138A AU 2004247138 A AU2004247138 A AU 2004247138A AU 2004247138 B2 AU2004247138 B2 AU 2004247138B2
Authority
AU
Australia
Prior art keywords
composition according
opioid analgesic
analgesic
opioid
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2004247138A
Other languages
English (en)
Other versions
AU2004247138A1 (en
Inventor
Nicolas G. Bazan
Julio Alvarez Builla
Dennis Paul
Carlos Sunkel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Louisiana State University
Original Assignee
Louisiana State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Louisiana State University filed Critical Louisiana State University
Publication of AU2004247138A1 publication Critical patent/AU2004247138A1/en
Assigned to THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE reassignment THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE Request for Assignment Assignors: THE FOUNDATION FOR THE LSU HEALTH SCIENCES CENTER
Assigned to BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE reassignment BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE Alteration of Name(s) of Applicant(s) under S113 Assignors: THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
Application granted granted Critical
Publication of AU2004247138B2 publication Critical patent/AU2004247138B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/428—Thiazoles condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)
  • Seasonings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2004247138A 2003-06-12 2004-06-10 Synergistic combinations including N-acylated 4-hydroxyphenylamine derivatives and caffeine Ceased AU2004247138B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/459,911 2003-06-12
US10/459,911 US7064140B2 (en) 2002-11-12 2003-06-12 Synergistic combinations including N-acylated 4-Hydroxyphenylamine derivatives and caffeine
PCT/US2004/018514 WO2004110440A1 (en) 2003-06-12 2004-06-10 Synergistic combinations including n-acylated 4-hydroxyphenylamine derivatives and caffeine

Publications (2)

Publication Number Publication Date
AU2004247138A1 AU2004247138A1 (en) 2004-12-23
AU2004247138B2 true AU2004247138B2 (en) 2009-03-19

Family

ID=33510895

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2004247138A Ceased AU2004247138B2 (en) 2003-06-12 2004-06-10 Synergistic combinations including N-acylated 4-hydroxyphenylamine derivatives and caffeine

Country Status (9)

Country Link
US (1) US7064140B2 (enExample)
EP (1) EP1635825B1 (enExample)
JP (1) JP2007503473A (enExample)
AT (1) ATE409478T1 (enExample)
AU (1) AU2004247138B2 (enExample)
CA (1) CA2531829A1 (enExample)
DE (1) DE602004016848D1 (enExample)
ES (1) ES2315679T3 (enExample)
WO (1) WO2004110440A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006053012A2 (en) * 2004-11-10 2006-05-18 Trinity Laboratories, Inc. Novel pharmaceutical compositions for treating acquired chronic pain and associated dysphoria
US8026266B2 (en) * 2005-11-08 2011-09-27 Arcion Therapeutics, Inc. Treatment of length dependent neuropathy
TWI392670B (zh) * 2006-06-22 2013-04-11 Ucb Pharma Gmbh 經取代的２-胺基萘滿之於製造用於預防、減緩及／或治療各種類型疼痛之藥物上的用途
WO2009021058A2 (en) 2007-08-06 2009-02-12 Trinity Labortories, Inc. Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996032940A1 (en) * 1995-04-21 1996-10-24 Lsu Medical Center Foundation New n-acylated 4-hydroxyphenylamine derivatives with analgesic properties and pharmaceutical compositions containing them

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6864271B2 (en) * 2002-11-12 2005-03-08 The Foundation For The Lsu Health Sciences Center Synergistic combinations including N-acylated 4-hydroxyphenylamine derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996032940A1 (en) * 1995-04-21 1996-10-24 Lsu Medical Center Foundation New n-acylated 4-hydroxyphenylamine derivatives with analgesic properties and pharmaceutical compositions containing them

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
VIGNON, E et al. Semaine Des Hopitaux, Vol.75(13-14): 419-425. 1999 *

Also Published As

Publication number Publication date
EP1635825A1 (en) 2006-03-22
WO2004110440A1 (en) 2004-12-23
JP2007503473A (ja) 2007-02-22
CA2531829A1 (en) 2004-12-23
ES2315679T3 (es) 2009-04-01
AU2004247138A1 (en) 2004-12-23
US7064140B2 (en) 2006-06-20
ATE409478T1 (de) 2008-10-15
EP1635825B1 (en) 2008-10-01
DE602004016848D1 (de) 2008-11-13
US20040254207A1 (en) 2004-12-16

Similar Documents

Publication Publication Date Title
EP1572204B1 (en) Synergistic compositions with analgesic properties comprising n-acylated 4-hydroxyphenylamine derivatives
EP0149544B1 (en) Pharmaceutical products providing enhanced analgesia
JP2006508137A5 (enExample)
CA2228249C (en) Pain-alleviating drug composition and method for alleviating pain
EP0149545B1 (en) Pharmaceutical products providing enhanced analgesia
CA2381797C (en) Composition comprising a tramadol material and an anticonvulsant drug
JP2000508341A (ja) 片頭痛の治療法及び薬効の強化組成物
EP1161263A1 (en) Analgesic compositions comprising anti-epileptic compounds and methods of using same
CA2544648A1 (en) Analgesic compounds, their synthesis and pharmaceutical compositions containing them
CA2169718C (en) The primary and secondary neuroprotective effect of flupirtine in neurodegenerative diseases
WO2001093852A2 (en) Method of treating pain using nalbuphine and opioid antagonists
EP1635825B1 (en) Synergistic combinations including n-acylated 4-hydroxyphenylamine derivatives and caffeine
AU2004233582B2 (en) Pharmaceutical compositon comprising a cathepsin S inhibitor and an opioid
EP1797883A2 (en) Pharmaceutical composition comprising a cathepsin S inhibitor and an opioid

Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVER

Free format text: FORMER APPLICANT(S): THE FOUNDATION FOR THE LSU HEALTH SCIENCES CENTER

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired